Versus

Sesderma Mandelac Moisturizing Cream Versus SkinCeuticals Metacell Renewal B3

General Moisturizer
Emulsion
Spanish Brand Spain
American Brand United States

Updated on April 04, 2025

Overview

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any sulfates

What's Inside

They both contain common allergens, fragrances, oils and silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Mandelac Moisturizing Cream

Water

Skin Conditioning

Isohexadecane

Emollient

C12-15 Alkyl Benzoate

Antimicrobial

Limnanthes Alba Seed Oil

Skin Conditioning
Oil IconNot safe for Fungal Acne Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Propylene Glycol

Humectant
0 / 0 Helps hydrate Dry Skin IconMay worsen Eczema IconMay worsen Rosacea Icon

Cetyl Alcohol

Emollient
2 / 2 Fatty Alcohol Icon

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

PEG-100 Stearate

0 / 0 Not safe for Fungal Acne Icon

Saccharide Isomerate

Humectant

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Aloe Barbadensis Leaf Juice

Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation Icon

Sodium PCA

Humectant
0 / 0

Urea

Buffering
Helps hydrate Dry Skin IconGood for Skin Texture IconMay worsen Eczema IconMay worsen Rosacea Icon

Mandelic Acid

Antimicrobial
AHA IconGood for Oily Skin IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Camellia Sinensis Leaf Extract

Antimicrobial
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging Icon

Glycolic Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Caprooyl Tetrapeptide-3

Skin Protecting
Peptide Icon

Retinol

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Sodium Lactate

Buffering

Hydrolyzed Collagen

Emollient
Helps hydrate Dry Skin IconHelps with Anti-Aging Icon

Malus Domestica Fruit Cell Culture Extract

Skin Conditioning

Allantoin

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Lecithin

Emollient

Alcohol

Antimicrobial
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon

Dimethicone

Emollient
1 / 0 Silicon Icon

Xanthan Gum

Emulsifying

Dipropylene Glycol

Masking

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Dextran

Sodium Hydroxide

Buffering

Disodium EDTA

Sodium Cholate

Skin Conditioning

Citric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Achillea Millefolium Extract

Cleansing

Chamomilla Recutita Extract

Skin Conditioning
0 / 0 Helps reduce irritation Icon

Viscum Album Leaf Extract

Soothing

Melissa Officinalis Leaf Oil

Masking
Fragrance IconOil Icon

Humulus Lupulus Extract

Antimicrobial

Foeniculum Vulgare Fruit Extract

Emollient

Ascorbyl Palmitate

Antioxidant
2 / 0 Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconNot safe for Fungal Acne Icon

Glyceryl Oleate

Emollient
Fragrance IconNot safe for Fungal Acne Icon

BHT

Antioxidant
Antioxidant Icon

BHA

Antioxidant
Antioxidant Icon

Phenoxyethanol

Preservative
Preservative Icon

Ethylparaben

Preservative
Preservative IconParaben IconNon-Reef-Safe Icon

Methylparaben

Preservative
0 / 0 Preservative IconParaben IconNon-Reef-Safe IconMay worsen Eczema Icon

Potassium Sorbate

Preservative
Preservative Icon

Propylparaben

Preservative
0 / 0 Preservative IconParaben IconCan worsen Dry Skin IconNon-Reef-Safe Icon

Parfum

Masking
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon

Coumarin

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Citral

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Rosacea Icon

Eugenol

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Limonene

Perfuming
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon

Isoeugenol

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon
Metacell Renewal B3

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Emollient, Skin Conditioning, Skin Protecting

Dimethicone is a type of synthetic silicone created from natural materials such as quartz.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Learn more about Dimethicone

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Perfuming

Citral is a fragrance and used to add a lemon-like scent to products. It is both naturally found in plants and created synthetically. In plants, it is commonly occurring in lemon myrtle, lemongrass, lemon tea-tree, lemon verbena, and other citruses.

The EU mandates Citral be listed separately as a fragrance. It is a known allergen and may cause contact dermatitis. Citral can also used as a masking ingredient.

The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.

The term 'citral' is a collective term for two geometric isomers: geranial/Citral A and neral/Citral B.

Learn more about Citral
Perfuming, Solvent

Limonene is a fragrance that adds scent and taste to a formulation.

It's found in the peel oil of citrus fruits and other plants such as lavender and eucalyptus. The scent of limonene is generally described as "sweet citrus".

Limonene acts as an antioxidant, meaning it helps neutralize free radicals.

When exposed to air, oxidized limonene may sensitize the skin. Because of this, limonene is often avoided by people with sensitive skin.

The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.

Learn more about Limonene

When to use

6 Routines
50% use in am
50% use in pm
100% use every day
36 Routines
56% use in am
44% use in pm
97% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Sesderma Mandelac Moisturizing Cream 57 ingredients

1.0 /5
from 1 rating
kevin10's avatar

Kevin

2 months ago
Review

wrong ingredients description

SkinCeuticals Metacell Renewal B3 29 ingredients

5.0 /5
from 1 rating