Ducray Keracnyl Serum Versus Uriage Dépiderm Anti-Brown Spot Intensive Night Cream
Updated on August 28, 2025
Overview
Cool Features
They both contain AHA and Vitamin E
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any harsh alcohols, common allergens, oils, parabens or sulfates
What's Inside
They both contain silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Ducray Keracnyl Serum 22 ingredients
Uriage Dépiderm Anti-Brown Spot Intensive Night Cream 35 ingredients
What's inside
What's inside
At a glance
Click on any of the items below to learn more
Ducray Keracnyl Serum 22 ingredients
Uriage Dépiderm Anti-Brown Spot Intensive Night Cream 35 ingredients
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningCaprylic/Capric Triglyceride
Masking
Azelaic Acid
Buffering
Dicaprylyl Ether
Emollient
Glycolic Acid
Buffering
Glycerin
Humectant
Nylon-12
Glyceryl Stearate
Emollient
Cetearyl Alcohol
Emollient
Sodium Hydroxide
BufferingDimethicone
Emollient
Acetic Acid
BufferingCeteareth-33
CleansingDisodium EDTA
Parfum
Masking
Glyceryl Laurate
Emollient
Myrtus Communis Leaf Extract
Perfuming
Niacinamide
Smoothing
Sclerotium Gum
Emulsion StabilisingSodium Chloride
Masking
Tocopherol
Antioxidant
Tocopheryl Acetate
Antioxidant
Water, Caprylic/Capric Triglyceride, Azelaic Acid, Dicaprylyl Ether, Glycolic Acid, Glycerin, Nylon-12, Glyceryl Stearate, Cetearyl Alcohol, Sodium Hydroxide, Dimethicone, Acetic Acid, Ceteareth-33, Disodium EDTA, Parfum, Glyceryl Laurate, Myrtus Communis Leaf Extract, Niacinamide, Sclerotium Gum, Sodium Chloride, Tocopherol, Tocopheryl Acetate
Water
Skin ConditioningEthylhexyl Palmitate
Emollient
Isocetyl Stearate
Emollient
Dicaprylyl Ether
Emollient
Glycerin
Humectant
Maltodextrin
Absorbent
Ascorbyl Tetraisopalmitate
Antioxidant
Butylene Glycol
Humectant
Dimethicone
Emollient
Glycolic Acid
Buffering
Steareth-2
EmulsifyingSteareth-21
CleansingLactic Acid
Buffering
Sodium Hydroxide
BufferingSucrose Dilaurate
Emollient
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Vp/Va Copolymer
Glycyrrhetinic Acid
Skin ConditioningJojoba Esters
Emollient
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingGlyceryl Behenate
Emollient
Glyceryl Stearate
Emollient
PEG-100
Humectant
PEG-100 Stearate
Helianthus Annuus Seed Wax
Skin Conditioning
Sodium Cocoyl Glutamate
CleansingXanthan Gum
EmulsifyingDimethiconol
Emollient
Pisum Sativum Extract
Skin ConditioningO-Cymen-5-Ol
Antimicrobial
Salicylic Acid
Masking
Tocopheryl Acetate
Antioxidant
Acacia Decurrens Flower Wax
Emollient
Polyglycerin-3
Humectant
Tocopherol
Antioxidant
Water, Ethylhexyl Palmitate, Isocetyl Stearate, Dicaprylyl Ether, Glycerin, Maltodextrin, Ascorbyl Tetraisopalmitate, Butylene Glycol, Dimethicone, Glycolic Acid, Steareth-2, Steareth-21, Lactic Acid, Sodium Hydroxide, Sucrose Dilaurate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Vp/Va Copolymer, Glycyrrhetinic Acid, Jojoba Esters, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Glyceryl Behenate, Glyceryl Stearate, PEG-100, PEG-100 Stearate, Helianthus Annuus Seed Wax, Sodium Cocoyl Glutamate, Xanthan Gum, Dimethiconol, Pisum Sativum Extract, O-Cymen-5-Ol, Salicylic Acid, Tocopheryl Acetate, Acacia Decurrens Flower Wax, Polyglycerin-3, Tocopherol
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Dicaprylyl Ether is created from caprylic acid. It is a texture-enhancer and emollient.
As an emollient, Dicaprylyl Ether is non-comedogenic. It helps soften and smooth the skin by creating a barrier on top. This barrier helps trap moisture in, helping to hydrate the skin.
Dicaprylyl Ether gives a non-greasy feel and better spreadability to products.
Learn more about Dicaprylyl EtherDimethicone is a type of synthetic silicone created from natural materials such as quartz.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinGlyceryl Stearate is a mix of glycerin and stearic acid.
It is used to stabilize the mixing of water and oil ingredients. By preventing these ingredients from separating, it can help elongate shelf life. It can also help thicken the product's texture.
As an emollient, it helps soften skin and supports barrier-replenishing ingredients.
In cosmetics, Glyceryl Stearate is often made from vegetable oils or synthetically produced.
This ingredient may not be fungal-acne safe
Fun fact: The human body also creates Glyceryl Stearate naturally.
Learn more about Glyceryl StearateGlycolic Acid is arguably the most famous alpha hydroxy acid (AHA) with tons of research backing its benefits.
It is found naturally in sugar cane but the form used in skincare is usually synthetic for purity and stability.
Glycolic acid removes the top layer of dead skin cells to allow newer and fresher ones to emerge.
AHAs work by breaking down the structural “glue” that holds old skin cells in place. When that buildup is gone, your skin can renew itself more efficiently.
Research also shows glycolic acid stimulates collagen production, helping to firm and thicken the skin over time. This is one of its biggest advantages over other AHAs.
Overall, glycolic acid helps with:
Fun fact: Glycolic acid boosts skin hydration by helping it produce molecules that increase hyaluronic acid naturally.
To work best, glycolic acid products should have a pH between 3-4 (that’s where exfoliation is most effective but still gentle on skin).
The pH and concentration of a product are key to its effectiveness:
It is normal to feel a slight stinging sensation when using glycolic acid. This usually fades as your skin adjusts.
Because glycolic acid has the smallest molecular size in the AHA family, it can penetrate deeper, which enhances its effectiveness but also makes it more likely to irritate sensitive skin.
If your skin is very sensitive or prone to rosacea, glycolic acid may be too strong; in that case, try milder options like lactic acid or a PHA instead.
Recent studies suggest glycolic acid might even help protect against UV damage. But don’t skip sunscreen! Freshly exfoliated skin is more sensitive to the sun.
Glycolic acid is a skincare superstar. It smooths, brightens, hydrates, and firms the skin. Unless you’re highly sensitive, it’s well worth adding to your routine.
Read more about some other popular AHA's here:
Learn more about Glycolic AcidSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideTocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterIngredient Ratings
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