Versus

Medik8 Advanced Pro-Collagen+ Peptide Cream Versus Paula's Choice Pro-Collagen Peptide Plumping Moisturizer

General Moisturizer
General Moisturizer
British Brand United Kingdom
American Brand United States

Updated on September 15, 2025

Overview

What they are

These products are both cruelty-free and reef safe general moisturizers. They have a total of 9 ingredients in common

Cool Features

They both contain ceramides and peptides

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin and scar healing

Free From

They both do not contain any harsh alcohols, common allergens, oils, parabens or sulfates

What's Inside

They both contain silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside

What's inside

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Advanced Pro-Collagen+ Peptide Cream

Water

Skin Conditioning

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Lavandula Angustifolia Flower Water

Skin Conditioning
May cause irritation Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Dimethicone

Emollient
1 / 0 Silicon Icon

Stearic Acid

Cleansing
2-3 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Phytosteryl Oleate

Skin Conditioning

C12-16 Alcohols

Emollient

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Emulsion Stabilising

Maltodextrin

Absorbent
Helps hydrate Dry Skin Icon

Carnosine

Skin Conditioning
Helps with Anti-Aging IconGood for Scar Healing Icon

Rosmarinus Officinalis Water

Masking

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Butyrospermum Parkii Butter

Skin Conditioning
Helps hydrate Dry Skin IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Linoleic Acid

Cleansing
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Cetearyl Olivate

Not safe for Fungal Acne Icon

Palmitic Acid

Emollient
2 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Behenyl Alcohol

Emollient
Fatty Alcohol Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Collagen Amino Acids

Moisturising
Helps hydrate Dry Skin IconHelps with Anti-Aging Icon

Micrococcus Lysate

Skin Conditioning

Hydrogenated Lecithin

Emulsifying
Helps hydrate Dry Skin Icon

Oligopeptide-1

Skin Conditioning
Peptide Icon

Sorbitan Olivate

Emulsifying
Not safe for Fungal Acne Icon

Helianthus Annuus Sprout Extract

Skin Conditioning

Xanthan Gum

Emulsifying

Citric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Ethylhexylglycerin

Skin Conditioning

Sodium Gluconate

Skin Conditioning

Sodium Polyglutamate

Humectant

Acetyl Glucosamine

Skin Conditioning

Hydroxyacetophenone

Antioxidant
Antioxidant IconHelps reduce irritation Icon

Phytosterols

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Sodium Lauroyl Lactylate

Emulsifying

Lecithin

Emollient
Helps hydrate Dry Skin Icon

Cholesterol

Emollient
0 / 0 Helps hydrate Dry Skin Icon

Ceteareth-25

Cleansing

Ceramide AP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Phytosphingosine

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation Icon

Carbomer

Emulsion Stabilising
1 / 0

Cetyl Alcohol

Emollient
2 / 2 Fatty Alcohol Icon

Behenic Acid

Cleansing
0 / 0 Helps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Ceramide Ns

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide EOP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide Eos

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Caprooyl Phytosphingosine

Skin Conditioning
Helps hydrate Dry Skin Icon

Caprooyl Sphingosine

Skin Conditioning

Phenoxyethanol

Preservative
Preservative Icon

Ascorbyl Palmitate

Antioxidant
2 / 0 Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconNot safe for Fungal Acne Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

Glyceryl Oleate

Emollient
Fragrance IconNot safe for Fungal Acne Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning

Ceramide AP is a type of Ceramide.

Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. Having a strong skin barrier leads to more firm and hydrated skin.

They are known for their ability to hold water and thus are a great ingredient for dry skin. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.

If you would like to eat ceramides, sweet potatoes contain a small amount.

Read more about other common types of ceramides here:
Ceramide NP
Ceramide EOP

Learn more about Ceramide AP
Emollient, Skin Conditioning, Skin Protecting

Dimethicone is a type of synthetic silicone created from natural materials such as quartz.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Learn more about Dimethicone
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Antioxidant

Hydroxyacetophenone is antioxidant with skin conditioning and soothing properties. It also boosts the efficiency of preservatives.

This ingredient is not irritating or sensitizing.

Emollient, Emulsifying, Skin Conditioning

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.

This ingredient has emollient and emulsifying properties.

As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.

As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.

This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.

Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.

We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.

Some other names for this ingredient include soy lecithin and deoiled soy lecithin.

Learn more about Lecithin
Skin Conditioning

This synthetic peptide consists of glycine, histidine, and lysine. Peptides have skin conditioning properties.

This name refers to a group of Oligopeptide-1 derivatives, such as the famous Sh-Oligopeptide-1.

Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Emollient, Skin Conditioning

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.

Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.

Research shows that squalane is non-irritating (even at 100% concentration).

In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.

The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.

Is squalane vegan?

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Is squalane an oil?

Squalane is often called an oil, but it’s technically not; it’s a hydrocarbon, meaning it’s only made of carbon and hydrogen, unlike true oils which are triglycerides made of fatty acids and glycerol.

The term “oil-free” isn’t regulated, so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

While some people avoid oils thinking they cause breakouts, the right kind of oil (or oil-like ingredient like squalane) can actually help balance and hydrate your skin. It’s worth testing out simple oils or squalane to see what works best for your skin.

Learn more about Squalane
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

4 Routines
75% use in am
25% use in pm
100% use every day
316 Routines
42% use in am
58% use in pm
95% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

No reviews yet

Be the first to review Advanced Pro-Collagen+ Peptide Cream

Write the first review
3.71
Overall rating
5
4
3
2
1
What people say
Works Well 67% No Scent 50% Absorbs Well 33%