MediCube PDRN Pink Collagen Exosome Shot 2000 Versus BeautyBio R45 The Reversal 3-Phase Retinol Booster System
Updated on February 06, 2025
Overview
What they are
These products are both cruelty-free and reef safe facial treatments. They have a total of 10 ingredients in common
Cool Features
They both contain hyaluronic acid, peptides, retinoid and Vitamin E
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any common allergens, fragrances, parabens or sulfates
What's Inside
They both contain silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
MediCube PDRN Pink Collagen Exosome Shot 2000 50 ingredients
BeautyBio R45 The Reversal 3-Phase Retinol Booster System 33 ingredients
About this product
About this product
At a glance
Click on any of the items below to learn more
MediCube PDRN Pink Collagen Exosome Shot 2000 50 ingredients
BeautyBio R45 The Reversal 3-Phase Retinol Booster System 33 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningButylene Glycol
Humectant
Dipropylene Glycol
MaskingGlycerin
Humectant
Niacinamide
Smoothing
Sodium Polyacrylate
Absorbent1,2-Hexanediol
Skin ConditioningCaprylyl Glycol
EmollientCetearyl Olivate
Phenyl Trimethicone
Skin Conditioning
Sorbitan Olivate
Emulsifying
Hydrolyzed Sponge
Skin ConditioningGlyceryl Acrylate/Acrylic Acid Copolymer
HumectantEthylhexylglycerin
Skin ConditioningCalcium Aluminum Borosilicate
Adenosine
Skin Conditioning
Disodium EDTA
Pvm/Ma Copolymer
Emulsion StabilisingPanthenol
Skin Conditioning
Rosa Damascena Callus Extracellular Vesicles
Skin ConditioningCyanocobalamin
Skin ConditioningSodium Dna
Skin ConditioningMilk Exosomes
EmollientCollagen Extract
Skin Conditioning
Macadamia Ternifolia Seed Oil
Emollient
Caprylic/Capric Triglyceride
MaskingAlcohol Denat.
Antimicrobial
Hydrogenated Lecithin
EmulsifyingPolysorbate 20
Emulsifying
Retinol
Skin Conditioning
Chondrus Crispus Extract
Skin Conditioning
Cholesterol
Emollient
Sodium Hyaluronate
Humectant
PEG-5 Rapeseed Sterol
Cleansing
Polyglyceryl-10 Laurate
Skin Conditioning
Ceteth-3
EmulsifyingCeteth-5
EmulsifyingTocopheryl Acetate
Antioxidant
Hydrolyzed Elastin
EmollientPotassium Cetyl Phosphate
EmulsifyingHydroxypropyltrimonium Hyaluronate
Acetyl Tetrapeptide-5
Humectant
Palmitoyl Pentapeptide-4
Skin Conditioning
Sodium Acetylated Hyaluronate
Humectant
Hydrolyzed Hyaluronic Acid
Humectant
Palmitoyl Tripeptide-5
Skin Conditioning
Hyaluronic Acid
Humectant
Sodium Hyaluronate Crosspolymer
Humectant
Hydrolyzed Sodium Hyaluronate
Skin ConditioningPotassium Hyaluronate
Skin ConditioningWater, Butylene Glycol, Dipropylene Glycol, Glycerin, Niacinamide, Sodium Polyacrylate, 1,2-Hexanediol, Caprylyl Glycol, Cetearyl Olivate, Phenyl Trimethicone, Sorbitan Olivate, Hydrolyzed Sponge, Glyceryl Acrylate/Acrylic Acid Copolymer, Ethylhexylglycerin, Calcium Aluminum Borosilicate, Adenosine, Disodium EDTA, Pvm/Ma Copolymer, Panthenol, Rosa Damascena Callus Extracellular Vesicles, Cyanocobalamin, Sodium Dna, Milk Exosomes, Collagen Extract, Macadamia Ternifolia Seed Oil, Caprylic/Capric Triglyceride, Alcohol Denat., Hydrogenated Lecithin, Polysorbate 20, Retinol, Chondrus Crispus Extract, Cholesterol, Sodium Hyaluronate, PEG-5 Rapeseed Sterol, Polyglyceryl-10 Laurate, Ceteth-3, Ceteth-5, Tocopheryl Acetate, Hydrolyzed Elastin, Potassium Cetyl Phosphate, Hydroxypropyltrimonium Hyaluronate, Acetyl Tetrapeptide-5, Palmitoyl Pentapeptide-4, Sodium Acetylated Hyaluronate, Hydrolyzed Hyaluronic Acid, Palmitoyl Tripeptide-5, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate
Water
Skin ConditioningSafflower Acid
CleansingCocoglycerides
Emollient
Retinol
Skin Conditioning
Tocopheryl Acetate
Antioxidant
Safflower Glyceride
EmollientGlyceryl Diretinoate
Skin Conditioning
Lysolecithin
EmulsifyingSodium Hyaluronate
Humectant
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingCaprylyl Glycol
EmollientAcetyl Carboxymethyl Cocoyl Glycine
Polyglyceryl-10 Laurate
Skin Conditioning
Phenoxyethanol
Preservative
Citric Acid
Buffering
Glycerin
Humectant
Dipropylene Glycol
MaskingPropylene Glycol
Humectant
Cyclopentasiloxane
Emollient
PEG-12 Dimethicone Crosspolymer
EmulsifyingDimethicone Crosspolymer
Emulsion StabilisingDimethicone/Vinyl Dimethicone Crosspolymer
Skin ConditioningDimethiconol
Emollient
Butylene Glycol
Humectant
Pentylene Glycol
Skin ConditioningHydroxyphenyl Propamidobenzoic Acid
Skin ConditioningMyristoyl Pentapeptide-17
Skin Conditioning
Sodium Polyacrylate
AbsorbentTrideceth-6
EmulsifyingPolysorbate 60
Emulsifying
PEG/PPG-18/18 Dimethicone
Emulsifying
Disodium EDTA-Copper
AstringentDimethicone
Emollient
Water, Safflower Acid, Cocoglycerides, Retinol, Tocopheryl Acetate, Safflower Glyceride, Glyceryl Diretinoate, Lysolecithin, Sodium Hyaluronate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylyl Glycol, Acetyl Carboxymethyl Cocoyl Glycine, Polyglyceryl-10 Laurate, Phenoxyethanol, Citric Acid, Glycerin, Dipropylene Glycol, Propylene Glycol, Cyclopentasiloxane, PEG-12 Dimethicone Crosspolymer, Dimethicone Crosspolymer, Dimethicone/Vinyl Dimethicone Crosspolymer, Dimethiconol, Butylene Glycol, Pentylene Glycol, Hydroxyphenyl Propamidobenzoic Acid, Myristoyl Pentapeptide-17, Sodium Polyacrylate, Trideceth-6, Polysorbate 60, PEG/PPG-18/18 Dimethicone, Disodium EDTA-Copper, Dimethicone
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
- It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
- It is a humectant, which means that it helps attract moisture into the skin.
- It helps improve product application.
- It has mild preservative properties.
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Dipropylene Glycol is a synthetically created stabilizer and solvent. It is a part of the glycol class in the alcohol family.
Dipropylene Glycol helps dissolve and evenly distribute ingredients. It also helps decrease viscosity and thin out texture.
As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.
Studies show Dipropylene Glycol is considered safe to use in skincare.
Learn more about Dipropylene GlycolGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinSodium Polyacrylate is the sodium salt of polyacrylic acid. It is used as an absorber, emollient, and stabilizer.
This ingredient is a super-absorbent polymer - meaning it can absorb 100 to 1000 times its mass in water. As an emollient, Sodium Polyacrylate helps soften and soothe skin. Emollients work by creating a barrier to trap moisture in. This helps keep your skin hydrated.
Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.
Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.
This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.
Learn more about Caprylyl GlycolRetinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
Why is retinol famous?
It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.
Retinol is proven to:
This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.
Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).
Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.
We recommend speaking with a medical professional about using this ingredient during pregnancy.
Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.
Read about Tretinoin
Learn more about RetinolSodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronatePolyglyceryl-10 Laurate is an ester of lauric acid and Polyglycerin-10.
Polyglyceryl-10 Laurate is a cleansing agent and emulsifier. It helps gather dirt, oil, and other pollutants to be rinsed away. As an emulsifier, it helps prevent ingredients from separating, such as oil and water.
Polyglyceryl-10 Laurate may not be fungal acne safe.
Learn more about Polyglyceryl-10 LaurateTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateIngredient Ratings
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