Versus

Medik8 Crystal Retinal - 10 Versus Differin Adapalene Gel 0.1% Acne Treatment

Serum
Facial Treatment
British Brand
American Brand

Updated on June 18, 2025

Overview

Cool Features

They both contain retinoid

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, oily skin, reducing pores, scar healing and better texture

Free From

They both do not contain any harsh alcohols, silicones or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

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What's inside (and what isn't)

What's inside (and what isn't)

At a glance

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Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Crystal Retinal

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

71 Routines
1% use in am
99% use in pm
76% use every day
When to use See routines that use it ->
3,949 Routines
7% use in am
93% use in pm
68% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Medik8 Crystal Retinal 41 ingredients

4.60
Overall rating
5
4
3
2
1
What people say
Expensive 60% Absorbs Well 40% Broke Me Out 40%
4.56
Overall rating
5
4
3
2
1
What people say
Works Well 56% Absorbs Well 53% No Scent 53%