MediCube Age-R Glutathione Glow Serum Versus Elizavecca Witch Piggy Hell Pore Control Hyaluronic Acid 97%
This anti-aging serum is formulated around Niacinamide and Glutathione to soften the look of wrinkles and brighten dull-looking skin.
This hydrating treatment is formulated around Sodium Hyaluronate and Niacinamide to hydrate skin and refine the look of pores.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
HumectantPEG-8
HumectantNiacinamide
SmoothingButylene Glycol
HumectantMethylpropanediol
Solvent1,2-Hexanediol
Skin ConditioningMethyl Gluceth-20
HumectantGlycereth-26
HumectantBis-PEG-18 Methyl Ether Dimethyl Silane
EmollientBetaine
HumectantCarbomer
Emulsion StabilisingDiphenyl Dimethicone
EmollientTromethamine
BufferingTriethylhexanoin
MaskingEthylhexylglycerin
Skin ConditioningC12-14 Alketh-12
EmulsifyingParfum
MaskingGlutathione
Xanthan Gum
EmulsifyingHydrogenated Lecithin
EmulsifyingAdenosine
Skin ConditioningCoptis Japonica Extract
AntimicrobialPolyglyceryl-10 Oleate
Skin ConditioningDisodium EDTA
ChelatingSaccharide Hydrolysate
HumectantPolyglyceryl-10 Laurate
Skin ConditioningPanthenol
Skin ConditioningCollagen
MoisturisingTheobroma Cacao Seed Extract
AntioxidantDextrin
AbsorbentSodium Hyaluronate
HumectantStellaria Media Extract
Skin ConditioningSorbitan Laurate
EmulsifyingPrunella Vulgaris Extract
AntioxidantLactobacillus Ferment
Skin ConditioningFucus Vesiculosus Extract
EmollientHydroxyethylcellulose
Emulsion StabilisingAcetyl Dipeptide-1 Cetyl Ester
Skin ConditioningLycopodium Clavatum Extract
Skin ConditioningEquisetum Arvense Extract
AstringentCaprylyl Glycol
EmollientHyaluronic Acid
HumectantPalmitoyl Tripeptide-5
Skin ConditioningSodium Hyaluronate Crosspolymer
HumectantHydrolyzed Sodium Hyaluronate
Skin ConditioningHydrolyzed Hyaluronic Acid
HumectantAcetyl Octapeptide-3
HumectantSodium Acetylated Hyaluronate
HumectantHydroxypropyltrimonium Hyaluronate
Hydrolyzed Keratin
HumectantHydrolyzed Collagen
EmollientHydrolyzed Silk
HumectantWater, Glycerin, PEG-8, Niacinamide, Butylene Glycol, Methylpropanediol, 1,2-Hexanediol, Methyl Gluceth-20, Glycereth-26, Bis-PEG-18 Methyl Ether Dimethyl Silane, Betaine, Carbomer, Diphenyl Dimethicone, Tromethamine, Triethylhexanoin, Ethylhexylglycerin, C12-14 Alketh-12, Parfum, Glutathione, Xanthan Gum, Hydrogenated Lecithin, Adenosine, Coptis Japonica Extract, Polyglyceryl-10 Oleate, Disodium EDTA, Saccharide Hydrolysate, Polyglyceryl-10 Laurate, Panthenol, Collagen, Theobroma Cacao Seed Extract, Dextrin, Sodium Hyaluronate, Stellaria Media Extract, Sorbitan Laurate, Prunella Vulgaris Extract, Lactobacillus Ferment, Fucus Vesiculosus Extract, Hydroxyethylcellulose, Acetyl Dipeptide-1 Cetyl Ester, Lycopodium Clavatum Extract, Equisetum Arvense Extract, Caprylyl Glycol, Hyaluronic Acid, Palmitoyl Tripeptide-5, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Acetyl Octapeptide-3, Sodium Acetylated Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Hydrolyzed Keratin, Hydrolyzed Collagen, Hydrolyzed Silk
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Learn more about AdenosineCarbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Learn more about CarbomerNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideParfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium Hyaluronate