Prequel Reactive Skin Solutions 5% Ectoin Cream Versus The INKEY List Ectoin Hydro-Barrier Serum
Updated on March 20, 2025
Overview
What they are
These products are both cruelty-free and reef safe . They have a total of 9 ingredients in common
Suited For
They're both likely to be good for dry skin, brightening skin, sensitive skin and scar healing
Free From
They both do not contain any harsh alcohols, common allergens, parabens or silicones
What's Inside
They both contain sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Prequel Reactive Skin Solutions 5% Ectoin Cream 19 ingredients
The INKEY List Ectoin Hydro-Barrier Serum 40 ingredients
About this product
About this product
At a glance
Click on any of the items below to learn more
Prequel Reactive Skin Solutions 5% Ectoin Cream 19 ingredients
The INKEY List Ectoin Hydro-Barrier Serum 40 ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterCetearyl alcohol is a mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is mainly used as an emulsifier. Emulsifiers help prevent the separation of oils and products. Due to its composition, it can also be used to thicken a product or help create foam.
Cetearyl alcohol is an emollient. Emollients help soothe and hydrate the skin by trapping moisture.
Studies show Cetearyl alcohol is non-toxic and non-irritating. The FDA allows products labeled "alcohol-free" to have fatty alcohols.
This ingredient is usually derived from plant oils such as palm, vegetable, or coconut oils. There is debate on whether this ingredient will cause acne.
Due to the fatty acid base, this ingredient may not be Malassezia folliculitis safe.
Learn more about Cetearyl AlcoholEctoin is a compound found naturally in some species of bacteria. It can be synthetically created for skincare use.
This ingredient is an osmolyte; Osmolytes help organisms survive osmotic shock (it protects them from extreme conditions). It does this by influencing the properties of biological fluids within cells.
When applied to the skin, ectoin helps bind water molecules to protect our skin. The water forms a sort of armor for the parts of our skin cells, enzymes, proteins, and more.
Besides this, ectoin has many uses in skincare:
A study from 2004 found ectoin to counteract the damage from UV-A exposure at different cell levels. It has also been shown to protect skin against both UV-A, UV-B rays, infrared light, and visible light.
Studies show ectoin to have dual-action pollution protection: first, it protects our skin from further pollution damage. Second, it helps repair damage from pollution.
In fact, ectoin has been shown to help with:
Fun fact: In the EU, ectoin is used in inhalation medication as an anti-pollution ingredient.
Ectoin is a highly stable ingredient. It has a wide pH range of 1-9. Light, oxygen, and temperature do not affect this ingredient.
Learn more about EctoinGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolPanthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolSodium Cetearyl Sulfate is a type of sulfate.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Ingredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Prequel Reactive Skin Solutions 5% Ectoin Cream 19 ingredients
The INKEY List Ectoin Hydro-Barrier Serum 40 ingredients

Reviews
Here's what our community thinks
Prequel Reactive Skin Solutions 5% Ectoin Cream 19 ingredients
The INKEY List Ectoin Hydro-Barrier Serum 40 ingredients
This is a really great product. Absorbs well, creates a really nice, but non-sticky protective layer that still allows others products to sink in. Super light weight and easy to spread. It feels quite unique and definitely something that stands out in my routine.