SkinBetter Science Interufse Intensive Treatment Lines Versus DRMTLGY Needle-Less Serum
Updated on June 09, 2025
Overview
What they are
These products are both reef safe serums. They have a total of 11 ingredients in common
Cool Features
They both contain hyaluronic acid and peptides
Suited For
They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, reducing pores, scar healing and dark spots
Free From
They both do not contain any common allergens, fragrances, oils or parabens
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
SkinBetter Science Interufse Intensive Treatment Lines 41 ingredients
DRMTLGY Needle-Less Serum 29 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
SkinBetter Science Interufse Intensive Treatment Lines 41 ingredients
DRMTLGY Needle-Less Serum 29 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Ingredients Side-by-side
Water
Skin ConditioningC12-15 Alkyl Benzoate
AntimicrobialGlycerin
Humectant
PEG-16 Macadamia Glycerides
Emollient
Dimethicone
Emollient
Acetyl Glucosamine
Skin ConditioningAlcohol Denat.
Antimicrobial
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingSodium Citrate
BufferingTetrahexyldecyl Ascorbate
Antioxidant
Sodium Hyaluronate
Humectant
Glycine
Buffering
Hydroxyproline
Skin ConditioningProline
Skin ConditioningAcetyl Hexapeptide-8
Humectant
Hexapeptide-48 Hcl
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Skin Conditioning
Sodium Acetylated Hyaluronate
Humectant
Pisum Sativum Extract
Skin ConditioningGlycine Soja Seed Extract
Skin Conditioning
Glucosamine Hcl
Ophiopogon Japonicus Root Extract
Skin ConditioningBambusa Vulgaris Leaf/Stem Extract
HumectantHydrolyzed Lupine Protein
Skin ConditioningOleic Acid
Emollient
Sorbitan Isostearate
Emulsifying
C18-36 Acid Glycol Ester
EmollientPEG-7 Trimethylolpropane Coconut Ether
EmulsifyingSorbitan Laurate
Emulsifying
Hexylene Glycol
EmulsifyingPolyisobutene
C18-36 Acid Triglyceride
EmollientCarbomer
Emulsion StabilisingAcrylates Copolymer
Citric Acid
Buffering
Caprylyl Glycol
EmollientEthylhexylglycerin
Skin ConditioningPotassium Sorbate
Preservative
Phenoxyethanol
Preservative
Water, C12-15 Alkyl Benzoate, Glycerin, PEG-16 Macadamia Glycerides, Dimethicone, Acetyl Glucosamine, Alcohol Denat., Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium Citrate, Tetrahexyldecyl Ascorbate, Sodium Hyaluronate, Glycine, Hydroxyproline, Proline, Acetyl Hexapeptide-8, Hexapeptide-48 Hcl, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Sodium Acetylated Hyaluronate, Pisum Sativum Extract, Glycine Soja Seed Extract, Glucosamine Hcl, Ophiopogon Japonicus Root Extract, Bambusa Vulgaris Leaf/Stem Extract, Hydrolyzed Lupine Protein, Oleic Acid, Sorbitan Isostearate, C18-36 Acid Glycol Ester, PEG-7 Trimethylolpropane Coconut Ether, Sorbitan Laurate, Hexylene Glycol, Polyisobutene, C18-36 Acid Triglyceride, Carbomer, Acrylates Copolymer, Citric Acid, Caprylyl Glycol, Ethylhexylglycerin, Potassium Sorbate, Phenoxyethanol
Water
Skin ConditioningGlycerin
Humectant
Sodium Chondroitin Sulfate
Skin Conditioning
Sodium Hyaluronate
Humectant
Pisum Sativum Extract
Skin ConditioningBambusa Vulgaris Leaf/Stem Extract
HumectantPalmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Ceramide EOP
Skin Conditioning
Glucosamine Hcl
Glycosaminoglycans
EmollientCeramide NP
Skin Conditioning
Palmitoyl Tripeptide-5
Skin Conditioning
Ceramide AP
Skin Conditioning
Phytosphingosine
Skin Conditioning
Cholesterol
Emollient
Niacinamide
Smoothing
Sodium Lauroyl Lactylate
EmulsifyingMethylglucoside Phosphate
Skin ConditioningCopper Lysinate/Prolinate
Skin ConditioningPanthenol
Skin Conditioning
Tocopheryl Acetate
Antioxidant
Phenoxyethanol
Preservative
Polysorbate 20
Emulsifying
Ethylhexylglycerin
Skin ConditioningDisodium EDTA
Butylene Glycol
Humectant
Carbomer
Emulsion StabilisingXanthan Gum
EmulsifyingWater, Glycerin, Sodium Chondroitin Sulfate, Sodium Hyaluronate, Pisum Sativum Extract, Bambusa Vulgaris Leaf/Stem Extract, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP, Glucosamine Hcl, Glycosaminoglycans, Ceramide NP, Palmitoyl Tripeptide-5, Ceramide AP, Phytosphingosine, Cholesterol, Niacinamide, Sodium Lauroyl Lactylate, Methylglucoside Phosphate, Copper Lysinate/Prolinate, Panthenol, Tocopheryl Acetate, Phenoxyethanol, Polysorbate 20, Ethylhexylglycerin, Disodium EDTA, Butylene Glycol, Carbomer, Xanthan Gum
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Bambusa Vulgaris Leaf/Stem Extract comes from bamboo plant.
Bamboo extract has antioxidant properties. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.
A recent study found bamboo extract might interrupt the process of hyperpigmentation.
Learn more about Bambusa Vulgaris Leaf/Stem ExtractCarbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.
A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
We don't have a description for Glucosamine Hcl yet.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPalmitoyl Tetrapeptide-7 is a lab-made peptide with anti-inflammatory and skin-repairing benefits. It's made up of four amino acids (glycine, glutamine, proline, and arginine) and palmitic acid (which helps it penetrate skin more effectively).
This ingredient helps reduce inflammation by limiting the production of interleukin-6 (IL-6), a chemical that triggers inflammatory responses, particularly after UV exposure.
Less inflammation = slower collagen breakdown and a longer-lasting, youthful appearance.
Palmitoyl Tetrapeptide-7 also stimulates collagen production and supports a healthier skin barrier.
Over time, this can improve skin firmness, hydration, and reduce the appearance of fine lines. It’s commonly paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.
This ingredient has been shown to be effective and safe in cosmetic use and you'll typically find it in small amounts (less than 0.01%).
Due to its palmitic acid base, it may not be safe for Malassezia folliculitis.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tetrapeptide-7Palmitoyl Tripeptide-1 is also known as pal-GHK. It is made up of 3 amino acids and palmitic acid, a fatty acid that helps it absorb into skin more easily.
This peptide is as a signal peptide, meaning it tells the skin to produce more collagen. Collagen is the key protein that helps form the skin's structure and keep it plump, firm, and hydrated.
By boosting collagen production, this ingredient supports a stronger skin barrier and helps reduce the appearance of wrinkles.
You'll most likely see this ingredient paired with Palmitoyl Tetrapeptide-7 in the well-known Matrixyl 3000 complex. While results from in-house testing should be viewed cautiously, this peptide duo is among the most studied and widely used in modern skincare.
Due to its palmitic acid base, this ingredient may not be safe for Malassezia folliculitis.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tripeptide-1Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
We don't have a description for Pisum Sativum Extract yet.
Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterIngredient Ratings
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When to use
SkinBetter Science Interufse Intensive Treatment Lines 41 ingredients
DRMTLGY Needle-Less Serum 29 ingredients
Reviews
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