Updated on December 06, 2023
Overview
What they are
These products are both reef safe serums. They have a total of 12 ingredients in common
Cool Features
They both contain niacinamide, peptides, retinoid and Vitamin E
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any harsh alcohols, common allergens, fragrances, parabens, silicones or sulfates
What's Inside
They both contain oils
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Qure All-in-one Face Serum 39 ingredients
SkinMedica Age Defense Retinol Complex 1.0 34 ingredients
At a glance
Click on any of the items below to learn more
Qure All-in-one Face Serum 39 ingredients
SkinMedica Age Defense Retinol Complex 1.0 34 ingredients
Notable Ingredients
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Ingredients Side-by-side
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Acetyl Hexapeptide-8 is a peptide. A common name for this peptide is Argireline.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
Maltodextrin is a polysaccharide. It is derived from starch such as rice, corn, wheat, or potato starch.
Sodium Cocoyl Glutamate is a gentle cleanser and surfactant. It is the sodium salt of the Cocoyl Glutamic Acid and comes from coconut oil. As a surfactant, it helps lift dirt and oil to be washed away.
Lecithin is a term for a group of substances found in plants, animals, and humans. They are made up of mixture of fatty acids. These fatty acids usually are a mixture of phosphoric acid's choline ester connected to stearic, oleic, and palmitic acids. Most lecithins are created from plant ingredients scuh as sunflower.
6 Benefits
Niacinamide has emerged as an all-star ingredient due to its many benefits.
1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.
Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
8 Benefits 3 Concerns
Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
BHT is a synthetic antioxidant. As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.
7 Benefits 3 Concerns
Retinyl palmitate is a form of retinoid. Retinoids are the superstar class of anti-aging ingredients that include tretinoin and retinol.
Not safe for Fungal Acne
Glycine Soja Oil comes from the soybean. Glycine Soja is native to eastern Asia.
Antioxidant 4 Benefits May cause irritation
Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
3 Benefits
Bakuchiol is a plant-derived antioxidant (it's vegan!). It is often called the replacement for retinol although it is not part of the same family.
6 Benefits 3 Concerns
Lactic Acid is an AHA that is derived from fermenting lactose, a carbohydrate from milk. It removes the top layer of old and dead skin cells and helps increase cell turnover.
Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.
5 Benefits
Camellia Sinensis Leaf Extract is derived from the leaves of the tea plant. Black tea, green tea, and oolong tea are all harvested from this plant.
Polyacrylate-13 is a type of acrylate polymer. Acrylate polymers are commonly used as adhesives in cosmetics.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
Antioxidant Helps brighten skin
Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
5 Benefits
You might know this ingredient as Ethyl Ascorbic Acid, a more stable version of ascorbic acid.
Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate (long name, huh?) is a synthetic antioxidant.
Helps with Anti-Aging
Ferulic Acid is a plant based antioxidant. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells. Ferulic Acid can help reduce the formation of fine lines and hyperpigmentation.
2 Benefits 2 Concerns
Mandelic Acid helps exfoliate skin. It also contains antioxidant properties.
Ginkgo Biloba Leaf Extract comes from the leaves of the Ginkgo tree. This tree is native to China and has been used in traditional Chinese medicine for thousands of years.
Terminalia Ferdinandiana Fruit Extract is from the Kakadu plum. The Kakadu plum is native to northern Australia. The Kakadu plum holds the record for having the highest amount of natural vitamin C.
Water, Acetyl Hexapeptide-8, Boswellia Serrata Resin Extract, Glycerin, Caprylic/Capric Triglyceride, Propylene Glycol, Sodium Hydroxide, Maltodextrin, Sucrose Dilaurate, Sodium Cocoyl Glutamate, Pisum Sativum Extract, Artemisia Umbelliformis Extract, Sodium Acrylates Copolymer, Lecithin, Niacinamide, 1,2-Hexanediol, Caprylyl Glycol, Tropolone, Retinol, BHT, Retinyl Palmitate, Glycine Soja Oil, Tocopherol, Bakuchiol, Glyceryl Oleate Citrate, Lactic Acid, Propanediol, Ganoderma Lucidum Extract, Camellia Sinensis Leaf Extract, Polyacrylate-13, Polyisobutene, Polysorbate 20, Tocopheryl Acetate, 3-O-Ethyl Ascorbic Acid, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Ferulic Acid, Mandelic Acid, Ginkgo Biloba Leaf Extract, Terminalia Ferdinandiana Fruit Extract
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Not safe for Fungal Acne
Glycine Soja Oil comes from the soybean. Glycine Soja is native to eastern Asia.
Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
6 Benefits
Niacinamide has emerged as an all-star ingredient due to its many benefits.
Polyacrylate-13 is a type of acrylate polymer. Acrylate polymers are commonly used as adhesives in cosmetics.
Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.
8 Benefits 3 Concerns
Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
Not safe for Fungal Acne
Palmitoyl Tripeptide-8 isn't fungal acne safe and is a peptide.
Antioxidant 4 Benefits May cause irritation
Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Bisabolol is pimarily used to add fragrance to a product. However, it is also famous for helping soothe skin.
Not safe for Fungal Acne
Squalene is naturally found in plants and animals, including our skin and sebum. It is a lipid our bodies naturally produce and makes up about 10-12% of the oil on our skin. Our skin produces squalene to keep itself naturally hydrated.
Antioxidant Helps brighten skin
Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
Oryza Sativa Bran Cera is wax from the outer layer of a rice kernel. It is a byproduct of milling rice, or the operation to produce a whole grain rice product.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Cetyl Palmitate is a wax-like substance.
Laureth-23 is created by reacting ethylene oxide with Lauryl Alcohol.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
Dicaprylyl Ether is created from caprylic acid. It is a texture-enhancer and emollient.
Lauryl Alcohol is a type of fatty alcohol. It is derived from palm kernel oil or coconut oil.
Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
Disodium EDTA plays a role in making products more stable by aiding other preservatives.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
Water, Cetyl Ethylhexanoate, Glycine Soja Oil, Caprylic/Capric Triglyceride, Niacinamide, Polyacrylate-13, Squalane, Retinol, Palmitoyl Tripeptide-8, Dunaliella Salina Extract, Magnolia Grandiflora Bark Extract, Tocopherol, Tocotrienols, Ceramide 3, Bisabolol, Phytosterols, Squalene, Tocopheryl Acetate, Oryza Sativa Bran Cera, Glycerin, Polysorbate 20, Butylene Glycol, Cetyl Palmitate, Laureth-23, Trideceth-6 Phosphate, Sodium Hydroxide, Dicaprylyl Ether, Lauryl Alcohol, Polyisobutene, Dextran, Potassium Sorbate, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinCaprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
Within a product, Caprylic Triglyceride can thicken the product and make spreadability easier by dissolving clumping compounds. An added benefit of Caprylic Triglyceride is its antioxidant properties.
Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid. Caprylic Triglyceride has not been found to be toxic for human use in concentrations under 50%.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.
Learn more about Caprylic/Capric TriglycerideSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideNiacinamide has emerged as an all-star ingredient due to its many benefits.
It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.
Other benefits include smoothing wrinkles and minimizing redness.
The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.
Learn more about NiacinamideRetinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
Why is retinol famous?
It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.
Retinol is proven to:
This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.
Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).
Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.
We recommend speaking with a medical professional about using this ingredient during pregnancy.
Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.
Read about Tretinoin
Learn more about RetinolGlycine Soja Oil comes from the soybean. Glycine Soja is native to eastern Asia.
Soybean oil is an emollient. It is rich in antioxidants and fatty acids including palmitic, stearic, oleic, and linoleic acids.
As an emollient, the fatty acids in soybean oil helps keep your skin soft and hydrated. It does so by creating a film on top that traps moisture in.
Soybean oil is also rich in vitamin E, a potent antioxidant. Vitamin E is also anti-inflammatory and provides a soothing effect.
Studies show soy may help fade hyperpigmentation from UVB. It does so by disrupting the melanin process from UVB induced skin inflammation.
This ingredient may not be malassezia folliculitis, or fungal-acne, safe.
Soybeans are rich in proteins and are part of the legume family. Foods made with soybeans include tofu, soymilk, edamame, miso, and soy sauce.
Learn more about Glycine Soja OilTocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolPolyacrylate-13 is a type of acrylate polymer. Acrylate polymers are commonly used as adhesives in cosmetics.
Polyacrylate-13 creates a film to protect the skin. It is also used to thicken and stabilize a product. It works by making water a gel-like consistency. This gel consistency helps suspend particles.
Polyacrylate-13 is a copolymer of acrylic acid, acrylamide, sodium acrylate, sodium acryloyldimethyltaurate monomers
Learn more about Polyacrylate-13Polyisobutene is a synthetic polymer made from isobutene.
It is a film-forming agent and helps bind ingredients together.
Polyisobutene is not absorbed by the skin.
Learn more about PolyisobutenePolysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.
Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.
The lauric acid used to create Polysorbate 20 is often derived from coconuts.
Polysorbate 20 may not be fungal acne safe.
Learn more about Polysorbate 20Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateIngredient Ratings
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Qure All-in-one Face Serum 39 ingredients
SkinMedica Age Defense Retinol Complex 1.0 34 ingredients
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