La Roche-Posay Lipikar Daily Repair Moisturizing Lotion Versus Cetaphil Redness Relieving Night Moisturizer
This calming night moisturizer is formulated around Allantoin and Dipotassium Glycyrrhizate to calm redness and strengthen the skin barrier.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningButyrospermum Parkii Butter
Skin ConditioningGlycerin
HumectantSorbitan Stearate
EmulsifyingParaffinum Liquidum
EmollientNiacinamide
SmoothingVitis Vinifera Seed Oil
EmollientAluminum Starch Octenylsuccinate
AbsorbentDimethicone
EmollientBeeswax
Emulsion StabilisingSorbitan Tristearate
EmulsifyingCarbomer
Emulsion StabilisingSodium Hydroxide
BufferingPoloxamer 338
EmulsifyingAmmonium Polyacryloyldimethyl Taurate
Emulsion StabilisingDisodium EDTA
ChelatingSucrose Cocoate
EmulsifyingCaprylyl Glycol
EmollientCitric Acid
BufferingT-Butyl Alcohol
PerfumingCetyl Palmitate
EmollientBHT
AntioxidantPentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
AntioxidantChlorhexidine Digluconate
AntimicrobialWater, Butyrospermum Parkii Butter, Glycerin, Sorbitan Stearate, Paraffinum Liquidum, Niacinamide, Vitis Vinifera Seed Oil, Aluminum Starch Octenylsuccinate, Dimethicone, Beeswax, Sorbitan Tristearate, Carbomer, Sodium Hydroxide, Poloxamer 338, Ammonium Polyacryloyldimethyl Taurate, Disodium EDTA, Sucrose Cocoate, Caprylyl Glycol, Citric Acid, T-Butyl Alcohol, Cetyl Palmitate, BHT, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Chlorhexidine Digluconate
Water
Skin ConditioningCaprylic/Capric Triglyceride
MaskingGlycerin
HumectantPropanediol
SolventPentylene Glycol
Skin ConditioningHelianthus Annuus Seed Oil
EmollientSorbitol
HumectantDimethicone
EmollientButyrospermum Parkii Butter
Skin ConditioningCetearyl Alcohol
EmollientBehenyl Alcohol
EmollientGlyceryl Stearate
EmollientSodium Hydroxide
BufferingTocopheryl Acetate
AntioxidantAllantoin
Skin ConditioningDipotassium Glycyrrhizate
HumectantSodium Hyaluronate
HumectantCeramide NP
Skin ConditioningPanthenol
Skin ConditioningCaffeine
Skin ConditioningCitric Acid
BufferingCetyl Alcohol
EmollientCeteareth-20
CleansingGlyceryl Stearate Citrate
EmollientDisodium Ethylene Dicocamide PEG-15 Disulfate
CleansingNiacinamide
SmoothingCaprylyl Glycol
EmollientAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingDisodium EDTA
ChelatingXanthan Gum
EmulsifyingBHT
AntioxidantWater, Caprylic/Capric Triglyceride, Glycerin, Propanediol, Pentylene Glycol, Helianthus Annuus Seed Oil, Sorbitol, Dimethicone, Butyrospermum Parkii Butter, Cetearyl Alcohol, Behenyl Alcohol, Glyceryl Stearate, Sodium Hydroxide, Tocopheryl Acetate, Allantoin, Dipotassium Glycyrrhizate, Sodium Hyaluronate, Ceramide NP, Panthenol, Caffeine, Citric Acid, Cetyl Alcohol, Ceteareth-20, Glyceryl Stearate Citrate, Disodium Ethylene Dicocamide PEG-15 Disulfate, Niacinamide, Caprylyl Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Disodium EDTA, Xanthan Gum, BHT
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
BHT is a synthetic antioxidant and preservative.
As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.
As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.
The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.
However, it was recently restricted for use in the UK as of April 2024.
Learn more about BHTThis ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients.
Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL).
In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).
Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.
Shea butter also contains vitamins A and E which may contribute to antioxidant activity.
While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.
This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.
This ingredient shows up on a lot of "pore-clogging" lists but there's no real evidence behind that. It doesn't even have a comedogenic rating from an actual study; the numbers you'll find online come from blogs citing other blogs.
Ratings for other ingredients mostly come from a 1980s rabbit ear test. This test doesn't translate well to human skin or to real products because the ingredient sits at a much lower percentage.
Some people still find it breaks them out. So if that's you, definitely trust your skin. Just know this one's based on experience and not evidence.
Learn more about Butyrospermum Parkii ButterCaprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolCitric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.
However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.
Learn more about Citric AcidDimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water