Isispharma Ruboril Metroruboril A.Z Versus Dermatica Custom Formula (Ivermectin 1%, Metronidazole 0.75%, Niacinamide 4%)
Updated on October 22, 2023
Overview
What they are
These products are both reef safe . They have a total of 4 ingredients in common
Cool Features
They both contain niacinamide
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots
Free From
They both do not contain any harsh alcohols, common allergens, oils, parabens or sulfates
What's Inside
They both contain silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Isispharma Ruboril Metroruboril A.Z 28 ingredients
Dermatica Custom Formula (Ivermectin 1%, Metronidazole 0.75%, Niacinamide 4%) 28 ingredients
About this product
About this product
At a glance
Click on any of the items below to learn more
Isispharma Ruboril Metroruboril A.Z 28 ingredients
Dermatica Custom Formula (Ivermectin 1%, Metronidazole 0.75%, Niacinamide 4%) 28 ingredients
Key Ingredients
Benefits
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningAzelaic Acid
Buffering
Betaine
Humectant
Caprylic/Capric Triglyceride
MaskingGlycerin
Humectant
Butylene Glycol
Humectant
Pentylene Glycol
Skin ConditioningVinyl Dimethicone/Methicone Silsesquioxane Crosspolymer
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingLauryl Glucoside
CleansingPolyglyceryl-2 Dipolyhydroxystearate
Skin Conditioning
Glycyrrhetinic Acid
Skin ConditioningNiacinamide
Smoothing
Ethylhexylglycerin
Skin ConditioningPanthenol
Skin Conditioning
Sclerotium Gum
Emulsion StabilisingChlorphenesin
Antimicrobial
Escin
TonicO-Cymen-5-Ol
Antimicrobial
Polysorbate 60
Emulsifying
Sorbitan Isostearate
Emulsifying
Ruscus Aculeatus Root Extract
AstringentAmmonium Glycyrrhizate
MaskingCitric Acid
Buffering
Centella Asiatica Leaf Extract
Skin Conditioning
Hydrolyzed Yeast Protein
Skin ConditioningCalendula Officinalis Flower Extract
Masking
Sodium Citrate
BufferingWater, Azelaic Acid, Betaine, Caprylic/Capric Triglyceride, Glycerin, Butylene Glycol, Pentylene Glycol, Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Lauryl Glucoside, Polyglyceryl-2 Dipolyhydroxystearate, Glycyrrhetinic Acid, Niacinamide, Ethylhexylglycerin, Panthenol, Sclerotium Gum, Chlorphenesin, Escin, O-Cymen-5-Ol, Polysorbate 60, Sorbitan Isostearate, Ruscus Aculeatus Root Extract, Ammonium Glycyrrhizate, Citric Acid, Centella Asiatica Leaf Extract, Hydrolyzed Yeast Protein, Calendula Officinalis Flower Extract, Sodium Citrate
Ivermectin 1%
Metronidazole 0.75%
Niacinamide 4%
Smoothing
Water
Skin ConditioningPropylene Glycol
Humectant
Glycerin
Humectant
Panthenol
Skin Conditioning
Cetyl Alcohol
Emollient
Glyceryl Stearate
Emollient
Isohexadecane
EmollientIsododecane
EmollientC13-15 Alkane
SolventDimethicone
Emollient
Propanediol
SolventPolyacrylate-13
Polyisobutene
Polysorbate 20
Emulsifying
Polyurethane-39
Phenoxyethanol 0.6%
Preservative
Tocopheryl Acetate
Antioxidant
Ceramide AP
Skin Conditioning
Ceramide NP
Skin Conditioning
Phytosphingosine
Skin Conditioning
Cholesterol
Emollient
Sodium Lauroyl Lactylate
EmulsifyingXanthan Gum
EmulsifyingCarbomer
Emulsion StabilisingSodium Hyaluronate
Humectant
Ivermectin 1%, Metronidazole 0.75%, Niacinamide 4%, Water, Propylene Glycol, Glycerin, Panthenol, Cetyl Alcohol, Glyceryl Stearate, Isohexadecane, Isododecane, C13-15 Alkane, Dimethicone, Propanediol, Polyacrylate-13, Polyisobutene, Polysorbate 20, Polyurethane-39, Phenoxyethanol 0.6%, Tocopheryl Acetate, Ceramide AP, Ceramide NP, Phytosphingosine, Cholesterol, Sodium Lauroyl Lactylate, Xanthan Gum, Carbomer, Sodium Hyaluronate
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinNiacinamide has emerged as an all-star ingredient due to its many benefits.
It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.
Other benefits include smoothing wrinkles and minimizing redness.
The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.
Learn more about NiacinamidePanthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolIngredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Isispharma Ruboril Metroruboril A.Z 28 ingredients
Dermatica Custom Formula (Ivermectin 1%, Metronidazole 0.75%, Niacinamide 4%) 28 ingredients
Reviews
Here's what our community thinks
Isispharma Ruboril Metroruboril A.Z 28 ingredients
Now been using this long term. I wanted to affordably introduce Azelaic acid into my routine for dark spots & redness. The ingredient list of this product stood out, 15% azelaic acid and not too many other ingredients.
Effects were quick and reduced redness on sensitive areas and on my cheek redness / rosacea. I’ve not had any negative effects even on my reactive skin so I’m happy to continue Show more
very light texture and my skin doesn't itch from it
