Differin Adapalene Gel 0.1% Acne Treatment
Biretix Soothing Gel
Versus

Differin Adapalene Gel 0.1% Acne Treatment Versus Biretix Soothing Gel

Facial Treatment
General Moisturizer
American Brand United States
Spanish Brand Spain

Updated on February 18, 2025

Overview

Cool Features

They both contain retinoid

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, oily skin, reducing pores, scar healing and better texture

Free From

They both do not contain any silicones or sulfates

What's Inside

They both contain parabens

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

New Comparison

Ingredient Info

Click any item below to learn more and see relevant ingredients

Differin Adapalene Gel 0.1% Acne Treatment 8 ingredients

Biretix Soothing Gel 46 ingredients

What's inside

What's inside

At a glance

Click on any of the items below to learn more

Differin Adapalene Gel 0.1% Acne Treatment 8 ingredients

Biretix Soothing Gel 46 ingredients

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Adapalene Gel 0.1% Acne Treatment

Adapalene 0.1%

Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing IconHelps fight Acne IconMay worsen Rosacea Icon

Carbomer

Emulsion Stabilising
1 / 0

Disodium EDTA

Methylparaben

Preservative
0 / 0 Preservative IconParaben IconNon-Reef-Safe IconMay worsen Eczema Icon

Poloxamer 182

Emulsifying

Propylene Glycol

Humectant
0 / 0 Helps hydrate Dry Skin IconMay worsen Eczema IconMay worsen Rosacea Icon

Water

Skin Conditioning

Sodium Hydroxide

Buffering

Adapalene 0.1%, Carbomer, Disodium EDTA, Methylparaben, Poloxamer 182, Propylene Glycol, Water, Sodium Hydroxide

Soothing Gel

Water

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Emulsion Stabilising

Polysorbate 80

Emulsifying
0 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Hydrogenated Lecithin

Emulsifying
Helps hydrate Dry Skin Icon

Dimethyl Isosorbide

Solvent

Isohexadecane

Emollient

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Bisabolol

Masking
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Trehalose

Humectant
Helps hydrate Dry Skin Icon

Betaine

Humectant
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots Icon

Sodium PCA

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Urea

Buffering
Helps hydrate Dry Skin IconGood for Skin Texture IconMay worsen Eczema IconMay worsen Rosacea Icon

Palmitoyl Hydroxypropyltrimonium Amylopectin/Glycerin Crosspolymer

Skin Conditioning

Hydroxypinacolone Retinoate

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Aloe Barbadensis Extract

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Lecithin

Emollient
Helps hydrate Dry Skin Icon

Papain

Skin Conditioning
0 / 0

Retinol

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Dehydroacetic Acid

Preservative
Preservative Icon

Glucose

Humectant
Helps hydrate Dry Skin Icon

Glycine Soja Oil

Emollient
3 / 0 Oil IconHelps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Sorbitol

Humectant
0 / 0 Helps hydrate Dry Skin Icon

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Fructose

Humectant
Helps hydrate Dry Skin Icon

Ascorbyl Palmitate

Antioxidant
2 / 0 Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconNot safe for Fungal Acne Icon

Maltodextrin

Absorbent
Helps hydrate Dry Skin Icon

Glycine

Buffering
Helps hydrate Dry Skin Icon

Citric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Phenoxyethanol

Preservative
Preservative Icon

Lactic Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin IconMay worsen Eczema IconMay worsen Rosacea Icon

Sodium Hydroxide

Buffering

Potassium Hydroxide

Buffering

Hydrolyzed Wheat Protein

Skin Conditioning

Benzyl Alcohol

Perfuming
Alcohol IconFragrance IconPreservative IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Sodium Glutamate

Masking

Beta-Sitosterol

Emulsion Stabilising
Helps hydrate Dry Skin Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Malic Acid

Buffering
AHA IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Glycolic Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Tartaric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Lysine

Skin Conditioning

Methylparaben

Preservative
0 / 0 Preservative IconParaben IconNon-Reef-Safe IconMay worsen Eczema Icon

Ethylparaben

Preservative
Preservative IconParaben IconNon-Reef-Safe Icon

Butylparaben

Masking
Preservative IconParaben IconCan worsen Dry Skin IconNon-Reef-Safe IconMay worsen Eczema Icon

Water, Glycerin, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polysorbate 80, Hydrogenated Lecithin, Dimethyl Isosorbide, Isohexadecane, Tocopherol, Bisabolol, Trehalose, Betaine, Sodium PCA, Urea, Palmitoyl Hydroxypropyltrimonium Amylopectin/Glycerin Crosspolymer, Hydroxypinacolone Retinoate, Aloe Barbadensis Extract, Butylene Glycol, Lecithin, Papain, Retinol, Dehydroacetic Acid, Glucose, Glycine Soja Oil, Sorbitol, Polysorbate 20, Fructose, Ascorbyl Palmitate, Maltodextrin, Glycine, Citric Acid, Phenoxyethanol, Lactic Acid, Sodium Hydroxide, Potassium Hydroxide, Hydrolyzed Wheat Protein, Benzyl Alcohol, Sodium Glutamate, Beta-Sitosterol, Squalane, Malic Acid, Glycolic Acid, Tartaric Acid, Lysine, Methylparaben, Ethylparaben, Butylparaben

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Methylparaben
Preservative

Methylparaben is a preservative and is a paraben. It is used to prevent the growth of fungus, mold, and other harmful bacteria. Parabens are chemicals used as preservatives in both cosmetics and food.

Methylparaben can be synthetically created. It can also be found naturally in some fruits, such as blueberries.

Oftentimes, Methylparaben is combined with other parabens to help increase the shelf life.

The safety of Methylparaben is currently being studied. While ongoing studies are looking into the safety of parabens, the results have been very mixed. Some studies have not found Methylparaben to be harmful.

Learn more about Methylparaben
Sodium Hydroxide
Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Learn more about Sodium Hydroxide
Water
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

Ingredient Ratings

Here's what our community thinks of the ingredients in these products.

Adapalene Gel 0.1% Acne Treatment
10
10
10
liked
mixed
disliked
not rated
Unlock with Premium
Soothing Gel
10
10
10
liked
mixed
disliked
not rated
Unlock with Premium

When to use

Differin Adapalene Gel 0.1% Acne Treatment 8 ingredients

Biretix Soothing Gel 46 ingredients

4,200 Routines
8% use in am
92% use in pm
68% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Differin Adapalene Gel 0.1% Acne Treatment 8 ingredients

4.51
Overall rating
5
4
3
2
1
What people say
Works Well 54% Absorbs Well 51% No Scent 51%
See all reviews for Adapalene Gel 0.1% Acne Treatment

Biretix Soothing Gel 46 ingredients

No reviews yet

Be the first to review Soothing Gel

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