What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningCyclopentasiloxane
EmollientZinc Oxide
Cosmetic ColorantTitanium Dioxide
Cosmetic ColorantHomosalate
Skin ConditioningCaprylic/Capric Triglyceride
MaskingButylene Glycol
HumectantEthylhexyl Salicylate
UV AbsorberPhenyl Trimethicone
Skin ConditioningPEG-10 Dimethicone
Skin ConditioningNiacinamide
SmoothingSynthetic Fluorphlogopite
Neopentyl Glycol
SolventLauryl PEG-10 Tris(Trimethylsiloxy)Silylethyl Dimethicone
EmulsifyingMagnesium Sulfate
Pentylene Glycol
Skin ConditioningDisteardimonium Hectorite
StabilisingTrimethylsiloxysilicate
EmollientCI 77492
Cosmetic ColorantStearic Acid
CleansingAluminum Hydroxide
EmollientTriethoxycaprylylsilane
Caprylyl Glycol
EmollientGlyceryl Caprylate
EmollientCI 77491
Cosmetic ColorantDisodium Stearoyl Glutamate
CleansingEthylhexylglycerin
Skin ConditioningAlumina
AbrasiveCI 77499
Cosmetic ColorantAdenosine
Skin ConditioningHectorite
AbsorbentLactobacillus Ferment
Skin ConditioningLactobacillus Ferment Lysate
Skin ConditioningStreptococcus Thermophilus Ferment
HumectantCollagen Extract
Skin Conditioning1,2-Hexanediol
Skin ConditioningTocopherol
AntioxidantHydrogenated Lecithin
EmulsifyingGlycine
BufferingSerine
MaskingGlutamic Acid
HumectantAspartic Acid
MaskingLeucine
Skin ConditioningAlanine
MaskingLysine
Skin ConditioningArginine
MaskingSodium Hyaluronate
HumectantHydrolyzed Elastin
EmollientTyrosine
MaskingPhenylalanine
MaskingValine
MaskingThreonine
Proline
Skin ConditioningIsoleucine
Skin ConditioningHistidine
HumectantMethionine
Skin ConditioningCysteine
AntioxidantAscorbic Acid
AntioxidantAcetyl Hexapeptide-8
HumectantTripeptide-1
Skin ConditioningAcetyl Tetrapeptide-2
Skin ConditioningPalmitoyl Tripeptide-5
Skin ConditioningCopper Tripeptide-1
Skin ConditioningPalmitoyl Tripeptide-1
Skin ConditioningPalmitoyl Pentapeptide-4
Skin ConditioningHexapeptide-9
Skin ConditioningPalmitoyl Tetrapeptide-7
Skin ConditioningPalmitoyl Hexapeptide-12
Skin ConditioningNonapeptide-1
Skin ConditioningWater, Cyclopentasiloxane, Zinc Oxide, Titanium Dioxide, Homosalate, Caprylic/Capric Triglyceride, Butylene Glycol, Ethylhexyl Salicylate, Phenyl Trimethicone, PEG-10 Dimethicone, Niacinamide, Synthetic Fluorphlogopite, Neopentyl Glycol, Lauryl PEG-10 Tris(Trimethylsiloxy)Silylethyl Dimethicone, Magnesium Sulfate, Pentylene Glycol, Disteardimonium Hectorite, Trimethylsiloxysilicate, CI 77492, Stearic Acid, Aluminum Hydroxide, Triethoxycaprylylsilane, Caprylyl Glycol, Glyceryl Caprylate, CI 77491, Disodium Stearoyl Glutamate, Ethylhexylglycerin, Alumina, CI 77499, Adenosine, Hectorite, Lactobacillus Ferment, Lactobacillus Ferment Lysate, Streptococcus Thermophilus Ferment, Collagen Extract, 1,2-Hexanediol, Tocopherol, Hydrogenated Lecithin, Glycine, Serine, Glutamic Acid, Aspartic Acid, Leucine, Alanine, Lysine, Arginine, Sodium Hyaluronate, Hydrolyzed Elastin, Tyrosine, Phenylalanine, Valine, Threonine, Proline, Isoleucine, Histidine, Methionine, Cysteine, Ascorbic Acid, Acetyl Hexapeptide-8, Tripeptide-1, Acetyl Tetrapeptide-2, Palmitoyl Tripeptide-5, Copper Tripeptide-1, Palmitoyl Tripeptide-1, Palmitoyl Pentapeptide-4, Hexapeptide-9, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Nonapeptide-1
Water
Skin ConditioningCyclopentasiloxane
EmollientZinc Oxide
Cosmetic ColorantHomosalate
Skin ConditioningEthylhexyl Salicylate
UV AbsorberCaprylyl Methicone
Skin ConditioningGlycerin
HumectantButylene Glycol Dicaprylate/Dicaprate
EmollientLauryl PEG-10 Tris(Trimethylsiloxy)Silylethyl Dimethicone
EmulsifyingTitanium Dioxide
Cosmetic ColorantButylene Glycol
HumectantNiacinamide
SmoothingDiethylamino Hydroxybenzoyl Hexyl Benzoate
UV FilterBis-Ethylhexyloxyphenol Methoxyphenyl Triazine
Skin ConditioningCollagen
MoisturisingSodium Hyaluronate
HumectantHydrogenated Lecithin
EmulsifyingLactobacillus Ferment
Skin ConditioningLactobacillus Ferment Lysate
Skin ConditioningHydrolyzed Elastin
EmollientStreptococcus Thermophilus Ferment
HumectantAdenosine
Skin ConditioningGlycine
BufferingSerine
MaskingGlutamic Acid
HumectantAspartic Acid
MaskingLeucine
Skin ConditioningAlanine
MaskingLysine
Skin ConditioningArginine
MaskingTyrosine
MaskingPhenylalanine
MaskingValine
MaskingThreonine
Proline
Skin ConditioningIsoleucine
Skin ConditioningHistidine
HumectantMethionine
Skin ConditioningCysteine
AntioxidantTocopherol
AntioxidantNonapeptide-1
Skin ConditioningAcetyl Tetrapeptide-2
Skin ConditioningAcetyl Hexapeptide-8
HumectantAscorbic Acid Polypeptide
AntioxidantCopper Tripeptide-1
Skin ConditioningTripeptide-1
Skin ConditioningPalmitoyl Tetrapeptide-7
Skin ConditioningPalmitoyl Tripeptide-1
Skin ConditioningPalmitoyl Tripeptide-5
Skin ConditioningPalmitoyl Pentapeptide-4
Skin ConditioningPalmitoyl Hexapeptide-12
Skin ConditioningHexapeptide-9
Skin ConditioningLauryl PEG-9 Polydimethylsiloxyethyl Dimethicone
Skin ConditioningMagnesium Sulfate
1,2-Hexanediol
Skin ConditioningDisteardimonium Hectorite
StabilisingMethyl Methacrylate Crosspolymer
Triethoxycaprylylsilane
Dicaprylyl Carbonate
EmollientStearic Acid
CleansingAluminum Hydroxide
EmollientGlyceryl Caprylate
EmollientCaprylyl Glycol
EmollientMica
Cosmetic ColorantEthylhexylglycerin
Skin ConditioningAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingCI 77492
Cosmetic ColorantCI 77491
Cosmetic ColorantWater, Cyclopentasiloxane, Zinc Oxide, Homosalate, Ethylhexyl Salicylate, Caprylyl Methicone, Glycerin, Butylene Glycol Dicaprylate/Dicaprate, Lauryl PEG-10 Tris(Trimethylsiloxy)Silylethyl Dimethicone, Titanium Dioxide, Butylene Glycol, Niacinamide, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Collagen, Sodium Hyaluronate, Hydrogenated Lecithin, Lactobacillus Ferment, Lactobacillus Ferment Lysate, Hydrolyzed Elastin, Streptococcus Thermophilus Ferment, Adenosine, Glycine, Serine, Glutamic Acid, Aspartic Acid, Leucine, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Valine, Threonine, Proline, Isoleucine, Histidine, Methionine, Cysteine, Tocopherol, Nonapeptide-1, Acetyl Tetrapeptide-2, Acetyl Hexapeptide-8, Ascorbic Acid Polypeptide, Copper Tripeptide-1, Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Pentapeptide-4, Palmitoyl Hexapeptide-12, Hexapeptide-9, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Magnesium Sulfate, 1,2-Hexanediol, Disteardimonium Hectorite, Methyl Methacrylate Crosspolymer, Triethoxycaprylylsilane, Dicaprylyl Carbonate, Stearic Acid, Aluminum Hydroxide, Glyceryl Caprylate, Caprylyl Glycol, Mica, Ethylhexylglycerin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, CI 77492, CI 77491
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Acetyl Hexapeptide-8, commonly known as Argireline or Acetyl Hexapeptide-3, is a popular peptide in skincare. It’s often referred to as a “Botox-like” ingredient because it helps reduce muscle movement.
By relaxing these micro-movements, Argireline may help minimize the appearance of fine lines and wrinkles. That said, it’s not as powerful as Botox, and research on its long-term effectiveness is still limited.
Beyond smoothing, Argireline may also support collagen production. Collagen is the protein that helps keep your skin firm, bouncy, and well-hydrated by strengthening the skin barrier.
So while Argireline isn’t a miracle fix, it can be a helpful addition to a routine focused on both prevention and skin health.
Read more about other common types of peptides here:
Learn more about Acetyl Hexapeptide-8This peptide is more commonly known as Thymulen 4 BG.
It is derived from a youth hormone called thymopoietin. Thymopoietin helps regulate the immune system and decreases naturally with age.
According to the manufacturer, this peptide boosts the skin's immune defenses and regenerates the outer layers of skin.
Learn more about Acetyl Tetrapeptide-2Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.
Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.
Studies have found adenosine may also help with wound healing.
In skincare products, Adenosine is usually derived from yeast.
Learn more about AdenosineAlanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin.
Aluminum Hydroxide is a form of aluminum. It can be naturally found in nature as the mineral gibbsite. In cosmetics, Aluminum Hydroxide is used as a colorant, pH adjuster, and absorbent.
As a colorant, Aluminum Hydroxide may add opacity, or reduce the transparency. Aluminum hydroxide is contains both basic and acidic properties.
According to manufacturers, this ingredient is an emollient and humectant. This means it helps hydrate the skin.
In medicine, this ingredient is used to help relieve heartburn and help heal ulcers.
There is currently no credible scientific evidence linking aluminum hydroxide in cosmetics to increased cancer risk.
Major health organizations allow the use of aluminum hydroxide in personal care products and have not flagged it as a carcinogenic risk at typical usage levels.
Learn more about Aluminum HydroxideArginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.
It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.
A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.
Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.
One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.
Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.
Learn more about ArginineAspartic Acid is an amino acid that our bodies produce naturally. It is an antioxidant.
Our body uses Aspartic Acid to help build collagen and elastin. It also plays a role in hydrating skin.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCaprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid or alcohol, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolCi 77491 is also hydrated iron III oxide. It's sole purpose is to give a red/pink hue to products.
Iron III oxides are classified as inorganic chemicals for coloring.
Synthetically created Ci 77491 is considered safer than those naturally found. This is because the synthetically created version may contain less impurities. Iron oxides are generally non-toxic and non-allergenic.
Learn more about CI 77491CI 77492 is also hydrated iron III oxide. It's sole purpose is to give a yellow hue to products.
Iron III oxides are classified as inorganic chemicals for coloring.
Synthetically created CI 77492 is considered safer than those naturally found. This is because the synthetically created version may contain less impurities. Iron oxides are generally non-toxic and non-allergenic.
Learn more about CI 77492Copper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.
It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.
While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.
Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesn’t turn soft, barely-visible facial hairs into thick, dark ones.
Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isn’t backed by large-scale studies.
Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.
For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.
After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.
While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.
Read more about other common types of peptides here:
Learn more about Copper Tripeptide-1Cyclopentasiloxane, or D5, is a silicone used to improve texture of products and trap moisture.
D5 is considered lightweight and volatile. Volatile means it evaporates quickly after application. Once evaporated, D5 leaves a thin barrier that helps keep skin hydrated.
It is also an emollient. Emollients help soften the skin and prevent water loss. Silicones create a silky texture in products. D5 helps other ingredients become more spreadable.
Studies show D5 is safe to use in skincare products. We recommend speaking with a skincare professional if you have concerns.
Learn more about CyclopentasiloxaneCysteine is an amino acid found in our bodies. It becomes an antioxidant when converted into gluthatione.
Once it becomes gluthatione, it prevents oxidative damage to parts of our cell. Gluthatione has also been shown to protect our skin from UV-B induced damage.
Disteardimonium Hectorite comes from the clay mineral named hectorite. It is used to add thickness to a product.
It can also help stabilize a product by helping to disperse other ingredients.
Hectorite is a rare, white clay mineral.
Learn more about Disteardimonium HectoriteEthylhexyl Salicylate is an organic compound used to block UV rays. It primarily absorbs UVB rays but offers a small amount of UVA protection as well.
Commonly found in sunscreens, Ethylhexyl Salicylate is created from salicylic acid and 2-ethylhexanol. You might know salicylic acid as the effective acne fighter ingredient and BHA.
The ethylhexanol in this ingredient is a fatty alcohol and helps hydrate your skin, similar to oils. It is an emollient, which means it traps moisture into the skin.
According to manufacturers, Ethylhexyl Salicylate absorbs UV wavelength of 295-315 nm, with a peak absorption at 307-310 nm. UVA rays are linked to long term skin damage, such as hyperpigmentation. UVB rays emit more energy and are capable of damaging our DNA. UVB rays cause sunburn.
Learn more about Ethylhexyl SalicylateEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinGlutamic Acid is an amino acid that is found in all living organisms. Our bodies use this to help nerve cells in the brain communicate with other cells.
In cosmetics, glutamic acid is a famous humectant. It draws water from the air to your skin, keeping your skin hydrated (like hyaluronic acid).
An in-vitro study from 2024 found glutamic acid to play a role in inhibiting inflammation and thus a potential skin-soothing ingredient.
Other studies show it to be have potential wound healing, skin barrier repair, and hair growth properties.
Glutamic acid has poor solubility in water and other solvents.
Learn more about Glutamic AcidGlyceryl Caprylate comes from glycerin and caprylic acid. It is an emollient, co-emulsifier, and preservative booster.
Its short C8 fatty acid chain makes it behave differently from its longer-chain emollient cousins like Glyceryl Stearate. It feels more lightweight, fast-absorbing, and silky instead of rich and waxy.
As a co-emulsifier, its "head" and "tail" sit at the oil-water interface. But overall, the short C8 tail and not being water soluble means it doesn't really have the muscle to emulsify a formula on its own. That's why you'll often see it paired with a primary emulsifier like Cetearyl Glucoside.
Interestingly, Glyceryl Caprylate acts as a preservative booster. This is because its fatty-acid backbone disrupts microbial lipid membranes. It shows excellent activity against bacteria and yeast but is weaker against mold.
Typical concentrations range from 0.5-1% and this ingredient is generally non-irritating.
Because this ingredient has a C8 fatty acid chain, it is outside the range that the Malassezia yeast metabolizes (making it fungal acne safe).
Learn more about Glyceryl CaprylateGlycine is the smallest amino acid and a key building block of collagen. It's part if your skin's Natural Moisturizing Factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
A study from 2022 found that an amino acid complex featuring taurine, arginine, and glycine significantly reduced skin irritation, improved redness, and accelerated the skin repair process.
Hexapeptide-9 is a signaling peptide that is made to mimic a fragment found naturally in collagen IV and XVII.
It is classified as a matrikine peptide and works by telling your skin cells (especially fibroblasts) to ramp up collagen and hyaluronic acid production.
In-vitro studies show it can enhance epidermal regeneration, boost synthesis of collagen types I, III, and IV, and improved markers of skin differentiation.
Think of skin differentiation like this: your skin cells are born at the bottom and slowly travel up to the surface as they "grow up". As they move up, they start producing specific proteins that make your skin do its job well. Two of these proteins are keratin (it makes your skin tough) and filaggrin (it breaks apart into tiny molecules to keep your skin hydrated). So Hexapeptide-9 has shown to help skin cells grow up properly and make stronger, more hydrated skin.
A manufacturer also reports increased collagen production by 117% and hyaluronic acid production by 267%.
Just know much of the published data comes from manufacturer-sponsored studies. There is a recent clinical trial showing promising anti-aging results but the evidence base is still growing.
Generally, this ingredient is well-tolerated and there's no harm in using it as a supportive ingredient in your routine.
Learn more about Hexapeptide-9Histidine is a semi-essential amino acid used by our bodies to create protein. It has humectant and skin conditioning properties.
Our bodies use histidine to create filaggrin - filaggrin is a structural protein that the skin uses in maintaining skin barrier.
One study found histidine and carnosine to be a dynamic duo for your skin:
Oral histidine has also been found to help with filaggrin-deficit skin disorders such as atopic dermatitis.
Why is it considered a semi-essential amino acid? This is because adults are able to create it but children must get it from their diet.
Learn more about HistidineHomosalate is a chemical sunscreen filter that provides protection in the UV-B range (280nm - 320 nm), with a peak protection at 306 nm. It is internationally approved for use in sunscreens.
Homosalate is not photo-stable, meaning it's strength as a UV filter degrades over time with exposure to the sun. Because of this, it's often used in combination with other chemical sunscreen filters as avobenzone (which protects from the UV-A range). Homosalate also helps act as a solvent for harder-to-dissolve UV filters.
(Part of the reason that sunscreens need to be frequently re-applied is due to the photo instability of many chemical sunscreen filters)
Currently, homosalate is approved in concentrations up to 10% in the EU and 15% in the US. The FDA is currently doing further research on the effects of homosalate, and it is possible that these approved concentrations will change in the future.
Learn more about HomosalateHydrogenated Lecithin is a more stable version of lecithin.
It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.
This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.
Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.
A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).
Learn more about Hydrogenated LecithinWe don't have a description for Hydrolyzed Elastin yet.
Isoleucine is an amino acid that helps reinforce our skin barrier. This amino acid plays a role in creating protein for the body.
Fun fact: Isoleucine is found in meat, fish, dairy, legumes, and nuts.
This ingredient is made when the Lactobacillus bacteria (the same kind that makes yogurt and kimchi) are allowed to ferment a nutrient medium.
As it ferments, it collects lactic acid, peptides, enzymes, and other bioactive metabolites to provide:
A 2023 review noted that probiotic fermentation ingredients like this one can enhance antioxidant capacity, reduce UV-induced oxidative damage, and support barrier function.
One clinical study from the same year showed a Lactobacillus ferment lysate significantly reduced transepidermal water loss and improved skin hydration.
Another review highlighted that topical Lactobacillus-based preparations can improve ceramide levels in the stratum corneum, support barrier integrity, and even help reduce S. aureus colonization in atopic dermatitis.
Why is this so cool?
Basically, your skin's outer layer works as a brick wall; skin cells are bricks and ceramides are the mortar holding it together. Moisture escapes, irritants get in, and your skin gets dry and reactive when ceramide levels drop. On top of that, "bad" skin bacteria S. aureus loves to move in when your barrier is weak to make inflammation and irritation worse.
So Lactobacillus ferment is basically patching the wall and evicting the troublemaker when it boosts ceramide production and help keep S. aureus in check.
On top of all this, it also acts as a mild antimicrobial preservative booster.
Just so you know, most studies focus on specific strains or the lysate form rather than this generic "Lactobacillus Ferment", so results can vary.
Though it's a promising ingredient, it doesn't have decades of robust clinical data behind it just yet.
Lactobacillus Ferment is generally considered safe for fungal-acne prone skin. The key thing to understand is that it comes from bacteria, not yeast or fungus.
Yeast-derived ferments (like galactomyces) have been shown to activate a protein that's linked to Malassezia-related skin issues whereas lactobacillus doesn't have that problem.
Its byproducts also don't contain the types of fatty acids (C11-24 chain lengths) that Malassezia feeds on.
Learn more about Lactobacillus FermentLactobacillus Ferment Lysate is a postbiotic with skin soothing properties. Postbiotics are inactive molecules produced by probiotic bacteria that provide skin benefits.
This ingredient comes from the secretion of the bacteria, Lactobacillus.
Studies show this ingredient can help calm redness and may help treat the signs of photoaging; however, the evidence is inconclusive and further studies are needed.
Lactobacillus Ferment is generally considered safe for fungal-acne prone skin. The key thing to understand is that it comes from bacteria, not yeast or fungus.
Yeast-derived ferments (like galactomyces) have been shown to activate a protein that's linked to Malassezia-related skin issues whereas lactobacillus doesn't have that problem.
Its byproducts also don't contain the types of fatty acids (C11-24 chain lengths) that Malassezia feeds on.
Learn more about Lactobacillus Ferment LysateLauryl PEG-10 Tris(Trimethylsiloxy)Silylethyl Dimethicone is a type of silicone.
We don't have a description for Leucine yet.
Lysine is an essential amino acid (your body cannot make it on its own). It has skin conditioning properties and one of the key players in collagen synthesis.
When your body creates collagen, lysine is basically the glue that holds everything together. It helps collagen fibers lock into each other and stay strong, with vitamin C being its trusty sidekick. Without enough lysine, this glue gets flimsy and less firm, resulting in less bouncy skin.
In skincare, lysine is mostly there to help keep your skin moisturized. It carries water through your skin's layers so everything stays plump.
So will putting lysine on your face create bouncier skin?
It's hard to say; most of the exciting collagen research on lysine comes from oral supplements or lab studies on mice. Further research is needed to truly understand what role topical lysine plays in skincare and your skin.
However, there's no harm in adding lysine to your routine as a supportive and hydrating ingredient.
Learn more about LysineMagnesium Sulfate is a salt. More specifically, it is an epsom salt, or the bath salt used to help relieve muscle aches.
Despite having ‘sulfate’ in the name, it isn’t a surfactant or cleansing agent like sodium lauryl sulfate. Unlike those sulfates, magnesium sulfate doesn’t have the same cleansing or foaming properties (it's simply a type of salt).
In cosmetics, Magnesium Sulfate is used to thicken a product or help dilute other solids. It is a non-reactive and non-irritating ingredient.
One study shows magnesium deficiency may lead to inflammation of the skin. Applying magnesium topically may help reduce inflammation.
You can find this ingredient in sea water or mineral deposits.
Learn more about Magnesium SulfateMethionine is an essential amino acid. It is a conditioning agent and commonly found in both skin and hair products.
This amino acid is a precursor to glutathione, a powerful antioxidant.
Fun fact: Methionine can be found in meat, fish, and dairy. It cannot be naturally produce and requires dietary intake.
Learn more about MethionineNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideNonapeptide-1 is created from amino acids including arginine and lysine.
It has antioxidant and antimicrobial properties.
Emerging studies show Nonapeptide-1 to help with reducing pigmentation and brightening the skin. It has shown to prevent the activation of tyrosinase, an enzyme in the skin that begins the process of melanin creation. Melanin is responsible for giving skin a tan or dark spots.
Learn more about Nonapeptide-1Palmitoyl Hexapeptide-12 is a synthetic lipopeptide. This just means it's a short chain of six amino acids with a palmitic acid molecule attached to one end.
The palmitoyl group increases the lipophilicity, helping it penetrate the lipid-rich outer layer of skin more effectively.
Once inside, it helps with keeping skin springy and firm. It works by mimicking the skin repair signals your skin naturally sends out when it's damaged and telling it to kick into rebuild mode.
Studies have shown it can help strengthen the skin barrier as well so it's useful beyond just anti-aging.
In vitro studies suggest it can switch on genes that help skin cells grow, move around, and rebuild skin structure. Just keep in mind most of the strong evidence is from lab studies rather than large-scale clinical trials.
Lab studies suggest it can switch on genes that help skin cells grow, move around, and rebuild skin structure.
This ingredient is usually used at very low concentrations (0.002% in leave-on products).
Fungal acne note:
Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.
You might know this ingredient as Matrixyl. It is a synthetic peptide made up of five amino acids attached to a palmitic acid, a fatty acid that helps it absorb into skin more easily.
As a signal peptide, Matrixyl acts like a little messenger. Once it reaches your skin cells, it tells them to ramp up production of collagen, elastin, and other proteins that keep skin looking firm and smooth.
A 12 week clinical study found that a moisturizer containing just 3 ppm of Matrixyl led to a significant improvement in fine-lines and wrinkles. Another study showed an 18% reduction in wrinkle depth, 37% reduction in wrinkle thickness, and a 21% improvement in skin firmness after just 28 days of twice-daily use.
The coolest part is that it works at incredibly low concentrations (like 0.0003%) and it plays well with other actives.
The CIR (Cosmetic Ingredient Review) panel found it to be non-sensitizing across multiple tests and human patch tests also showed no irritation or sensitization.
Fun fact: Matrixyl was originally developed by French company Sederma and Procter & Gamble.
Read more about other common types of peptides here:
Learn more about Palmitoyl Pentapeptide-4Palmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a synthetic peptide. Its main job is to fight what researchers call "inflammaging".
"Inflammaging" is the slow, low-grade chronic inflammation that quietly breaks down collagen as we age.
This ingredient calms down a specific inflammation signal in your skin cells (called IL-6). When left unchecked, this signal triggers enzymes that break down collagen and elastin.
Clinical testing showed statistically significant improvements in:
Studies also found the more of this ingredient used, the more your skin produces Collagen I, fibronectin, and hyaluronic acid.
You'll likely see this ingredient paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.
A 3% concentration applied twice daily for two months showed meaningful skin rejuvenation results in clinical panels.
Fungal acne note:
Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.
Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.
That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.
Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.
In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.
Human clinical data is promising, but modest:
A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.
A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.
You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.
Fungal acne note:
Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.
Palmitoyl Tripeptide-5 is a synthetic signal lipopeptide. This just means it is a three amino acid chain bolted onto a palmitic acid tail so it can slip through the skin's lipid barrier.
This peptide has a "build more, lose less" approach.
It's designed to mimic the collagen-stimulating activity in your skin by copying a snippet of one of your skin's own matrix proteins. This nudges fibroblasts into making more collagen while inhibiting the enzyme that breaks down skin protein.
The manufacturer's in vivo study of 45 volunteers found 1% and 2.5% reduced the appearance of wrinkles by 7% and 12% respectively, after using it twice daily for 84 days.
This is in the expected range for peptides; they're slow and cumulative actives and not overnight fixers.
Typical use levels range from 1-3% and this ingredient gets along with pretty much everything.
On the fungal acne front:
Although palmitic acid sits in the chain length that Malassezia can feed on, this ingredient has it locked in an amine bond. This makes it hard for Malassezia to access as a source of food, and therefore fungal acne safe.
Phenylalanine is an amino acid. It is a skin soothing and hydrating ingredient. Amino acids play a crucial role in wound healing and skin hydration.
This ingredient is also used to help even out skin tone due to its ability to disrupt the melanin production process.
Two structures of phenylalanine exist: L-phenylalanine and D-phenylalanine. L-phenylalanine is essential, this means our bodies cannot produce it naturally and we must get it from foods. Our bodies convert D-phenylalanine to neurotransmitters, and D-phenylalanine is found in our bodies naturally.
Some foods that contain L-phenylalanine include eggs, soybeans, beef, milk.
Learn more about PhenylalanineProline is a non-essential amino acid, meaning your body can make it on its own. In skincare, it is a skin conditioning ingredient that keeps skin soft and hydrated.
It makes up about 23% of the collagen molecule (collagen is the protein responsible for keeping your skin firm) and is involved in your skin's natural hyaluronic acid production. When applied topically, proline can penetrate the skin fairly well due to its small molecular size.
Reviews of this ingredient have found it to be neither a dermal irritant nor a sensitizer.
Fun fact: Proline can be found in protein-rich foods like meat, fish, eggs, and dairy.
Learn more about ProlineSerine is a non-essential amino acid (your body makes it on its own!). It is a major player in your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Serine is one of your NMF's most abundant components that works as a skin-identical humectant. Its hydroxyl group grabs onto water molecules to boost hydration without any heaviness or occlusion.
Research on a hydrogel with serine confirmed this serine got delivered to your stratum corneum and demonstrated enhanced skin moisturization.
Interestingly serine also helps your skin produce filaggrin, a protein that keeps your skin barrier strong and used to create collagen.
Learn more about SerineSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateStearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.
In cosmetics, it is a multitasker:
Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.
Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.
Learn more about Stearic AcidStreptococcus Thermophilus Ferment is created by fermenting Streptococcus thermophilus, the same lactic acid bacteria used to make yogurt. It has humectant and skin conditioning properties.
A study from 2003 found that applying a cream containing this ingredient to human skin significantly increased ceramide levels in the stratum corneum in just 7 days. This result applied to both healthy volunteers and those with atopic dermatitis.
Ceramides are the lipids that hold your skin barrier together so they play a role in moisture retention and contribute to a stronger barrier.
The cream also improved scaling and itchiness for the group with atopic dermatitis.
How does Streptococcus Thermophilus Ferment work? Your skin naturally contains a fatty substance called sphingomyelin. S. thermophilus comes packed with enzymes that snip the sphingomyelin apart and turn it into ceramides.
So it's not adding ceramides from the outside but helping your skin make more of its own.
On top of that, a 2022 lab study found that S. thermophilus extract could calm down the overactive scarring process in skin cells. It tells cells to chill out instead of producing excess scar tissue. There's also some early stage research that hints at possible wound healing perks as well.
Last but not least, the type of ceramides that S. thermophilus creates (phytosphingosine), also happens to fight the bacteria that causes breakouts.
This ingredient is generally considered fungal acne safe because it is a bacteria and not a yeast/fungus.
The ferments that raise concerns for Malassezia-prone skin are typically yeast-derived ones because they have been shown to activate a protein that's linked to Malassezia-related skin issues whereas lactobacillus doesn't have that problem.
There's no published evidence suggesting S. thermophilus promotes Malassezia growth.
Learn more about Streptococcus Thermophilus FermentThreonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.
Our skin uses threonine for creating collagen and elastin. Humans are not able to create threonine and must get it through eating foods such as fish, lentils, poultry, sesame seeds, and more.
Titanium dioxide is a mineral UV filter widely used in sunscreens and cosmetics.
It is one of only two UV filters officially classified as “mineral” by regulatory agencies, the other being zinc oxide.
Titanium dioxide provides broad-spectrum protection mostly in the UVB and UVAII range, with some protection in the UVAI range.
While its UVA protection isn’t as strong as zinc oxide’s, the difference is minor.
A common myth is that mineral UV filters reflect UV light. However, modern research shows titanium dioxide absorbs UV radiation like chemical filters (~95% absorption & 5% reflection).
Thanks to its non-irritating nature, titanium dioxide is suitable for sensitive, acne-prone, or redness-prone skin. It is unlikely to cause "eye sting" like other sunscreen ingredients.
A major drawback of this ingredient is its white cast and thick texture. This is why mineral sunscreens often leave a white cast and are less cosmetically elegant than chemical/hybrid sunscreens.
To improve white cast and spreadability, micronized or nano-sized titanium dioxide is often used.
There are ongoing concerns surrounding nano-titanium oxide's impact on marine ecosystems.
There is no conclusive evidence that any form of titanium oxide (or any other sunscreen ingredients) will cause harm to marine ecosystems or coral reefs. The science is still developing but many consumers are keeping a close eye on this issue.
Please note, many destinations have reef-safety sunscreen rules. For instance, the U.S. Virgin Islands advises all visitors to use non-nano mineral sunscreens.
Nano mineral sunscreens once raised safety concerns about absorption into skin.
Extensive research has shown that they do not penetrate healthy or damaged skin; they remain safely on the surface and the top layer of dead skin (stratum corneum).
You'll likely find titanium dioxide bundled with alumina, silica, or dimethicone. These ingredients help make titanium dioxide highly photostable; this prevents it from interacting with other formula components under UV light.
Learn more about Titanium DioxideTocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Learn more about TocopherolTriethoxycaprylylsilane is a silicon-based surface modifier that makes sunscreens feel silky and makeup stay put.
Its main job is to coat mineral particles like titanium dioxide, zinc oxide, and color pigments in a thin, oily layer so they spread smoothly, don't clump, and stick to skin better.
This ingredient is typically used at low levels (up to 2.5% in eyeshadow and 1% in lipstick).
Learn more about TriethoxycaprylylsilaneTripeptide-1, also known as GHK), is a small, three-amino-acid peptide made up of glycine, histidine, and lysine.
This ingredient is a signal peptide and tell your skin to start producing fresh collagen, elastin, and other key structural proteins. This helps maintain firmness and reduces the look of fine-lines/wrinkles.
GHK is also unique because is also acts as a carrier peptide. It binds to and transports copper ions (forming the complex GHK-Cu). This form has been studied for decades and is known to stimulate wound healing, boost antioxidant defenses, and promote collagen/elastin synthesis.
In-vitro studies show both GHK and GHK-CU increase fibroblast activity that enhances the production of collagen, elastin, fibronectin, and other extracellular matrix components.
Both of these compounds also help balance enzymes that control collagen breakdown.
Human studies (in-vivo) using GHK-Cu creams have reported visible improvements to skin density, elasticity, and wrinkle depth after several weeks of use.
A small clinical study also found topical collagen tripeptide improved wrinkle appearance and skin elasticity in women after four weeks.
While these results are promising, most research is based on GHK-Cu or its derivatives rather than Tripeptide-1 alone (Palmitoyl Tripeptide-1 is a famous derivative of GHK). However, the consensus still supports GHK as a potent skin-signaling molecule that can encourage regeneration and maintain youthful looking skin.
Fun fact: GHK is a naturally occurring fragment of type 1 collagen that can be found in human plasma, saliva, and urine.
Learn more about Tripeptide-1Tyrosine is one of the amino acids used to create protein. It plays a role in melanin production.
A study from 2012 found tyrosine to show promising results in restoring skin volume.
Valine is an essential amino acid. It is used by our bodies for tissue repair and muscle growth.
An essential amino acid is one in which our bodies cannot naturally produce so we must get them through diet. Foods such as eggs, dairy, red meat, and fish contain valine.
This ingredient can either be derived from an animal product or be synthetically created.
Learn more about ValineWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterZinc Oxide is a mineral broad-spectrum UV filter; it is the broadest UVA and UVB reflector approved by the FDA. It also has skin protectant and skin soothing properties.
Zinc oxide is one of the most effective broad-spectrum UV filters. It protects against UVB, UVAII, and UVAI. In comparison to its counterpart titanium dioxide, zinc oxide provides uniform and extended UVA protection.
Another great benefit? This ingredient is highly photostable so it won't degrade easily under sunlight.
A common myth is that mineral UV filters are widely believed to primarily reflect UV light.
However, modern research shows titanium dioxide absorbs UV radiation like chemical filters (~95% absorption & 5% reflection).
Zinc oxide has great skin soothing properties so you'll likely find this in sunscreens formulated for sensitive skin or babies/children. It is unlikely to cause "eye sting" like other sunscreen ingredients.
Regulatory agencies consider zinc oxide to be non-toxic and safe. It has also been shown to not penetrate the skin.
Unfortunately, this ingredient does leave a visible white cast. This is why mineral sunscreens are often less cosmetically elegant than chemical or hybrid ones.
In cosmetics, zinc oxide can be found in both non-nano and nano-sized forms. The nano version is used to reduce white cast and improve the texture of sunscreen formulas.
There are ongoing concerns surrounding nano-zinc oxide's impact on marine ecosystems and whether it can be absorbed into skin.
Regarding marine ecosystems and coral reefs, there is no conclusive evidence that any form of zinc oxide (or any other sunscreen ingredients) will cause harm. The science is still developing but many consumers are keeping a close eye on this issue.
Please note, many destinations have reef-safety sunscreen rules. For instance, the U.S. Virgin Islands advises all visitors to use non-nano mineral sunscreens.
There has also been some stir about whether micronized or nano zinc oxide has potential photoxicity and absorption through the skin/lungs.
An in-vitro (done in a test tube or petri dish) study demonstrated micronized zinc oxide to have potential phototoxicity. There's no need to fret; the EU Commission's Scientific Committee on Consumer Safety has stated, "The relevance of these findings needs to be clarified by appropriate investigations in vivo." Or in other words, further studies done on living organisms are needed to prove this.
Current research shows zinc oxide nanoparticles do not penetrate intact or sunburned skin. They either remain on the surface or in the outermost layer of dead skin (stratum corneum).
Zinc oxide is one of only two classified mineral UV filters with titanium dioxide being the other one.
Fun fact: Zinc has been used throughout history as an ingredient in paint and medicine. An Indian text from 500BC is believed to list zinc oxide as a salve for open wound. The Ancient Greek physician Dioscorides has also mentioned the use of zinc as an ointment in 1AD.
Learn more about Zinc Oxide