Versus

Dr. Althea 147 Barrier Cream Versus MediCube AGE-R Collagen Booster Gel Serum

General Moisturizer
Serum
Korean Brand
Korean Brand

Updated on June 12, 2025

Overview

What they are

These products are both cruelty-free and reef safe . They have a total of 16 ingredients in common

Cool Features

They both contain ceramides and hyaluronic acid

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, parabens or sulfates

What's Inside

They both contain fragrances and oils

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
147 Barrier Cream

Water

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Dipropylene Glycol

Masking

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Methyl Trimethicone

Skin Conditioning
Silicon Icon

Hydrogenated Polydecene

Emollient

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

Phenyl Trimethicone

Skin Conditioning
Silicon Icon

Vegetable Oil

Skin Conditioning
Oil IconNot safe for Fungal Acne Icon

Dimethicone/Vinyl Dimethicone Crosspolymer

Skin Conditioning
Silicon Icon

Glyceryl Stearate Se

Emulsifying
3 / 2 Bad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Artemisia Princeps Leaf Extract

Skin Conditioning

Persea Gratissima Fruit Extract

Emollient

Brassica Oleracea Acephala Leaf Extract

Humectant

Laminaria Japonica Extract

Skin Protecting
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Eclipta Prostrata Leaf Extract

Skin Conditioning

Beta Vulgaris Root Extract

Skin Conditioning

Chamaecyparis Obtusa Leaf Extract

Skin Conditioning

Coptis Japonica Root Extract

Skin Conditioning

Hydrolyzed Gardenia Florida Extract

Antioxidant
Antioxidant Icon

Paeonia Albiflora Flower Extract

Tonic

Hydrogenated Lecithin

Emulsifying
Helps hydrate Dry Skin Icon

Pelargonium Graveolens Flower Oil

Masking
Fragrance IconOil IconMay cause irritation IconEU Allergen Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Camellia Sinensis Seed Oil

Humectant
Oil IconHelps hydrate Dry Skin IconHelps reduce irritation IconNot safe for Fungal Acne Icon

Argania Spinosa Kernel Oil

Emollient
Oil IconHelps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots IconNot safe for Fungal Acne Icon

Palmitic Acid

Emollient
2 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Cetearyl Olivate

Not safe for Fungal Acne Icon

Sorbitan Olivate

Emulsifying
Not safe for Fungal Acne Icon

C12-16 Alcohols

Emollient

Behenyl Alcohol

Emollient
Fatty Alcohol Icon

Stearic Acid

Cleansing
2-3 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Microcrystalline Cellulose

Absorbent

Cetearyl Glucoside

Emulsifying

Ethylhexylglycerin

Skin Conditioning

C12-15 Alkyl Benzoate

Antimicrobial

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Polyglyceryl-10 Myristate

Skin Conditioning
Not safe for Fungal Acne Icon

Glyceryl Polymethacrylate

Cellulose Gum

Emulsion Stabilising
0 / 0

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Cholesterol

Emollient
0 / 0 Helps hydrate Dry Skin Icon

Fructooligosaccharides

Humectant
Helps hydrate Dry Skin Icon

Disodium EDTA

Beta-Glucan

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging IconGood for Scar Healing Icon

Carnosine

Skin Conditioning
Helps with Anti-Aging IconGood for Scar Healing Icon

Hydrolyzed Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Methylpropanediol

Solvent

Maltodextrin

Absorbent
Helps hydrate Dry Skin Icon

Guaiazulene

Antimicrobial
Fragrance Icon

Oligopeptide-1

Skin Conditioning
Peptide Icon

Arginine

Masking
Good for Scar Healing IconNot safe for Fungal Acne Icon

Carbomer

Emulsion Stabilising
1 / 0

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Dimethylsilanol Hyaluronate

Humectant

Hydrolyzed Sodium Hyaluronate

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Scar Healing Icon

Potassium Hyaluronate

Skin Conditioning

Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Sodium Hyaluronate Crosspolymer

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconGood for Scar Healing Icon

Hydroxypropyltrimonium Hyaluronate

Dimethiconol

Emollient
Silicon Icon

Sodium Acetylated Hyaluronate

Humectant
Hyaluronic Acid Icon

Citronellol

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Geraniol

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Linalool

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Water, Glycerin, Dipropylene Glycol, Cetearyl Alcohol, Caprylic/Capric Triglyceride, Methyl Trimethicone, Hydrogenated Polydecene, 1,2-Hexanediol, Phenyl Trimethicone, Vegetable Oil, Dimethicone/Vinyl Dimethicone Crosspolymer, Glyceryl Stearate Se, Artemisia Princeps Leaf Extract, Persea Gratissima Fruit Extract, Brassica Oleracea Acephala Leaf Extract, Laminaria Japonica Extract, Eclipta Prostrata Leaf Extract, Beta Vulgaris Root Extract, Chamaecyparis Obtusa Leaf Extract, Coptis Japonica Root Extract, Hydrolyzed Gardenia Florida Extract, Paeonia Albiflora Flower Extract, Hydrogenated Lecithin, Pelargonium Graveolens Flower Oil, Sodium Hyaluronate, Camellia Sinensis Seed Oil, Argania Spinosa Kernel Oil, Palmitic Acid, Cetearyl Olivate, Sorbitan Olivate, C12-16 Alcohols, Behenyl Alcohol, Stearic Acid, Microcrystalline Cellulose, Cetearyl Glucoside, Ethylhexylglycerin, C12-15 Alkyl Benzoate, Ceramide NP, Squalane, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Panthenol, Polyglyceryl-10 Myristate, Glyceryl Polymethacrylate, Cellulose Gum, Butylene Glycol, Cholesterol, Fructooligosaccharides, Disodium EDTA, Beta-Glucan, Carnosine, Hydrolyzed Hyaluronic Acid, Methylpropanediol, Maltodextrin, Guaiazulene, Oligopeptide-1, Arginine, Carbomer, Tocopherol, Dimethylsilanol Hyaluronate, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Hydroxypropyltrimonium Hyaluronate, Dimethiconol, Sodium Acetylated Hyaluronate, Citronellol, Geraniol, Linalool

AGE-R Collagen Booster Gel Serum

Water

Skin Conditioning

Methylpropanediol

Solvent

Glycereth-26

Humectant
0 / 0 Helps hydrate Dry Skin Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Masking, Skin Conditioning

Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.

As a cosmetic ingredient, Arginine has antioxidant properties and can also help repair damaged skin. This ingredient is derived either synthetically or from animals.

Arginine isn't fungal acne safe when used in the presence of other lipids (fats, fatty acids, oils, esters, etc). Oils and fats occur naturally within the skin, so take caution when using Arginine if you're prone to fungal acne.

Learn more about Arginine
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Masking, Skin Conditioning

This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride
Skin Conditioning

Ceramide NP is a type of ceramide.

Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.

Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.

If you would like to eat ceramides, sweet potatoes contain a small amount.

Read more about other common types of ceramides here:
Ceramide AP
Ceramide EOP

Learn more about Ceramide NP
Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Moisturising, Skin Conditioning

Hyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.

This ingredient helps hydrate, soothe, and protect the skin.

What makes hyaluronic acid so hydrating? It has the capacity to bind or hold large amounts of water.

Fun fact: It is already naturally found in our bodies, such as the fluids of our eyes and our joints.

Studies find this ingredient to have anti-inflammatory and anti-microbial properties. This can help speed up wound-healing.

Hyaluronic acid can be irritating if the molecule has a low-molecular weight, or if the molecules are small.

One study found low-molecular weight hyaluronic acid to be pro-inflammatory, meaning some people may experience irritation. This is because our bodies use hyaluronic acid in the wound-healing process to signal to our bodies, via irritation, that something needs healing.

The same study found high-molecular weight hyaluronic acid to be anti-inflammatory.

These are some other common types of Hyaluronic Acid:

Learn more about Hyaluronic Acid
Humectant, Skin Conditioning

Hydrolyzed Hyaluronic Acid is a form of hyaluronic acid. It is created by the hydrolysis of hyaluronic acid with a high molecular weight. Once created, Hydrolyzed Hyaluronic Acid has a low molecular weight.

Low molecular weight HA has been shown to hydrate and increase elasticity of the skin. Increasing elasticity is also associated with reduction of wrinkle depth.

One study found topical low molecular weight hyaluronic acid may be considered for the treatment of rosacea in the adult population. However, we always recommend speaking with a professional about your skin concerns.

Hyaluronic acids are a humectant. This means they draw moisture from the air. Hyaluronic acids help moisturize, soothe, and protect the skin.

Read more about other common forms of hyaluronic acid:

Learn more about Hydrolyzed Hyaluronic Acid
Skin Conditioning

This ingredient is created by putting sodium hyaluronate through hydrolysis.

You might know this as 'mini' or 'ultra low-molecular weight' hyaluronic acid. The small molecule size means it is able to travel deeper in the skin.

According to studies, low molecular-weight hyaluronic acid can:

One study from 2011 found ultra-low weight HA to show pro-inflammatory properties. Another study from 2022 found it to downregulate UV-B induced inflammation.

Hydrolysis is a process of changing a molecule using water or enzymes.

This ingredient is water-soluble.

Learn more about Hydrolyzed Sodium Hyaluronate

This form of hyaluronic acid is produced through fermentation.

According to a manufacturer, it has a positive charge by ionic binding to help moisturize and give hair a smooth feel. This is why you'll find this ingredient in shampoos and body washes.

Methylpropanediol is a synthetic solvent and humectant.

As a solvent, it helps dissolve other ingredients, helping to evenly distribute ingredients throughout the product. This ingredient has also been shown to have antimicrobial properties which makes it a preservative booster.

Methylpropanediol is able to add a bit of moisture to the skin. It also helps other ingredients be better absorbed into the skin, such as salicylic acid.

Learn more about Methylpropanediol

Sodium Acetylated Hyaluronate is a type of Hyaluronic Acid.

Hyaluronic Acids help moisturize, soothe, and protect the skin.

Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Humectant, Skin Conditioning

Sodium Hyaluronate Crosspolymer is a type of hyaluronic acid. In fact, it is modified version of hyaluronic acid.

The structure of Sodium Hyaluronate Crosspolymer allows it to stay in the skin's top layer for a longer period of time. This allows for even more hydration and humectant action than hyaluronic acid.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate Crosspolymer
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

303 Routines
37% use in am
63% use in pm
94% use every day
When to use See routines that use it ->
16 Routines
44% use in am
56% use in pm
81% use every day

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Dr. Althea 147 Barrier Cream 69 ingredients

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