Remedy For Daily Defense 15% Vitamin C Antioxidant Complex Brightening Serum Versus Cetaphil Healthy Radiance Antioxidant-C Serum
This brightening serum is formulated around 3-O-Ethyl Ascorbic Acid and Ferulic Acid to brighten dull-looking skin and calm redness.
This brightening serum is formulated around Sodium Ascorbyl Phosphate and Niacinamide to brighten dull-looking skin and fade the look of dark spots.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin Conditioning3-O-Ethyl Ascorbic Acid
Skin ConditioningGlycerin
HumectantPropanediol
SolventSqualane
EmollientC12-15 Alkyl Lactate
EmollientButylene Glycol
HumectantAloe Barbadensis Leaf Juice
Skin ConditioningPolyglyceryl-10 Laurate
Skin ConditioningHydrolyzed Hyaluronic Acid
HumectantAllantoin
Skin ConditioningPanthenol
Skin ConditioningEscin
TonicRuscus Aculeatus Root Extract
AstringentAmmonium Glycyrrhizate
MaskingCentella Asiatica Leaf Extract
Skin ConditioningHydrolyzed Yeast Protein
Skin ConditioningCalendula Officinalis Flower Extract
MaskingTocopheryl Acetate
AntioxidantAcetyl Zingerone
AntioxidantSuperoxide Dismutase
AntioxidantErgothioneine
AntioxidantPlankton Extract
Skin ConditioningSpirulina Platensis Extract
Skin ProtectingBifida Ferment Lysate
Skin ConditioningFerulic Acid
AntimicrobialEctoin
Skin Conditioning1,2-Hexanediol
Skin ConditioningCurcuma Longa Root Extract
AntioxidantGlycyrrhiza Glabra Root Extract
BleachingCamellia Sinensis Leaf Extract
AntimicrobialHydroxyacetophenone
AntioxidantTrisodium Ethylenediamine Disuccinate
Sodium Citrate
BufferingCitric Acid
BufferingSodium Hydroxide
BufferingSodium Benzoate
MaskingPotassium Sorbate
PreservativeLeuconostoc/Radish Root Ferment Filtrate
AntimicrobialPhenoxyethanol
PreservativeEthylhexylglycerin
Skin ConditioningWater, 3-O-Ethyl Ascorbic Acid, Glycerin, Propanediol, Squalane, C12-15 Alkyl Lactate, Butylene Glycol, Aloe Barbadensis Leaf Juice, Polyglyceryl-10 Laurate, Hydrolyzed Hyaluronic Acid, Allantoin, Panthenol, Escin, Ruscus Aculeatus Root Extract, Ammonium Glycyrrhizate, Centella Asiatica Leaf Extract, Hydrolyzed Yeast Protein, Calendula Officinalis Flower Extract, Tocopheryl Acetate, Acetyl Zingerone, Superoxide Dismutase, Ergothioneine, Plankton Extract, Spirulina Platensis Extract, Bifida Ferment Lysate, Ferulic Acid, Ectoin, 1,2-Hexanediol, Curcuma Longa Root Extract, Glycyrrhiza Glabra Root Extract, Camellia Sinensis Leaf Extract, Hydroxyacetophenone, Trisodium Ethylenediamine Disuccinate, Sodium Citrate, Citric Acid, Sodium Hydroxide, Sodium Benzoate, Potassium Sorbate, Leuconostoc/Radish Root Ferment Filtrate, Phenoxyethanol, Ethylhexylglycerin
Water
Skin ConditioningSodium Ascorbyl Phosphate
AntioxidantMethyl Gluceth-20
HumectantButylene Glycol
HumectantBis-PEG-18 Methyl Ether Dimethyl Silane
EmollientNiacinamide
SmoothingGlycerin
HumectantCitric Acid
BufferingXanthan Gum
EmulsifyingPhenoxyethanol
PreservativeSorbitan Oleate Decylglucoside Crosspolymer
CleansingHydroxyacetophenone
AntioxidantAlcohol
AntimicrobialDisodium EDTA
Sodium PCA
HumectantCaprylyl Glycol
EmollientMalva Sylvestris Flower/Leaf/Stem Extract
Skin ConditioningMentha Piperita Leaf Extract
Skin ConditioningPrimula Veris Flower Extract
Skin ConditioningAlchemilla Vulgaris Flower/Leaf/Stem Extract
AstringentVeronica Officinalis Flower/Leaf/Stem Extract
AstringentMelissa Officinalis Leaf Extract
Skin ConditioningAchillea Millefolium Flower/Leaf/Stem Extract
Skin ConditioningErythritol
HumectantCarrageenan
Citrus Paradisi Peel Extract
PerfumingCitrus Aurantium Dulcis Peel Extract
Emulsion StabilisingBenzoic Acid
MaskingSodium Hydroxide
BufferingSorbic Acid
PreservativeCitrus Limon Peel Extract
EmollientBHT
AntioxidantWater, Sodium Ascorbyl Phosphate, Methyl Gluceth-20, Butylene Glycol, Bis-PEG-18 Methyl Ether Dimethyl Silane, Niacinamide, Glycerin, Citric Acid, Xanthan Gum, Phenoxyethanol, Sorbitan Oleate Decylglucoside Crosspolymer, Hydroxyacetophenone, Alcohol, Disodium EDTA, Sodium PCA, Caprylyl Glycol, Malva Sylvestris Flower/Leaf/Stem Extract, Mentha Piperita Leaf Extract, Primula Veris Flower Extract, Alchemilla Vulgaris Flower/Leaf/Stem Extract, Veronica Officinalis Flower/Leaf/Stem Extract, Melissa Officinalis Leaf Extract, Achillea Millefolium Flower/Leaf/Stem Extract, Erythritol, Carrageenan, Citrus Paradisi Peel Extract, Citrus Aurantium Dulcis Peel Extract, Benzoic Acid, Sodium Hydroxide, Sorbic Acid, Citrus Limon Peel Extract, BHT
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCitric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Read more about some other popular AHA's here:
Learn more about Citric AcidGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinHydroxyacetophenone is a small phenolic molecule that earns its place in a formulas as an antioxidant and preservative booster.
As a phenol, it is able to neutralize free radicals to protect both the product and the skin from oxidative stress.
Though it can't kill microbes on its own, it works as a good supporting agent when combined with other preservatives like Phenoxyethanol or 1,2-Hexanediol.
This ingredient naturally occurs as piceol in Norwegian spruce needles (~0.4-1.1% dry weight and in cloudberries). Though the cosmetic-grade material is synthesized for purity and consistency.
You'll usually see it used at low levels and suppliers recommend up to 1% added to a water phase.
Safety testing was done at concentrations like 0.05% in SPF products and 0.5% in a Human Repeated Insult Patch Test. The safety evidence is assuring; this ingredient is safe for cosmetics in current use and also holds safety status as a food flavoring as well.
An honest caveat: the "soothing" and "anti-inflammatory" claims come mostly from supplier marketing rather than published clinical trials. The Cosmetic Ingredient Review's own literature search found no useful efficacy studies on this ingredient.
So the antioxidant and preservative-boosting roles are the well supported ones while the calming benefit is plausible but thinly evidenced.
Overall, this is a well-tolerated, low-irritation multitasker that quietly helps a formula stay fresh and stable.
Learn more about HydroxyacetophenonePhenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water