Anua Niacinamide 10% + TXA 4% Dark Spot Correcting Serum Versus Curology Custom Rx (0.02% Tretinoin, 5% Azelaic Acid, 4% Niacinamide)
Updated on January 09, 2025
Overview
What they are
These products are both cruelty-free and reef safe . They have a total of 3 ingredients in common
Cool Features
They both contain niacinamide
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any harsh alcohols, common allergens, parabens, silicones or sulfates
What's Inside
They both contain fragrances
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Anua Niacinamide 10% + TXA 4% Dark Spot Correcting Serum 51 ingredients
Curology Custom Rx (0.02% Tretinoin, 5% Azelaic Acid, 4% Niacinamide) 14 ingredients
About this product
About this product
At a glance
Click on any of the items below to learn more
Anua Niacinamide 10% + TXA 4% Dark Spot Correcting Serum 51 ingredients
Curology Custom Rx (0.02% Tretinoin, 5% Azelaic Acid, 4% Niacinamide) 14 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterNiacinamide has emerged as an all-star ingredient due to its many benefits.
It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.
Other benefits include smoothing wrinkles and minimizing redness.
The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.
Learn more about NiacinamideThis ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.
Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.
Learn more about Caprylic/Capric TriglycerideIngredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Anua Niacinamide 10% + TXA 4% Dark Spot Correcting Serum 51 ingredients
Curology Custom Rx (0.02% Tretinoin, 5% Azelaic Acid, 4% Niacinamide) 14 ingredients

Reviews
Here's what our community thinks
Anua Niacinamide 10% + TXA 4% Dark Spot Correcting Serum 51 ingredients
I'm very pleased with the results of this product. Within 2 weeks, it was able to remove most of the stubborn dark spots/scaring that was on my temple area. Despite having fragrance in the formulation, I actually didn't notice any irritation or breaking out after using it. It's nice that the product isn't too expensive either (Roughly $20 on Amazon when I purchased at the time) I also find the Show more
I’ve been using this for three months now on sensitive and reactive skin. I had no bad response, no irritation or breaking out. I use it both morning and night, and I believe some results are there - dark marks are slowly fading, and any spots I’ve had while using this leave less of a dark mark than they used to.
Between this and skin1004 tone brightening capsule serum, I think this has had Show more