Overview
Cool Features
They both contain peptides and Vitamin E
Suited For
They're both likely to be good for dry skin and brightening skin
Free From
They both do not contain any harsh alcohols or sulfates
What's Inside
They both contain silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
SkinMedica TNS® Advanced+ Serum 35 ingredients
ZO Skin Health Daily Power Defense 51 ingredients
At a glance
Click on any of the items below to learn more
SkinMedica TNS® Advanced+ Serum 35 ingredients
ZO Skin Health Daily Power Defense 51 ingredients
Notable Ingredients
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This product contains 2 ingredients that may have this attribute:
Benefits
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This product contains 2 ingredients that may have this attribute:
Notable Ingredients
This product contains 2 ingredients that may have this attribute:
This product contains 2 ingredients that may have this attribute:
This product contains 2 ingredients that may have this attribute:
Benefits
This product contains 2 ingredients that may have this attribute:
This product contains 2 ingredients that may have this attribute:
This product contains 1 ingredient that may have this attribute:
This product contains 2 ingredients that may have this attribute:
This product contains 2 ingredients that may have this attribute:
This product contains 2 ingredients that may have this attribute:
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Concerns
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This product contains 3 ingredients that may have this attribute:
Ingredients Side-by-side
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
This is a growth factor ingredient. Growth factors stimulate cell growth and healing.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
Chlorella Vulgaris Extract comes from the microalga, Chlorella vulgaris. It is hydrating and contains antioxidants. Studies also show Chlorella Vulgaris may help in rebuilding collagen and elastin.
Pyrus Malus Fruit Extract is extract from Apples. Apples are rich in Vitamin C, sugars, and antioxidants.
Hydroxyacetophenone is antioxidant and helps with skin conditioning.
Antioxidant Helps brighten skin
Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
Polyacrylate-13 is a type of acrylate polymer. Acrylate polymers are commonly used as adhesives in cosmetics.
Sclerotium Gum is a polysaccharide gum made by the fungus, Sclerotium rolfssii. It is similar to xanthan gum.
Lecithin is a term for a group of substances found in plants, animals, and humans. They are made up of mixture of fatty acids. These fatty acids usually are a mixture of phosphoric acid's choline ester connected to stearic, oleic, and palmitic acids. Most lecithins are created from plant ingredients scuh as sunflower.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Sodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
Aminomethyl Propanol is used to adjust the pH of products. It is also used as a base to create other organic compounds. Having a balanced pH is important for protecting your skin.
Disodium EDTA plays a role in making products more stable by aiding other preservatives.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent germ and microbial growth. By itself, it has a scent that is similar to that of a rose.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
Water, Pentylene Glycol, Human Neonatal Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Trifluoroacetyl Tripeptide-2, Dimer Tripeptide-43, Hydrolyzed Linseed Extract, Vitis Vinifera Flower Cell Extract, Pyrus Malus Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, Peg-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Dextran, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Cyclopentasiloxane is a silicone used to improve texture and trap moisture. An easier name for this is D5.
Cyclohexasiloxane is a type of silicone more commonly known as D6. It is an emollient and solvent.
Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
3 Concerns
Cetearyl alcohol is a mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is mainly used as an emulsifier. Emulsifiers help prevent the separation of oils and products. Due to its composition, it can also be used to thicken a product or help create foam.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
Steareth-20 is a waxy compound used to emulsify ingredients. It is created from stearyl alcohol.
Jojoba Esters is a wax created from Jojoba oil. It is an emollient and film-forming ingredient. In bead form, it is an exfoliator.
Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.
C14-22 Alcohols is made up of synthetic fatty alcohols. More specifically, these fatty alcohols contain 14 to 22 carbons in the alkyl chain.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent germ and microbial growth. By itself, it has a scent that is similar to that of a rose.
Cetearyl Glucoside is a surfactant and emulsifier. It can be produced from synthetic of natural sources of cetearyl alcohol and glucose.
Not safe for Fungal Acne
Safflower Oil/Palm Oil Aminopropanediol Esters is an oil and isn't fungal acne safe.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Not safe for Fungal Acne
Palmitoyl Oligopeptide is a form of peptide. It is created by blending peptides with palmitic acid. Peptides are building blocks for protein.
Not safe for Fungal Acne
Palmitoyl Tetrapeptide-7 is a peptide. Peptides are building blocks for protein.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
Disodium EDTA plays a role in making products more stable by aiding other preservatives.
Cellulose is the main component of plant cell walls. It is used as an emulsifier, absorbent, and texture enhancer.
Hexylene Glycol is a surfactant. Glycols are a class of alcohols. Hexylene Glycol is a surfactant and emulsifier.
Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
Beta-Glucan is a polysaccharide. It can be derived from the cell walls of seaweed, oats, yeast, and fungi.
1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.
Paraben 2 Concerns
Methylparaben is a preservative and is a paraben. It is used to prevent the growth of fungus, mold, and other harmful bacteria. Parabens are chemicals used as preservatives in both cosmetics and food.
Lecithin is a term for a group of substances found in plants, animals, and humans. They are made up of mixture of fatty acids. These fatty acids usually are a mixture of phosphoric acid's choline ester connected to stearic, oleic, and palmitic acids. Most lecithins are created from plant ingredients scuh as sunflower.
This ingredient is a semi-synthetic polymer created from cellulose. In case you need a refresher, cellulose is the main component of plant cell walls.
Sorbitol is a sugar alcohol. It is a hydrating and moisturizing agent created from the reduction process of glucose.
EDTA is the shortened name for ethylenediamine tetraacetic acid. It is a chelating agent and used to stabilize products.
May worsen Eczema
Benzoic Acid is used to preserve and adjust the pH of products.
Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
8 Benefits 3 Concerns
Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
7 Benefits 3 Concerns
Retinyl palmitate is a form of retinoid. Retinoids are the superstar class of anti-aging ingredients that include tretinoin and retinol.
Antioxidant Helps brighten skin
Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
Citrus Aurantium Dulcis Peel Oil is oil from the peel of an orange fruit.
Oil EU Allergen
Citrus Limon Peel Oil is created from the peels of the lemon. It is used to add a lemon-scent to products. Lemon peel oil also has antibacterial, antifungal, and antioxidant properties. However, it may also cause phototoxicity and sensitize skin.
Oil EU Allergen
Mentha Piperita Oil is the volatile oil obtained from the whole plant of the Peppermint plant.
Antioxidant 4 Benefits May cause irritation
Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Limonene is a fragrance that adds scent and taste to a formulation.
This pigment is called Ultramarine blue lazurite. It gives a saturated blue color, but can be used to create other colors as well.
Water, Cetearyl Isononanoate, Cyclopentasiloxane, Cyclohexasiloxane, Pentylene Glycol, Cetearyl Alcohol, Glycerin, Steareth-20, Jojoba Esters, Carbomer, C14-22 Alcohols, Phenoxyethanol, Cetearyl Glucoside, Safflower Oil/Palm Oil Aminopropanediol Esters, Polysorbate 20, Butylene Glycol, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7, Sodium Hydroxide, Caprylyl Glycol, C12-20 Alkyl Glucoside, Ethylhexylglycerin, Lactose, Disodium EDTA, Cellulose, Hexylene Glycol, Potassium Sorbate, Beta-Glucan, 1,2-Hexanediol, Methylparaben, Lecithin, Hydroxypropyl Methylcellulose, Sorbitol, EDTA, Benzoic Acid, Sodium Benzoate, Arabidopsis Thaliana Extract, Micrococcus Lysate, Retinol, Retinyl Palmitate, Tocopheryl Acetate, Citrus Aurantium Dulcis Peel Oil, Citrus Limon Peel Oil, Citrus Nobilis Peel Oil, Citrus Reticulata Peel Oil, Mentha Piperita Oil, Mimosa Tenuiflora Bark Extract, Tocopherol, Limonene, CI 77007, CI 60730
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. Talk about multi-purpose! If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterPentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can help thicken or emulsify a product. Emulsifiers help stabilize a product. It does this by preventing certain ingredients from separating.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateLecithin is a term for a group of substances found in plants, animals, and humans. They are made up of mixture of fatty acids. These fatty acids usually are a mixture of phosphoric acid's choline ester connected to stearic, oleic, and palmitic acids. Most lecithins are created from plant ingredients scuh as sunflower.
Lecithin is an emollient. Emollients help soften the skin and creates a barrier to keep moisture in.
As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can help ingredients be better absorbed by the skin. The phospholipids in Lecithin can produce liposomes. Liposomes help other ingredients get through the skin barrier.
Learn more about LecithinButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
- It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
- It is a humectant, which means that it helps attract moisture into the skin.
- It helps improve product application.
Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.
Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.
The lauric acid used to create Polysorbate 20 is often derived from coconuts.
Polysorbate 20 may not be fungal acne safe.
Learn more about Polysorbate 20Disodium EDTA plays a role in making products more stable by aiding other preservatives.
It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.
Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.
Learn more about Disodium EDTAPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent germ and microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Ingredient Ratings
Here's what our community thinks of the ingredients in these two products.
When to use
SkinMedica TNS® Advanced+ Serum 35 ingredients
ZO Skin Health Daily Power Defense 51 ingredients
Reviews
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