This anti-aging serum is formulated around Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-76 and Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1 to soften the look of wrinkles and refine skin texture.
This anti-aging serum is formulated around Niacinamide and Sh-Oligopeptide-1 to soften the look of wrinkles and strengthen the skin barrier.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
HumectantBis-PEG-18 Methyl Ether Dimethyl Silane
EmollientPropanediol
SolventLecithin
EmollientPEG-40 Hydrogenated Castor Oil
EmulsifyingMalus Domestica Fruit Cell Culture Extract
Skin ConditioningNicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-76
Skin ConditioningNicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-2
Skin ConditioningNicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1
Skin ConditioningNicotiana Benthamiana Sh-Polypeptide-15 Hexapeptide-40
Skin ConditioningAlcohol
AntimicrobialCaprooyl Tetrapeptide-3
Skin ProtectingCarbomer
Emulsion StabilisingCentella Asiatica Extract
CleansingDextran
Dipotassium Phosphate
BufferingDisodium EDTA
Tocopheryl Acetate
AntioxidantErgothioneine
AntioxidantEthylhexylglycerin
Skin ConditioningHydrochloric Acid
BufferingNicotiana Benthamiana Octapeptide-30 Sh-Oligopeptide-2
Skin ConditioningNicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-6
Skin ConditioningNicotiana Benthamiana Sh-Polypedtide-7
Skin ConditioningPalmitoyl Tripeptide-5
Skin ConditioningParfum
MaskingPhenoxyethanol
PreservativePolysorbate 20
EmulsifyingPotassium Phosphate
BufferingQuercetin
AntioxidantResveratrol Dimethyl Ether
AntioxidantSodium Chloride
MaskingSodium Cholate
Skin ConditioningTriethanolamine
BufferingTromethamine
BufferingXanthan Gum
EmulsifyingWater, Glycerin, Bis-PEG-18 Methyl Ether Dimethyl Silane, Propanediol, Lecithin, PEG-40 Hydrogenated Castor Oil, Malus Domestica Fruit Cell Culture Extract, Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-76, Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-2, Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1, Nicotiana Benthamiana Sh-Polypeptide-15 Hexapeptide-40, Alcohol, Caprooyl Tetrapeptide-3, Carbomer, Centella Asiatica Extract, Dextran, Dipotassium Phosphate, Disodium EDTA, Tocopheryl Acetate, Ergothioneine, Ethylhexylglycerin, Hydrochloric Acid, Nicotiana Benthamiana Octapeptide-30 Sh-Oligopeptide-2, Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-6, Nicotiana Benthamiana Sh-Polypedtide-7, Palmitoyl Tripeptide-5, Parfum, Phenoxyethanol, Polysorbate 20, Potassium Phosphate, Quercetin, Resveratrol Dimethyl Ether, Sodium Chloride, Sodium Cholate, Triethanolamine, Tromethamine, Xanthan Gum
Water
Skin ConditioningButylene Glycol
HumectantDipropylene Glycol
HumectantNiacinamide
SmoothingXylitol
Humectant1,2-Hexanediol
Skin ConditioningGlycereth-26
HumectantEctoin
Skin ConditioningCarbomer
Emulsion StabilisingC12-14 Alketh-12
EmulsifyingTromethamine
BufferingEthylhexylglycerin
Skin ConditioningTheobroma Cacao Seed Extract
AntioxidantDextrin
AbsorbentAdenosine
Skin ConditioningMethyl Diisopropyl Propionamide
MaskingDisodium EDTA
Cyanocobalamin
Skin ConditioningHydrogenated Phosphatidylcholine
EmulsifyingSh-Oligopeptide-1
Skin ConditioningGlycerin
HumectantRosa Canina Fruit Oil
EmollientNicotinamide Adenine Dinucleotide
Skin ConditioningXylitylglucoside
HumectantAnhydroxylitol
HumectantSorbitan Laurate
EmulsifyingLecithin
EmollientCaprylyl Glycol
EmollientPolyglyceryl-10 Laurate
Skin ConditioningHydroxyethylcellulose
Emulsion StabilisingAcetyl Glutamine
Skin ConditioningAcetyl Dipeptide-1 Cetyl Ester
Skin ConditioningHydrogenated Lecithin
EmulsifyingBacillus/Soybean Ferment Extract
Skin ConditioningVaccinium Vitis-Idaea Fruit Extract
AntioxidantVaccinium Myrtillus Fruit Extract
Skin ConditioningVaccinium Macrocarpon Fruit Extract
AstringentVaccinium Angustifolium Fruit Extract
Skin ProtectingUlmus Davidiana Root Extract
Skin ConditioningSambucus Nigra Fruit Extract
AstringentRubus Idaeus Fruit Extract
AstringentFragaria Vesca Fruit Extract
AstringentPueraria Lobata Root Extract
HumectantPinus Palustris Leaf Extract
TonicOenothera Biennis Flower Extract
AstringentEuterpe Oleracea Fruit Extract
Collagen Extract
Skin ConditioningPalmitoyl Tripeptide-5
Skin ConditioningHibiscus Sabdariffa Flower Extract
Skin ConditioningAcetyl Hexapeptide-1
Skin ConditioningAcetyl Octapeptide-3
HumectantSodium Hyaluronate
HumectantFolic Acid
Skin ConditioningFicus Carica Fruit Extract
HumectantGlutathione
Copper Tripeptide-1
Skin ConditioningOligopeptide-3
Skin ConditioningOligopeptide-2
Skin ConditioningOligopeptide-1
Skin ConditioningHexapeptide-11
Skin ConditioningWater, Butylene Glycol, Dipropylene Glycol, Niacinamide, Xylitol, 1,2-Hexanediol, Glycereth-26, Ectoin, Carbomer, C12-14 Alketh-12, Tromethamine, Ethylhexylglycerin, Theobroma Cacao Seed Extract, Dextrin, Adenosine, Methyl Diisopropyl Propionamide, Disodium EDTA, Cyanocobalamin, Hydrogenated Phosphatidylcholine, Sh-Oligopeptide-1, Glycerin, Rosa Canina Fruit Oil, Nicotinamide Adenine Dinucleotide, Xylitylglucoside, Anhydroxylitol, Sorbitan Laurate, Lecithin, Caprylyl Glycol, Polyglyceryl-10 Laurate, Hydroxyethylcellulose, Acetyl Glutamine, Acetyl Dipeptide-1 Cetyl Ester, Hydrogenated Lecithin, Bacillus/Soybean Ferment Extract, Vaccinium Vitis-Idaea Fruit Extract, Vaccinium Myrtillus Fruit Extract, Vaccinium Macrocarpon Fruit Extract, Vaccinium Angustifolium Fruit Extract, Ulmus Davidiana Root Extract, Sambucus Nigra Fruit Extract, Rubus Idaeus Fruit Extract, Fragaria Vesca Fruit Extract, Pueraria Lobata Root Extract, Pinus Palustris Leaf Extract, Oenothera Biennis Flower Extract, Euterpe Oleracea Fruit Extract, Collagen Extract, Palmitoyl Tripeptide-5, Hibiscus Sabdariffa Flower Extract, Acetyl Hexapeptide-1, Acetyl Octapeptide-3, Sodium Hyaluronate, Folic Acid, Ficus Carica Fruit Extract, Glutathione, Copper Tripeptide-1, Oligopeptide-3, Oligopeptide-2, Oligopeptide-1, Hexapeptide-11
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Learn more about CarbomerDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinLecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.
Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:
It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.
Learn more about LecithinPalmitoyl Tripeptide-5 is a synthetic signal lipopeptide. This just means it is a three amino acid chain bolted onto a palmitic acid tail so it can slip through the skin's lipid barrier.
This peptide has a "build more, lose less" approach.
It's designed to mimic the collagen-stimulating activity in your skin by copying a snippet of one of your skin's own matrix proteins. This nudges fibroblasts into making more collagen while inhibiting the enzyme that breaks down skin protein.
The manufacturer's in vivo study of 45 volunteers found 1% and 2.5% reduced the appearance of wrinkles by 7% and 12% respectively, after using it twice daily for 84 days.
This is in the expected range for peptides; they're slow and cumulative actives and not overnight fixers.
Typical use levels range from 1-3% and this ingredient gets along with pretty much everything.
On the fungal acne front:
Although palmitic acid sits in the chain length that Malassezia can feed on, this ingredient has it locked in an amine bond. This makes it hard for Malassezia to access as a source of food, and therefore fungal acne safe.
Tromethamine (aka THAM) is a synthetic amino acid that shows up in skincare as a helper ingredient.
It functions as a pH adjuster to help neutralize acidic ingredients and set a formula's pH to the right spot.
This matters a lot because a lot of actives (like vitamin C) needs a specific pH to work well and feel comfortable on skin.
Concentration use ranges from 0.1-1.0% depending on the formula.
Learn more about TromethamineWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water