House Of PLLA+ Stem Cell Mist
A toner with 51 ingredients, including niacinamide, exfoliants, and peptides.
Overview
What it is
Toner with 51 ingredients that contains exfoliants, niacinamide and peptides
Cool Features
It is cruelty-free, fungal acne (malassezia) safe, and reef safe
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots
Free From
It doesn't contain any harsh alcohols, oils, parabens, silicones or sulfates
Fun facts
House Of PLLA+ is from Canada.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Calendula Officinalis Extract
Skin ConditioningWater
Skin ConditioningPropanediol
SolventRosa Damascena Flower Water
MaskingNiacinamide
Smoothing1,2-Hexanediol
Skin ConditioningButylene Glycol
HumectantPanthenol
Skin ConditioningHamamelis Virginiana Water
AstringentGlycereth-26
HumectantIsopentyldiol
HumectantPolylactic Acid
AbrasiveSh-Oligopeptide-1
Skin ConditioningSh-Oligopeptide-2
Skin ConditioningSh-Polypeptide-1
Skin ConditioningSh-Polypeptide-22
Skin ConditioningAloe Barbadensis Leaf Extract
EmollientNelumbo Nucifera Callus Culture Extract
AntimicrobialHydrolyzed Collagen
EmollientCaviar Extract
Skin ConditioningAureobasidium Pullulans Ferment Filtrate
HumectantAureobasidium Pullulans Ferment Extract
Cynanchum Atratum Extract
Skin ConditioningThiotaurine
AntioxidantAdenosine
Skin ConditioningRoyal Jelly Powder
Skin ConditioningRosa Roxburghii Fruit Extract
TonicCitric Acid
BufferingArtemisia Princeps Leaf Extract
Skin ConditioningOcimum Basilicum Extract
AntioxidantChamomilla Recutita Flower Extract
MaskingMentha Piperita Extract
CleansingEugenia Caryophyllus Flower Extract
AstringentJasminum Grandiflorum Flower Extract
MaskingLavandula Angustifolia Flower Extract
CleansingCitrus Aurantium Dulcis Flower Extract
Skin ConditioningOriganum Vulgare Extract
Skin ConditioningRosmarinus Officinalis Extract
AntimicrobialDextrin
AbsorbentThymus Quinquecostatus Extract
Skin ConditioningSalvia Officinalis Extract
AntimicrobialStevia Rebaudiana Extract
Trachyspermum Ammi Flower Extract
Tremella Fuciformis Extract
HumectantArtemisia Capillaris Extract
Scutellaria Baicalensis Root Extract
AstringentCentella Asiatica Extract
CleansingCoptis Japonica Root Extract
Skin ConditioningDisodium EDTA
Ethylhexylglycerin
Skin ConditioningCaprylyl Glycol
EmollientCalendula Officinalis Extract, Water, Propanediol, Rosa Damascena Flower Water, Niacinamide, 1,2-Hexanediol, Butylene Glycol, Panthenol, Hamamelis Virginiana Water, Glycereth-26, Isopentyldiol, Polylactic Acid, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-22, Aloe Barbadensis Leaf Extract, Nelumbo Nucifera Callus Culture Extract, Hydrolyzed Collagen, Caviar Extract, Aureobasidium Pullulans Ferment Filtrate, Aureobasidium Pullulans Ferment Extract, Cynanchum Atratum Extract, Thiotaurine, Adenosine, Royal Jelly Powder, Rosa Roxburghii Fruit Extract, Citric Acid, Artemisia Princeps Leaf Extract, Ocimum Basilicum Extract, Chamomilla Recutita Flower Extract, Mentha Piperita Extract, Eugenia Caryophyllus Flower Extract, Jasminum Grandiflorum Flower Extract, Lavandula Angustifolia Flower Extract, Citrus Aurantium Dulcis Flower Extract, Origanum Vulgare Extract, Rosmarinus Officinalis Extract, Dextrin, Thymus Quinquecostatus Extract, Salvia Officinalis Extract, Stevia Rebaudiana Extract, Trachyspermum Ammi Flower Extract, Tremella Fuciformis Extract, Artemisia Capillaris Extract, Scutellaria Baicalensis Root Extract, Centella Asiatica Extract, Coptis Japonica Root Extract, Disodium EDTA, Ethylhexylglycerin, Caprylyl Glycol
Key Ingredients
Benefits
Concerns
Ingredients Explained
Calendula Officinalis Extract comes from the common Marigold plant.
Marigold flowers contain flavonoids. Flavonoids are a group of substances found naturally in plants. They possess antioxidant and inflammation properties.
This ingredient may help soothe your skin by reducing inflammation. Emerging studies show it inhibits nitrous oxide production safely, therefore reducing inflammation.
Marigolds have been used in traditional medicine throughout Asia and Europe.
Learn more about Calendula Officinalis ExtractWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterPropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.Â
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolRosa Damascena Flower Water comes from the Damask rose. It is a dilluted version of the Rose Essential oil.
The Damask Roses' petals have antioxidant, antimicrobial, and fragrance compounds. Though antioxidants are great for soothing skin, the fragrance compounds can irritate it.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about Niacinamide1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.Â
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesÂ
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolPanthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolHamamelis Virginiana Water is made by distilling parts of the witch hazel plant. You can also call this ingredient "witch hazel water".
The name 'Hamamelis Virginiana Water' refers to the distillation product used in cosmetics. On the other hand, 'Witch Hazel' refers to the active drug ingredient.
Unless it is specified to be non-alcohol, many types of witch hazel ingredients are distilled in denatured alcohol.
Witch Hazel water is an astringent, anti-inflammatory antioxidant, and antibacterial ingredient.
It contains tannins. Tannins have a drying effect when used on skin by constricting proteins. The constriction also minimizes the appearance of pores.
Both the tannins and fragrance found in witch hazel may be skin-sensitizing.
Witch hazel water gets anti-inflammatory and antibacterial properties from its catechin and gallic acid content.
Indigenous groups have used witch hazel to help treat inflammation in North America for centuries.
Learn more about Hamamelis Virginiana WaterGlycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.
It is a humectant and helps add texture to products. It can make your product thicker.
As a humectant, it helps draw moisture from the air to your skin. This helps your skin stay hydrated.
Learn more about Glycereth-26Isopentyldiol is a synthetic solvent, humectant, and emollient.
Humectants have the ability to attract and hold water while emollients create a thin film to prevent water from evaporating. This combination keeps your skin and hair soft and hydrated. Plus, isopentyldiol does not leave a sticky feeling behind.
As a surfactant, isopentyldiol is a hydrotrope. Hydrotropes help surfactants (cleansing agents) dissolve into water.
According to the manufacturer, using this ingredient with sorbitol boosts skin hydration and helps close cuticles of damaged hair.
This ingredient is water-soluble.
Learn more about IsopentyldiolPolylactic Acid is an exfoliant.
sh-Oligopeptide-1 is a peptide found naturally in our bodies. Peptides are the building blocks for collagen and elastin in our skin.
In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.
Studies find EGF help with:
In South Korea and China, EGF is considered a controversial ingredient. The South Korean Ministry of Food and Drug Safety has cracked down on companies with products including EGF due to false advertisement claims.
According to Dr. Zoe Draelos, growth factors have some drawbacks:
There is also controversy surrounding growth factors. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.
Learn more about Sh-Oligopeptide-1This peptide has similar properties to Sh-Oligopeptide-1.
In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.
There is also controversy surrounding EGF. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.
Learn more about Sh-Oligopeptide-2Sh-Polypeptide-1 is a signal peptide that tells our cells to create more fibroblast cells. Fibroblasts maintain skin structure and plays a role in wound healing.
It is important to note this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.
Peptides are amino acids naturally found in your skin. These amino acids make up many proteins your skin uses. Collagen is made up of peptides. Collagen is responsible for keeping your skin plump and youthful.
As you age, your body naturally produces less collagen. Since peptides are the building blocks of collagen, it may have anti-aging effects.
Aloe Barbadensis Leaf Extract is an extract of the leaves of the aloe, Aloe barbadensis, Liliaceae.
Aloe is one of the most well-known natural soothing ingredients, and for good reason. It’s full of water and has a cooling, calming effect on the skin, especially when it’s sunburned, itchy, or irritated. Aloe also helps your skin stay hydrated and smooth by mimicking what healthy skin naturally produces. On top of that, it contains vitamins and nutrients that support skin recovery.Â
It doesn’t protect you from the sun, but it can help your skin bounce back after too much time in it.
Let’s get into the details:
Aloe contains antioxidant Vitamins A, C, and E, which help fight off free radicals (unstable molecules from things like pollution that can damage your skin).
It’s also rich in polysaccharides, which are natural sugars that help hydrate the skin by acting like the skin’s own moisturizing agents. These, along with other sugars like monosaccharides, help form a protective barrier that locks in moisture.
Aloe works as both a humectant and an emollient. That means it draws water into the skin (humectant) and helps trap it there (emollient), making it an effective natural moisturizer.
You’ll also find a mix of other skin-supporting ingredients in aloe, including folic acid, choline, calcium, amino acids, fatty acids, and even Vitamin B12.
Out of the 420+ species of aloe, Aloe barbadensis is the most widely used in skincare products thanks to its gentle yet effective properties.
There are over 420 species of aloe but Aloe Barbadensis is the most commonly used for topical products.
Learn more about Aloe Barbadensis Leaf ExtractNelumbo Nucifera Callus Culture Extract is an antioxidant.
Hydrolyzed collagen has a misleading name because it is actually a mixture of various proteins/peptides. This ingredient has skin hydrating properties.
Collagen is the most abundant type of structural protein found in your body. In your skin, it is responsible for keeping it firm and youthful.
Hydrolyzed Collagen is created by breaking up proteins into smaller peptide bonds. These peptides act as humectants and emollients.
Humectants are great at holding onto water, keeping skin hydrated. Emollients create a thin barrier on the skin to prevent moisture from escaping.
There is ongoing debate about whether hydrolyzed collagen works because it increases skin hydration. Skin hydration is also linked to elasticity and the appearance of wrinkles.
Collagen or peptide ingredients can be used in the morning or night. They will not increase sun sensitivity, but you should always wear sunscreen during the day.
According to a manufacturer, this ingredient is a great hair conditioner as well.
This ingredient can be extracted from different sources, including:
Vegan collagen is derived from yeast, bacteria, or plant sources. Vegan collagen would go by a different INCI name, such as hydrolyzed soy protein.
The results are varied.
A study from 2021 found hydrolyzed collagen increased elasticity and improved wrinkles in 1,125 participants between age 20 and 70. Another study found increased skin thickness in participants between the ages of 45 to 59.
However, It is difficult to prove that oral collagen will end up working on your skin. Many of the studies using hydrolyzed collagen also add several vitamins and nutrients into the test mixture as well.
Further studies are needed at this time.
Learn more about Hydrolyzed CollagenCaviar extract comes from the roe (or internal egg) of fish. This ingredient is rich in Omega-3's, antioxidants, amino acids, vitamin B12, iron, and magnesium. These components give it skin conditioning properties.
A study from 2020 found a component of caviar extract, docosahexaenoic acid (DHA), protects skin against UV-B skin aging.
Unless a company discloses more information, the source of this ingredient is unknown. It can be extracted from sturgeon, paddlefish, salmon, trout, carp, or more. According to animal organizations, true caviar is only extracted from the sturgeon fish.
Caviar can be extracted from the fish using several methods:
Learn more about Caviar ExtractWe don't have a description for Aureobasidium Pullulans Ferment Filtrate yet.
We don't have a description for Aureobasidium Pullulans Ferment Extract yet.
We don't have a description for Cynanchum Atratum Extract yet.
Thiotaurine is an antioxidant.
Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.
Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.
Studies have found adenosine may also help with wound healing.
In skincare products, Adenosine is usually derived from yeast.
Learn more about AdenosineRoyal Jelly Powder comes from a secretion made by worker honeybees. This secretion is white and described as creamy.
We don't have a description for Rosa Roxburghii Fruit Extract yet.
Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Read more about some other popular AHA's here:
Learn more about Citric AcidThis leaf extract comes from the Asian mugwort. It has antioxidant and anti-inflammatory properties.
Fun fact: This flower is part of the sunflower family.
Ocimum Basilicum Extract is an antioxidant.
Chamomilla Recutita Flower Extract comes from the Chamomile flower.
Chamomile is rich in antioxidants and has anti-inflammatory properties. Several compounds found in chamomile help with soothing, such as bisbolol.
Antioxidant components in chamomile make it an effective ingredient to help slow the signs of aging. Antioxidants help fight free-radical molecules, or molecules that may damage your skin.
Essential oils from chamomile have been found to improve wound healing due to its antimicrobial properties.
Ancient Greeks and Egyptians used Chamomile to treat skin redness and dryness. Chamomile has also been used to help treat stomach issues.
Learn more about Chamomilla Recutita Flower ExtractWe don't have a description for Mentha Piperita Extract yet.
This ingredient is also known as clove flower extract and Syzygium aromaticum.
Jasminum Grandiflorum Flower Extract is a fragrance.
Lavandula Angustifolia Flower Extract comes from the lavender plant.
Many components of lavender flowers are antioxidants, such as ferulic acid, caffeic acid, and several flavonoids.
Traditional Iranian folk medicine uses Lavender extract to help treat inflammation.
Lavender extract may have a scent.
It contains linalool, a known allergen. However, lavender extract contains less linalool than lavender essential oil.
Learn more about Lavandula Angustifolia Flower ExtractWe don't have a description for Citrus Aurantium Dulcis Flower Extract yet.
We don't have a description for Origanum Vulgare Extract yet.
Rosemary extract has antioxidant, anti-inflammatory, anti-bacterial, and astringent properties.
This ingredient has a natural fragrance due its small component of rosemary oil. The antioxidant properties from its rosmarinic acid, flavone, and phenolic acids.
Dextrin is used to thicken a product and helps bind ingredients together. It is created from starch and glycogen.
As an emulsifier, dextrin prevents ingredients from separating. This helps elongate a product's shelf life.
Studies show coating UV filters with dextrin prevents these ingredients from being absorbed. This helps UV ingredients last longer on the skin.
Learn more about DextrinWe don't have a description for Thymus Quinquecostatus Extract yet.
Salvia, or sage, extract is a culinary and medicinal herb with antibacterial, antioxidant, and soothing properties.
This ingredient is made up of 75-90% ursolic acid, a potent antioxidant and anti-inflammatory compound.
Fun fact: Sage is a member of the mint family.
Learn more about Salvia Officinalis ExtractWe don't have a description for Stevia Rebaudiana Extract yet.
We don't have a description for Trachyspermum Ammi Flower Extract yet.
Tremella Fuciformis Extract comes from the tremella fuciformis mushroom, also known as snow mushroom or white jelly mushroom.
The snow mushroom has moisturizing and antioxidant properties.
Snow mushroom is rich in polysaccharides, giving it moisturizing benefits. As a humectant, snow mushroom helps draw moisture from the air to the skin. Polysaccharides are able to mimic our skin's natural carbohydrates to help the skin retain water.
Snow mushroom has been shown to help with anti-aging due to its antioxidants. It increases the presence of superoxide dismutase in our brain and liver. Superoxide is a by-product of oxygen metabolism. It left unregulated, superoxide causes cell damage. Thus, superoxide dismutase acts as an antioxidant to protect our living cells.
Another study from 2016 showed snow mushroom extract blocks the skin from creating melanin when exposed to UVB. Thus, it may help protect against the signs of aging from sun exposure. However, more studies are needed to confirm this. Another study from 2021 found snow mushroom to protect against UVA damage as well.
This white mushroom is native to Asian countries such as China, Korea, Japan, and Thailand. It is a common ingredient in traditional Chinese cuisine and medicine.
Learn more about Tremella Fuciformis ExtractThis flowering plant is more commonly known as Capillary wormwood.
According to a manufacturer, the flowers of this plant are used for their anti-inflammation and moisturizing properties.
Scutellaria Baicalensis Root Extract comes from the Baikal skullcap or Chinese skullcap plant. This plant is native to Northeast Asia and can be found in China, Mongolia, Korea, and Siberia.
In cosmetics, Scutellaria Baicalensis Root Extract provides antioxidant and anti-inflammatory benefits. This is due to the flavonoid composition of Scutellaria Baicalensis Root Extract.
In Chinese traditional folk medicine, Scutellaria Baicalensis Root Extract is used to help treat lung issues and hypertension.
Learn more about Scutellaria Baicalensis Root ExtractCentella Asiatica Extract (Centella) is derived from an herb native to Southeast Asia. It is famous for its anti-inflammatory and soothing properties.
Centella is rich in antioxidants and amino acids, such as Madecassic Acid and Asiaticoside.
Studies show the compounds in centella help with:
The combination of all these properties makes centella effective at soothing, hydrating, and protecting the skin.
Other great components of centella include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.
Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.
Learn more about Centella Asiatica ExtractCoptis Japonica Root Extract, also known as Japanese Goldthread, is a traditional East Asian herb. It is prized for its anti-inflammatory, antioxidant, and antimicrobial properties.
That’s not all - research in the International Journal of Cosmetic Science found that its active compound, berberine, may help reduce fat accumulation and slow down fat cell development.
This makes it a promising ingredient for slimming and anti-cellulite products!
Learn more about Coptis Japonica Root ExtractDisodium EDTA plays a role in making products more stable by aiding other preservatives.
It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.
Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.
Learn more about Disodium EDTAEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.
Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.
This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.
Learn more about Caprylyl GlycolReviews
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Where it's from
House Of PLLA+ is a Canadian brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated December 10, 2025 • Added by Suzamazen