Tridecapeptide-1
Explained
Tridecapeptide-1 is a synthetic peptide that gets marketed as a "Botox-like" because it is a neutrotransmitter peptide.
Your skin uses a chemical called acetylcholine to tell tiny facial muscles to move and Tridecapeptide-1 tries to take that chemical's spot. This makes muscles stay a little more relaxed and helps lines like crow's feet look softer.
Concentration-wise, the numbers come mostly from suppliers and brands; typical leave-on use lands between 1-10%.
The supplier does report that 1-3% gives a subtle short-term smoothing effect within 15 minutes to an hour for some users. Higher levels (3-10%) showed stronger results after four week of twice-daily use.
You might also see this ingredient paired with glycols at 2-5% to help performance.
At this time, all the efficacy data traces back to the supplier's in-house testing and not third-party trials. Though the bigger category this ingredient belongs to ("neuro" peptides) do have some published research suggesting topical peptides can give mild cosmetic smoothing.
See all 18 products with Tridecapeptide-1
