DefenAge 6-Week Perfection Neck Cream
A cruelty-free general moisturizer that contains aha, niacinamide, peptides and vitamin e.
Overview
What it is
General moisturizer with 40 ingredients that contains AHA, niacinamide, peptides and Vitamin E
Cool Features
It is cruelty-free and reef safe
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, parabens, silicones or sulfates
Fun facts
DefenAge is from United States.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
About this product
Ingredients List
Dive into the full list of ingredients.
Water
Skin ConditioningButyrospermum Parkii Butter
Skin ConditioningC13-15 Alkane
SolventCaprylic/Capric Triglyceride
MaskingPropanediol
SolventNiacinamide
SmoothingGlycerin
HumectantCetyl Alcohol
EmollientPhospholipids
Skin ConditioningSh-Oligopeptide-5 Sp
BleachingSh-Oligopeptide-107 Sp
Stearyl Alcohol
EmollientSimmondsia Chinensis Seed Oil
EmollientSqualane
EmollientLeontopodium Alpinum Callus Culture Extract
AntioxidantPalmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine
Skin ConditioningPalmitoyl Dipeptide-5 Diaminohydroxybutyrate
Skin ConditioningPalmitoyl Tripeptide-1
Skin ConditioningPalmitoyl Tetrapeptide-7
Skin ConditioningSea Whip Extract
Skin ConditioningUbiquinone
AntioxidantTocopheryl Acetate
AntioxidantPanthenol
Skin ConditioningSerum Albumin
HumectantAlanyl Glutamine
HumectantPalmitic Acid
EmollientSodium Stearoyl Glutamate
CleansingMethyl Glucose Sesquistearate
EmollientPolysorbate 20
EmulsifyingPolyacrylate Crosspolymer-6
Emulsion StabilisingXanthan Gum
EmulsifyingButylene Glycol
HumectantCarbomer
Emulsion StabilisingPhytic Acid
Sodium Phytate
Leuconostoc/Radish Root Ferment Filtrate
AntimicrobialCaprylhydroxamic Acid
1,2-Hexanediol
Skin ConditioningSorbic Acid
PreservativeSodium Chloride
MaskingWater, Butyrospermum Parkii Butter, C13-15 Alkane, Caprylic/Capric Triglyceride, Propanediol, Niacinamide, Glycerin, Cetyl Alcohol, Phospholipids, Sh-Oligopeptide-5 Sp, Sh-Oligopeptide-107 Sp, Stearyl Alcohol, Simmondsia Chinensis Seed Oil, Squalane, Leontopodium Alpinum Callus Culture Extract, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Dipeptide-5 Diaminohydroxybutyrate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Sea Whip Extract, Ubiquinone, Tocopheryl Acetate, Panthenol, Serum Albumin, Alanyl Glutamine, Palmitic Acid, Sodium Stearoyl Glutamate, Methyl Glucose Sesquistearate, Polysorbate 20, Polyacrylate Crosspolymer-6, Xanthan Gum, Butylene Glycol, Carbomer, Phytic Acid, Sodium Phytate, Leuconostoc/Radish Root Ferment Filtrate, Caprylhydroxamic Acid, 1,2-Hexanediol, Sorbic Acid, Sodium Chloride
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterButyrospermum Parkii Butter is a plant lipid from the fruit of the Shea Tree. It is an effective skin hydrator and emollient.
Emollients help soothe and soften your skin. It does this by creating a protective film on your skin. This barrier helps trap moisture and keeps your skin hydrated. Emollients may be effective at treating dry or itchy skin.
Shea butter is rich in antioxidants. Antioxidants help fight free-radicals, or molecules that may harm the body. It is also full of fatty acids including stearic acid and linoleic acid. These acids help replenish the skin and keep skin moisturized.
While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.
Shea butter may not be fungal acne safe. We recommend speaking with a professional if you have any concerns.
Learn more about Butyrospermum Parkii ButterC13-15 Alkane is a group of alkanes with 13 to 15 carbon atoms in the alkyl chain.
It is a solvent and texture enhancer. Solvents are used to keep ingredients together in a product. They can help dissolve ingredients to stable bases or help evenly distribute ingredients throughout the product.
This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.
Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.
Learn more about Caprylic/Capric TriglyceridePropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolNiacinamide has emerged as an all-star ingredient due to its many benefits.
It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.
Other benefits include smoothing wrinkles and minimizing redness.
The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.
Learn more about NiacinamideGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinCetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.
Its main roles are:
Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol. The FDA allows products labeled "alcohol-free" to have fatty alcohols.
Learn more about Cetyl AlcoholPhospholipids are naturally found in our skin as they are the main component of cell membranes. Phospholipids have humectant, emollient, antioxidant properties.
Phospholipids are complex lipids that contain glycerin, two fatty acids, and a phosphate group. Some foods that contain phospholipids include soybeans and milk. The phospholipids found in soy come from Lecithin. This ingredient can also be synthetically created.
Due to their hygroscopic nature, they act as both humectants and emollients. Humectants draw moisture from the air to your skin, while emollients help trap moisture in.
The phospholipids in our skin can be naturally depleted. Replenishing the phospholipids in our skin can help hydrate your skin.
Studies show phospholipids display antioxidant activity and may help with reducing the signs of aging.
This ingredient is non-occlusive.
Some types of phospholipids:
Learn more about PhospholipidsSh-Oligopeptide-5 Sp is a peptide.
Sh-Oligopeptide-107 Sp is a peptide.
Stearyl Alcohol is a type of fatty alcohol from stearic acid. It is a white, waxy compound used to emulsify ingredients.
Fatty Alcohols are most often used as an emollient or to thicken a product. Emollients help soothe and hydrate the skin by trapping moisture.
They are usually derived from natural fats and oils and therefore do not have the same drying or irritating effect as solvent alcohols. FDA allows products labeled "alcohol-free" to have fatty alcohols.
Learn more about Stearyl AlcoholThis oil comes from the seeds of the desert shrub called Jojoba. It is more commonly known as jojoba oil, a non-comedogenic oil.
Jojoba oil does not contain fragrance and has many fatty-acids, making it a great soothing ingredient.
It also contains Vitamin E, a great moisturizing ingredient. Vitamin E is also an antioxidant and protects your skin against oxidative damage.
This ingredient humectant properties, meaning it helps draw moisture from the air. This helps keep your skin hydrated.
While jojoba has antibacterial properties, it is only able to kill some strains of bacteria.
Studies also show it helps in wound healing. In fact, Indigenous cultures have used jojoba as a moisturizer and to help treat burns for centuries.
Fun fact: Jojoba oil similar to natural human skin sebum, so it has a great effect on dry skin. It is also promising with helping to regulate sebum production.
Due to its fatty acid content, Jojoba oil may not be fungal acne safe. We recommend speaking with a professional if you have any concerns.
Learn more about Simmondsia Chinensis Seed OilSqualane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.
Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.
Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.
Research shows that squalane is non-irritating (even at 100% concentration).
In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.
The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.
Is squalane vegan?
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Learn more about SqualaneLeontopodium Alpinum Callus Culture Extract is an antioxidant.
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine isn't fungal acne safe and is a peptide.
Palmitoyl Dipeptide-5 Diaminohydroxybutyrate isn't fungal acne safe and is a peptide.
Palmitoyl Tripeptide-1 is a 3-amino acid peptide. Peptides are building blocks for protein.
This ingredient is a signal peptide, meaning it tells our skin to create collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Palmitoyl Tripeptide-1 can help reduce wrinkles and make the skin look more youthful.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tripeptide-1Palmitoyl Tetrapeptide-7 is a peptide. Peptides are building blocks for protein.
This ingredient consists of four amino acids and palmitic acid. These amino acids are arginine, proline, glutamine, and glycine.
This ingredient has many benefits. These benefits include boosting collagen production, fighting inflammation, and reversing UV damage.
By preventing our bodies from producing interleukins, Palmitoyl Tetrapeptide-7 helps fight inflammation. An interleukin is a chemical that signals to the body to produce an inflammatory response. Interleukin production is accelerated by UV radiation.
Palmitoyl Tetrapeptide-7 tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tetrapeptide-7We don't have a description for Sea Whip Extract yet.
Ubiquinone (Coenzyme Q10) is a molecule already found in our bodies. It is a potent antioxidant and skin-soothing ingredient.
Aging and environmental exposure diminishes our skin's natural ubiquinone levels. This is much like our natural collagen and elastin.
The good news is: studies show applying this ingredient topically replenishes ubiquinone levels in our skin. This also comes with a ton of skin benefits. These benefits include:
Ubiquinone is considered a large molecule and cannot be absorbed into the lower layers of skin. This is why it is believed to be such an effective antioxidant: it protects our skin in the upper layers and prevents damage in the deeper layers.
When used in sunscreen, ubiquinone is shown to increase ingredient stability, increase SPF factor, and add to infrared protection.
Fun fact: ubiquinone is fat-soluble.
Learn more about UbiquinoneTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetatePanthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolWe don't have a description for Serum Albumin yet.
We don't have a description for Alanyl Glutamine yet.
Palmitic Acid is a fatty acid found in our skin. In cosmetics, it is usually derived from palm oil. It is a cleanser, emollient, and emulsifier.
As an emollient, it helps hydrate the skin. The emulsifying properties keep ingredients together in a product.
Palmitic Acid may not be fungal-acne safe.
Learn more about Palmitic AcidSodium Stearoyl Glutamate is an emulsifier and helps condition the skin. It is amino acid-based.
In higher amounts, it may act as a cleansing agent.
Methyl Glucose Sesquistearate isn't fungal acne safe.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.
Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.
The lauric acid used to create Polysorbate 20 is often derived from coconuts.
Polysorbate 20 may not be fungal acne safe.
Learn more about Polysorbate 20Polyacrylate Crosspolymer-6 is a texture enhancer and pH adjuster.
It is be used to thicken water-based products and create a gel-texture with a velvet feel.
One manufacturer claims this ingredient to have a pH range of 2-8 and to be biodegradable.
Learn more about Polyacrylate Crosspolymer-6Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
- It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
- It is a humectant, which means that it helps attract moisture into the skin.
- It helps improve product application.
- It has mild preservative properties.
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Carbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.
A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.
Phytic Acid is a gentle AHA and antioxidant. AHAs are chemical exfoliants that help remove dead skin cells. Phytic Acid has a slight and mild exfoliating effect.
The chemical makeup makes it classified as an AHA, much like lactic acid.
In some cases, it is a chelating agent. Chelating agents help prevent metals from binding to water, helping to stabilize the ingredients in a product.
An interesting fact about phytic acid is that it is considered an antinutrient. People do not have the enzyme needed to properly breakdown and digest phytic acid. When ingested, phytic acid binds to minerals and prevents them from being absorbed.
Read more about some other popular AHA's here:
Learn more about Phytic AcidSodium Phytate is the synthetic salt form of phytic acid. Phytic acid is an antioxidant and can be found in plant seeds.
Sodium Phytate is a chelating agent. Chelating agents help prevent metals from binding to water. This helps stabilize the ingredients and the product.
Leuconostoc/Radish Root Ferment Filtrate is a natural preservative. It comes from fermenting radish roots with a bacteria called leuconostoc.
Leuconostoc comes from lactic acid.
This ingredient has antimicrobial properties and helps prevent the growth of bacteria in a product.
Leuconostoc is used to make the traditional Korean side-dish, kimchi. It is also used to make sourdough bread (both incredibly yummy foods).
Learn more about Leuconostoc/Radish Root Ferment FiltrateCaprylhydroxamic Acid is a chelating agent.
Chelating agents help prevent metal ions from binding to other ingredients. This helps prevent unwanted reactions and effects from using the product.
Caprylhydroxamic Acid is often used with natural antimicrobial products as an alternative to preservatives.
Learn more about Caprylhydroxamic Acid1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Sorbic Acid is a preservative. It is the most commonly used food preservative in the world.
Sorbic Acid is a natural antibiotic and highly effective at preventing the growth of fungus. It is less effective against bacteria.
Potassium Sorbate, another commonly-used preservative, is the potassium salt of Sorbic Acid.
Sorbic Acid may worsen eczema. We recommend speaking with a professional if you have any concerns.
Potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
Learn more about Sorbic AcidChances are, you eat sodium chloride every day. Sodium Chloride is also known as table salt.
This ingredient has many purposes in skincare: thickener, emulsifier, and exfoliator.
You'll most likely find this ingredient in cleansers where it is used to create a gel-like texture. As an emulsifier, it also prevents ingredients from separating.
There is much debate on whether this ingredient is comedogenic. The short answer - comedogenic ratings don't tell the whole story. Learn more about comegodenic ratings here.
The concensus about this ingredient causing acne seems to be divided. Research is needed to understand if this ingredient does cause acne.
Scrubs may use salt as the primary exfoliating ingredient.
Learn more about Sodium ChlorideReviews
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Where it's from
DefenAge is a American brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated March 5, 2025 • Added by ajd1