Explore Routine Login
Versus

SkinBetter Science Interufse Intensive Treatment Lines Versus DRMTLGY Needle-Less Serum

Serum
Serum
American Brand United States
American Brand United States

Updated on June 28, 2024

Overview

What they are

These products are both reef safe serums. They have a total of 11 ingredients in common

Cool Features

They both contain hyaluronic acid and peptides

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin and dark spots

Free From

They both do not contain any common allergens, fragrances, oils or parabens

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Concerns

Notable Ingredients

Benefits

Ingredients Side-by-side

found in both products
Interufse Intensive Treatment Lines
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

C12-15 Alkyl Benzoate Antimicrobial, Emollient, Skin Conditioning

C12-15 Alkyl Benzoate is made up of Benzoic Acid and long chain alcohols. It has a low molecular weight.

Disliked Full details ->
Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Peg-16 Macadamia Glycerides Emollient, Emulsifying
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Peg-16 Macadamia Glycerides isn't fungal acne safe.

Unknown Full details ->
Dimethicone Emollient, Skin Conditioning, Skin Protecting
1 / 0 Silicon Icon
SiliconSilicon Icon

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

1 Com. / 0 Irr.
Very Disliked Full details ->
Acetyl Glucosamine Skin Conditioning
Vitamin C Icon
Vitamin CVitamin C Icon

Acetyl Glucosamine is an antioxidant and humectant. It is a form of Vitamin C.

Alcohol Denat. Antimicrobial, Astringent, Masking
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon
AlcoholAlcohol Icon 5 Concerns

Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.

Very Disliked Full details ->
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Emulsion Stabilising

This is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.

Disliked Full details ->
Sodium Citrate Buffering, Masking

Sodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.

Ascorbyl Tetraisopalmitate Antioxidant, Emollient, Skin Conditioning
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Dark Spots IconNot safe for Fungal Acne Icon
Vitamin CVitamin C Icon AntioxidantAntioxidant Icon 4 Benefits Not safe for Fungal AcneNot safe for Fungal Acne Icon

Ascorbyl Tetraisopalmitate is a version of ascorbic acid, or pure Vitamin C.

Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Glycine Buffering, Skin Conditioning

Glycine is an amino acid that helps build proteins. It is already present in our skin as our bodies produce them naturally.

Hydroxyproline Skin Conditioning

We don't have a description for Hydroxyproline.

Unknown Full details ->
Proline Skin Conditioning

Proline is an amino-acid. It helps moisturize the skin and plays an important role in creating proteins.

Acetyl Hexapeptide-8 Humectant, Skin Conditioning
Peptide Icon
PeptidePeptide Icon

Acetyl Hexapeptide-8 is a peptide. A common name for this peptide is Argireline.

Hexapeptide-48 Hcl Skin Conditioning
Peptide Icon
PeptidePeptide Icon

Hexapeptide-48 Hcl is a peptide.

Unknown Full details ->
Palmitoyl Tripeptide-1 Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon
PeptidePeptide Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Palmitoyl Tripeptide-1 is a 3-amino acid peptide. Peptides are building blocks for protein.

Palmitoyl Tetrapeptide-7 Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon
PeptidePeptide Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Palmitoyl Tetrapeptide-7 is a peptide. Peptides are building blocks for protein.

Dipeptide Diaminobutyroyl Benzylamide Diacetate Skin Conditioning
Peptide Icon
PeptidePeptide Icon

Dipeptide Diaminobutyroyl Benzylamide Diacetate is a peptide.

Sodium Acetylated Hyaluronate Humectant
Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Acetylated Hyaluronate is a type of Hyaluronic Acid.

Pisum Sativum Extract Skin Conditioning, Skin Protecting

We don't have a description for Pisum Sativum Extract.

Glycine Soja Seed Extract Skin Conditioning

Glycine Soja Seed Extract comes from the seed of the wild soybean plant. Wild soybean extract contains fatty acids (linoleic, oleic, linolenic), vitamin E, and antioxidants.

Glucosamine Hcl

We don't have a description for Glucosamine Hcl.

Ophiopogon Japonicus Root Extract Skin Conditioning, Tonic

We don't have a description for Ophiopogon Japonicus Root Extract.

Bambusa Vulgaris Leaf/Stem Extract Humectant

Bambusa Vulgaris Leaf/Stem Extract comes from bamboo plant.

Hydrolyzed Lupine Protein Skin Conditioning

We don't have a description for Hydrolyzed Lupine Protein.

Unknown Full details ->
Oleic Acid Emollient, Emulsifying
May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon
3 Concerns

Oleic Acid is an Omega-9 fatty acid. It can be found in many plant oils such as avocado and marula oils.

Very Disliked Full details ->
Sorbitan Isostearate Emulsifying
1-2 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Sorbitan Isostearate is an emulsifer and cleaning agent. It is created from isostearic acid and sorbitol.

1-2 Com. / 0 Irr.
Very Disliked Full details ->
C18-36 Acid Glycol Ester Emollient, Emulsifying, Skin Conditioning

We don't have a description for C18-36 Acid Glycol Ester.

Unknown Full details ->
Peg-7 Trimethylolpropane Coconut Ether Emulsifying

This helper ingredient is a surfactant and emulsifier. It is created from coconut alcohol.

Unknown Full details ->
Sorbitan Laurate Emulsifying
1-2 / 1-2 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Sorbitan Laurate is created from lauric acid and derivatives from sorbitol. It is an emulsifier.

1-2 Com. / 1-2 Irr.
Very Disliked Full details ->
Hexylene Glycol Emulsifying, Skin Conditioning, Solvent
0-2 / 0-1

Hexylene Glycol is a surfactant. Glycols are a class of alcohols. Hexylene Glycol is a surfactant and emulsifier.

0-2 Com. / 0-1 Irr.
Disliked Full details ->
Polyisobutene

Polyisobutene is a synthetic polymer made from isobutene.

Disliked Full details ->
C18-36 Acid Triglyceride Emollient, Skin Conditioning

We don't have a description for C18-36 Acid Triglyceride.

Unknown Full details ->
Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Acrylates Copolymer

Acrylates Copolymer is used as a film-forming agent and texture enhancer.

Disliked Full details ->
Citric Acid Buffering, Masking
AHA IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation IconMay worsen Rosacea Icon
AHAAHA Icon 4 Benefits 2 Concerns

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

Disliked Full details ->
Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Potassium Sorbate Preservative
Preservative Icon
PreservativePreservative Icon

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

Disliked Full details ->
Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
Needle-Less Serum
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Sodium Chondroitin Sulfate Skin Conditioning
Sulfate Icon
SulfateSulfate Icon

Sodium Chondroitin Sulfate is a type of sulfate.

Unknown Full details ->
Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Pisum Sativum Extract Skin Conditioning, Skin Protecting

We don't have a description for Pisum Sativum Extract.

Bambusa Vulgaris Leaf/Stem Extract Humectant

Bambusa Vulgaris Leaf/Stem Extract comes from bamboo plant.

Palmitoyl Tripeptide-1 Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon
PeptidePeptide Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Palmitoyl Tripeptide-1 is a 3-amino acid peptide. Peptides are building blocks for protein.

Palmitoyl Tetrapeptide-7 Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon
PeptidePeptide Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Palmitoyl Tetrapeptide-7 is a peptide. Peptides are building blocks for protein.

Ceramide EOP Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon
CeramideCeramide Icon 4 Benefits

Ceramide EOP is a type of Ceramide.

Glucosamine Hcl

We don't have a description for Glucosamine Hcl.

Glycosaminoglycans Emollient, Skin Conditioning

We don't have a description for Glycosaminoglycans.

Unknown Full details ->
Ceramide NP Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon
CeramideCeramide Icon 4 Benefits

Ceramide NP is a type of ceramide.

Palmitoyl Tripeptide-5 Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon
PeptidePeptide Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Palmitoyl Tripeptide-5 isn't fungal acne safe and is a peptide.

Ceramide AP Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon
CeramideCeramide Icon 4 Benefits

Ceramide AP is a type of Ceramide.

Phytosphingosine Skin Conditioning

Phytosphingosine is a phospholipid naturally found in our skin. It helps moisturize, soothe, and protect skin.

Cholesterol Emollient, Emulsifying, Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness Icon
2 Benefits

Cholesterol is a class of organic molecules called lipids. It helps hydrate your skin and is essential to having a healthy skin barrier.

0 Com. / 0 Irr.
Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Sodium Lauroyl Lactylate Emulsifying

Sodium Lauroyl Lactylate is the lauric acid sodium salt of lactyl lactate.

Methylglucoside Phosphate Skin Conditioning

We don't have a description for Methylglucoside Phosphate.

Unknown Full details ->
Copper Lysinate/Prolinate Skin Conditioning

We don't have a description for Copper Lysinate/Prolinate.

Unknown Full details ->
Panthenol Skin Conditioning
0 / 0 Helps reduce irritation Icon
Helps reduce irritationHelps reduce irritation Icon

Panthenol is a common ingredient that helps hydrate and soothe the skin. It can be found naturally in our skin and hair.

0 Com. / 0 Irr.
Tocopheryl Acetate Antioxidant, Skin Conditioning
0 / 0 Vitamin E IconAntioxidant IconHelps brighten skin Icon
Vitamin EVitamin E Icon AntioxidantAntioxidant Icon Helps brighten skinHelps brighten skin Icon

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

0 Com. / 0 Irr.
Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
Polysorbate 20 Emulsifying
0 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

0 Com. / 0 Irr.
Very Disliked Full details ->
Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Skin Conditioning
Loved

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Skin Conditioning
Liked

Palmitoyl Tripeptide-1 is a 3-amino acid peptide. Peptides are building blocks for protein.

Palmitoyl Tripeptide-1 is a signal peptide. This means it tells our skin to create collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.

Palmitoyl Tripeptide-1 can help reduce wrinkles and make the skin look more youthful.

Read more about other common types of peptides here:

Learn more about Palmitoyl Tripeptide-1
Skin Conditioning
Liked

Palmitoyl Tetrapeptide-7 is a peptide. Peptides are building blocks for protein.

This ingredient consists of four amino acids and palmitic acid. These amino acids are arginine, proline, glutamine, and glycine.

This ingredient has many benefits. These benefits include boosting collagen production, fighting inflammation, and reversing UV damage.

By preventing our bodies from producing interleukins, Palmitoyl Tetrapeptide-7 helps fight inflammation. An interleukin is a chemical that signals to the body to produce an inflammatory response. Interleukin production is accelerated by UV radiation.

Palmitoyl Tetrapeptide-7 tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.

Read more about other common types of peptides here:

Learn more about Palmitoyl Tetrapeptide-7
Skin Conditioning, Skin Protecting
Liked

We don't have a description for Pisum Sativum Extract.

We don't have a description for Glucosamine Hcl.

Bambusa Vulgaris Leaf/Stem Extract comes from bamboo plant.

Bamboo extract has antioxidant properties. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.

A recent study found bamboo extract might interrupt the process of hyperpigmentation.

Learn more about Bambusa Vulgaris Leaf/Stem Extract
Emulsion Stabilising, Gel Forming
Disliked

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

Carbomer is commonly found in many types of cosmetics products. It is found to be safe in concentrations up to 15%. However, a high amount of carbomer can cause pilling or balling up of products. Most products contain 1% of less of carbomer.

Skin Conditioning
Mixed

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Preservative
Very Disliked

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Ingredient Ratings

Here's what our community thinks of the ingredients in these products.

Interufse Intensive Treatment Lines
16
4
14
7
liked
mixed
disliked
not rated
Needle-Less Serum
17
3
5
4
liked
mixed
disliked
not rated

When to use

3 Routines
33% use in am
67% use in pm
100% use every day
131 Routines
44% use in am
56% use in pm
98% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

SkinBetter Science Interufse Intensive Treatment Lines 41 ingredients

Interufse Intensive Treatment Lines hasn't been rated yet.
Rate it now

DRMTLGY Needle-Less Serum 29 ingredients

5.0 /5
from 2 ratings
Works Well (1)
MalloryZirpel_678's avatar

MalloryZirpel_678

9 months ago · Dry Skin
Review

Helps with fine lines

mandilou79's avatar

mandilou79

2 months ago · Dry Skin
Review

Love it