La Roche-Posay Anthelios UVMune 400 Oil Control Fluid SPF 50+ Versus Cetaphil Pro Acne Prone Oil-Free Moisturising Lotion SPF 25
This chemical sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50.
This oil-control day moisturizer is formulated around Hydroxypalmitoyl Sphinganine and Zinc Gluconate to balance excess oil and clear breakouts.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningAlcohol Denat.
AntimicrobialTriethyl Citrate
MaskingDiisopropyl Sebacate
EmollientSilica
AbrasiveBis-Ethylhexyloxyphenol Methoxyphenyl Triazine
UV AbsorberEthylhexyl Salicylate
UV AbsorberEthylhexyl Triazone
UV AbsorberButyl Methoxydibenzoylmethane
UV AbsorberGlycerin
HumectantPropanediol
SolventC12-22 Alkyl Acrylate/Hydroxyethylacrylate Copolymer
StabilisingC12-15 Alkyl Benzoate
AntimicrobialSodium Citrate
BufferingMethoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate
StabilisingPerlite
AbsorbentTocopherol
AntioxidantCaprylic/Capric Triglyceride
MaskingAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingBixa Orellana Seed Extract
MaskingCaprylyl Glycol
EmollientCitric Acid
BufferingDiethylamino Hydroxybenzoyl Hexyl Benzoate
UV FilterDrometrizole Trisiloxane
UV AbsorberHydroxyacetophenone
AntioxidantHydroxyethylcellulose
Emulsion StabilisingMaltodextrin
AbsorbentPentylene Glycol
Skin ConditioningSilica Silylate
EmollientTerephthalylidene Dicamphor Sulfonic Acid
UV AbsorberTriethanolamine
BufferingTrisodium Ethylenediamine Disuccinate
Zinc PCA
HumectantParfum
MaskingWater, Alcohol Denat., Triethyl Citrate, Diisopropyl Sebacate, Silica, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Ethylhexyl Salicylate, Ethylhexyl Triazone, Butyl Methoxydibenzoylmethane, Glycerin, Propanediol, C12-22 Alkyl Acrylate/Hydroxyethylacrylate Copolymer, C12-15 Alkyl Benzoate, Sodium Citrate, Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate, Perlite, Tocopherol, Caprylic/Capric Triglyceride, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Bixa Orellana Seed Extract, Caprylyl Glycol, Citric Acid, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Drometrizole Trisiloxane, Hydroxyacetophenone, Hydroxyethylcellulose, Maltodextrin, Pentylene Glycol, Silica Silylate, Terephthalylidene Dicamphor Sulfonic Acid, Triethanolamine, Trisodium Ethylenediamine Disuccinate, Zinc PCA, Parfum
Water
Skin ConditioningOctocrylene
UV AbsorberIsopropyl Lauroyl Sarcosinate
Skin ConditioningEthylhexyl Salicylate
UV AbsorberGlycerin
HumectantDimethicone
EmollientButyl Methoxydibenzoylmethane
UV AbsorberDiisopropyl Sebacate
EmollientSucrose Tristearate
EmollientAluminum Starch Octenylsuccinate
AbsorbentSilica
AbrasivePolymethyl Methacrylate
Polysorbate 61
EmulsifyingPentylene Glycol
Skin ConditioningAllantoin
Skin ConditioningCaprylyl Glycol
EmollientCarbomer
Emulsion StabilisingDimethiconol
EmollientDisodium EDTA
Glycyrrhetinic Acid
Skin ConditioningHydroxypalmitoyl Sphinganine
Skin ConditioningPanthenol
Skin ConditioningPhenoxyethanol
PreservativePotassium Sorbate
PreservativeSodium Stearoyl Glutamate
CleansingTocopheryl Acetate
AntioxidantTriethanolamine
BufferingXanthan Gum
EmulsifyingZinc Gluconate
Skin ConditioningWater, Octocrylene, Isopropyl Lauroyl Sarcosinate, Ethylhexyl Salicylate, Glycerin, Dimethicone, Butyl Methoxydibenzoylmethane, Diisopropyl Sebacate, Sucrose Tristearate, Aluminum Starch Octenylsuccinate, Silica, Polymethyl Methacrylate, Polysorbate 61, Pentylene Glycol, Allantoin, Caprylyl Glycol, Carbomer, Dimethiconol, Disodium EDTA, Glycyrrhetinic Acid, Hydroxypalmitoyl Sphinganine, Panthenol, Phenoxyethanol, Potassium Sorbate, Sodium Stearoyl Glutamate, Tocopheryl Acetate, Triethanolamine, Xanthan Gum, Zinc Gluconate
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Also known as Avobenzone, this ingredient is an oil-soluble used to absorb the full spectrum of UVA rays (peak 357 nm).
It's one of the most effective UVA filters available but has a major caveat of photostability: avobenzone is susceptible to photodegradation.
This means it can lose efficacy when exposed to sunlight without the help of a stabilizing agent.
Studies show antioxidants (like vitamin E or vitamin C) and some UV filters (like octocrylene and Tinosorb S) can meaningfully improve its stability in a formulation.
The maximum allowable concentration according to regulation is 3% in the US + Canada, and 5% in the EU, Australia, China, Korea, and ASEAN countries.
It has a well-support safety profile: a comprehensive 2025 review found minimal toxicity with no evidence of carcinogenicity.
Overall, avobenzone is a safe and regulated ingredient used in sunscreen for over 40 years.
Learn more about Butyl MethoxydibenzoylmethaneCaprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolWe don't have a description for Diisopropyl Sebacate yet.
Ethylhexyl Salicylate (also called Octisalate or Octyl Salicylate) is an oil-soluble organic UV filter that's been used in sunscreen since the 1950's.
It absorbs UVB light in the 280-320 nm range with a peak absorbance around 306 nm.
You'll often see it paired with other UV filters to boost overall SPF because octisalate is a fairly week filter on its own.
The reason you'll see it so often is because it can help solubilize and stabilize the trickier filters like oxybenzone and avobenzone.
Unlike these filters, octisalate has pretty good photostability and doesn't create skin-damaging free radicals when exposed to sunlight.
The fatty-alcohol part of the molecule also gives it a light, emollient feel so it doubles as a nice texture enhancer.
Usage levels vary around the world:
Safety-wise, this ingredient has a pretty reassuring track record. The EU's Scientific Committee on Consumer Products (SCCP) found very low skin penetration in human skin tests and negative results for irritation, phototoxicity, and photoallergy.
The real-world allergy risk is pretty low too; a 2012 European study of 1,031 people recorded only 2 reactions to it (a rate of 0.19%).
You might have seen scary headlines about sunscreen getting into your blood.
In 2019, the FDA found that several chemical filters can absorb through the skin and show up in the bloodstream at small but measurable levels.
Here's the important part: these tiny levels are just a cutoff the FDA uses to decide which ingredients need more testing and doesn't mean anything harmful was found.
The researchers were clear that the results are no reason to stop wearing sunscreen.
Learn more about Ethylhexyl SalicylateGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Learn more about Pentylene GlycolSilica, also known as silicon dioxide, is a naturally occurring mineral. It is used as a fine, spherical, and porous powder in cosmetics.
Though it has exfoliant properties, the function of silica varies depending on the product.
The unique structure of silica enhances the spreadability and adds smoothness, making it a great texture enhancer.
It is also used as an active carrier, emulsifier, and mattifier due to its ability to absorb excess oil.
In some products, tiny microneedles called spicules are made from silica or hydrolyzed sponge. When you rub them in, they lightly polish away dead skin layers and enhance the penetration of active ingredients.
Learn more about SilicaTriethanolamine (TEA) is an emulsifier and pH adjuster. It is created using ethylene oxide and ammonia. This gives Triethanolamine a nitrogen core and a similar scent to ammonia.
As an emulsifier, it prevents ingredients from separating and enhances texture by adding volume to a product.
PH adjusters are common in cosmetic products. The pH of a product can affect the effectiveness of other ingredients. A product with a high pH may also irritate the skin.
If you are looking for the tea leaf ingredient, click here.
Learn more about TriethanolamineWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water