Synergie Skin Hyalavive Versus DRMTLGY Needle-Less Serum
Updated on June 09, 2025
Overview
What they are
These products are both cruelty-free and reef safe serums. They have a total of 9 ingredients in common
Cool Features
They both contain ceramides and hyaluronic acid
Suited For
They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, scar healing and dark spots
Free From
They both do not contain any common allergens, oils, parabens or silicones
What's Inside
They both contain sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Synergie Skin Hyalavive 35 ingredients
DRMTLGY Needle-Less Serum 29 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
Synergie Skin Hyalavive 35 ingredients
DRMTLGY Needle-Less Serum 29 ingredients
Benefits
Concerns
Key Ingredients
Benefits
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
Humectant
Isoamyl Laurate
Emollient
Methylpropanediol
SolventPropanediol
Solvent
Betaine
Humectant
Panthenol
Skin Conditioning
Sodium PCA
Humectant
Hydrolyzed Tomato Skin
Skin ConditioningCaprylyl Glycol
EmollientSodium Lactate
BufferingSodium Hyaluronate
Humectant
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingCeramide NP
Skin Conditioning
Ceramide AP
Skin Conditioning
Cholesterol
Emollient
Phytosphingosine
Skin Conditioning
Sodium Cetearyl Sulfate
Cleansing
Ceramide EOP
Skin Conditioning
Behenic Acid
Cleansing
Cetearyl Alcohol
Emollient
Glyceryl Stearate
Emollient
Sodium Levulinate
Skin ConditioningCyanocobalamin
Skin ConditioningSphingomonas Ferment Extract
Skin ConditioningPolyglyceryl-10 Stearate
Skin Conditioning
Phenylpropanol
Masking
Sodium Phytate
Triethyl Citrate
Masking
Polyglyceryl-6 Behenate
Emulsion Stabilising
Citric Acid
Buffering
Potassium Sorbate
Preservative
Sodium Benzoate
Masking
Alcohol
Antimicrobial
Sodium Hydroxide
BufferingWater, Glycerin, Isoamyl Laurate, Methylpropanediol, Propanediol, Betaine, Panthenol, Sodium PCA, Hydrolyzed Tomato Skin, Caprylyl Glycol, Sodium Lactate, Sodium Hyaluronate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Ceramide NP, Ceramide AP, Cholesterol, Phytosphingosine, Sodium Cetearyl Sulfate, Ceramide EOP, Behenic Acid, Cetearyl Alcohol, Glyceryl Stearate, Sodium Levulinate, Cyanocobalamin, Sphingomonas Ferment Extract, Polyglyceryl-10 Stearate, Phenylpropanol, Sodium Phytate, Triethyl Citrate, Polyglyceryl-6 Behenate, Citric Acid, Potassium Sorbate, Sodium Benzoate, Alcohol, Sodium Hydroxide
Water
Skin ConditioningGlycerin
Humectant
Sodium Chondroitin Sulfate
Skin Conditioning
Sodium Hyaluronate
Humectant
Pisum Sativum Extract
Skin ConditioningBambusa Vulgaris Leaf/Stem Extract
HumectantPalmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Ceramide EOP
Skin Conditioning
Glucosamine Hcl
Glycosaminoglycans
EmollientCeramide NP
Skin Conditioning
Palmitoyl Tripeptide-5
Skin Conditioning
Ceramide AP
Skin Conditioning
Phytosphingosine
Skin Conditioning
Cholesterol
Emollient
Niacinamide
Smoothing
Sodium Lauroyl Lactylate
EmulsifyingMethylglucoside Phosphate
Skin ConditioningCopper Lysinate/Prolinate
Skin ConditioningPanthenol
Skin Conditioning
Tocopheryl Acetate
Antioxidant
Phenoxyethanol
Preservative
Polysorbate 20
Emulsifying
Ethylhexylglycerin
Skin ConditioningDisodium EDTA
Butylene Glycol
Humectant
Carbomer
Emulsion StabilisingXanthan Gum
EmulsifyingWater, Glycerin, Sodium Chondroitin Sulfate, Sodium Hyaluronate, Pisum Sativum Extract, Bambusa Vulgaris Leaf/Stem Extract, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP, Glucosamine Hcl, Glycosaminoglycans, Ceramide NP, Palmitoyl Tripeptide-5, Ceramide AP, Phytosphingosine, Cholesterol, Niacinamide, Sodium Lauroyl Lactylate, Methylglucoside Phosphate, Copper Lysinate/Prolinate, Panthenol, Tocopheryl Acetate, Phenoxyethanol, Polysorbate 20, Ethylhexylglycerin, Disodium EDTA, Butylene Glycol, Carbomer, Xanthan Gum
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Ceramide AP is a type of Ceramide.
Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. Having a strong skin barrier leads to more firm and hydrated skin.
They are known for their ability to hold water and thus are a great ingredient for dry skin. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.
If you would like to eat ceramides, sweet potatoes contain a small amount.
Read more about other common types of ceramides here:
Ceramide NP
Ceramide EOP
Ceramide EOP is a type of Ceramide.
EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base.
Ceramides are intercellular lipids naturally found in our skin. They bind dead skin cells together to create a barrier. The ceramides in our skin have the ability to hold water to keep our skin hydrated.
Ceramides are an important building block for our skin barrier. A strong skin barrier helps with:
If you would like to eat ceramides, sweet potatoes contain a small amount.
Read more about other common types of ceramides here:
Learn more about Ceramide EOPCeramide NP is a type of ceramide.
Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.
Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.
If you would like to eat ceramides, sweet potatoes contain a small amount.
Read more about other common types of ceramides here:
Ceramide AP
Ceramide EOP
Cholesterol is a class of organic molecules called lipids. It helps hydrate your skin and is essential to having a healthy skin barrier.
Our skin naturally contains cholesterol in the outermost layer. Besides cholesterol, it also contains ceramides and fatty acids. Cholesterol makes up about 1/4 of your skin's outer layer and barrier. Your skin barrier is responsible for keeping allergens and microbes out. Having a healthy skin barrier is also responsible for keeping your skin firm and plump.
Our bodies use cholestrol to create vitamin D, steroid hormones, and more.
Learn more about CholesterolGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPanthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolPhytosphingosine is a phospholipid naturally found in our skin as a building block for ceramides.. It helps moisturize, soothe, and protect skin.
Phytosphingosine contributes to your skin's natural moisturizing factor (NMF). The NMF is responsible for hydration, a strong barrier, and plasticity. Our NMF decreases with age. Increasing NMF leads to more healthy and hydrated skin.
Studies show products formulated with NMF ingredients help strengthen our skin's barrier. Having a healthy skin barrier reduces irritation and increases hydration. Our skin barrier is responsible for having plump and firm skin. It also helps protect our skin against infection, allergies, and inflammation.
Fun fact: Phytosphingosine is abundant in plants and fungi.
More ingredients that help boost collagen in skin:
Learn more about PhytosphingosineSodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterIngredient Ratings
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When to use
Synergie Skin Hyalavive 35 ingredients
DRMTLGY Needle-Less Serum 29 ingredients
Reviews
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