Hada Labo Overnight Treatment Smoothing Cream & Perfecting Serum Versus Biossance Squalane + Omega Repair Cream
This anti-aging night moisturizer is formulated around Squalane and Hydrolyzed Hyaluronic Acid to soften the look of wrinkles and hydrate skin.
This barrier-repair moisturizer is formulated around Squalane and Ceramide NP to strengthen the skin barrier and hydrate skin.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
HumectantButylene Glycol
HumectantDimethicone
EmollientPentylene Glycol
Skin ConditioningSqualane
EmollientTrehalose
HumectantTriethylhexanoin
MaskingAmmonium Acryloyldimethyltaurate/Vp Copolymer
Alcohol
AntimicrobialCaprylic/Capric Triglyceride
MaskingChlorphenesin
AntimicrobialDecylene Glycol
Skin ConditioningDimethicone Crosspolymer-3
Skin ConditioningDimethiconol
EmollientDisodium EDTA
ChelatingGlycine Soja Seed Extract
Skin ConditioningHydrolyzed Collagen
EmollientHydrolyzed Hyaluronic Acid
HumectantHydrolyzed Soy Protein
HumectantKjellmaniella Crassifolia Extract
EmollientLaureth-4
EmulsifyingLaureth-23
CleansingLonicera Japonica Flower Extract
Skin ConditioningPancratium Maritimum Extract
BleachingPEG-8 Methyl Ether Triethoxysilane
SurfactantPhenoxyethanol
PreservativePhysalis Angulata Extract
Skin ProtectingPullulan
Pvp
Emulsion StabilisingSodium Acetylated Hyaluronate
HumectantSodium Hyaluronate
HumectantTetrapeptide-5
Skin ConditioningTitanium Dioxide
Cosmetic ColorantTocopheryl Acetate
AntioxidantWater, Glycerin, Butylene Glycol, Dimethicone, Pentylene Glycol, Squalane, Trehalose, Triethylhexanoin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Alcohol, Caprylic/Capric Triglyceride, Chlorphenesin, Decylene Glycol, Dimethicone Crosspolymer-3, Dimethiconol, Disodium EDTA, Glycine Soja Seed Extract, Hydrolyzed Collagen, Hydrolyzed Hyaluronic Acid, Hydrolyzed Soy Protein, Kjellmaniella Crassifolia Extract, Laureth-4, Laureth-23, Lonicera Japonica Flower Extract, Pancratium Maritimum Extract, PEG-8 Methyl Ether Triethoxysilane, Phenoxyethanol, Physalis Angulata Extract, Pullulan, Pvp, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Tetrapeptide-5, Titanium Dioxide, Tocopheryl Acetate
Water
Skin ConditioningSqualane
EmollientGlycerin
HumectantCaprylic/Capric Triglyceride
MaskingIsoamyl Laurate
EmollientButyrospermum Parkii Butter
Skin ConditioningSorbitan Olivate
EmulsifyingCetearyl Olivate
Ceramide NP
Skin ConditioningJojoba Esters
EmollientSodium Hyaluronate
HumectantEuterpe Oleracea Sterols
Skin ConditioningLinoleic Acid
CleansingOleic Acid
EmollientLinolenic Acid
CleansingEthyl Linoleate
EmollientTocopherol
AntioxidantIsoamyl Cocoate
Cetyl Palmitate
EmollientSorbitan Palmitate
EmulsifyingCetearyl Alcohol
EmollientEthylhexylglycerin
Skin ConditioningCarbomer
Emulsion StabilisingSodium Hydroxide
BufferingPhenoxyethanol
PreservativeSodium Gluconate
ChelatingWater, Squalane, Glycerin, Caprylic/Capric Triglyceride, Isoamyl Laurate, Butyrospermum Parkii Butter, Sorbitan Olivate, Cetearyl Olivate, Ceramide NP, Jojoba Esters, Sodium Hyaluronate, Euterpe Oleracea Sterols, Linoleic Acid, Oleic Acid, Linolenic Acid, Ethyl Linoleate, Tocopherol, Isoamyl Cocoate, Cetyl Palmitate, Sorbitan Palmitate, Cetearyl Alcohol, Ethylhexylglycerin, Carbomer, Sodium Hydroxide, Phenoxyethanol, Sodium Gluconate
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Learn more about Caprylic/Capric TriglycerideGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPhenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateSqualane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Learn more about SqualaneWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water