Numbuzin No.2 Rose PDRN Collagen Plumping Serum Versus VT Cosmetics PDRN Cica Exosome Ampoule
Updated on June 19, 2025
Overview
What they are
These products are both reef safe . They have a total of 7 ingredients in common
Cool Features
They both contain peptides and Vitamin E
Suited For
They're both likely to be good for anti aging, dry skin, sensitive skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any harsh alcohols, common allergens, parabens, silicones or sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Numbuzin No.2 Rose PDRN Collagen Plumping Serum 52 ingredients
VT Cosmetics PDRN Cica Exosome Ampoule 27 ingredients
What's inside
What's inside
At a glance
Click on any of the items below to learn more
Numbuzin No.2 Rose PDRN Collagen Plumping Serum 52 ingredients
VT Cosmetics PDRN Cica Exosome Ampoule 27 ingredients
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Collagen Water 62.94%
Humectant
Dipropylene Glycol
HumectantGlycereth-26
Humectant
Water
Skin ConditioningNiacinamide 5%
Smoothing
Glycerin
Humectant
Butylene Glycol
Humectant
Propanediol
Solvent
1,2-Hexanediol
Skin Conditioning
Trehalose
Humectant
PEG-240/Hdi Copolymer Bis-Decyltetradeceth-20 Ether
StabilisingDiethoxyethyl Succinate
SolventInositol
Humectant
Polyacrylate Crosspolymer-6
Emulsion StabilisingEthylhexylglycerin
Skin ConditioningOctyldodeceth-16
EmulsifyingSodium Dna 0.05%
Skin Conditioning
Rosa Damascena Flower Extract 0.05%
MaskingMethyl Diisopropyl Propionamide
MaskingAdenosine
Skin Conditioning
Polyglyceryl-10 Oleate
Skin Conditioning
Octyldodecanol
Emollient
Sodium Hyaluronate Crosspolymer
Humectant
Hydrogenated Lecithin
Emulsifying
Hydrolyzed Glycosaminoglycans
HumectantCyanocobalamin
Skin ConditioningPolysorbate 20
Emulsifying
Sodium Hyaluronate
Humectant
Disodium EDTA
Lecithin
Emollient
Potassium Laurate
EmulsifyingTocopherol
Antioxidant
Benzyl Glycol
SolventCaprylyl Glycol
Emollient
Resveratrol
Antioxidant
Hydrolyzed Hyaluronic Acid
Humectant
Hyaluronic Acid
Humectant
Polylactic Acid
Abrasive
Acetyl Hexapeptide-1
Skin Conditioning
Silica
Abrasive
Sodium Ascorbyl Phosphate
Antioxidant
Tripeptide-1
Skin Conditioning
Tripeptide-2
Skin Conditioning
Acetyl Hexapeptide-8
Humectant
Acetyl Octapeptide-3
Humectant
Palmitoyl Pentapeptide-4
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Raspberry Ketone
Masking
Sh-Oligopeptide-1
Skin Conditioning
Sh-Polypeptide-1
Skin Conditioning
Sh-Polypeptide-11
Sh-Polypeptide-22
Skin Conditioning
Collagen Water 62.94%, Dipropylene Glycol, Glycereth-26, Water, Niacinamide 5%, Glycerin, Butylene Glycol, Propanediol, 1,2-Hexanediol, Trehalose, PEG-240/Hdi Copolymer Bis-Decyltetradeceth-20 Ether, Diethoxyethyl Succinate, Inositol, Polyacrylate Crosspolymer-6, Ethylhexylglycerin, Octyldodeceth-16, Sodium Dna 0.05%, Rosa Damascena Flower Extract 0.05%, Methyl Diisopropyl Propionamide, Adenosine, Polyglyceryl-10 Oleate, Octyldodecanol, Sodium Hyaluronate Crosspolymer, Hydrogenated Lecithin, Hydrolyzed Glycosaminoglycans, Cyanocobalamin, Polysorbate 20, Sodium Hyaluronate, Disodium EDTA, Lecithin, Potassium Laurate, Tocopherol, Benzyl Glycol, Caprylyl Glycol, Resveratrol, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Polylactic Acid, Acetyl Hexapeptide-1, Silica, Sodium Ascorbyl Phosphate, Tripeptide-1, Tripeptide-2, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Raspberry Ketone, Sh-Oligopeptide-1, Sh-Polypeptide-1, Sh-Polypeptide-11, Sh-Polypeptide-22
Helianthus Annuus Seed Oil
Emollient
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingArginine
Masking
Tocopherol
Antioxidant
Adenosine
Skin Conditioning
Ceramide NP
Skin Conditioning
Adansonia Digitata Seed Oil
Emollient
Disodium EDTA
Hydrogenated Lecithin
Emulsifying
Squalane
Emollient
Allantoin
Skin Conditioning
Lactobacillus/Soymilk Ferment Filtrate
Skin ConditioningPanthenol
Skin Conditioning
Polyglucuronic Acid
Skin ConditioningCollagen Amino Acids
Moisturising
Ceramide As
Skin Conditioning
Ceramide Ns
Skin Conditioning
Butylene Glycol
Humectant
Pentylene Glycol
Skin ConditioningCeramide AP
Skin Conditioning
Ceramide EOP
Skin Conditioning
Haematococcus Pluvialis Extract
Antioxidant
Centella Asiatica Extract
Cleansing
Panax Ginseng Root Extract
Emollient
Copper Tripeptide-1
Skin Conditioning
Acetyl Hexapeptide-8
Humectant
Sodium Dna
Skin Conditioning
Helianthus Annuus Seed Oil, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Arginine, Tocopherol, Adenosine, Ceramide NP, Adansonia Digitata Seed Oil, Disodium EDTA, Hydrogenated Lecithin, Squalane, Allantoin, Lactobacillus/Soymilk Ferment Filtrate, Panthenol, Polyglucuronic Acid, Collagen Amino Acids, Ceramide As, Ceramide Ns, Butylene Glycol, Pentylene Glycol, Ceramide AP, Ceramide EOP, Haematococcus Pluvialis Extract, Centella Asiatica Extract, Panax Ginseng Root Extract, Copper Tripeptide-1, Acetyl Hexapeptide-8, Sodium Dna
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acetyl Hexapeptide-8, commonly known as Argireline, is a popular peptide in skincare. It’s often referred to as a “Botox-like” ingredient because it helps reduce muscle movement.
By relaxing these micro-movements, Argireline may help minimize the appearance of fine lines and wrinkles. That said, it’s not as powerful as Botox, and research on its long-term effectiveness is still limited.
Beyond smoothing, Argireline may also support collagen production. Collagen is the protein that helps keep your skin firm, bouncy, and well-hydrated by strengthening the skin barrier.
So while Argireline isn’t a miracle fix, it can be a helpful addition to a routine focused on both prevention and skin health.
Read more about other common types of peptides here:
Learn more about Acetyl Hexapeptide-8Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.
Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.
Studies have found adenosine may also help with wound healing.
In skincare products, Adenosine is usually derived from yeast.
Learn more about AdenosineButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolDisodium EDTA plays a role in making products more stable by aiding other preservatives.
It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.
Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.
Learn more about Disodium EDTAHydrogenated Lecithin is created from the hydrogenation of lecithin (a group of phospholipids). Hydrogenation is a chemical reaction between hydrogen and another element.
This ingredient is an emollient and emulsifier. As an emollient, it helps soften skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Sodium DNA is an emerging anti-aging ingredient.
It is created by taking deoxyribonucleic acid (DNA) and purifying it with sodium hydroxide.
The DNA is extracted from several different animal sources, including: calf thymus, the gonadic tissue of a male sturgeon, or herring / salmon sperm.
You have probably seen this ingredient in anti-aging skincare. But what is it?
DNA is composed of nucleotides, or chemical building blocks. Nucleotides include adenine (A), thymine (T), guanine (G), and cytosine (C). Talk about a flashback to biology! Nucleosides are formed from these nucleotides.
The science behind Sodium DNA is based on an ingredient called Polydeoxyribonucleotide or PDRN.
PDRN are DNA fragments mainly extracted from the sperm cells of trout or salmon. Meaning, PDRN can be derived from Sodium DNA.
PDRN consists of chains of nucleotides and nucleosides mentioned above. They can range anywhere from 80 - 2000 pairs.
Studies show PDRN has the following properties:
Most of the research on PDRN has been done using injectable forms. That’s important, because PDRN is a large molecule and doesn’t absorb well through the skin. So if you’re applying it topically, the effects are likely to be much milder.
Still, topical Sodium DNA is emerging as a trendy anti-aging ingredient. It’s generally well-tolerated and offers good biocompatibility with human skin, making it a low-risk addition to most routines.
Further studies are needed to truly confirm this ingredients anti-aging ability (Remember, retinol has decades of research!).
When using this ingredient, is is best to ask a brand about the source of their Sodium DNA. You'll want to find products where the Sodium DNA is sourced from fish. Some Sodium DNA is derived from calf / cow thymus.
Needless to say, this ingredient is not vegan.
Learn more about Sodium DnaTocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolIngredient Ratings
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