This anti-aging ampoule is formulated around Niacinamide and Adenosine to soften the look of wrinkles and strengthen the skin barrier.
This hydrating ampoule is formulated around Niacinamide and Avena Sativa Kernel Extract to hydrate skin and strengthen the skin barrier.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningButylene Glycol
HumectantGlycerin
HumectantDipropylene Glycol
HumectantNiacinamide
Smoothing1,2-Hexanediol
Skin ConditioningSqualane
EmollientGlyceryl Polymethacrylate
Cetearyl Alcohol
EmollientAmmonium Acryloyldimethyltaurate/Vp Copolymer
Glyceryl Stearate
EmollientXanthan Gum
EmulsifyingAllantoin
Skin ConditioningHydrogenated Lecithin
EmulsifyingEthylhexylglycerin
Skin ConditioningStearic Acid
CleansingPolyglyceryl-3 Methylglucose Distearate
EmulsifyingAdenosine
Skin ConditioningPalmitic Acid
EmollientParfum
MaskingDisodium EDTA
ChelatingSodium Hyaluronate
HumectantLimonene
PerfumingCamellia Sinensis Leaf Extract
AntimicrobialDextrin
AbsorbentTheobroma Cacao Extract
Skin ConditioningLinalool
PerfumingCitronellol
PerfumingMyristic Acid
CleansingPentylene Glycol
Skin ConditioningLauric Acid
CleansingTocopherol
AntioxidantAcrylates/Stearyl Methacrylate Copolymer
Emulsion StabilisingTremella Fuciformis Sporocarp Extract
AntioxidantHyaluronic Acid
HumectantAchillea Millefolium Extract
CleansingCeramide NP
Skin ConditioningWater, Butylene Glycol, Glycerin, Dipropylene Glycol, Niacinamide, 1,2-Hexanediol, Squalane, Glyceryl Polymethacrylate, Cetearyl Alcohol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Glyceryl Stearate, Xanthan Gum, Allantoin, Hydrogenated Lecithin, Ethylhexylglycerin, Stearic Acid, Polyglyceryl-3 Methylglucose Distearate, Adenosine, Palmitic Acid, Parfum, Disodium EDTA, Sodium Hyaluronate, Limonene, Camellia Sinensis Leaf Extract, Dextrin, Theobroma Cacao Extract, Linalool, Citronellol, Myristic Acid, Pentylene Glycol, Lauric Acid, Tocopherol, Acrylates/Stearyl Methacrylate Copolymer, Tremella Fuciformis Sporocarp Extract, Hyaluronic Acid, Achillea Millefolium Extract, Ceramide NP
Water
Skin ConditioningMethylpropanediol
SolventGlycerin
HumectantCyclohexasiloxane
Emollient1,2-Hexanediol
Skin ConditioningNiacinamide
SmoothingPolyglycerin-3
HumectantAvena Sativa Kernel Extract
AbrasiveCynara Scolymus Leaf Extract
Skin ConditioningGlycine Soja Seed Extract
Skin ConditioningCamellia Sinensis Leaf Water
MaskingSodium Hyaluronate
HumectantHydrogenated Lecithin
EmulsifyingCitrus Aurantium Dulcis Peel Oil
MaskingCitrus Aurantium Bergamia Fruit Oil
MaskingLavandula Angustifolia Oil
MaskingAnthemis Nobilis Flower Oil
MaskingOctyldodeceth-16
EmulsifyingAmmonium Acryloyldimethyltaurate/Vp Copolymer
Xanthan Gum
EmulsifyingAdenosine
Skin ConditioningMethyl Diisopropyl Propionamide
MaskingCarbomer
Emulsion StabilisingDisodium EDTA
ChelatingTromethamine
BufferingPolyquaternium-51
Skin ConditioningBeta-Glucan
Skin ConditioningHydroxypropyltrimonium Hyaluronate
Hydrolyzed Sodium Hyaluronate
Skin ConditioningSodium Acetylated Hyaluronate
HumectantPropanediol
SolventHydrolyzed Hyaluronic Acid
HumectantTetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate
Skin ConditioningHyaluronic Acid
HumectantMagnesium Chloride
Sodium Hyaluronate Crosspolymer
HumectantArginine
MaskingTetrahydropiperine
Skin ConditioningPotassium Hyaluronate
Skin ConditioningPhloretin
AntioxidantEthylhexylglycerin
Skin ConditioningPentylene Glycol
Skin ConditioningLimonene
PerfumingLinalool
PerfumingWater, Methylpropanediol, Glycerin, Cyclohexasiloxane, 1,2-Hexanediol, Niacinamide, Polyglycerin-3, Avena Sativa Kernel Extract, Cynara Scolymus Leaf Extract, Glycine Soja Seed Extract, Camellia Sinensis Leaf Water, Sodium Hyaluronate, Hydrogenated Lecithin, Citrus Aurantium Dulcis Peel Oil, Citrus Aurantium Bergamia Fruit Oil, Lavandula Angustifolia Oil, Anthemis Nobilis Flower Oil, Octyldodeceth-16, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Xanthan Gum, Adenosine, Methyl Diisopropyl Propionamide, Carbomer, Disodium EDTA, Tromethamine, Polyquaternium-51, Beta-Glucan, Hydroxypropyltrimonium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Propanediol, Hydrolyzed Hyaluronic Acid, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Hyaluronic Acid, Magnesium Chloride, Sodium Hyaluronate Crosspolymer, Arginine, Tetrahydropiperine, Potassium Hyaluronate, Phloretin, Ethylhexylglycerin, Pentylene Glycol, Limonene, Linalool
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Learn more about AdenosineAmmonium Acryloyldimethyltaurate/Vp Copolymer is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.
Think of it as a supportive ingredient that helps your gel-creams feel silky, "cloud cream-like", and spread evenly without being greasy.
The Cosmetic Ingredient Review (CIR) Expert Panel evaluated it (along with 22 other acryloyldimethyltaurate polymers) and concluded it's:
Due to its large molecular size, it sits on the surface of skin rather than penetrating it.
Learn more about Ammonium Acryloyldimethyltaurate/Vp CopolymerDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinHyaluronic acid (HA) is a glycosaminoglycan (basically a long sugar chain) that your skin already makes on its own. In your skin, HA lives in the extracellular matrix and acts as the body's moisture reservoir.
Topically, HA is a humectant that binds water and helps skin look more plump, smooth, and hydrated.
The only catch is that HA isn't a single thing; it actually comes in a wide range of molecular weights (~50 - 2,000+ kDA) and size matters.
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
This is why the best HA serums blend the two sizes together so you get the best of both worlds.
The majority of cosmetic HA is produced by bacterial fermentation, typically using Streptococcus or Bacillus strains. Typical use levels in skincare sit around 0.1-2%.
A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance.
These are some other common types of Hyaluronic Acid:
Learn more about Hyaluronic AcidHydrogenated Lecithin is a more stable version of lecithin.
It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.
This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.
Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.
A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).
Learn more about Hydrogenated LecithinLimonene is the compound that gives citrus peel its smell.
In skincare, it shows up as a standalone fragrance ingredient or as a natural compound of citrus and other essential oils.
You'll typically see this ingredient used in very small amounts; anything above 0.001% in a leave-on product or 0.01% in a rinse-off has to be named on the label in the EU. The citrus oils that carry it sit around 0.5-1% in a finished formula.
Fresh limonene is a weak allergen; the real issue is that it slowly reacts with air and then breaks down from oxidation to create hydroperoxides (which are strong sensitizers). This is why suppliers are required to keep the peroxide value below 20 mmol.
Positive reactions in people being investigated for eczema vary:
It's worth skipping if you have a known fragrance allergy or a compromised barrier, but the risk is low for most people.
Older or long-opened products are also more likely to bother you than fresh ones due to oxidation.
Learn more about LimoneneLinalool is a small, naturally occurring scent molecule found in plants like lavender, coriander, bergamot, and more.
It is one of the two most-used fragrance ingredients in cosmetics and added purely for smell. Since it's not used for a skin benefit, there's no "effective dose". Concentration depends on the fragrance load of the product.
The EU requires it to be named on the label above 0.001% in leave-on and 0.01% in rinse-off products.
Fresh linalool is a weak sensitizer but air exposure turns some of it into hydroperoxides, which are strong sensitizers. Those oxidation products are the actual allergy concern.
Patch-test clinics see positive reactions to linalool hydroperoxides in about 4% to 12% of dermatitis patients depending on country and test concentration.
Resassuringly, one analytical study found hydroperoxide levels in real fragranced products to be orders of magnitude below what induced sensitization in animal studies with no evidence of oxidation building up during normal storage.
The practical takeaway is that linalool is fine for most people but worth avoiding if you have a confirmed fragrance contact allergy or a badly compromised barrier.
Products stored a long time after opening are also the high-risk scenario since that is when oxidation happens.
The scent of linalool is described as floral, spicy tropical, and citrus-like.
Learn more about LinaloolNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamidePentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Learn more about Pentylene GlycolSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan Gum