ma:nyo Bifida Biome Complex Ampoule Versus Numbuzin No.3 Skin Softening Serum
Updated on July 18, 2023
Overview
What they are
These products are both cruelty-free and reef safe . They have a total of 12 ingredients in common
Cool Features
They both contain hyaluronic acid and niacinamide
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing and dark spots
Free From
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
ma:nyo Bifida Biome Complex Ampoule 45 ingredients
Numbuzin No.3 Skin Softening Serum 28 ingredients
At a glance
Click on any of the items below to learn more
ma:nyo Bifida Biome Complex Ampoule 45 ingredients
Numbuzin No.3 Skin Softening Serum 28 ingredients
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Ingredients Side-by-side
Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Saccharomyces Ferment Filtrate is created from fermenting Saccharomyces, a yeast also known as baker's yeast or brewer's yeast.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
6 Benefits
Niacinamide has emerged as an all-star ingredient due to its many benefits.
1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.
4 Benefits May cause irritation
Hyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.
Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Sodium Hyaluronate Crosspolymer is a type of hyaluronic acid. In fact, it is modified version of hyaluronic acid.
Hydrolyzed Hyaluronic Acid is a form of hyaluronic acid. It is created by the hydrolysis of hyaluronic acid with a high molecular weight. Once created, Hydrolyzed Hyaluronic Acid has a low molecular weight.
We don't have a description for Cutibacterium Granulosum Ferment Extract Filtrate.
Asiaticoside comes from the super popular skin-soothing ingredient, Centella asiatica. It is one of four active compounds found in the extract of Centella Asiatica.
Asiatic Acid is a major component of Centella Asiatica Extract. It has wound-healing, anti-inflammatory, and antioxidant properties.
Madecassic Acid is a major component of Centella Asiatica Extract. It has anti-inflammatory and antioxidant properties.
Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.
Hydrogenated Lecithin is created from the hydrogenation of lecithin. Hydrogenation is a chemical reaction between molecule hydrogen and another element.
Helps with Anti-Aging
Copper Tripeptide-1 is a peptide naturally found in body fluids. Peptides are building blocks for protein.
Tromethamine is an aliphatic compound. An aliphatic compound is an organic compound with open-chained carbon atoms. It is synthetically created. Tromethamine is used to balance pH and improve texture.
Acetyl Hexapeptide-8 is a peptide. A common name for this peptide is Argireline.
Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
Dextrin is used to thicken a product and helps bind ingredients together. It is created from starch and glycogen.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Caffeine is most associated with coffee, tea, and cacao. In skincare, it helps with calming inflammation and anti-aging.
Sodium Phytate is the synthetic salt form of phytic acid. Phytic acid is an antioxidant and can be found in plant seeds.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
EGCG is most famous for being found in green tea. It is a type of catechin, a potent antioxidant.
Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.
Polyglyceryl-10 Laurate is an ester of lauric acid and Polyglycerin-10.
Theobroma Cacao Seed Extract comes from the Theobroma cacoa, or Cacao tree. Cacao trees are native to tropical landscapes.
Bifida Ferment Lysate 72%, Butylene Glycol, Bifida Ferment Filtrate, Lactobacillus Ferment Lysate, Lactococcus Ferment Lysate, Saccharomyces Ferment Filtrate, Glycerin, Niacinamide, 1,2-Hexanediol, Lactobacillus/Pumpkin Fruit Ferment Filtrate, Aureobasidium Pullulans Ferment, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Sodium Acetylated Hyaluronate, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Leontopodium Alpinum Callus Culture Extract, Cutibacterium Granulosum Ferment Extract Filtrate, Asiaticoside, Asiatic Acid, Madecassic Acid, Pentylene Glycol, Squalane, Hydrogenated Lecithin, Copper Tripeptide-1, Tromethamine, Acetyl Hexapeptide-8, Propanediol, Ethylhexylglycerin, Dextrin, Water, Caffeine, Benzyl Glycol, Sodium Phytate, Hydrolyzed Algin, Xanthan Gum, Epigallocatechin Gallate, Carbomer, Physalis Alkekengi Calyx Extract, Hydrolyzed Glycosaminoglycans, Polyglyceryl-10 Laurate, Theobroma Cacao Seed Extract
Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.
Not safe for Fungal Acne
Galactomyces Ferment Filtrate (GFF) is a yeast traditionally used to make the Japanese alcoholic beverage, sake.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Methyl Gluceth-20 is a humectant. Humectants help draw moisture from the air to your skin.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
6 Benefits
Niacinamide has emerged as an all-star ingredient due to its many benefits.
1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.
Alteromonas Ferment Extract is derived from a bacteria from in deep sea water.
Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It can be found naturally in our skin and hair.
Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.
Glycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
Polyglyceryl-3 Distearate isn't fungal acne safe.
Glyceryl Stearate Se is a self-emulsifying (SE) form of glyceryl stearate. Self-emusifying means this ingredient automatically blends with water. It is an emulsifier, emollient, and cleansing agent.
Glyceryl Stearate Citrate is a citric acid ester of glyceryl stearate.
Polyglyceryl-3 Methylglucose Distearate is created from the diester of stearic acid and the condensation product of methylglucose and Polyglycerin-3.
Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.
Tromethamine is an aliphatic compound. An aliphatic compound is an organic compound with open-chained carbon atoms. It is synthetically created. Tromethamine is used to balance pH and improve texture.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
Disodium EDTA plays a role in making products more stable by aiding other preservatives.
Bifida Ferment Lysate 42%, Galactomyces Ferment Filtrate 21%, Butylene Glycol, Methyl Gluceth-20, Water, Niacinamide, Peg-90, 1,2-Hexanediol, Glycerin, Squalane, Alteromonas Ferment Extract, Silk Extract, Goat Milk Extract, Sodium Hyaluronate, Panthenol, Adenosine, Glycereth-26, Xanthan Gum, Polyglyceryl-3 Distearate, Glyceryl Stearate Se, Glyceryl Stearate Citrate, Polyglyceryl-3 Methylglucose Distearate, Carbomer, Tromethamine, Ethylhexylglycerin, Caprylyl Glycol, Tropolone, Disodium EDTA
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.
Having a healthy microbiome helps protect our skin against infection. It also helps our skin stay hydrated and healthy.
Studies also show this ingredient to be a promising soothing ingredient for sensitive skin.
Learn more about Bifida Ferment LysateButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
- It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
- It is a humectant, which means that it helps attract moisture into the skin.
- It helps improve product application.
Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinNiacinamide has emerged as an all-star ingredient due to its many benefits.
It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.
Other benefits include smoothing wrinkles and minimizing redness.
The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.
Learn more about Niacinamide1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.
In products that are water-based, this ingredient can help stabilize perfumes and fragrances. It can also help make the texture of products softer and more smooth.
Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateSqualane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.
Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.
Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.
Research shows that squalane is non-irritating (even at 100% concentration).
In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.
The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.
Is squalane vegan?
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Learn more about SqualaneTromethamine is an aliphatic compound. An aliphatic compound is an organic compound with open-chained carbon atoms. It is synthetically created. Tromethamine is used to balance pH and improve texture.
As an emulsifier, Tromethamine prevents oil and water ingredients from separating. This helps stabilize the product and elongate a product's shelf life. Tromethamine also makes a product thicker.
Tromethamine helps balance the pH level of a product. Normal pH level of skin is slightly acidic (~4.75-5.5). The acidity of our skin is maintained by our glands and skin biome. Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.
Oral Tromethanmine is an anti-inflammatory drug but plays the role of masking, adding fragrance, and/or balancing pH in skincare.
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
Learn more about TromethamineEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumCarbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.
Carbomer is commonly found in many types of cosmetics products. It is found to be safe in concentrations up to 15%. However, a high amount of carbomer can cause pilling or balling up of products. Most products contain 1% of less of carbomer.
Ingredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
ma:nyo Bifida Biome Complex Ampoule 45 ingredients
Numbuzin No.3 Skin Softening Serum 28 ingredients
Reviews
Here's what our community thinks
ma:nyo Bifida Biome Complex Ampoule 45 ingredients
traceyy
WRP! I loved this serum. It was hydrating and sunk in well to my skin. My skin felt more plump and supple.
Numbuzin No.3 Skin Softening Serum 28 ingredients
cgi
numbuzin has become one of my favorite brands along with cosrx. this is one of the two serums i own from them, this and the no.5 goodbye blemish...
numbuzin has become one of my favorite brands along with cosrx. this is one of the two serums i own from them, this and the no.5 goodbye blemish serum.
i've only been using this since march of last year and it has been a game-changer ever since. i feel a bit dramatic when i say this, but i genuinely have seen a big difference in my skin using this compared to any other serum i've ever used. it blended in with my routine sooo unbelievably well. i don't know what type of witchcraft or sorcery is in this, but this product is a blessing and it's money VERY well-spent. beautiful bottle, it's like glass or something. it's a bit expensive, but you get so much product that'll last you way longer than a year. like i've had this since MARCH, and i still have over half the bottle left even though i use 3 drops every single night religiously.
it's hydrating, makes my skin very smooth (as it should), and has gone above and beyond in improving my skin texture. it miraculously decreased so many of the little bumps i get. it also absorbs very well under my base, literally just cleared my skin and boosted the glass skin look. i love this serum please buy it.
anniec
I had small bumps everywhere and my skin is quite sensitive but this worked very well. It made my skin almost completely smooth. The only thing it...
I had small bumps everywhere and my skin is quite sensitive but this worked very well. It made my skin almost completely smooth. The only thing it didn't fix was the stubborn closed comedones on my jaw and chin which wont go away no matter what.
