Judydoll Stay Shine Lipstick
A lipstick with 52 ingredients, including exfoliants, vitamin E, and hyaluronic acid.
Overview
What it is
Lipstick with 52 ingredients that contains exfoliants, hyaluronic acid, peptides and Vitamin E
Cool Features
It is reef safe
Suited For
It has ingredients that are good for anti aging, dry skin, brightening skin, sensitive skin, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, parabens or sulfates
Fun facts
Judydoll is from China.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Trimethyl Pentaphenyl Trisiloxane
EmollientVp/Hexadecene Copolymer
Hydrogenated Polydecene
EmollientHydrogenated Polycyclopentadiene
Polybutene
Hydrogenated Coco-Glycerides
EmollientOctyldodecanol
EmollientPolyethylene
AbrasiveSynthetic Wax
AbrasiveDiphenylsiloxy Phenyl Trimethicone
Skin ConditioningDiisostearyl Malate
EmollientOryza Sativa Bran Wax
Skin ConditioningMicrocrystalline Wax
Emulsion StabilisingCI 77891
Cosmetic ColorantPolyglyceryl-2 Triisostearate
EmulsifyingEuphorbia Cerifera Cera
AstringentSucrose Tetrastearate Triacetate
EmollientHydrogenated Poly(C6-14 Olefin)
EmollientCI 77492
Cosmetic ColorantGlyceryl Caprylate
EmollientOctanediol
CI 15850
Cosmetic ColorantCI 19140
Cosmetic ColorantDextrin Palmitate
EmulsifyingCetyl PEG/PPG-10/1 Dimethicone
EmulsifyingPolyglyceryl-2 Diisostearate
EmulsifyingCI 77499
Cosmetic ColorantCI 77491
Cosmetic ColorantRosa Damascena Flower Oil
MaskingCI 42090
Cosmetic ColorantTocopherol
AntioxidantBHT
AntioxidantCaprylic/Capric Triglyceride
MaskingCollagen
MoisturisingWater
Skin ConditioningPentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
AntioxidantRicinus Communis Seed Oil
MaskingEthylhexyl Palmitate
EmollientButylene Glycol
HumectantMannose
HumectantSodium Hyaluronate
HumectantHydrogenated Castor Oil
EmollientPentylene Glycol
Skin ConditioningPEG-60 Sorbitan Tetrastearate
EmulsifyingRosa Rugosa Flower Extract
Skin ConditioningMyrothamnus Flabellifolia Leaf/Stem Extract
HumectantGlucose
HumectantVinegar
Rosa Hybrid Flower Extract
Skin ConditioningPunica Granatum Fruit Extract
AntioxidantSodium Dna
Skin ConditioningPalmitoyl Tripeptide-1
Skin ConditioningTrimethyl Pentaphenyl Trisiloxane, Vp/Hexadecene Copolymer, Hydrogenated Polydecene, Hydrogenated Polycyclopentadiene, Polybutene, Hydrogenated Coco-Glycerides, Octyldodecanol, Polyethylene, Synthetic Wax, Diphenylsiloxy Phenyl Trimethicone, Diisostearyl Malate, Oryza Sativa Bran Wax, Microcrystalline Wax, CI 77891, Polyglyceryl-2 Triisostearate, Euphorbia Cerifera Cera, Sucrose Tetrastearate Triacetate, Hydrogenated Poly(C6-14 Olefin), CI 77492, Glyceryl Caprylate, Octanediol, CI 15850, CI 19140, Dextrin Palmitate, Cetyl PEG/PPG-10/1 Dimethicone, Polyglyceryl-2 Diisostearate, CI 77499, CI 77491, Rosa Damascena Flower Oil, CI 42090, Tocopherol, BHT, Caprylic/Capric Triglyceride, Collagen, Water, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Ricinus Communis Seed Oil, Ethylhexyl Palmitate, Butylene Glycol, Mannose, Sodium Hyaluronate, Hydrogenated Castor Oil, Pentylene Glycol, PEG-60 Sorbitan Tetrastearate, Rosa Rugosa Flower Extract, Myrothamnus Flabellifolia Leaf/Stem Extract, Glucose, Vinegar, Rosa Hybrid Flower Extract, Punica Granatum Fruit Extract, Sodium Dna, Palmitoyl Tripeptide-1
Key Ingredients
Benefits
Concerns
Ingredients Explained
Trimethyl Pentaphenyl Trisiloxane is a type of silicone.
VP/Hexadecene Copolymer is a synthetic film-forming agent. It has both water and oil loving properties, allowing it to create a flexible, even film on the skin.
This ingredient helps enhance texture, smoothness, and wear resistance in makeup products while reducing tackiness.
Hydrogenated Polydecene is a synthetic emollient. It forms a non-occlusive film on the skin's surface to provide a silky feel without being greasy.
In vivo studies in volunteers with atopic and dry skin showed no irritation or intolerance. The volunteers also saw a positive effect in dryness, scaling, and roughness after 28 days of use.
Concentrations up to 100% in guinea pig tests found it to be non-sensitizing and completely safe for use in cosmetics.
Learn more about Hydrogenated PolydeceneWe don't have a description for Hydrogenated Polycyclopentadiene yet.
Polybutene is used to help control the viscosity of a product. This just means it helps adjusts the texture.
It is a polymer and does not get absorbed into the skin due to its large size.
Studies found this ingredient did not irritate skin in concentrations below 15%.
Learn more about PolybuteneHydrogenated Coco-Glycerides isn't fungal acne safe.
Octyldodecanol is a fatty alcohol sourced from plant oils like coconut or palm (or made synthetically).
It is:
You'll likely see this in many BHA products because this is the go-to solvent for salicylic acid.
This ingredient is typically used at levels between 2-20%.
Regarding fungal acne:
In 2019, this ingredient was tested against multiple Malassezia species (the yeast that causes fungal acne) and showed no growth.
Polyethylene is a synthetic ingredient that helps the skin retain moisture. It is a polymer.
It is also typically used within product formulations to help bind solid ingredients together and thicken oil-based ingredients. When added to balms and emulsions, it helps increase the melting point temperature.
Synthetic Wax is a manufactured hydrocarbon wax. In formulas, it works as an occlusive emollient that helps reduce water loss and improves the spreadability of products.
Research comparing synthetic wax to traditional mineral-derived products found that formulas containing it perform as well for skin hydration.
It is considered non-comedogenic and vegan-friendly.
This ingredient has a well-established safety record by the CIR Expert Panel for Cosmetic Ingredient Safety.
Synthetic Waxes are straight/branched-chain hydrocarbons with no ester bond or fatty acids. That means there is nothing for the Malassezia yeast to feed on.
Learn more about Synthetic WaxDiphenylsiloxy Phenyl Trimethicone is a silicone. It has a high refractive index and adds shine to formulations.
According to the safety review by the Cosmetic Ingredient Review (CIR) Expert Panel, it is safe for use in cosmetics under the current practices and concentrations.
Diisostearyl Malate is an emollient and most often used in lip products. It comes from isostearyl alcohol, a fatty acid, and malic acid, an AHA.
As an emollient, Diisostearyl Malate helps create a thin film on your skin to trap moisture in. This helps keep your skin soft and smooth.
Oryza Sativa Bran Wax is wax from the outer layer of a rice kernel. It has moisturizing properties due to its polysaccharides and omega-3 fatty acids content.
This ingredient is a byproduct of milling rice, or the operation to produce a whole grain rice product.
Microcrystalline Wax is derived from petroleum through a de-oiling process, then highly refined and purified before use in cosmetics.
In skincare formulations, it is used to improve texture and create a smooth, even consistency. It also helps stabilize products by preventing ingredients from separating.
Ci 77891 is a white pigment from Titanium dioxide. It is naturally found in minerals such as rutile and ilmenite.
It's main function is to add a white color to cosmetics. It can also be mixed with other colors to create different shades.
Ci 77891 is commonly found in sunscreens due to its ability to block UV rays.
Learn more about CI 77891Polyglyceryl-2 Triisostearate is a plant-derived emulsifier and pigment-dispersing agent with a non-sticky skin feel.
It helps products glide on smoothly and prevents oil and water from separating in a formula, making it suitable for sunscreen and makeup formulations.
The EU inventory of cosmetics has no use restrictions on this ingredient and it is considered well-tolerated.
This ingredient may not be fungal acne safe because it is derived from isostearic acid.
Learn more about Polyglyceryl-2 TriisostearateEuphorbia Cerifera Cera (aka candelilla wax) is a vegan stand-in for beeswax. It is a plant-derived wax that functions as an astringent, emulsion stabilizer, film-former, and skin conditioner.
On skin, it forms a protective barrier that helps lock in moisture while it enhances product stability, prevents separation, and helps color last longer in makeup.
This ingredient is generally safe for use in cosmetics with one nuance: some grades of candelilla wax can naturally contain benzyl alcohol at concentrations high enough to require declaration under EU labeling rules. This isn't a concern for most people but relevant for those with fragrance sensitivities.
Candelilla wax contains fatty acids (mainly C31) and wax esters that can be used by the Malassezia yeast, so this ingredient may not be fungal acne safe.
You might see Euphorbia Cerifera "Wax" instead of "cera". This is because some brands, databases, or labels use it interchangeably; they're the same ingredient.
Learn more about Euphorbia Cerifera CeraSucrose Tetrastearate Triacetate isn't fungal acne safe.
This ingredient is a synthetic ingredient with emollient and skin conditioner used to make skincare products feel more lightweight on the skin. It helps improve slip and spreadability without feeling greasy.
Because it is high molecular weight and lipophilic (oil loving), it remains on the surface of skin.
CI 77492 is also hydrated iron III oxide. It's sole purpose is to give a yellow hue to products.
Iron III oxides are classified as inorganic chemicals for coloring.
Synthetically created CI 77492 is considered safer than those naturally found. This is because the synthetically created version may contain less impurities. Iron oxides are generally non-toxic and non-allergenic.
Learn more about CI 77492Glyceryl Caprylate comes from glycerin and caprylic acid. It is an emollient, co-emulsifier, and preservative booster.
Its short C8 fatty acid chain makes it behave differently from its longer-chain emollient cousins like Glyceryl Stearate. It feels more lightweight, fast-absorbing, and silky instead of rich and waxy.
As a co-emulsifier, its "head" and "tail" sit at the oil-water interface. But overall, the short C8 tail and not being water soluble means it doesn't really have the muscle to emulsify a formula on its own. That's why you'll often see it paired with a primary emulsifier like Cetearyl Glucoside.
Interestingly, Glyceryl Caprylate acts as a preservative booster. This is because its fatty-acid backbone disrupts microbial lipid membranes. It shows excellent activity against bacteria and yeast but is weaker against mold.
Typical concentrations range from 0.5-1% and this ingredient is generally non-irritating.
Because this ingredient has a C8 fatty acid chain, it is outside the range that the Malassezia yeast metabolizes (making it fungal acne safe).
Learn more about Glyceryl CaprylateWe don't have a description for Octanediol yet.
Ci 15850 is the pigment color red. It is an azo dye and created synthetically.
Azo dyes need to be thoroughly purified before use. This allows them to be more stable and longer-lasting.
This ingredient is common in foundations, lipsticks, and blushes. This color is described as brown/orangey red.
It has many secondary names such as Red 6 and Red 7. According to a manufacturer, Red 6 usually contains aluminum.
Learn more about CI 15850CI 19140 is also known as Tartrazine. Tartrazine is a synthetic dye used in cosmetics, foods, and medicine to add a yellow color.
Tartrazine is created from petroleum and is water-soluble.
Some people may experience allergies from this dye, especially asthmatics and those with an aspirin intolerance.
Learn more about CI 19140Dextrin Palmitate is an oil-loving texture helper made by bonding palmitic acid onto Dextrin. It's main roles are to turn liquid oils into spreadable gels and prevent ingredients from separating.
It also lends a silky, non-greasy slip that makes products feel more elegant.
Typical use concentrations range from 0.5-5%, but can go up to 10% depending on how firm the gel is.
Because it's an ester built on a fatty acid, it may not be fungal acne safe.
Learn more about Dextrin PalmitateThis ingredient is a silicone-based emulsifer that helps the water and oil phases play nicely together.
It's pretty effective because one end of the molecule loves oil and the other one loves water.
Besides holding formulas together, it also leaves a silky and lightweight feel on skin without the greasiness. A manufacturer also claims it can help with the controlled release of active ingredients.
The CIR Expert Panel found this ingredient to not be sensitizing in concentrations up to 15% in human maximazation testing and dimethicone-based compounds were not comedogenic.
It has a high molecular weight well above 1,000 g/mol which means it limits meaningful skin penetration.
A 2019 study specifically tested this ingredient and found no observable Malassezia growth in its presence.
Learn more about Cetyl PEG/PPG-10/1 DimethiconePolyglyceryl-2 Diisostearate isn't fungal acne safe.
Ci 77499 is also hydrated iron III oxide. It is created from mixing red and black iron oxides. This helps give shades of darkness to a product.
Iron III oxides are classified as inorganic chemicals for coloring.
Ci 77491 is also hydrated iron III oxide. It's sole purpose is to give a red/pink hue to products.
Iron III oxides are classified as inorganic chemicals for coloring.
Synthetically created Ci 77491 is considered safer than those naturally found. This is because the synthetically created version may contain less impurities. Iron oxides are generally non-toxic and non-allergenic.
Learn more about CI 77491Rosa Damascena Flower Oil is an essential oil made from the Damask Rose. It is often used as a fragrance in cosmetics.
Rose Oil has antibacterial and antioxidant properties due to its terpene, glycoside, flavonoid, anthocyanin, and Vitamin C content.
Other major parts of Rose Oil include citronellol and geraniol. Both of these are known EU allergens and cause contact-allergies.
The downsides of this ingredient outweight the positives.
Learn more about Rosa Damascena Flower OilCi 42090 is a synthetic dye created from petroleum. It is used to give a bright blue color to cosmetics, medicine, and food.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Learn more about TocopherolBHT is a synthetic antioxidant and preservative.
As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.
As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.
The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.
However, it was recently restricted for use in the UK as of April 2024.
Learn more about BHTCaprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Learn more about Caprylic/Capric TriglycerideCollagen is a big structural protein that your body uses to keep skin firm and bouncy. Despite the marketing, topically applied collagen doesn't "refill" the collagen in your skin.
The molecule is too big to pass through your skin barrier so intact Collagen physically can't get past the surface.
What it actually does in your skincare is work as a humectant and film-former: it binds water, lays down a light moisturizing film, and reduces water loss from the surface. This helps make skin feel smoother and temporarily plumper.
This ingredient has been found safe for use in cosmetics with clinical studies showing no irritation, sensitization, or phototoxicity. It's typically used at low concentrations (often a fraction of a percent up to a few percent).
Collagen will not increase sun sensitivity, but you should always wear sunscreen during the day.
Learn more about hydrolyzed collagen or soluble collagen.
Learn more about CollagenWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterPentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate (long name, huh?) is a synthetic antioxidant.
It is used to help stabilize other antioxidants or prevent the color from changing in a product.
As an antioxidant, it helps fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material. Thus, antioxidants may reduce the signs of aging.
This ingredient is oil-soluble.
Learn more about Pentaerythrityl Tetra-Di-T-Butyl HydroxyhydrocinnamateThis ingredient is also known as castor oil. It is a skin conditioning ingredient.
The star component of castor oil is ricinoleic acid, an unusual fatty acid that makes up ~80-92% of its composition.
In skincare, it is an emollient that dries down to a solid film with water-binding properties. This helps keep skin hydrated and helps reduce transepidermal water loss (TEWL).
A 2026 dermatology review pulls together its broader uses:
Human clinical testing found this ingredient to be non-irritating and non-sensitizing.
Because castor oil contains fatty acids in the C11-24 range, this ingredient may not be fungal acne safe.
At this time, the literature does not support castor oil in regrowing hair. A 2022 systematic review found no strong evidence that it supports hair growth and only weak evidence that it improves hair shine.
Castor oil itself carries "perfuming" and "masking" function tags according to the official CosIng database. This is because of its mild odor and odor-dampening properties.
Learn more about Ricinus Communis Seed OilEthylhexyl Palmitate, also known as octyl palmitate, is created from 2-ethylhexyl alcohol and palmitic acid.
In cosmetics, it plays many roles:
One thing worth noting: a controlled study found this ingredient applied under occlusion to acne-prone subjects increased microcomedones. Just keep in mind this was under occlusive conditions and don't reflect how most products are used day-to-day.
For most people, this is a well-tolerated and lightweight ingredient.
This ingredient may not be fungal acne safe because it is an ester of palmitic acid, a C16 fatty acid that falls within the C11-24 range that Malassezia can metabolize.
Learn more about Ethylhexyl PalmitateButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolWe don't have a description for Mannose yet.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateHydrogenated Castor Oil (aka "castor wax") is what you get when castor oil is turned into a wax.
Its dominant fatty acid is ricinoleic acid, giving it both emollient and mild humectant properties.
According to EU CosIng, this ingredient helps soften skin, keep oil and water stay mixed, and thickens products.
Hydrogenated castor oil at 30% did not trigger a positive patch-test reaction and is well-tolerated.
Since this ingredient is based on an 18-carbon fatty acid, it falls into the chain-length range that Malassezia can feed on and may not be fungal acne safe.
Learn more about Hydrogenated Castor OilPentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolWe don't have a description for PEG-60 Sorbitan Tetrastearate yet.
We don't have a description for Rosa Rugosa Flower Extract yet.
We don't have a description for Myrothamnus Flabellifolia Leaf/Stem Extract yet.
Glucose is a simple sugar (a monosaccharide). In skincare, it is mostly a humectant and skin conditioning agent.
Mechanistically, it has multiple hydroxyl groups that hydrogen-bond to water. This pulls moisture into the upper layers of skin to keep the surface soft and hydrated.
It's worth knowing sugars are already a natural component of the skin's NMF (natural moisturizing factor) so it's a molecule that your stratum corneum is well-acquainted with.
Just so you know, glucose is hydrophilic (water-loving) and the stratum corneum is a strong barrier to hydrophilic compounds. This just means penetration is slow and most of the action is happening on the surface.
Gram-to-gram, glucose is not as efficient as a humectant as glycerin. This is why you'll likely see glycose paired with stronger humectants for a bigger hydration payoff.
In skincare, glucose is typically derived from corn or other starch sources.
Learn more about GlucoseIn cosmetics, vinegar is often used to help adjust the pH of a product. It is also a light exfoliant. The pH of your skin is important to maintain a healthy skin barrier.
Vinegar is created by the process of double-fermentation. It is an aqueous solution consisting mostly of water and acetic acid. Typically, vinegar contains anywhere from 5-8% acetic acid.
Other components include small amounts of contains small amounts of tartaric acid and citric acid. Depending on what is used to ferment the vinegar, it can have traces of flavoring as well.
Learn more about VinegarWe don't have a description for Rosa Hybrid Flower Extract yet.
You might know this ingredient as pomegranate fruit. It has been shown to have antioxidant, skin soothing and anti-aging benefits.
Pomegranates are rich in antioxidant compounds such as polyphenolic compounds such as ellagic acid, phenolic acids, anthocyanins, and flavonoids.
Both in-vivo and in-vitro studies show pomegranate fruit helps with:
These benefits offer skin anti-aging and skin soothing benefits.
Fun fact: The name pomegranate comes from two latin words: "pome" or apple, and "granate" or "many seeded".
Pomegranate flower extract is often confused for pomegranate fruit extract, but comes from the flowers of the tree.
Learn more about Punica Granatum Fruit ExtractSodium DNA is an emerging anti-aging ingredient.
It is created by taking deoxyribonucleic acid (DNA) and purifying it with sodium hydroxide.
The DNA is extracted from several different animal sources, including: calf thymus, the gonadic tissue of a male sturgeon, or herring / salmon sperm.
You have probably seen this ingredient in anti-aging skincare. But what is it?
DNA is composed of nucleotides, or chemical building blocks. Nucleotides include adenine (A), thymine (T), guanine (G), and cytosine (C). Talk about a flashback to biology! Nucleosides are formed from these nucleotides.
The science behind Sodium DNA is based on an ingredient called Polydeoxyribonucleotide or PDRN.
PDRN are DNA fragments mainly extracted from the sperm cells of trout or salmon. Meaning, PDRN can be derived from Sodium DNA.
PDRN consists of chains of nucleotides and nucleosides mentioned above. They can range anywhere from 80 - 2000 pairs.
Studies show PDRN has the following properties:
Most of the research on PDRN has been done using injectable forms. That’s important, because PDRN is a large molecule and doesn’t absorb well through the skin. So if you’re applying it topically, the effects are likely to be much milder.
Still, topical Sodium DNA is emerging as a trendy anti-aging ingredient. It’s generally well-tolerated and offers good biocompatibility with human skin, making it a low-risk addition to most routines.
Further studies are needed to truly confirm this ingredients anti-aging ability (Remember, retinol has decades of research!).
Sodium DNA may be sourced from fish, animal tissue, or plants. Since this isn’t always disclosed, we recommend asking the brand directly if the ingredient’s origin is important to you.
Learn more about Sodium DnaPalmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.
That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.
Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.
In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.
Human clinical data is promising, but modest:
A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.
A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.
You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.
Fungal acne note:
Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.
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Judydoll is a Chinese brand
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The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated December 8, 2025 • Added by anemone