Glymed Plus Comfort Cream With Aloe Vera Versus Paula's Choice Moisture Boost Hydrating Treatment Cream
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Allantoin
Skin Conditioning
Aloe Barbadensis Leaf Juice
Skin Conditioning
Anthemis Nobilis Flower Extract
Masking
Arbutin
Antioxidant
Calendula Officinalis Flower Extract
Masking
Carbomer
Emulsion StabilisingCetyl Alcohol
Emollient
Epigallocatechin Gallatyl Glucoside
Antioxidant
Ethylhexylglycerin
Skin ConditioningGallyl Glucoside
Antioxidant
Glycerin
Humectant
Glyceryl Stearate
Emollient
Glycyrrhiza Glabra Root Extract
Bleaching
Hyaluronic Acid
Humectant
PEG-100 Stearate
Petrolatum
Emollient
Phenoxyethanol
Preservative
Propyl Gallate
Antioxidant
Sodium Hydroxide
BufferingSqualane
Emollient
Tetrahydrodiferuloylmethane
Antioxidant
Water
Skin ConditioningAllantoin, Aloe Barbadensis Leaf Juice, Anthemis Nobilis Flower Extract, Arbutin, Calendula Officinalis Flower Extract, Carbomer, Cetyl Alcohol, Epigallocatechin Gallatyl Glucoside, Ethylhexylglycerin, Gallyl Glucoside, Glycerin, Glyceryl Stearate, Glycyrrhiza Glabra Root Extract, Hyaluronic Acid, PEG-100 Stearate, Petrolatum, Phenoxyethanol, Propyl Gallate, Sodium Hydroxide, Squalane, Tetrahydrodiferuloylmethane, Water
Water
Skin ConditioningEthylhexyl Stearate
Emollient
Simmondsia Chinensis Seed Oil
Emollient
Butylene Glycol
Humectant
Glycerin
Humectant
Petrolatum
Emollient
Cetearyl Alcohol
Emollient
Dipentaerythrityl Hexacaprylate/Hexacaprate
EmulsifyingTridecyl Trimellitate
EmollientSodium Hyaluronate
Humectant
Ceramide NP
Skin Conditioning
Cholesterol
Emollient
Tocopherol
Antioxidant
Squalane
Emollient
Magnesium Ascorbyl Phosphate
Antioxidant
Dimethicone
Emollient
Niacinamide
Smoothing
Polysorbate 60
Emulsifying
Hydrolyzed Jojoba Protein
Skin ConditioningHydrolyzed Wheat Protein
Skin ConditioningAvena Sativa Kernel Extract
Abrasive
Hydrogenated Lecithin
Emulsifying
Whey Protein
Skin ConditioningTridecyl Stearate
Emollient
Neopentyl Glycol Dicaprylate/Dicaprate
EmollientPhenyl Trimethicone
Skin Conditioning
Myristyl Myristate
Emollient
Linoleic Acid
Cleansing
Linolenic Acid
Cleansing
Decarboxy Carnosine Hcl
Skin ConditioningHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingCetearyl Glucoside
Emulsifying
Cetyl Alcohol
Emollient
Polyglyceryl-3 Beeswax
Emulsifying
Aminomethyl Propanol
BufferingDisodium EDTA
Benzoic Acid
Masking
Chlorphenesin
Antimicrobial
Sorbic Acid
Preservative
Phenoxyethanol
Preservative
Water, Ethylhexyl Stearate, Simmondsia Chinensis Seed Oil, Butylene Glycol, Glycerin, Petrolatum, Cetearyl Alcohol, Dipentaerythrityl Hexacaprylate/Hexacaprate, Tridecyl Trimellitate, Sodium Hyaluronate, Ceramide NP, Cholesterol, Tocopherol, Squalane, Magnesium Ascorbyl Phosphate, Dimethicone, Niacinamide, Polysorbate 60, Hydrolyzed Jojoba Protein, Hydrolyzed Wheat Protein, Avena Sativa Kernel Extract, Hydrogenated Lecithin, Whey Protein, Tridecyl Stearate, Neopentyl Glycol Dicaprylate/Dicaprate, Phenyl Trimethicone, Myristyl Myristate, Linoleic Acid, Linolenic Acid, Decarboxy Carnosine Hcl, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Cetearyl Glucoside, Cetyl Alcohol, Polyglyceryl-3 Beeswax, Aminomethyl Propanol, Disodium EDTA, Benzoic Acid, Chlorphenesin, Sorbic Acid, Phenoxyethanol
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.
Its main roles are:
Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.
The FDA allows products labeled "alcohol-free" to have fatty alcohols.
Learn more about Cetyl AlcoholGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPetrolatum is more commonly known as petroleum jelly. It is created by mixing waxes and mineral oils.
This ingredient is effective at reducing water loss by 99%. This is because it is an occlusive. Occlusives create a hydrophobic barrier on the skin to prevent evaporation. This property makes it great for hydrating dry skin.
Pro tip: Use occlusives, such as this ingredient, on damp skin for the best results.
The quality or origin of petrolatum is only known when disclosed by the brand. Most cosmetic petrolatum has gone through several purification stages.
Another benefit of occlusives is it protects your skin against infection or allergies.
Petrolatum is fungal acne safe. It is a hydrocarbon with no fatty acid structure, so Malassezia cannot metabolize it. In-vitro studies support negligible growth stimulation as well.
It's also worth noting that petrolatum has a comedogenic rating of 0. In updated rabbit ear testing (and in human testing), petrolatum was found to be not comedogenic. This means it didnāt promote comedone formation in standard models.
Learn more about PetrolatumPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, itās technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term āoil-freeā isnāt regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Learn more about SqualaneWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water
