Derma E Advanced Peptides And Collagen Moisturizer Versus Shiseido Benefiance Wrinkle Smoothing Cream
This anti-aging moisturizer is formulated around Palmitoyl Tripeptide-38 and Acetyl Hexapeptide-8 to soften the look of wrinkles and refine skin texture.
This anti-aging moisturizer is formulated around Niacinamide and Caffeine to soften the look of wrinkles and refine skin texture.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
HumectantMacadamia Ternifolia Seed Oil
EmollientCaprylic/Capric Triglyceride
MaskingStearic Acid
CleansingCetyl Alcohol
EmollientGlyceryl Stearate Citrate
EmollientDimethicone
EmollientHydroxypropyl Cyclodextrin
MaskingPalmitoyl Tripeptide-38
Skin ConditioningAcetyl Hexapeptide-8
HumectantPanthenol
Skin ConditioningPinus Pinaster Bark Extract
AntioxidantGlyceryl Stearate Se
EmulsifyingAcacia Seyal Gum Extract
HumectantTocopheryl Acetate
AntioxidantAscorbyl Palmitate
AntioxidantHamamelis Virginiana Bark/Leaf Extract
AstringentAesculus Hippocastanum Seed Extract
Skin ConditioningCamellia Sinensis Leaf Extract
AntimicrobialChamomilla Recutita Flower
Skin ConditioningSimmondsia Chinensis Seed Oil
EmollientAllantoin
Skin ConditioningXanthan Gum
EmulsifyingPotassium Sorbate
PreservativeSodium Hydroxide
BufferingPhenoxyethanol
PreservativeEthylhexylglycerin
Skin ConditioningParfum
MaskingWater, Glycerin, Macadamia Ternifolia Seed Oil, Caprylic/Capric Triglyceride, Stearic Acid, Cetyl Alcohol, Glyceryl Stearate Citrate, Dimethicone, Hydroxypropyl Cyclodextrin, Palmitoyl Tripeptide-38, Acetyl Hexapeptide-8, Panthenol, Pinus Pinaster Bark Extract, Glyceryl Stearate Se, Acacia Seyal Gum Extract, Tocopheryl Acetate, Ascorbyl Palmitate, Hamamelis Virginiana Bark/Leaf Extract, Aesculus Hippocastanum Seed Extract, Camellia Sinensis Leaf Extract, Chamomilla Recutita Flower, Simmondsia Chinensis Seed Oil, Allantoin, Xanthan Gum, Potassium Sorbate, Sodium Hydroxide, Phenoxyethanol, Ethylhexylglycerin, Parfum
Water
Skin ConditioningSd Alcohol 40-B
AstringentGlycerin
HumectantDipropylene Glycol
HumectantNiacinamide
SmoothingCyclohexasiloxane
EmollientCetyl Ethylhexanoate
EmollientHydrogenated Polydecene
EmollientPhytosteryl/Octyldodecyl Lauroyl Glutamate
Skin ConditioningDimethicone
EmollientPPG-3 Dipivalate
Skin ConditioningMyristyl Myristate
EmollientMethyl Methacrylate Crosspolymer
Hydrogenated Palm Oil
EmollientAmmonium Acryloyldimethyltaurate/Vp Copolymer
Behenyl Alcohol
EmollientPolysorbate 60
EmulsifyingPEG-30 Phytosterol
EmulsifyingPhenoxyethanol
PreservativeDimethicone/Vinyl Dimethicone Crosspolymer
Skin ConditioningBatyl Alcohol
EmollientAlcohol
AntimicrobialTocopheryl Acetate
AntioxidantErythritol
HumectantPEG/PPG-14/7 Dimethyl Ether
Skin ConditioningPEG/PPG-17/4 Dimethyl Ether
Skin ConditioningButylene Glycol
HumectantParfum
MaskingCarbomer
Emulsion StabilisingAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingPotassium Hydroxide
BufferingCaffeine
Skin ConditioningDisodium EDTA
ChelatingSodium Metaphosphate
BufferingTocopherol
AntioxidantSapindus Mukorossi Peel Extract
Skin ConditioningCI 77492
Cosmetic ColorantLinalool
PerfumingSodium Metabisulfite
AntioxidantLimonene
PerfumingCitronellol
PerfumingAngelica Keiskei Leaf/Stem Extract
Skin ConditioningGeraniol
PerfumingCamellia Sinensis Leaf Extract
AntimicrobialCitrus Junos Seed Extract
AntioxidantHdi/Trimethylol Hexyllactone Crosspolymer
Ziziphus Jujuba Fruit Extract
Skin ConditioningCI 77491
Cosmetic ColorantEucheuma Serra/Grateloupia Sparsa/Saccharina Angustata/Ulva Linza/Undaria Pinnatifida Extract
EmollientCurcuma Longa Rhizome Extract
Skin ConditioningSaccharina Angustata/Undaria Pinnatifida Extract
EmollientChlorella Vulgaris Extract
Skin ConditioningSilica
AbrasiveWater, Sd Alcohol 40-B, Glycerin, Dipropylene Glycol, Niacinamide, Cyclohexasiloxane, Cetyl Ethylhexanoate, Hydrogenated Polydecene, Phytosteryl/Octyldodecyl Lauroyl Glutamate, Dimethicone, PPG-3 Dipivalate, Myristyl Myristate, Methyl Methacrylate Crosspolymer, Hydrogenated Palm Oil, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Behenyl Alcohol, Polysorbate 60, PEG-30 Phytosterol, Phenoxyethanol, Dimethicone/Vinyl Dimethicone Crosspolymer, Batyl Alcohol, Alcohol, Tocopheryl Acetate, Erythritol, PEG/PPG-14/7 Dimethyl Ether, PEG/PPG-17/4 Dimethyl Ether, Butylene Glycol, Parfum, Carbomer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Potassium Hydroxide, Caffeine, Disodium EDTA, Sodium Metaphosphate, Tocopherol, Sapindus Mukorossi Peel Extract, CI 77492, Linalool, Sodium Metabisulfite, Limonene, Citronellol, Angelica Keiskei Leaf/Stem Extract, Geraniol, Camellia Sinensis Leaf Extract, Citrus Junos Seed Extract, Hdi/Trimethylol Hexyllactone Crosspolymer, Ziziphus Jujuba Fruit Extract, CI 77491, Eucheuma Serra/Grateloupia Sparsa/Saccharina Angustata/Ulva Linza/Undaria Pinnatifida Extract, Curcuma Longa Rhizome Extract, Saccharina Angustata/Undaria Pinnatifida Extract, Chlorella Vulgaris Extract, Silica
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Camellia Sinensis Leaf Extract (tea extract) is one of the most well-researched plant extracts in skincare with an impressive resume.
Black tea, green tea, and oolong tea are all harvested from the Camellia Sinensis plant.
Studies show green tea extract and its catechins (like epigallocatechin gallate (EGCG)) help your skin cells product energy more efficiently and reducing the number of free-radicals that can damage your skin from the inside.
In lab-grown skin models, this translated to younger, healthier, and stronger skin.
There's also good sun protection data; researchers saw less DNA damage and redness on human skin when green tea was applied before UVB exposure. And the more they applied, the better the protection.
Needless to say, this ingredient shouldn't replace your sunscreen. But it is a great supportive ingredient that you can already find in many sunscreens and antioxidant serums.
A 2009 study found a 2% green tea lotion was effective for mild-to-moderate acne thanks to its anti-inflammatory and mild antimicrobial activity.
The quality of the extract matters a lot here:
Good extracts contain 50-90% catechins while lower quality ones are mostly there for marketing. We recommend reaching out to the brand if you have questions about the quality or source of their ingredients.
Human Repeated Insult Patch Testing showed no irritation or sensitization at use concentrations (0.86% in leave-on products and up to 30% as leaf water).
Learn more about Camellia Sinensis Leaf ExtractDimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinParfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumPhenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolTocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Learn more about Tocopheryl AcetateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water