Versus

Heveblue Salmon Caring Centella Ampoule Versus VT Cosmetics PDRN Essence 100

Ampoule
Essence
Korean Brand South Korea
Korean Brand South Korea

Updated on March 09, 2025

Overview

What they are

These products are both reef safe . They have a total of 6 ingredients in common

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, common allergens, fragrances, parabens, silicones or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Benefits

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
PDRN Essence 100

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Solvent

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin. 

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol
Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Skin Conditioning

Sodium DNA is an emerging anti-aging ingredient.

It is created by taking deoxyribonucleic acid (DNA) and purifying it with sodium hydroxide.

The DNA is extracted from several different animal sources, including: calf thymus, the gonadic tissue of a male sturgeon, or herring / salmon sperm.

You have probably seen this ingredient in anti-aging skincare. But what is it?

DNA is composed of nucleotides, or chemical building blocks. Nucleotides include adenine (A), thymine (T), guanine (G), and cytosine (C). Talk about a flashback to biology! Nucleosides are formed from these nucleotides.

The science behind Sodium DNA is based on an ingredient called Polydeoxyribonucleotide or PDRN.

PDRN are DNA fragments mainly extracted from the sperm cells of trout or salmon. Meaning, PDRN can be derived from Sodium DNA.

PDRN consists of chains of nucleotides and nucleosides mentioned above. They can range anywhere from 80 - 2000 pairs.

Studies show PDRN has the following properties:

Further studies are needed to truly confirm this ingredients anti-aging ability (Remember, retinol has decades of research!).

When using this ingredient, is is best to ask a brand about the source of their Sodium DNA. You'll want to find products where the Sodium DNA is sourced from fish. Some Sodium DNA is derived from calf / cow thymus.

Learn more about Sodium Dna

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

53 Routines
38% use in am
62% use in pm
89% use every day
When to use See routines that use it ->
203 Routines
30% use in am
69% use in pm
84% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Heveblue Salmon Caring Centella Ampoule 25 ingredients

4.0 /5
from 1 rating
Absorbs Well (1) Hydrating (1)
lauryn's avatar

lauryn

6 months ago
Review

i love this whole line ! but i would say this and the moisturizer are my favorite. this ampoule is extremely calming and moisturizing and doesn’t break me out which is a win!

#hydrating
#absorbs well

VT Cosmetics PDRN Essence 100 31 ingredients

4.3 /5
from 4 ratings
Hydrating (3) Expensive (2) Heavy (2)
PNW1996's avatar

M X

2 months ago
Review

Great barrier restorative serum with some anti-aging benefit powered by PDRN, ginseng, and skin identical ingredients. Great anti-inflammatory. Not great for oily skin and there are better PDRN serums on the market for barrier restoration.

The PDRN in this product has low molecular weight, but this formulation has no delivery system for the PDRN and has only few super-mild penetration enhancers Show more

#heavy
#oily
rs12's avatar

R S

8 months ago
Review

I love it

#expensive
#hydrating
#light
#absorbs well