What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Pramoxine Hydrochloride 1%
Water
Skin ConditioningGlycerin
HumectantPetrolatum
EmollientCetyl Alcohol
EmollientButyrospermum Parkii Butter
Skin ConditioningCetearyl Alcohol
EmollientPEG-100 Stearate
SurfactantGlyceryl Stearate
EmollientIsopropyl Myristate
EmollientStearic Acid
CleansingDimethicone
EmollientPalmitic Acid
EmollientPotassium Phosphate
BufferingCeramide NP
Skin ConditioningCeramide AP
Skin ConditioningCeramide EOP
Skin ConditioningCarbomer
Emulsion StabilisingBehentrimonium Methosulfate
SurfactantSodium Hydroxide
BufferingMyristic Acid
CleansingSodium Lauroyl Lactylate
EmulsifyingCholesterol
EmollientTasmannia Lanceolata Fruit Extract
Skin ConditioningPhenoxyethanol
PreservativeDipotassium Phosphate
BufferingDisodium EDTA
ChelatingAlcohol Denat.
AntimicrobialHydrolyzed Hyaluronic Acid
HumectantCitric Acid
BufferingXanthan Gum
EmulsifyingPhytosphingosine
Skin ConditioningEthylhexylglycerin
Skin ConditioningPramoxine Hydrochloride 1%, Water, Glycerin, Petrolatum, Cetyl Alcohol, Butyrospermum Parkii Butter, Cetearyl Alcohol, PEG-100 Stearate, Glyceryl Stearate, Isopropyl Myristate, Stearic Acid, Dimethicone, Palmitic Acid, Potassium Phosphate, Ceramide NP, Ceramide AP, Ceramide EOP, Carbomer, Behentrimonium Methosulfate, Sodium Hydroxide, Myristic Acid, Sodium Lauroyl Lactylate, Cholesterol, Tasmannia Lanceolata Fruit Extract, Phenoxyethanol, Dipotassium Phosphate, Disodium EDTA, Alcohol Denat., Hydrolyzed Hyaluronic Acid, Citric Acid, Xanthan Gum, Phytosphingosine, Ethylhexylglycerin
Water
Skin ConditioningGlycerin
HumectantHydrogenated Coco-Glycerides
EmollientIsopropyl Palmitate
EmollientTriisostearin
Skin ConditioningStearyl Alcohol
EmollientLaureth-9
EmulsifyingPalmitic Acid
EmollientStearic Acid
CleansingDistarch Phosphate
AbsorbentDimethicone
EmollientGlyceryl Stearate
EmollientCetyl Alcohol
EmollientPEG-100 Stearate
SurfactantSorbitan Stearate
EmulsifyingArginine Hcl
Skin ConditioningTocopherol
AntioxidantCeramide NP
Skin ConditioningSodium Citrate
BufferingCitric Acid
BufferingMyristic Acid
CleansingArachidic Acid
CleansingOleic Acid
EmollientBenzyl Alcohol
PerfumingPentylene Glycol
Skin ConditioningEthylhexylglycerin
Skin ConditioningTrans-2-Tert-Butylcyclohexanol
PerfumingMenthoxypropanediol
MaskingCarbomer
Emulsion StabilisingSodium Hydroxide
BufferingTrisodium EDTA
ChelatingWater, Glycerin, Hydrogenated Coco-Glycerides, Isopropyl Palmitate, Triisostearin, Stearyl Alcohol, Laureth-9, Palmitic Acid, Stearic Acid, Distarch Phosphate, Dimethicone, Glyceryl Stearate, Cetyl Alcohol, PEG-100 Stearate, Sorbitan Stearate, Arginine Hcl, Tocopherol, Ceramide NP, Sodium Citrate, Citric Acid, Myristic Acid, Arachidic Acid, Oleic Acid, Benzyl Alcohol, Pentylene Glycol, Ethylhexylglycerin, Trans-2-Tert-Butylcyclohexanol, Menthoxypropanediol, Carbomer, Sodium Hydroxide, Trisodium EDTA
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Learn more about CarbomerCeramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Learn more about Ceramide NPCetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.
Its main roles are:
Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.
The FDA allows products labeled "alcohol-free" to have fatty alcohols.
This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.
Learn more about Cetyl AlcoholCitric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.
Learn more about Citric AcidDimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinGlyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.
Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.
This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.
A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.
Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.
Fun fact: The human body also creates Glyceryl Stearate naturally.
Learn more about Glyceryl StearateMyristic Acid, aka tetradecanoic acid, is a naturally occurring fatty acid found in coconut oil, milk fat, and palm oil.
In skincare, it is an:
Research indicates that this ingredient posts a low risk of irritation and sensitization.
Industry survey data collected for this ingredient puts real-world usage concentrations anywhere from 0.00002% to 20% (most of the high end sits in rinse-off products).
Myristic Acid is not a recognized contact allergen and there are no published case reports of allergic contact dermatitis to it. Human testing found it to be non-irritating at 100% and at 40-50% in mineral oil. There are complaints about high-Myristic-acid cleansers leaving a tight feeling behind, but that has more to do with soap chemistry and pH than an allergy.
This ingredient does have a comedogenic rating of 3, but this doesn't mean a formula with this ingredient will clog pores.
Human testing has proved that any finished product with this ingredient won't automatically make you break out; it really comes down to concentration, formula, and your skin. Some people still find it breaks them out. So if that's you, definitely trust your skin.
Since myristic acid is a C14 fatty acid, it falls within the range that Malassezia can metabolize (C11-24), and therefore may not be fungal acne safe.
Learn more about Myristic AcidPalmitic Acid is a fatty acid naturally found in our skin and in many plant and animal sources.
In cosmetics, it is usually derived from palm oil. It serves many purposes in skincare, acting as a cleanser, emollient, and emulsifier.
Interestingly, topically applied Palmitic Acid can be elongated into longer chain fatty acids and ceramides. A 2019 study found low levels of Palmitic Acid lead to slower development of cells, suggesting it plays a role in keeping your skin's renewal process on track.
The CIR (Cosmetic Ingredient Review) panel determined it safe as used in cosmetics at concentrations up to 13%. It is non-irritating and non-sensitizing in clinical studies.
The culprit behind fungal acne, the Malassezia yeast, feeds on fatty acids with carbon chain lengths between C11-C24. Palmitic Acid, at C16, falls right into that sweet spot.
In vitro studies have shown that Palmitic Acid is one of the fatty acids that induce rapid Malassezia growth in lab settings.
It's worth noting that what feeds yeast in a lab doesn't necessarily feed it on your face since formulation and your skin's chemistry play a bigger role.
This ingredient does have a comedogenic rating of 2, but this doesn't mean a formula with this ingredient will clog pores.
Human testing has proved that any finished product with a comedogenic ingredient won't automatically make you break out; it really comes down to concentration, formula, and your skin.
Learn more about Palmitic AcidPeg-100 Stearate is an emollient and emulsifier. As an emollient, it helps keep skin soft by trapping moisture in. On the other hand, emulsifiers help prevent oil and water from separating in a product.
PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideStearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.
In cosmetics, it is a multitasker:
Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.
Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.
This ingredient does have a comedogenic rating of 2-3, but this doesn't mean a formula with this ingredient will clog pores.
Human testing has proved that any finished product with this ingredient won't automatically make you break out; it really comes down to concentration, formula, and your skin.
Learn more about Stearic AcidWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water