Versus

Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum Versus ZO Skin Health Wrinkle + Texture Repair

Serum
Facial Treatment
American Brand
American Brand

Updated on June 12, 2025

Overview

What they are

These products are both cruelty-free and reef safe . They have a total of 8 ingredients in common

Cool Features

They both contain exfoliants, retinoid, Vitamin C and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any harsh alcohols, parabens or sulfates

What's Inside

They both contain oils and silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Wrinkle + Texture Repair

Water

Skin Conditioning

Cetearyl Isononanoate

Emollient

Cyclopentasiloxane

Emollient
Silicon Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Masking, Skin Conditioning, Soothing

Bisabolol is famous for its skin soothing properties. It does this by blocking inflammatory signals, helping to reduce your body's reaction to irritation.

This ingredient also interferes with the process of hyperpigmentation. This can help with reducing dark spots and uneven tone.

Bisabolol is an antioxidant. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells. By fighting these free-radicals, Bisabolol may slow down signs of aging.

Studies have shown Bisabolol to have antimicrobial properties and may be a fungicide. These properties help preserve a product's shelf life.

All these properties makes bisabolol a great skin barrier helper ingredient.

Bisabolol also helps the absorption of other ingredients.

Note: Synthetic Bisabolol has been shown to be less effective.

Learn more about Bisabolol
Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol
Emollient, Skin Conditioning, Solvent

Cyclopentasiloxane, or D5, is a silicone used to improve texture of products and trap moisture.

D5 is considered lightweight and volatile. Volatile means it evaporates quickly after application. Once evaporated, D5 leaves a thin barrier that helps keep skin hydrated.

It is also an emollient. Emollients help soften the skin and prevent water loss. Silicones create a silky texture in products. D5 helps other ingredients become more spreadable.

Studies show D5 is safe to use in skincare products. We recommend speaking with a skincare professional if you have concerns.

Learn more about Cyclopentasiloxane
Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Emulsifying, Skin Conditioning, Solvent

Hexylene Glycol is a surfactant. Glycols are a class of alcohols. Hexylene Glycol is a surfactant and emulsifier.

As a surfactant, Hexylene Glycol helps gather dirt and oil on your skin to be washed away.

As an emulsifier, Hexylene Glycol helps keep water and oil together. This prevents them from separating in a product. Hexylene Glycol also thins out the texture of a product by lessening viscosity.

Hexylene Glycol has a small molecular weight.

Learn more about Hexylene Glycol
Emollient, Emulsifying, Skin Conditioning

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.

This ingredient has emollient and emulsifying properties.

As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.

As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.

This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.

Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.

We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.

Learn more about Lecithin
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Skin Conditioning

Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.

Why is retinol famous?

It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.

Retinol is proven to:

This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.

Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).

Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

We recommend speaking with a medical professional about using this ingredient during pregnancy.

Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.

Read about Tretinoin

Learn more about Retinol

When to use

26 Routines
15% use in am
85% use in pm
65% use every day
When to use See routines that use it ->
38 Routines
0% use in am
100% use in pm
45% use every day
When to use See routines that use it ->