Curology DayPrime Rx Versus Remedy For Dark Spots
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Azelaic Acid 15%
BufferingNiacinamide 4%
SmoothingPanthenol 1%
Skin Conditioning1,2-Hexanediol
Skin ConditioningButylene Glycol
HumectantCaprylyl Glycol
EmollientCeramide NP
Skin ConditioningCetearyl Olivate
Dimethicone
EmollientGlycerin
HumectantHydroxyacetophenone
AntioxidantOryza Sativa Starch
AbsorbentPolyacrylate Crosspolymer-6
Emulsion StabilisingPolyhydroxystearic Acid
EmulsifyingPolymethyl Methacrylate
Polymethylsilsesquioxane
Polysorbate 20
EmulsifyingPvp
Emulsion StabilisingSorbitan Olivate
EmulsifyingTrisodium Ethylenediamine Disuccinate
Water
Skin ConditioningPropylene Glycol
HumectantAzelaic Acid 15%, Niacinamide 4%, Panthenol 1%, 1,2-Hexanediol, Butylene Glycol, Caprylyl Glycol, Ceramide NP, Cetearyl Olivate, Dimethicone, Glycerin, Hydroxyacetophenone, Oryza Sativa Starch, Polyacrylate Crosspolymer-6, Polyhydroxystearic Acid, Polymethyl Methacrylate, Polymethylsilsesquioxane, Polysorbate 20, Pvp, Sorbitan Olivate, Trisodium Ethylenediamine Disuccinate, Water, Propylene Glycol
Water
Skin ConditioningGlycerin
HumectantNiacinamide
SmoothingSqualane
EmollientCetearyl Olivate
Dimethicone
EmollientTranexamic Acid
AstringentMandelic Acid
AntimicrobialSoy Acid
EmollientSorbitan Olivate
EmulsifyingGlutathione
Tetrahexyldecyl Ascorbate
AntioxidantGlycine Soja Seed Extract
Skin ConditioningKojic Dipalmitate
EmollientSilybum Marianum Fruit Extract
Skin ConditioningRetinol
Skin ConditioningCamellia Sinensis Leaf Extract
AntimicrobialCurcuma Longa Root Extract
MaskingAcetyl Glucosamine
Skin ConditioningCeramide NP
Skin ConditioningGlycyrrhiza Glabra Root Extract
BleachingPropanediol
SolventHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingIsohexadecane
EmollientCaesalpinia Spinosa Gum
Skin ConditioningCaprylic/Capric Triglyceride
MaskingPentylene Glycol
Skin ConditioningPolysorbate 60
EmulsifyingPolysorbate 20
EmulsifyingSorbitan Isostearate
EmulsifyingCetyl Palmitate
EmollientLaureth-23
CleansingTrideceth-6 Phosphate
EmulsifyingSodium Hydroxide
BufferingCaprylyl Glycol
EmollientHexylene Glycol
EmulsifyingPhenoxyethanol
PreservativeEthylhexylglycerin
Skin ConditioningSodium Benzoate
MaskingWater, Glycerin, Niacinamide, Squalane, Cetearyl Olivate, Dimethicone, Tranexamic Acid, Mandelic Acid, Soy Acid, Sorbitan Olivate, Glutathione, Tetrahexyldecyl Ascorbate, Glycine Soja Seed Extract, Kojic Dipalmitate, Silybum Marianum Fruit Extract, Retinol, Camellia Sinensis Leaf Extract, Curcuma Longa Root Extract, Acetyl Glucosamine, Ceramide NP, Glycyrrhiza Glabra Root Extract, Propanediol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Isohexadecane, Caesalpinia Spinosa Gum, Caprylic/Capric Triglyceride, Pentylene Glycol, Polysorbate 60, Polysorbate 20, Sorbitan Isostearate, Cetyl Palmitate, Laureth-23, Trideceth-6 Phosphate, Sodium Hydroxide, Caprylyl Glycol, Hexylene Glycol, Phenoxyethanol, Ethylhexylglycerin, Sodium Benzoate
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid or alcohol, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolCeramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Learn more about Ceramide NPCetearyl Olivate is an emulsifier and texture enhancer. It is derived from the fatty acids of olive oil and Cetearyl alcohol, and is biodegradable.
As an emulsifier, it is used to prevent oils and waters from separating. It can also
This ingredient is also known as part of Olivem 1000, with Sorbitan Olivate being the other part.
According to a manufacturer, this ingredient helps preserve the natural microbiome of skin. Having a healthy microbiome helps keep our skin healthy and protects against harmful bacteria.
Please note, having a healthy microbiome is different from fungal acne; a healthy microbiome includes small amounts of yeast that normally live on your skin without causing problems.
Fungal acne happens when one type of yeast (Malassezia) grows out of control. This is usually because it's feeding on certain oils or fatty acids. Due to the olive oil base, this ingredient may feed that yeast, so it may not be fungal acne safe.
Learn more about Cetearyl OlivateDimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamidePolysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.
It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.
The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.
Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).
True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.
Because it is derived from lauric acid, it may not be fungal acne safe.
Learn more about Polysorbate 20Sorbitan Olivate is created from the fatty acids in olive oil and sorbitol.
This ingredient is an oil in water emulsifier. It helps stabilize a product by preventing oils and waters from separating. Sorbitan Olivate also helps hydrate the skin.
This ingredient is also known as part of Olivem 1000, with Cetearyl Olivate being the other part.
According to a manufacturer, this ingredient helps preserve the natural microbiome of skin. Having a healthy microbiome helps keep our skin healthy and protects against harmful bacteria.
Please note, having a healthy microbiome is different from fungal acne; a healthy microbiome includes small amounts of yeast that normally live on your skin without causing problems.
Fungal acne happens when one type of yeast (Malassezia) grows out of control. This is usually because it's feeding on certain oils or fatty acids. Due to the olive oil base, this ingredient may not be fungal acne safe.
Learn more about Sorbitan OlivateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water