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SkinMedica TNS® Advanced+ Serum Ingredients Explained

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Published December 5, 2021 Added by bradley_gilbert

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Overview

What it is

Serum with 35 ingredients that contains peptides and Vitamin E

Cool Features

It is reef safe

Suited For

It has ingredients that are good for dry skin and brightening skin

Free From

It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens or sulfates

Fun facts

SkinMedica is from United States. This product is used in 68 routines created by our community.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

Serum with 35 ingredients that contains peptides and Vitamin E

Quick info

You should know

Notable Ingredients

Benefits

Ingredients 35

Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Pentylene Glycol Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

Human Neonatal Fibroblast Conditioned Media Skin Conditioning

This is a growth factor ingredient. Growth factors stimulate cell growth and healing.

Unknown Full details ->
Glycereth-7 Triacetate Emollient, Solvent

We don't have a description for Glycereth-7 Triacetate.

Unknown Full details ->
Shea Butter Ethyl Esters Emollient, Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Shea Butter Ethyl Esters isn't fungal acne safe.

Disliked Full details ->
Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Ethoxydiglycol Humectant, Solvent
0 / 0

Ethoxydiglycol is a synthetic solvent.

0 Com. / 0 Irr.
Lactococcus Ferment Lysate Skin Conditioning

We don't have a description for Lactococcus Ferment Lysate.

Whey Protein Skin Conditioning

We don't have a description for Whey Protein.

Disliked Full details ->
Chlorella Vulgaris Extract Skin Conditioning

Chlorella Vulgaris Extract comes from the microalga, Chlorella vulgaris. It is hydrating and contains antioxidants. Studies also show Chlorella Vulgaris may help in rebuilding collagen and elastin.

Saccharide Isomerate Humectant

Saccharide Isomerate comes from sugars found in corn. It is a skin hydrator.

Trifluoroacetyl Tripeptide-2 Skin Conditioning, Skin Protecting
Peptide Icon
PeptidePeptide Icon

Trifluoroacetyl Tripeptide-2 is a peptide.

Dimer Tripeptide-43
Peptide Icon
PeptidePeptide Icon

Dimer Tripeptide-43 is a peptide.

Unknown Full details ->
Hydrolyzed Linseed Extract Skin Conditioning

We don't have a description for Hydrolyzed Linseed Extract.

Unknown Full details ->
Vitis Vinifera Flower Cell Extract Masking, Skin Protecting

We don't have a description for Vitis Vinifera Flower Cell Extract.

Unknown Full details ->
Pyrus Malus Fruit Extract Skin Conditioning

Pyrus Malus Fruit Extract is extract from Apples. Apples are rich in Vitamin C, sugars, and antioxidants.

Hydroxyacetophenone Antioxidant
Antioxidant Icon
AntioxidantAntioxidant Icon

Hydroxyacetophenone is antioxidant and helps with skin conditioning.

Tocopheryl Acetate Antioxidant, Skin Conditioning
0 / 0 Vitamin E IconAntioxidant IconHelps brighten skin Icon
Vitamin EVitamin E Icon AntioxidantAntioxidant Icon Helps brighten skinHelps brighten skin Icon

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

0 Com. / 0 Irr.
Propanediol Solvent

Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.

Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Polyacrylate Crosspolymer-6 Emulsion Stabilising

Polyacrylate Crosspolymer-6 is a texture enhancer and pH adjuster.

Disliked Full details ->
Polyacrylate-13

Polyacrylate-13 is a type of acrylate polymer. Acrylate polymers are commonly used as adhesives in cosmetics.

Disliked Full details ->
Polyisobutene

Polyisobutene is a synthetic polymer made from isobutene.

Disliked Full details ->
Sclerotium Gum Emulsion Stabilising, Skin Conditioning

Sclerotium Gum is a polysaccharide gum made by the fungus, Sclerotium rolfssii. It is similar to xanthan gum.

Disliked Full details ->
Peg-12 Dimethicone Skin Conditioning
Silicon Icon
SiliconSilicon Icon

Peg-12 Dimethicone is a type of silicone.

Very Disliked Full details ->
Lecithin Emollient, Emulsifying, Skin Conditioning

Lecithin is a term for a group of substances found in plants, animals, and humans. They are made up of mixture of fatty acids. These fatty acids usually are a mixture of phosphoric acid's choline ester connected to stearic, oleic, and palmitic acids. Most lecithins are created from plant ingredients scuh as sunflower.

Disliked Full details ->
Pullulan

We don't have a description for Pullulan.

Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Sodium Citrate Buffering, Masking

Sodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.

Polysorbate 20 Emulsifying
0 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

0 Com. / 0 Irr.
Very Disliked Full details ->
Aminomethyl Propanol Buffering

Aminomethyl Propanol is used to adjust the pH of products. It is also used as a base to create other organic compounds. Having a balanced pH is important for protecting your skin.

Dextran

We don't have a description for Dextran.

Unknown Full details ->
Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Ingredient Ratings

Based on the number of likes and dislikes each ingredient has received.

12
5
12
6
liked
mixed
disliked
not rated

Ingredients Explained

This product contains 35 ingredients. Click on any ingredient to learn more about it
Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Skin Conditioning, Solvent
Mixed

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.

This property also makes Pentylene Glycol a great texture enhancer. It can help thicken or emulsify a product. Emulsifiers help stabilize a product. It does this by preventing certain ingredients from separating.

Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.

Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.

Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.

Learn more about Pentylene Glycol

This is a growth factor ingredient. Growth factors stimulate cell growth and healing.

Studies find they help with:

The term "conditioned media" refers to a mix of lab grown growth-factors. Just so you know - the US allows human-derived growth factors. However, human-derived growth factors are illegal in the EU and plant sources are used as an alternative.

According to Dr. Zoe Draelos, growth factors have some drawbacks:

However, many people have seen great results from using growth factor serums.

There is also controversy surrounding growth factors. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer.

Learn more about Human Neonatal Fibroblast Conditioned Media
Emollient, Solvent

We don't have a description for Glycereth-7 Triacetate.

Emollient, Skin Conditioning
Disliked

Shea Butter Ethyl Esters isn't fungal acne safe.

Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Solvent
Mixed

Ethoxydiglycol is a synthetic solvent.

Solvents are used to keep ingredients together in a product. They can help dissolve ingredients to stable bases or help evenly distribute ingredients throughout the product.

Ethoxydiglycol also helps deliver other key ingredients into the skin.

Learn more about Ethoxydiglycol
Skin Conditioning
Liked

We don't have a description for Lactococcus Ferment Lysate.

Skin Conditioning
Disliked

We don't have a description for Whey Protein.

Skin Conditioning
Liked

Chlorella Vulgaris Extract comes from the microalga, Chlorella vulgaris. It is hydrating and contains antioxidants. Studies also show Chlorella Vulgaris may help in rebuilding collagen and elastin.

Antioxidants help with the signs of aging by neutralizing free-radical molecules. Free-radical molecules, if left unchecked, may damage skin cells and DNA. On top of that, Chlorella Vulgaris helps condition and hydrate the skin.

Chlorella Vulgaris is made up of lipids, carbohydrates, and chlorophyll.

This ingredient is commonly used as food additive in Japan.

Learn more about Chlorella Vulgaris Extract
Humectant
Loved

Saccharide Isomerate comes from sugars found in corn. It is a skin hydrator.

The structure of this ingredient can be altered to be more similar to the carbohydrates found in our skin. This ability to mimic our skin gives it hydrating properties.

Specifically, saccharide Isomerate is a humectant. Humectants draw moisture from the air to our skin.

Research shows Saccharide Isomerate to be an effective moisturizer.

Learn more about Saccharide Isomerate
Skin Conditioning, Skin Protecting
Liked

Trifluoroacetyl Tripeptide-2 is a peptide.

Dimer Tripeptide-43 is a peptide.

Skin Conditioning

We don't have a description for Hydrolyzed Linseed Extract.

Masking, Skin Protecting

We don't have a description for Vitis Vinifera Flower Cell Extract.

Skin Conditioning
Liked

Pyrus Malus Fruit Extract is extract from Apples. Apples are rich in Vitamin C, sugars, and antioxidants.

The sugar in Apples are humectants and help hydrate the skin. On top of that, apples also contain some acids, such as malic acid. These acids may have a mild exfoliating effect.

Last, the phytochemicals found in apples are strong antioxidants. These antioxidants help with anti-aging as they protect your skin cells against oxidative damage.

Learn more about Pyrus Malus Fruit Extract
Antioxidant
Liked

Hydroxyacetophenone is antioxidant and helps with skin conditioning.

Antioxidants help fight off free-radical molecules. These unstable molecules may damage your skin cells. By helping stabilize free-radicals, antioxidants may help in anti-aging.

Hydroxyacetophenone boosts the efficiency of other preservatives.

Learn more about Hydroxyacetophenone
Antioxidant, Skin Conditioning
Liked

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate
Solvent
Liked

Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.

Propanediol is not likely to cause sensitivity and considered safe to use.

It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol
Emulsifying, Emulsion Stabilising, Gel Forming
Disliked

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum
Emulsion Stabilising
Disliked

Polyacrylate Crosspolymer-6 is a texture enhancer and pH adjuster.

It is be used to thicken water-based products and create a gel-texture with a velvet feel.

One manufacturer claims this ingredient to have a pH range of 2-8 and to be biodegradable.

Learn more about Polyacrylate Crosspolymer-6
Disliked

Polyacrylate-13 is a type of acrylate polymer. Acrylate polymers are commonly used as adhesives in cosmetics.

Polyacrylate-13 creates a film to protect the skin. It is also used to thicken and stabilize a product. It works by making water a gel-like consistency. This gel consistency helps suspend particles.

Polyacrylate-13 is a copolymer of acrylic acid, acrylamide, sodium acrylate, sodium acryloyldimethyltaurate monomers

Learn more about Polyacrylate-13
Disliked

Polyisobutene is a synthetic polymer made from isobutene.

It is a film-forming agent and helps bind ingredients together.

Polyisobutene is not absorbed by the skin.

Learn more about Polyisobutene
Emulsion Stabilising, Skin Conditioning
Disliked

Sclerotium Gum is a polysaccharide gum made by the fungus, Sclerotium rolfssii. It is similar to xanthan gum.

In cosmetics, Sclerotium Gum is used to thicken the texture and to help stabilize other ingredients.

As an emulsifier, Sclerotium Gum helps prevent ingredients from separating, such as water and oil.

Learn more about Sclerotium Gum
Skin Conditioning
Very Disliked

Peg-12 Dimethicone is a type of silicone.

Emollient, Emulsifying, Skin Conditioning
Disliked

Lecithin is a term for a group of substances found in plants, animals, and humans. They are made up of mixture of fatty acids. These fatty acids usually are a mixture of phosphoric acid's choline ester connected to stearic, oleic, and palmitic acids. Most lecithins are created from plant ingredients scuh as sunflower.

Lecithin is an emollient. Emollients help soften the skin and creates a barrier to keep moisture in.

As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can help ingredients be better absorbed by the skin. The phospholipids in Lecithin can produce liposomes. Liposomes help other ingredients get through the skin barrier.

Learn more about Lecithin
Liked

We don't have a description for Pullulan.

Humectant, Masking, Skin Conditioning
Mixed

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.

Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.

Buffering, Masking
Mixed

Sodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.

Sodium Citrate helps maintain the pH of a product. Normal pH level of skin is slightly acidic (~4.75-5.5). The acidity of our skin is maintained by our glands and skin biome. Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.

Sodium Citrate is a chelating agent. It neutralizes metal ions from water and prevents them from binding to other ingredients. This ensures the other ingredients will not be altered.

Learn more about Sodium Citrate
Emulsifying
Very Disliked

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.

Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.

The lauric acid used to create Polysorbate 20 is often derived from coconuts.

Polysorbate 20 may not be fungal acne safe.

Learn more about Polysorbate 20
Buffering
Liked

Aminomethyl Propanol is used to adjust the pH of products. It is also used as a base to create other organic compounds. Having a balanced pH is important for protecting your skin.

Aminomethyl propanol is safe to use in cosmetics up to 1%. It is soluble in water.

We don't have a description for Dextran.

Disliked

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
Preservative
Very Disliked

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Skin Conditioning
Mixed

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Reviews

5.0
from 1 rating
Srr1111's avatar

Srr1111

10 months ago · Dry Skin
Review

Keeps my skin youthful

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The data we've presented on this page has been verified by a member of the SkinSort Team.

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