BeautyAct Barrier Support Night Cream

Typical usage concentrations range from 1-5%.

Human testing shows it's non-irritating and non-sensitizing, and the EU Scientific Committee on Consumer Safety (SCCS) has cleared it at very high levels (79% in leave-on products).

The one thing worth knowing about its comedogenic score of 3-4 is to keep it in perspective: these ratings come from old rabbit-ear tests using 100% of pure ingredient and doesn't reflect how it behaves at low levels in a finished product.

Because it is an ester of palmitic acid (C16), it falls into the range that the Malassezia yeast can feed on and is considered not fungal acne safe.

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

It mostly stays on the surface of skin where it helps hydrate due to its large molecular size and low water solubility.

Due to it being derived from fatty acids, this ingredient may not be Malassezia or fungal acne safe.

Like other vegetable oils, Hydrogenated Rapeseed Oil helps keep your skin hydrated.

Rapeseed Oil and Canola Oil are derived from the same plant; rapeseed oil is industrial while canola oil is culinary.

Canola oil has an erucic acid level of 2% or less, while rapeseed oil is higher. Erucic acid is a monounsaturated omega-9 fatty acid.

When you wash your hair and skin with a surfactant-based cleanser, the surfactants grab onto everything. This includes your skin's natural lipids, or the fats that live in your skin barrier and sebum. Once you rinse these surfactants away, it leaves your skin feeling tight, dry, and clean (in a not-good way).

Re-fatting is essentially putting some of these lipids back. Glyceryl oleate deposits a thin layer of emollient lipids back on the skin or hair surface reduce some of the barrier damage.

Also, glyceryl oleate isn't a foreign molecule to your skin. It's chemically identical to something your skin already produces and manages naturally. This is why it tends to be well-tolerated with low risk of irritation.

Typical use levels range from 0.5-5%.

Glyceryl Oleate has a function of "perfuming" in the CosIng database. This just means that the ingredient has some scent character that can contribute to the product's overall smell.

The scent of this ingredient is described as "waxy".

As an ester of oleic acid, this ingredient may not be fungal acne safe. This is because oleic acid falls into the carbon-chain length that Malassezia can use as a substrate.

Typical concentrations range from 0.1-3%.

This ingredient is mild and non-irritating in nature.

Because it is derived from ricinoleic acid, this ingredient may not be fungal acne safe. Ricinoleic acid is an unsaturated fatty acid that the Malassezia yeast can metabolize.

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).

Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.

Shea butter also contains vitamins A and E which may contribute to antioxidant activity.

While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.

This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.

Emulsifiers help stabilize a product. They do this by preventing ingredients from separating, such as oils and water which do not mix naturally. Surfactants reduce surface tension, making it easier to rinse pollutants off skin.

Due to its relation to lauric acid, it may provide antimicrobial benefits.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Its fatty acid composition mimics that of the hydrolipidic film covering the surface of the epidermis.

This allows it to diffuse into the upper layers of the skin and integrate with the lipid matrix of the stratum corneum to improve barrier function without being greasy.

Studies have shown that it increases hydration of stratum corneum and the squalene component specifically contributes emollient properties and barrier-restoring effects.

A 2025 narrative review also highlighted olive-derived bioactives in:

Typical use levels for this ingredient run from 3-10%.

Fungal acne:
Whole olive oil contains significant triglycerides and free oleic acid that Malassezia can readily metabolize; the unsaponifiables fraction has had these fatty glycerides removed.

However, certain batches of this ingredient may contain sterol esters or free fatty acids depending on the refinement quality. These trace amounts of C12-24 fatty acids could be metabolized by Malassezia.

This ingredient may not be fungal acne safe but not everyone will react to it. It's best to patch test if you're unsure.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.

Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.

Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.

Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.

The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function.

Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing ceramides in skin and improving skin hydration.

Studies show products formulated with NMF ingredients help strengthen our skin's barrier. Having a healthy skin barrier reduces irritation and increases hydration. Our skin barrier is responsible for having plump and firm skin. It also helps protect our skin against infection, allergies, and inflammation.

Fun fact: Phytosphingosine is abundant in plants and fungi.

More ingredients that help boost collagen in skin:

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

This is a great ingredient for dry, compromised, or aging skin; our skin starts to produce less cholesterol with age.

Research shows cholesterol works best in combination with ceramides and fatty acids, the other two major components in your skin barrier.

Cholesterol is also a well-establish penetration enhancer and can help other actives absorb more effectively.

Cosmetic-grade cholesterol is usually derived from lanolin but plant and synthetic options also exist. We recommend reaching out to the brand if you have questions about their source of cholesterol.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

Because they mirror the lipids naturally found in the deeper layers of your skin, topical phospholipids help reinforce the lipid matrix, reduce transepidermal water loss, and leave skin feeling conditioned.

They're also used to form liposomes, or tiny self-assembling vesible used to stabilize actives like vitamin c or retinol. This helps these ingredients integrate into the upper layers of skin more easily.

Phospholipids are compatible with everything and the CIR Expert Panel has concluded them to be safe at current use levels.

Some types of phospholipids include:

The acidity of our skin is maintained by our glands and skin biome; normal pH level of skin is slightly acidic (~4.75-5.5).

Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.

EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base.

What makes Ceramide EOP special is its ultra-long fatty acid chain; this unique structure allows it to bridge the lipid layers in your skin barrier to prevent water loss (something no other ceramide can do).

Low levels of Ceramide EOP have been found in people with eczema and psoriasis.

Using it together with other ceramides, cholesterol, and linoleic acid have been shown to meaningfully improve hydration and reduce water loss.

In one clinical study, a regimen using Ceramide EOP, NP, and AP led to significant symptom improvements in patients with eczema, psoriasis, and dry skin in just 4 weeks.

You'll usually see concentrations between 0.1-0.5% in formulations. Overall, this is a well-tolerated and safe ingredient for cosmetic use.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Read more about some other popular AHA's here:

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.