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Updated on October 18, 2023

Overview

What they are

These products are both reef safe serums. They have a total of 8 ingredients in common

Cool Features

They both contain niacinamide

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores and dark spots

Free From

They both do not contain any harsh alcohols, common allergens, oils, parabens or sulfates

What's Inside

They both contain fragrances

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

SkinBetter Science Mystro Active Balance Serum
Dr. Idriss The Depuffer
Dr. Idriss The Depuffer
Serum
American Brand United States

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Concerns

Notable Ingredients

Benefits

Ingredients Side-by-side

found in both products
Mystro Active Balance Serum
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Copaifera Officinalis Resin Masking

We don't have a description for Copaifera Officinalis Resin.

Unknown Full details ->
Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Propanediol Solvent

Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.

Polyglyceryl-3 Distearate Emulsifying
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polyglyceryl-3 Distearate isn't fungal acne safe.

Very Disliked Full details ->
Isosorbide Dicaprylate Skin Conditioning

We don't have a description for Isosorbide Dicaprylate.

Unknown Full details ->
Cetearyl Glucoside Emulsifying

Cetearyl Glucoside is a surfactant and emulsifier. It can be produced from synthetic of natural sources of cetearyl alcohol and glucose.

Disliked Full details ->
Ethoxydiglycol Humectant, Solvent
0 / 0

Ethoxydiglycol is a synthetic solvent.

0 Com. / 0 Irr.
Diheptyl Succinate Emollient, Skin Conditioning

We don't have a description for Diheptyl Succinate.

Unknown Full details ->
Squalane Emollient, Skin Conditioning
1 / 0 Helps hydrate Dry Skin Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

1 Com. / 0 Irr.
Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Panax Notoginseng Root Extract Humectant

We don't have a description for Panax Notoginseng Root Extract.

Unknown Full details ->
Theobroma Cacao Leaf Cell Extract Masking, Skin Protecting

We don't have a description for Theobroma Cacao Leaf Cell Extract.

Unknown Full details ->
Chamomilla Recutita Flower Extract Masking, Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation Icon
2 Benefits

Chamomilla Recutita Flower Extract comes from the Chamomile flower.

Magnolia Officinalis Bark Extract Antimicrobial, Skin Conditioning

We don't have a description for Magnolia Officinalis Bark Extract.

Unknown Full details ->
Echinacea Purpurea Extract Moisturising, Skin Conditioning, Tonic

We don't have a description for Echinacea Purpurea Extract.

Unknown Full details ->
Sophora Japonica Bud Extract Skin Protecting, Soothing

We don't have a description for Sophora Japonica Bud Extract.

Unknown Full details ->
Humulus Lupulus Extract Antimicrobial, Masking, Skin Conditioning

We don't have a description for Humulus Lupulus Extract.

Unknown Full details ->
Curcuma Longa Root Extract Masking, Perfuming
Fragrance Icon
FragranceFragrance Icon

Curcuma Longa Root Extract is from the spice, turmeric. Besides being a healthy and delicious spice, turmeric also has plenty of skincare benefits. It has anti-inflammatory, antioxidant, and anti-microbial properties.

Hydrolyzed Sodium Hyaluronate Skin Conditioning

This ingredient is created by putting sodium hyaluronate through hydrolysis.

Haematococcus Pluvialis Extract Antioxidant
Antioxidant Icon
AntioxidantAntioxidant Icon

Haematococcus Pluvialis Extract is an antioxidant.

Astaxanthin Skin Conditioning

Astaxanthin is a carotene pigment and red pigment. It's what makes salmon a pink color.

Ergothioneine Antioxidant
Antioxidant Icon
AntioxidantAntioxidant Icon

Ergothioneine is an antioxidant.

Thioctic Acid Antioxidant
Antioxidant Icon
AntioxidantAntioxidant Icon

Thioctic Acid is an enzyme and antioxidant. A more common name for this is Alpha Lipoic Acid.

Sorbitan Olivate Emulsifying
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Sorbitan Olivate is created from the fatty acids in olive oil and sorbitol.

Very Disliked Full details ->
Tocopherol Antioxidant, Masking, Skin Conditioning
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation Icon
Vitamin EVitamin E Icon AntioxidantAntioxidant Icon 4 Benefits May cause irritationMay cause irritation Icon

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

0-3 Com. / 0-3 Irr.
Caprylic/Capric Triglyceride Masking, Skin Conditioning

Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

Capryloyl Glycerin/Sebacic Acid Copolymer Skin Conditioning, Skin Protecting

We don't have a description for Capryloyl Glycerin/Sebacic Acid Copolymer.

Unknown Full details ->
Sodium Stearoyl Glutamate Cleansing, Emulsifying, Skin Conditioning

Sodium Stearoyl Glutamate is an emulsifier and helps condition the skin. It is amino acid-based.

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate Antioxidant
Antioxidant Icon
AntioxidantAntioxidant Icon

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate (long name, huh?) is a synthetic antioxidant.

Glyceryl Stearate Citrate Emollient, Emulsifying, Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Glyceryl Stearate Citrate is a citric acid ester of glyceryl stearate.

Very Disliked Full details ->
Tribehenin Emollient, Skin Conditioning
0 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Tribehenin comes from glycerin and behenic acid.

0 Com. / 0 Irr.
Very Disliked Full details ->
Cetearyl Alcohol Emollient, Emulsifying, Emulsion Stabilising
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon
Fatty AlcoholFatty Alcohol Icon 3 Concerns

Cetearyl alcohol is a mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is mainly used as an emulsifier. Emulsifiers help prevent the separation of oils and products. Due to its composition, it can also be used to thicken a product or help create foam.

2 Com. / 1 Irr.
Very Disliked Full details ->
Acacia Senegal Gum Masking

We don't have a description for Acacia Senegal Gum.

Disliked Full details ->
Hydroxyethylcellulose Emulsion Stabilising, Stabilising

Hydroxyethylcellulose is used to improve the texture of products. It is created from a chemical reaction involving ethylene oxide and alkali-cellulose. Cellulose is a sugar found in plant cell walls and help give plants structure.

Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Phenethyl Alcohol Masking

Phenethyl Alcohol is a colorless and aromatic alohol. It is naturally occuring in essential oils.

Very Disliked Full details ->
Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
Citric Acid Buffering, Masking
AHA IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation IconMay worsen Rosacea Icon
AHAAHA Icon 4 Benefits 2 Concerns

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

Disliked Full details ->
Phytic Acid
AHA IconHelps brighten skin IconMay worsen Rosacea Icon
AHAAHA Icon Helps brighten skinHelps brighten skin Icon May worsen RosaceaMay worsen Rosacea Icon

Phytic Acid is a gentle AHA and antioxidant. The chemical makeup makes it classified as an AHA, such as lactic acid.

Sodium Hydroxide Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

The Depuffer
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Pentylene Glycol Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Propanediol Solvent

Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Emulsion Stabilising

This is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.

Disliked Full details ->
Squalane Emollient, Skin Conditioning
1 / 0 Helps hydrate Dry Skin Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

1 Com. / 0 Irr.
Arnica Montana Flower Extract Masking, Perfuming, Skin Conditioning
Fragrance Icon
FragranceFragrance Icon

Arnica Montana Flower is more commonly known as Wolf's Bane. While this flower has been used in traditional medicine, its skin benefits are in question.

Centella Asiatica Leaf Extract Skin Conditioning
Helps reduce Skin Redness Icon
Helps reduce Skin RednessHelps reduce Skin Redness Icon

Centella Asiatica Leaf Extract comes from the leaves of an herb plant native to Southeast Asia. Centella Asiatica is rich in antioxidants and amino acids. It can help reduce irritation and soothe the skin.

Fraxinus Excelsior Bark Extract Skin Conditioning

We don't have a description for Fraxinus Excelsior Bark Extract.

Unknown Full details ->
Agastache Mexicana Flower/Leaf/Stem Extract Skin Conditioning, Skin Protecting

Agastache Mexicana is a shrub from North America. All parts of this shrub contain antioxidants.

Unknown Full details ->
Avena Sativa Kernel Extract Abrasive, Antioxidant, Emollient
Exfoliant IconAntioxidant IconHelps hydrate Dry Skin Icon
ExfoliantExfoliant Icon AntioxidantAntioxidant Icon Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Avena Sativa Kernel Extract is is derived from colloidal oatmeal. Besides being a healthy breakfast, oats have many benefits in skincare too.

Camellia Sinensis Leaf Extract Antimicrobial, Antioxidant, Astringent
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconHelps fight Acne Icon
AntioxidantAntioxidant Icon 5 Benefits

Camellia Sinensis Leaf Extract is derived from the leaves of the tea plant. Black tea, green tea, and oolong tea are all harvested from this plant.

Hydroxyphenyl Propamidobenzoic Acid Skin Conditioning

We don't have a description for Hydroxyphenyl Propamidobenzoic Acid.

Unknown Full details ->
Maltodextrin Absorbent, Emulsion Stabilising, Skin Conditioning

Maltodextrin is a polysaccharide. It is derived from starch such as rice, corn, wheat, or potato starch.

Dimethicone Crosspolymer Emulsion Stabilising

Dimethicone Crosspolymer is a silicone created by modifying dimethicone with hydrocarbon side chains. Due to its large size, it does not penetrate skin. It is considered non-occlusive.

Very Disliked Full details ->
Silanetriol

We don't have a description for Silanetriol.

Unknown Full details ->
Sorbitan Isostearate Emulsifying
1-2 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Sorbitan Isostearate is an emulsifer and cleaning agent. It is created from isostearic acid and sorbitol.

1-2 Com. / 0 Irr.
Very Disliked Full details ->
Polysorbate 60 Emulsifying
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.

Very Disliked Full details ->
Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Hexylene Glycol Emulsifying, Skin Conditioning, Solvent
0-2 / 0-1

Hexylene Glycol is a surfactant. Glycols are a class of alcohols. Hexylene Glycol is a surfactant and emulsifier.

0-2 Com. / 0-1 Irr.
Disliked Full details ->
Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Masking, Skin Conditioning
Mixed

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.

Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.

Solvent
Liked

Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.

Propanediol is not likely to cause sensitivity and considered safe to use.

It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol
Emollient, Skin Conditioning
Loved

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.

Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.

Research shows that squalane is non-irritating (even at 100% concentration).

In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.

The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.

Is squalane vegan?

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Learn more about Squalane
Smoothing
Loved

Niacinamide has emerged as an all-star ingredient due to its many benefits.

It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Learn more about Niacinamide
Skin Conditioning
Mixed

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Preservative
Very Disliked

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Ingredient Ratings

Here's what our community thinks of the ingredients in these two products.

Mystro Active Balance Serum
14
8
11
10
liked
mixed
disliked
not rated
The Depuffer
11
3
6
4
liked
mixed
disliked
not rated

When to use

24 Routines
50% use in am
50% use in pm
100% use every day
9 Routines
78% use in am
22% use in pm
89% use every day

Reviews

Here's what our community thinks

SkinBetter Science Mystro Active Balance Serum 43 ingredients

3.0 /5
from 1 rating
Expensive (1)
AideeCantu's avatar

AideeCantu

2 months ago · Sensitive Skin
Review

Super expensive and I’m not sure I saw much of a difference. It helped a little bit with my redness but that’s all I noticed. It’s also hard to...

Super expensive and I’m not sure I saw much of a difference. It helped a little bit with my redness but that’s all I noticed. It’s also hard to spread around the face.

Dr. Idriss The Depuffer 24 ingredients

The Depuffer hasn't been rated yet.
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