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Product Comparison

Here's our complete breakdown comparing the ingredients, attributes, and more of NeoStrata Dermal Replenishment versus Mary Kay Oil Free Hydrating Gel .

Last updated on September 29, 2023. Published on December 09, 2023

Overview

What they are

These products are both general moisturizers. They have a total of 20 ingredients in common

Suited For

They're both likely to be good for dry skin, brightening skin and sensitive skin

Free From

They both do not contain any harsh alcohols, common allergens, oils or sulfates

What's Inside

They both contain silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that need an update? Let us know.

General Moisturizer

All-purpose moisturizers hydrate the top layer of skin cells.

General Moisturizer

All-purpose moisturizers hydrate the top layer of skin cells.

Price

Ingredient Info

Click any item below to learn more and view relevant ingredients.
alcohol-free
silicon-free
fragrance-free
sulfate-free
paraben-free
oil-free
fungal-acne safe
reef-safe
eu-allergen-free
vegan
cruelty-free
alcohol-free
silicon-free
fragrance-free
sulfate-free
paraben-free
oil-free
fungal-acne safe
reef-safe
eu-allergen-free
vegan
cruelty-free

At a glance

Click on any of the items below to learn more

Benefits

Hydrating (4)
Redness Reducing
Reduces Irritation
Brightening

Concerns

May Worsen Oily Skin (2)
Acne Trigger (2)
Eczema

Notable Ingredients

Chemical UV Filter
Vitamin E

Benefits

Hydrating (3)
Redness Reducing
Reduces Irritation
Brightening (2)

Concerns

May Worsen Oily Skin (2)
Eczema (3)
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Ingredients Compared

Ingredients that are highlighted in purple are present in both products.

Water • Dimethicone • Cyclopentasiloxane • Glycerin • Propylene Glycol • Cyclohexasiloxane • Betaine • Camellia Sinensis Extract • Algae Extract • Tocopheryl Acetate • Sodium PCA • Proline • Arginine • Glycine • Alanine • Lysine • Glutamic Acid • Serine • Threonine • Sorbitol • Butylene Glycol • Hydrogenated Polyisobutene • Glyceryl Polyacrylate • C13-14 Isoparaffin • Polyacrylamide • Peg-12 • Carbomer • Laureth-7 • Disodium EDTA • Benzophenone-4 • Triethanolamine • Phenoxyethanol • Methylparaben • DMDM Hydantoin • Basic Violet 2 • Curry Red

Ingredients Side-by-side

Ingredients that are highlighted in purple are present in both products.

Learn more about what what Com. / Irr. ratings are

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Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1
What it does: Skin Conditioning, Solvent
Community Rating: Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. Talk about multi-purpose! If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

NeoStrata Dermal Replenishment contains this as ingredient number 1.

Mary Kay Oil Free Hydrating Gel contains this as ingredient number 1.

2
What it does: Humectant, Skin Conditioning, Skin Protecting, Solvent
Community Rating: Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin

NeoStrata Dermal Replenishment contains this as ingredient number 2.

Mary Kay Oil Free Hydrating Gel contains this as ingredient number 4.

3
What it does: Emollient, Skin Conditioning, Solvent
Community Rating: Disliked

Cyclopentasiloxane is a silicone used to improve texture and trap moisture. An easier name for this is D5.

D5 is considered lightweight and volatile. Volatile means it evaporates quickly after application. Once evaporated, D5 leaves a thin barrier that helps keep skin hydrated.

D5 is an emollient. Emollients help soften the skin and prevent water loss. Silicones create a silky texture in products. D5 helps other ingredients become more spreadable.

Studies show D5 is safe to use in skincare products. We recommend speaking with a skincare professional if you have concerns.

Learn more about Cyclopentasiloxane

NeoStrata Dermal Replenishment contains this as ingredient number 13.

Mary Kay Oil Free Hydrating Gel contains this as ingredient number 3.

4
What it does: Emollient, Skin Conditioning, Solvent
Community Rating: Disliked

Cyclohexasiloxane is a type of silicone more commonly known as D6. It is an emollient and solvent.

Cyclohexasiloxane is used to evenly distribute ingredients throughout the product. When applied to the skin, Cyclohexasiloxane evaporates and leaves behind a silky feel.

As an emollient, it can help the skin feel soft and hydrated. It is also used to reduce frizz in hair products.

Learn more about Cyclohexasiloxane

NeoStrata Dermal Replenishment contains this as ingredient number 16.

Mary Kay Oil Free Hydrating Gel contains this as ingredient number 6.

5
What it does: Humectant, Skin Conditioning
Community Rating: Loved

Sodium PCA is the sodium salt of pyroglutamic acid and is naturally occurring on human skin.

The PCA stands for pyrrolidone carboxylic acid, a natural amino acid derivative.

Sodium PCA is a has conditioning, anti-inflammatory, and humectant properties. Humectants help hydrate your skin by drawing moisture from the air. This helps keep your skin moisturized.

Learn more about Sodium PCA

NeoStrata Dermal Replenishment contains this as ingredient number 20.

Mary Kay Oil Free Hydrating Gel contains this as ingredient number 11.

6
What it does: Masking, Skin Conditioning
Community Rating: Loved

Serine is an amino acid naturally found in our body. Our bodies use amino acids to create protein.

Amino-acids help give keep our skin hydrated. They play an important role in the skin barrier, which keeps the skin plump and firm.

Serine is a non-essential amino acid, meaning we don't need to obtain it from eating foods.

Learn more about Serine

NeoStrata Dermal Replenishment contains this as ingredient number 21.

Mary Kay Oil Free Hydrating Gel contains this as ingredient number 18.

7
What it does: Buffering, Skin Conditioning
Community Rating: Loved

Glycine is an amino acid that helps build proteins. It is already present in our skin as our bodies produce them naturally.

Glycine helps keep skin hydrated and reduce signs of aging. Amino acids help transport moisture throughout our skin; glycine already plays a role in helping keep our skin moisturized.

As collagen is made up of glycine and other amino acids, it is believed Glycine may help our skin produce more collagen. Collagen helps keep skin plump and firm.

Learn more about Glycine

NeoStrata Dermal Replenishment contains this as ingredient number 22.

Mary Kay Oil Free Hydrating Gel contains this as ingredient number 14.

8
What it does: Masking, Skin Conditioning
Community Rating: Loved

Alanine is an amino acid and is already found in the human body.

Alanine has antioxidant properties and can help with anti-aging.

Alanine is used by fibrous proteins such as collagen, elastin, and keratin. These three help make a strong skin barrier. Having a healthy skin barrier leads to more plump and youthful skin.

Learn more about Alanine

NeoStrata Dermal Replenishment contains this as ingredient number 23.

Mary Kay Oil Free Hydrating Gel contains this as ingredient number 15.

9
What it does: Skin Conditioning
Community Rating: Loved

Lysine is an essential amino acid. Your body is unable to produce it naturally and we mainly get lysine from food sources.

Our bodies use lysine for growth and tissue repair. The skin uses amino acids as a precursor for building protein, and therefore keratins, collagen and elastin.

NeoStrata Dermal Replenishment contains this as ingredient number 24.

Mary Kay Oil Free Hydrating Gel contains this as ingredient number 16.

10
What it does: Masking, Skin Conditioning
Community Rating: Mixed

Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.

As a cosmetic ingredient, Arginine has antioxidant properties and can also help repair damaged skin. This ingredient is derived either synthetically or from animals.

Arginine isn't fungal acne safe when used in the presence of other lipids (fats, fatty acids, oils, esters, etc). Oils and fats occur naturally within the skin, so take caution when using Arginine if you're prone to fungal acne.

Learn more about Arginine

NeoStrata Dermal Replenishment contains this as ingredient number 25.

Mary Kay Oil Free Hydrating Gel contains this as ingredient number 13.

11
What it does:
Community Rating: Loved

Threonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.

Threonine is vital for creating collagen and elastin. Collagen and elastin support youthful and firm skin. Our bodies decrease collagen production naturally with age.

Humans are not able to create threonine and must get it through eating foods such as fish, lentils, poultry, sesame seeds, and more.

Learn more about Threonine

NeoStrata Dermal Replenishment contains this as ingredient number 26.

Mary Kay Oil Free Hydrating Gel contains this as ingredient number 19.

12
What it does: Skin Conditioning
Community Rating: Loved

Proline is an amino-acid. It helps moisturize the skin and plays an important role in creating proteins.

Proline is one of the building blocks for producing collagen. As we age, our bodies produce less collagen. Collagen helps the skin look plump and firm.

In medicine, proline is used as an osmoprotectant. This means it helps prevent oxidative degradation in other drugs.

Our bodies are able to produce proline naturally, but certain conditions may inhibit this production. In that case, proline can be obtained from eating egg whites, soy protein, dairy products, asparagus, mushrooms, and seaweed.

Learn more about Proline

NeoStrata Dermal Replenishment contains this as ingredient number 27.

Mary Kay Oil Free Hydrating Gel contains this as ingredient number 12.

13
What it does: Humectant, Skin Conditioning, Solvent
Community Rating: Very Disliked

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

Another role of this ingredient is preventing a product from melting or freezing. Propylene glycol also adds antimicrobrial properties to a product, elongating product lifespan.

This ingredient is considered an organic alcohol and commonly added into both cosmetics and foods.

Those with sensitive skin or conditions may deliver a rash when using this ingredient.

Learn more about Propylene Glycol

NeoStrata Dermal Replenishment contains this as ingredient number 29.

Mary Kay Oil Free Hydrating Gel contains this as ingredient number 5.

14
What it does: Humectant, Skin Conditioning
Community Rating: Loved

Betaine is a common humectant (a substance that promotes retention of moisture). It's known to be gentle on the skin and can help balance hydration.

Betaine is best for improving hydration and soothing irritated skin. Studies show betaine may help with uneven skin tones.

Betaine is naturally created in the skin and body. The form found within cosmetic products can be either plant-dervied or synthetic.

Learn more about Betaine

NeoStrata Dermal Replenishment contains this as ingredient number 30.

Mary Kay Oil Free Hydrating Gel contains this as ingredient number 7.

15
What it does: Humectant, Masking, Skin Conditioning
Community Rating: Loved

Sorbitol is a sugar alcohol. It is a hydrating and moisturizing agent created from the reduction process of glucose.

Most sorbitol is usually made from potato starch. It is also found in fruits such as apples and pears.

As a humectant, Sorbitol helps draw water to the skin. This helps keep the skin hydrated. Sorbitol also helps create a thicker texture in products. You might find sorbitol in your toothpaste and other gels.

It is a non-irritating ingredient that is great for those with dry skin.

Sorbitol is a prebiotic. It helps promote the growth of healthy bacteria on your skin. The bacteria on your skin form a microbiome. This microbiome helps protect your skin from infection and harmful bacteria.

Learn more about Sorbitol

NeoStrata Dermal Replenishment contains this as ingredient number 31.

Mary Kay Oil Free Hydrating Gel contains this as ingredient number 20.

16
What it does: Humectant
Community Rating: Loved

Glutamic Acid is an amino acid that is found in all living organisms. Our bodies use this to help nerve cells in the brain communicate with other cells.

In cosmetics, glutamic acid is a famous humectant. It draws water from the air to your skin, keeping your skin hydrated (like hyaluronic acid).

An in-vitro study from 2024 found glutamic acid to play a role in inhibiting inflammation and thus a potential skin-soothing ingredient.

Other studies show it to be have potential wound healing, skin barrier repair, and hair growth properties.

Glutamic acid has poor solubility in water and other solvents.

Learn more about Glutamic Acid

NeoStrata Dermal Replenishment contains this as ingredient number 33.

Mary Kay Oil Free Hydrating Gel contains this as ingredient number 17.

17
What it does: Humectant, Masking, Skin Conditioning, Solvent
Community Rating: Mixed

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.

Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.

NeoStrata Dermal Replenishment contains this as ingredient number 34.

Mary Kay Oil Free Hydrating Gel contains this as ingredient number 21.

18
What it does: Emulsion Stabilising, Gel Forming
Community Rating: Disliked

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

Carbomer is commonly found in many types of cosmetics products. It is found to be safe in concentrations up to 15%. However, a high amount of carbomer can cause pilling or balling up of products. Most products contain 1% of less of carbomer.

NeoStrata Dermal Replenishment contains this as ingredient number 37.

Mary Kay Oil Free Hydrating Gel contains this as ingredient number 28.

19
What it does:
Community Rating: Disliked

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA

NeoStrata Dermal Replenishment contains this as ingredient number 40.

Mary Kay Oil Free Hydrating Gel contains this as ingredient number 30.

20
What it does: Preservative
Community Rating: Very Disliked

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent germ and microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

NeoStrata Dermal Replenishment contains this as ingredient number 44.

Mary Kay Oil Free Hydrating Gel contains this as ingredient number 33.

Here's what our community thinks of the ingredients in these two products.

37% are loved or liked
4% have mixed ratings
37% are disliked or very disliked
22% have no rating yet
42% are loved or liked
6% have mixed ratings
44% are disliked or very disliked
8% have no rating yet

Usage

Here's some more info on how this product is used by our community.

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