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Updated on February 15, 2024

Overview

What they are

These products are both cruelty-free and reef safe . They have a total of 6 ingredients in common

Cool Features

They both contain hyaluronic acid and niacinamide

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores and dark spots

Free From

They both do not contain any harsh alcohols, parabens, silicones or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

ma:nyo Bifida Complex Ampoule
ma:nyo Bifida Complex Ampoule
Ampoule
Korean Brand South Korea
ma:nyo Bifida Biome Concentrate Serum

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Notable Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Bifida Complex Ampoule
Bifida Ferment Lysate Skin Conditioning
Helps hydrate Dry Skin Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.

Lactobacillus/Pumpkin Fruit Ferment Filtrate Skin Conditioning

We don't have a description for Lactobacillus/Pumpkin Fruit Ferment Filtrate.

Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Acetyl Hexapeptide-8 Humectant, Skin Conditioning
Peptide Icon
PeptidePeptide Icon

Acetyl Hexapeptide-8 is a peptide. A common name for this peptide is Argireline.

Aureobasidium Pullulans Ferment Skin Conditioning

We don't have a description for Aureobasidium Pullulans Ferment.

Hydrolyzed Algin

We don't have a description for Hydrolyzed Algin.

Caffeine Skin Conditioning

Caffeine is most associated with coffee, tea, and cacao. In skincare, it helps with calming inflammation and anti-aging.

Panax Ginseng Root Extract Emollient, Skin Protecting, Tonic
Helps hydrate Dry Skin IconHelps reduce Skin Redness Icon
2 Benefits

Panax Ginseng Root is a popular herb from Asia. This root contains antioxidants, favonoids, and vitamins B12 and D.

Panax Ginseng Callus Culture Extract Skin Conditioning

This ingredient comes from the callus cells of ginseng.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Epigallocatechin Gallate Antioxidant
Antioxidant Icon
AntioxidantAntioxidant Icon

EGCG is most famous for being found in green tea. It is a type of catechin, a potent antioxidant.

Zanthoxylum Piperitum Fruit Extract Skin Conditioning

Zanthoxylum Piperitum Fruit Extract comes from the Japanese Pepper, also known as the Prickly Ash. This plant is native to the Korean peninsula and Japan.

Pulsatilla Koreana Extract Skin Conditioning

Pulsatilla Koreana Extract comes from the Korean pasque flower. This flower is used in traditional Korean medicine.

Unknown Full details ->
Usnea Barbata Extract

We don't have a description for Usnea Barbata Extract.

Unknown Full details ->
Copper Tripeptide-1 Skin Conditioning
Peptide IconHelps with Anti-Aging Icon
PeptidePeptide Icon Helps with Anti-AgingHelps with Anti-Aging Icon

Copper Tripeptide-1 is a peptide naturally found in body fluids. Peptides are building blocks for protein.

Physalis Alkekengi Fruit Extract Skin Conditioning

We don't have a description for Physalis Alkekengi Fruit Extract.

Unknown Full details ->
Methyl Gluceth-20 Humectant, Moisturising

Methyl Gluceth-20 is a humectant. Humectants help draw moisture from the air to your skin.

Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Adenosine Skin Conditioning
Helps with Anti-Aging IconGood for Scar Healing Icon
2 Benefits

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Bifida Biome Concentrate Serum
Bifida Ferment Lysate Skin Conditioning
Helps hydrate Dry Skin Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Dipropylene Glycol Masking, Solvent

Dipropylene Glycol is a synthetically created stabilizer and solvent. It is a part of the glycol class in the alcohol family.

Disliked Full details ->
Propanediol Solvent

Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.

1,2-Hexanediol Skin Conditioning, Solvent

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Rosa Damascena Flower Water Masking, Skin Conditioning, Skin Protecting

Rosa Damascena Flower Water comes from the Damask rose. It is a dilluted version of the Rose Essential oil.

Panthenol Skin Conditioning
0 / 0 Helps reduce irritation Icon
Helps reduce irritationHelps reduce irritation Icon

Panthenol is a common ingredient that helps hydrate and soothe the skin. It can be found naturally in our skin and hair.

0 Com. / 0 Irr.
Cutibacterium Granulosum Ferment Extract Filtrate Emollient, Skin Conditioning

We don't have a description for Cutibacterium Granulosum Ferment Extract Filtrate.

Unknown Full details ->
Phytosphingosine Skin Conditioning

Phytosphingosine is a phospholipid naturally found in our skin. It helps moisturize, soothe, and protect skin.

Acetylphytosphingosine Skin Conditioning

We don't have a description for Acetylphytosphingosine.

Unknown Full details ->
Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Hydroxypropyltrimonium Hyaluronate

This form of hyaluronic acid is produced through fermentation.

Hydrolyzed Hyaluronic Acid Humectant, Skin Conditioning
Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Hydrolyzed Hyaluronic Acid is a form of hyaluronic acid. It is created by the hydrolysis of hyaluronic acid with a high molecular weight. Once created, Hydrolyzed Hyaluronic Acid has a low molecular weight.

Sodium Acetylated Hyaluronate Humectant
Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Acetylated Hyaluronate is a type of Hyaluronic Acid.

Sodium Hyaluronate Crosspolymer Humectant, Skin Conditioning
Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate Crosspolymer is a type of hyaluronic acid. In fact, it is modified version of hyaluronic acid.

Hydrolyzed Sodium Hyaluronate Skin Conditioning

This ingredient is created by putting sodium hyaluronate through hydrolysis.

Hyaluronic Acid Humectant, Moisturising, Skin Conditioning
Hyaluronic Acid IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation Icon
Hyaluronic AcidHyaluronic Acid Icon 4 Benefits May cause irritationMay cause irritation Icon

Hyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.

Potassium Hyaluronate Skin Conditioning

We don't have a description for Potassium Hyaluronate.

Caprylic/Capric Triglyceride Masking, Skin Conditioning

Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

Glyceryl Acrylate/Acrylic Acid Copolymer Humectant

Glyceryl Acrylate/Acrylic Acid Copolymer is made up of glycerin and polyacrylic acid. It helps hydrate your skin as a humectant.

C10-30 Alkyl Acrylate

We don't have a description for C10-30 Alkyl Acrylate.

Unknown Full details ->
Peg-Crosspolymer

We don't have a description for Peg-Crosspolymer.

Unknown Full details ->
Adenosine Skin Conditioning
Helps with Anti-Aging IconGood for Scar Healing Icon
2 Benefits

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Squalane Emollient, Skin Conditioning
1 / 0 Helps hydrate Dry Skin Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

1 Com. / 0 Irr.
Polyglyceryl-10 Laurate Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polyglyceryl-10 Laurate is an ester of lauric acid and Polyglycerin-10.

Very Disliked Full details ->
Polyglyceryl-10 Myristate Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polyglyceryl-10 Myristate isn't fungal acne safe.

Very Disliked Full details ->
Ceramide NP Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon
CeramideCeramide Icon 4 Benefits

Ceramide NP is a type of ceramide.

Ceramide Ns Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon
CeramideCeramide Icon 4 Benefits

Ceramide NS is a type of Ceramide. Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.

Ceramide AP Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon
CeramideCeramide Icon 4 Benefits

Ceramide AP is a type of Ceramide.

Ceramide EOP Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon
CeramideCeramide Icon 4 Benefits

Ceramide EOP is a type of Ceramide.

Cholesterol Emollient, Emulsifying, Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness Icon
2 Benefits

Cholesterol is a class of organic molecules called lipids. It helps hydrate your skin and is essential to having a healthy skin barrier.

0 Com. / 0 Irr.
Centella Asiatica Leaf Water Skin Conditioning
Helps reduce Skin Redness Icon
Helps reduce Skin RednessHelps reduce Skin Redness Icon

Centella Asiatica Leaf Water is created by distilling centella asiatica leaves. Centella Asiatica is a herb native to Southeast Asia.

Camellia Sinensis Leaf Extract Antimicrobial, Antioxidant, Astringent
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconHelps fight Acne Icon
AntioxidantAntioxidant Icon 5 Benefits

Camellia Sinensis Leaf Extract is derived from the leaves of the tea plant. Black tea, green tea, and oolong tea are all harvested from this plant.

Olea Europaea Fruit Oil Masking, Perfuming, Skin Conditioning
0-2 / 0 Fragrance IconOil IconNot safe for Fungal Acne Icon
FragranceFragrance Icon OilOil Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Olea Europaea Fruit Oil is the fixed oil obtained from the ripe fruit of the Olive. In other words - olive oil.

0-2 Com. / 0 Irr.
Very Disliked Full details ->
Butyrospermum Parkii Butter Skin Conditioning
Helps hydrate Dry Skin IconMay worsen Oily Skin IconNot safe for Fungal Acne Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon 2 Concerns

Butyrospermum Parkii Butter is a plant lipid from the fruit of the Shea Tree. It is an effective skin hydrator and emollient.

Very Disliked Full details ->
Hydrogenated Lecithin Emulsifying, Skin Conditioning

Hydrogenated Lecithin is created from the hydrogenation of lecithin. Hydrogenation is a chemical reaction between molecule hydrogen and another element.

Polyglyceryl-4 Oleate Emulsifying
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polyglyceryl-4 Oleate isn't fungal acne safe.

Unknown Full details ->
Ethylhexyl Olivate Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Ethylhexyl Olivate isn't fungal acne safe.

Very Disliked Full details ->
Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Arginine Masking, Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.

Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Portulaca Oleracea Extract Skin Conditioning

Portulaca Oleracea Extract is an extract of the whole plant of the Purslane, Portulaca oleracea L., Portulacaceae. It has anti-inflammatory, antioxidant, and hydrating properties.

Linalool Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon
FragranceFragrance Icon 2 Concerns

Linalool is a fragrance and helps add scent to products. It's derived from common plants such as cinnamon, mint, citrus, and lavender.

Very Disliked Full details ->
Benzyl Salicylate Perfuming, UV Absorber
Fragrance IconEU Allergen Icon
FragranceFragrance Icon EU AllergenEU Allergen Icon

Benzyl Salicylate is a solvent and fragrance additive. It is an ester of benzyl alcohol and salicylic acid. This ingredient can be naturally found in some plants and plant extracts.

Very Disliked Full details ->
Parfum Masking, Perfuming
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon
FragranceFragrance Icon 2 Concerns

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Very Disliked Full details ->

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning
Liked

Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.

Having a healthy microbiome helps protect our skin against infection. It also helps our skin stay hydrated and healthy.

Studies also show this ingredient to be a promising soothing ingredient for sensitive skin.

Learn more about Bifida Ferment Lysate
Smoothing
Loved

Niacinamide has emerged as an all-star ingredient due to its many benefits.

It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Learn more about Niacinamide
Humectant, Masking, Skin Conditioning
Mixed

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.

Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.

Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Skin Conditioning
Loved

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Skin Conditioning
Loved

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Learn more about Adenosine

Ingredient Ratings

Here's what our community thinks of the ingredients in these two products.

Bifida Complex Ampoule
14
3
3
liked
mixed
disliked
not rated
Bifida Biome Concentrate Serum
26
7
11
5
liked
mixed
disliked
not rated

When to use

109 Routines
40% use in am
60% use in pm
94% use every day
When to use See routines that use it ->
7 Routines
43% use in am
57% use in pm
100% use every day

Reviews

Here's what our community thinks

ma:nyo Bifida Complex Ampoule 20 ingredients

5.0 /5
from 2 ratings
Hydrating (2) No Scent (2) Works Well (2)
nja's avatar

nja

5 months ago · Sensitive Skin
Review

This is some pretty amazing stuff, it's what makes my skin glow! Bifida is great for the skin barrier and pumpkin fruit ferment filtrate has...

This is some pretty amazing stuff, it's what makes my skin glow! Bifida is great for the skin barrier and pumpkin fruit ferment filtrate has exfoliation properties. It also has peptides and niacinamide. Basically te entire INCI is amazing and it's also FA safe. The other version - Bifida BIOME Complex Ampoule - is *not* FA safe but it's very easy to get them mixed up because they look identical.
This ampoule exfoliates the skin and quite effectively, at least in my experience! So if you have very sensitive skin or are using any actives, keep that in mind. My skin gets a little flushed with this but I am using tretinoin. For now I use it once a week but when my skin gets totally used to tret, I plan on using it more because I love it!! It is kind of oily on the skin but it doesn't bother me when it works so well. The glow it gives is unmached!!

ReganAllen_429's avatar

ReganAllen_429

13 hours ago · Combination Skin
Review

So I have oily, sensitive, and acne prone skin and let me just say—this serum is absolutely incredible! My skin is so finicky about products and...

So I have oily, sensitive, and acne prone skin and let me just say—this serum is absolutely incredible! My skin is so finicky about products and ingredients that normally work wonders for others. So, when I heard the positive reviews from others about this product I was prepared for it to be yet another flop…But THIS serum omg! It’s outstanding. I notice my skin is less red after using this, my pimples decrease, AND I swear it helps sooth and lessen my hormonal acne. 10/10 highly recommend!

ma:nyo Bifida Biome Concentrate Serum 49 ingredients

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