

Dermarium Quenching Queen
A serum with 47 ingredients, including PHA, hyaluronic acid, and peptides.
Overview
What it is
Serum with 47 ingredients that contains hyaluronic acid, peptides and PHA
Cool Features
It is reef safe
Suited For
It has ingredients that are good for anti aging, dry skin, brightening skin, sensitive skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates
Fun facts
Dermarium is from Vietnam.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Water
Skin ConditioningBifida Ferment Filtrate
Skin ConditioningPanthenol
Skin ConditioningPropanediol
SolventMethyl Gluceth-20
HumectantHydroxyethyl Urea
HumectantGlyceryl Glucoside
HumectantAlpha-Glucan Oligosaccharide
Cleansing1,2-Hexanediol
Skin ConditioningGlycerin
HumectantBeta-Glucan
Skin ConditioningSaccharide Isomerate
HumectantMadecassoside
AntioxidantCentella Asiatica Leaf Extract
Skin ConditioningAsiaticoside
AntioxidantEctoin
Skin ConditioningBetaine
HumectantSodium PCA
HumectantSodium Lactate
BufferingPCA
HumectantSerine
MaskingAlanine
MaskingGlycine
BufferingGlutamic Acid
HumectantLysine Hcl
Skin ConditioningHydrolyzed Wheat Protein
Skin ConditioningThreonine
Xanthan Gum
EmulsifyingCaprylyl Glycol
EmollientLactic Acid/Glycolic Acid Copolymer
Skin ConditioningGlyceryl Caprylate
EmollientPhenylpropanol
MaskingPolyvinyl Alcohol
Palmitoyl Sh-Heptapeptide-12 Sp
Skin ConditioningPalmitoyl Oligopeptide-78
Skin ConditioningPalmitoyl Sh-Octapeptide-24 Amide
Skin ConditioningHydrolyzed Hyaluronic Acid
HumectantSodium Hyaluronate
HumectantTetrasodium Glutamate Diacetate
Allantoin
Skin ConditioningHydroxyacetophenone
AntioxidantGluconolactone
Skin ConditioningArginine
MaskingProline
Skin ConditioningCitric Acid
BufferingSodium Citrate
BufferingSodium Hydroxide
BufferingWater, Bifida Ferment Filtrate, Panthenol, Propanediol, Methyl Gluceth-20, Hydroxyethyl Urea, Glyceryl Glucoside, Alpha-Glucan Oligosaccharide, 1,2-Hexanediol, Glycerin, Beta-Glucan, Saccharide Isomerate, Madecassoside, Centella Asiatica Leaf Extract, Asiaticoside, Ectoin, Betaine, Sodium PCA, Sodium Lactate, PCA, Serine, Alanine, Glycine, Glutamic Acid, Lysine Hcl, Hydrolyzed Wheat Protein, Threonine, Xanthan Gum, Caprylyl Glycol, Lactic Acid/Glycolic Acid Copolymer, Glyceryl Caprylate, Phenylpropanol, Polyvinyl Alcohol, Palmitoyl Sh-Heptapeptide-12 Sp, Palmitoyl Oligopeptide-78, Palmitoyl Sh-Octapeptide-24 Amide, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Tetrasodium Glutamate Diacetate, Allantoin, Hydroxyacetophenone, Gluconolactone, Arginine, Proline, Citric Acid, Sodium Citrate, Sodium Hydroxide
Key Ingredients
Benefits
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterBifida ferment filtrate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolPropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.ย
Itโs often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolMethyl Gluceth-20 is a humectant. Humectants help draw moisture from the air to your skin.
It is created by combining polyethylene glycol with glucose.
Glyceryl Glucoside is made from glycerol and glucose.
It is a humectant. Humectants help hydrate your skin by drawing moisture to it from the air.
Some foods that contain glyceryl glucoside include sake, miso, and wines.
Learn more about Glyceryl GlucosideAlpha-Glucan Oligosaccharide is a prebiotic. It prevents harmful bacteria from growing on skin by keeping the skin's microbiome in balance.
Another benefit of this ingredient is its antioxidant properties. Antioxidants protect our skin from oxidative damage.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.ย
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesย
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinBeta-Glucan is a polysaccharide. It can be derived from the cell walls of seaweed, oats, yeast, and fungi. It hydrates the skin and helps boost your skin's natural barrier.
As an antioxidant, beta-glucan helps fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.
Studies show this ingredient may be an effective wrinkle reducer as it can deeply penetrate into skin. It has also been show to help with wound healing.
Learn more about Beta-GlucanSaccharide Isomerate comes from sugars found in corn. It is a skin hydrator.
The structure of this ingredient can be altered to be more similar to the carbohydrates found in our skin. This ability to mimic our skin gives it hydrating properties.
Specifically, saccharide Isomerate is a humectant. Humectants draw moisture from the air to our skin.
Research shows Saccharide Isomerate to be an effective moisturizer.
Learn more about Saccharide IsomerateMadecassoside comes from the super popular skin-soothing ingredient, Centella asiatica. It is one of four active compounds found in the extract of Centella Asiatica.
Madecassoside has antioxidant, anti-inflammatory, and hydrating properties. It contains fatty acids, amino acids, beta-carotene, and phytochemicals.
One study found using Madecassoside with ascorbic acid helped reduce the signs of aging and improved skin hydration.
Learn more about MadecassosideCentella Asiatica Leaf Extract comes from the leaves of an herb plant native to Southeast Asia. Centella Asiatica is rich in antioxidants and amino acids. It can help reduce irritation and soothe the skin.
Many active components found in centella asiatica, such as Madecassic Acid and Asiaticoside, encourage the skin to naturally produce hyaluronic acid. This helps keep our skin hydrated. Many of these components also show antioxidant activity and may help reduce the signs of aging.
Research shows centella asiatica can help increase Type I collagen production by increasing fibroblast production. Fibroblast helps form connective tissue.
The combination of all these properties makes centella asiatica leaf extract effective at soothing the skin.
Other components of centella asiatica leaf extract include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.
Recent studies found madecassoside may help prevent damage from UV rays by preventing UV-induced inflammation. Further research is needed.
This plant has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.
Learn more about Centella Asiatica Leaf ExtractAsiaticoside comes from the super popular skin-soothing ingredient, Centella asiatica. It is one of four active compounds found in the extract of Centella Asiatica.
Asiaticoside is an antioxidant and helps with wound healing. It has been shown to increase antioxidant activity during the wound healing process.
Ectoin is a compound found naturally in some species of bacteria. It can be synthetically created for skincare use.
This ingredient is an osmolyte; Osmolytes help organisms survive osmotic shock (it protects them from extreme conditions). It does this by influencing the properties of biological fluids within cells.
When applied to the skin, ectoin helps bind water molecules to protect our skin. The water forms a sort of armor for the parts of our skin cells, enzymes, proteins, and more.
Besides this, ectoin has many uses in skincare:
A study from 2004 found ectoin to counteract the damage from UV-A exposure at different cell levels. It has also been shown to protect skin against both UV-A, UV-B rays, infrared light, and visible light.
Studies show ectoin to have dual-action pollution protection: first, it protects our skin from further pollution damage. Second, it helps repair damage from pollution.
In fact, ectoin has been shown to help with:
Fun fact: In the EU, ectoin is used in inhalation medication as an anti-pollution ingredient.
Ectoin is a highly stable ingredient. It has a wide pH range of 1-9. Light, oxygen, and temperature do not affect this ingredient.
Learn more about EctoinBetaine is a common humectant (a substance that promotes retention of moisture). It's known to be gentle on the skin and can help balance hydration.
This ingredient is best for improving hydration and soothing irritated skin. Studies also show it helps even out skin tone.
Fun fact: Betaine is naturally created in the skin and body. The kind found within cosmetic products can be either plant-derived or synthetic.
Learn more about BetaineSodium PCA is the sodium salt of pyroglutamic acid. It is naturally occurring in our skin's natural moisturizing factors where it works to maintain hydration.
The PCA stands for pyrrolidone carboxylic acid, a natural amino acid derivative.
This ingredient has skin conditioning, anti-inflammatory, and humectant properties. Humectants help hydrate your skin by drawing moisture from the air. This helps keep your skin moisturized.
Learn more about Sodium PCASodium Lactate is the sodium salt of lactic acid, an AHA. It is a humectant and sometimes used to adjust the pH of a product.
This ingredient is part of our skin's NMF, or natural moisturizing factor. Our NMF is essential for the hydration of our top skin layers and plasticity of skin. NMF also influences our skin's natural acid mantle and pH, which protects our skin from harmful bacteria.
High percentages of Sodium Lactate can have an exfoliating effect.
Fun fact: Sodium Lactate is produced from fermented sugar.
Learn more about Sodium LactatePCA is derived from amino acids and is naturally found in our skin's barrier.
As a humectant, PCA helps draw and hold moisture to the skin. Studies show it is effective at helping the skin stay hydrated long-term.
Serine is an amino acid naturally found in our body. Our bodies use amino acids to create protein.
Amino-acids help give keep our skin hydrated. They play an important role in the skin barrier, which keeps the skin plump and firm.
Serine is a non-essential amino acid, meaning we don't need to obtain it from eating foods.
Learn more about SerineAlanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin.
This ingredient is an amino acid that helps build proteins and moisturizes skin. It is already present in our skin as our bodies produce them naturally.
Glycine already plays a role in helping keep our skin moisturized as amino acids transport moisture throughout our skin.
As collagen is made up of glycine and other amino acids, it is believed glycine may help our skin produce more collagen.
Learn more about GlycineGlutamic Acid is an amino acid that is found in all living organisms. Our bodies use this to help nerve cells in the brain communicate with other cells.
In cosmetics, glutamic acid is a famous humectant. It draws water from the air to your skin, keeping your skin hydrated (like hyaluronic acid).
An in-vitro study from 2024 found glutamic acid to play a role in inhibiting inflammation and thus a potential skin-soothing ingredient.
Other studies show it to be have potential wound healing, skin barrier repair, and hair growth properties.
Glutamic acid has poor solubility in water and other solvents.
Learn more about Glutamic AcidLysine HCl is an alpha amino acid salt.
Our skin uses amino acids as a precursor for building protein, and therefore keratins, collagen and elastin.
We don't have a description for Hydrolyzed Wheat Protein yet.
Threonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.
Our skin uses threonine for creating collagen and elastin. Humans are not able to create threonine and must get it through eating foods such as fish, lentils, poultry, sesame seeds, and more.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumCaprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.
Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.
This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.
Learn more about Caprylyl GlycolThis ingredient is a combination of two AHAs, lactic acid and glycolic acid. It has exfoliating properties
Glyceryl Caprylate comes from glycerin and caprylic acid, a fatty acid from coconut. It has emollient and emulsifier properties.
As an emollient, it helps hydrate your skin. Emollients work by creating a barrier on your skin to trap moisture in, helping to keep your skin soft and smooth.
On the other hand, emulsifiers prevent ingredients (such as oil and water) from separating.
Learn more about Glyceryl CaprylatePhenylpropanol is a fragrance.
We don't have a description for Polyvinyl Alcohol yet.
Palmitoyl Sh-Heptapeptide-12 Sp is a peptide.
Palmitoyl Oligopeptide-78 isn't fungal acne safe and is a peptide.
Palmitoyl Sh-Octapeptide-24 Amide is a peptide.
Hydrolyzed Hyaluronic Acid is a form of hyaluronic acid. It is created by the hydrolysis of hyaluronic acid with a high molecular weight. Once created, Hydrolyzed Hyaluronic Acid has a low molecular weight.
Low molecular weight HA has been shown to hydrate and increase elasticity of the skin. Increasing elasticity is also associated with reduction of wrinkle depth.
One study found topical low molecular weight hyaluronic acid may be considered for the treatment of rosacea in the adult population. However, we always recommend speaking with a professional about your skin concerns.
Hyaluronic acids are a humectant. This means they draw moisture from the air. Hyaluronic acids help moisturize, soothe, and protect the skin.
Read more about other common forms of hyaluronic acid:
Learn more about Hydrolyzed Hyaluronic AcidSodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateTetrasodium Glutamate Diacetate is a chelating agent. Chelating agents help prevent metal ions from binding to other ingredients. This helps prevent unwanted effects and reactions from a product. These metal ions may come from water and are found in miniscule amounts.
Tetrasodium Glutamate Diacetate can also help other preservatives be more effective.
Allantoin plays a role in soothing and moisturizing the skin. Because of this, it is often added to products with strong active ingredients.
Some studies have shown this ingredient can promote wound healing with higher concentrations.
Allantoin is derived from the comfrey plant but produced synthetically for cosmetic products to ensure purity.
Learn more about AllantoinHydroxyacetophenone is antioxidant with skin conditioning and soothing properties. It also boosts the efficiency of preservatives.
This ingredient is not irritating or sensitizing.
Gluconolactone is a PHA. PHAs are a great gentle alternative to traditional AHAs.
When applied, Gluconolactone has the same affect on skin as AHAs such as lactic acid. It helps dissolve the dead skin cells in the top layer of your skin. This improves texture and brightens the skin.
PHAs are more gentle than AHAs due to their larger structure. They do not penetrate as deeply as AHAs and take a longer time to dissolve dead cells. Studies show PHAs do not cause as much irritation.
Gluconolactone has some interesting properties:
In a 2004 study, Gluconolactone was found to prevent UV damage in mouse skin cells and has not been found to increase sun sensitivity. However, we still recommend wearing SPF daily.
This ingredient is is an created by reacting gluconic acid with an alcohol.
Learn more about GluconolactoneArginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.
As a cosmetic ingredient, Arginine has antioxidant properties and can also help repair damaged skin. This ingredient is derived either synthetically or from animals.
Arginine isn't fungal acne safe when used in the presence of other lipids (fats, fatty acids, oils, esters, etc). Oils and fats occur naturally within the skin, so take caution when using Arginine if you're prone to fungal acne.
Learn more about ArginineProline is an amino-acid. It helps moisturize the skin and plays an important role in creating proteins.
Our skin uses proline as one of the building blocks for producing collagen.
In medicine, proline is used as an osmoprotectant. This means it helps prevent oxidative degradation in other drugs.
Our bodies are able to produce proline naturally, but certain conditions may inhibit this production. In that case, proline can be obtained from eating egg whites, soy protein, dairy products, asparagus, mushrooms, and seaweed.
Learn more about ProlineCitric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).
As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and even out skin tone.
If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.
Read more about some other popular AHA's here:
Learn more about Citric AcidSodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.
Its main functions are to maintain the pH of a product and neutralize metal ions.
The acidity of our skin is maintained by our glands and skin biome; normal pH level of skin is slightly acidic (~4.75-5.5).
Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.
Learn more about Sodium CitrateSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideReviews
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Where it's from
Dermarium is a Vietnamese brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about usยท Published August 28, 2025 • Added by betuskincare