12Cosme NMN Executive Key Cleansing
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12Cosme NMN Executive Key Cleansing

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Overview

What it is

Face cleanser with 32 ingredients that contains exfoliants and niacinamide

Cool Features

It is reef safe

Suited For

It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

It doesn't contain any common allergens, oils, parabens, silicones or sulfates

Fun facts

12Cosme is from Japan.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

About this product

Ingredients List

Dive into the full list of ingredients.

Key Ingredients

Benefits

Concerns

Ingredients Explained

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.
  • It has mild preservative properties.

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Peg-7 Glyceryl Cocoate is created from polyethylene glycol and fatty acids from coconut oil.

It is a synthetic polymer with emulsifying and cleansing properties.

As an emulsifier, Peg-7 Glyceryl Cocoate prevents ingredients such as oils and water from separating. It also helps rinse away oils, dirt, and pollutants from skin.

Peg-7 Glyceryl Cocoate may not be fungal acne safe. It can also dry out skin.

Learn more about PEG-7 Glyceryl Cocoate
Humectant, Skin Conditioning

Betaine is a common humectant (a substance that promotes retention of moisture). It's known to be gentle on the skin and can help balance hydration.

This ingredient is best for improving hydration and soothing irritated skin. Studies also show it helps even out skin tone.

Fun fact: Betaine is naturally created in the skin and body. The kind found within cosmetic products can be either plant-derived or synthetic.

Learn more about Betaine

Cetyl Ethylhexanoate is an emollient ester. It comes from cetearyl alcohol and 2-ethylhexanoic acid.

Cetyl Ethylhexanoate is an emollient that adds a velvety feel to skin without being greasy or oily. Emollients help trap moisture into your skin, keeping your skin soft and hydrated.

Humectant, Skin Conditioning

Glyceryl Glucoside is made from glycerol and glucose.

It is a humectant. Humectants help hydrate your skin by drawing moisture to it from the air.

Some foods that contain glyceryl glucoside include sake, miso, and wines.

Learn more about Glyceryl Glucoside
Emulsion Stabilising

We don't have a description for Glycosyl Trehalose yet.

Nicotinamide Mononucleotide is an antioxidant.

Smoothing

Niacinamide has emerged as an all-star ingredient due to its many benefits.

It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.

Other benefits include smoothing wrinkles and minimizing redness.

The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.

Learn more about Niacinamide
Skin Conditioning, Tonic

We don't have a description for Syringa Vulgaris Extract yet.

Skin Conditioning

We don't have a description for Soluble Proteoglycan yet.

Humectant, Skin Conditioning

Dipotassium Glycyrrhizate comes from licorice root.

Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties.

One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.

Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.

Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.

Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.

Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.

Learn more about Dipotassium Glycyrrhizate
Skin Conditioning, Skin Protecting, Soothing

Allantoin plays a role in soothing and moisturizing the skin. Because of this, it is often added to products with strong active ingredients.

Some studies have shown this ingredient can promote wound healing with higher concentrations.

Allantoin is derived from the comfrey plant but produced synthetically for cosmetic products to ensure purity.

Learn more about Allantoin
Skin Conditioning

We don't have a description for Gentiana Lutea Root Extract yet.

Palmitoyl Olive Leaf Extract is an antioxidant.

We don't have a description for Angelica Keiskei Leaf/Stem Extract yet.

Skin Conditioning, Tonic

We don't have a description for Phellodendron Amurense Bark Extract yet.

We don't have a description for Perilla Ocymoides Leaf Extract yet.

Humectant

We don't have a description for Eel Extract yet.

Perfuming, Skin Conditioning

Melaleuca Alternifolia Leaf Extract comes from the Tea Tree, Melaleuca alternifolia, Myrtaceae. This tea tree is native to Australia.

Tea Leaf extract contains antimicrobial and anti-acne properties.

Tea tree extract is fragrant and contains volatiles such as linalool and limonene. These fragrance and terpinen components can cause skin sensitivity.

Learn more about the benefits of Tea Tree Oil here.

Learn more about Melaleuca Alternifolia Leaf Extract

We don't have a description for Pueraria Lobata Root Extract yet.

Abrasive, Skin Conditioning

Secale Cereale Seed Extract is an exfoliant.

Skin Conditioning

Chlorella Vulgaris Extract comes from a green microalga. It is hydrating and contains antioxidants.

Studies also show Chlorella Vulgaris may help in rebuilding collagen and elastin. This ingredient is made up of lipids, carbohydrates, and chlorophyll.

Fun fact: This ingredient is commonly used as food additive in Japan.

Learn more about Chlorella Vulgaris Extract
Emollient, Humectant, Skin Conditioning

Aloe Barbadensis Leaf Extract is an extract of the leaves of the aloe, Aloe barbadensis, Liliaceae.

You may know Aloe to be a good sunburn reliever and inflammation reducer. This is because it contains many components that are known to help reduce irritation and itchiness. These include vitamins, amino acids, polysaccharides, and more. The high water content of aloe also helps give a cooling effect.

Aloe contains the antioxidants Vitamins A, C, and E. These vitamins neutralize free radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.

The aloe plant is naturally abundant in polysaccharides, a carbohydrate made of sugar molecules. Polysaccharides help hydrate your skin by mimicking your skin's natural carbohydrates.

As it is easily absorbed by the skin, aloe is a great moisturizer. It is both a humectant and emollient. Emollients help trap moisture in your skin, keeping your skin soft. Humectants draw water from the air to your skin.

Other components of aloe include sugars such as monosaccharides and polysaccharides, folic acid, choline, many common minerals such as calcium, fatty acids, amino acids, and Vitamin B12.

Aloe does not protect against UV rays, despite it soothing sunburns.

There are over 420 species of aloe but Aloe Barbadensis is the most commonly used for topical products.

Learn more about Aloe Barbadensis Leaf Extract

Carrageenan comes from red seaweed or algae. It is made up of polysaccharides and a highly flexible compound. Red algae cell walls are rich in carrageenan.

In cosmetics, it helps to thicken the texture. Studies show carrageenan extracted from red algae possess antioxidant properties. Components found in carrageenan include: lipids, fatty acids, Vitamin E, proteins, and several amino acids.

Learn more about different types of algae.

Carrageenan is also commonly used in medicine and food. It is a vegan alternative to animal-based gelatin.

Learn more about Carrageenan

We don't have a description for Hydrogenated Starch Hydrolysate yet.

Emulsion Stabilising, Gel Forming

Carbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

Potassium hydroxide is commonly known as caustic potash. It is used to fix the pH of a product or as a cleaning agent in soap. In cleansers, it is used for the saponification of oils.

Sapnification is the process of creating fatty acid metal salts from triglycerides and a strong base. During this process, Potassium Hydroxide is used up and is not present in the final product.

Using high concentrations of Potassium Hydroxide have shown to irritate the skin.

Learn more about Potassium Hydroxide
Antimicrobial, Astringent, Masking

Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.

This ingredient gets a bad rep because it is irritating and drying - mostly due to its astringent property. Astringents draw out natural oils in tissue, constricting pores and leaving your skin dried out.

However, alcohol denat. is not all that bad.

Due to its low molecular weight, alcohol denat. tends to evaporate quickly. One study on pig skin found half of applied alcohol evaporated in 10 seconds and less than 3% stayed on skin.

This also helps other ingredients become better absorbed upon application.

Studies are conflicted about whether this ingredient causes skin dehydration. One study from 2005 found adding emollients to propanol-based sanitizer decreased skin dryness and irritation. Another study found irritation only occurs if your skin is already damaged.

Small amounts of alcohol are generally tolerated by oily skin or people who live in humid environments.

The rule of thumb is if this alcohol is near the end of an ingredients list, it will probably not affect your skin much.

Also...

This ingredient has antimicrobial and solvent properties.

The antimicrobial property helps preserve products and increase their shelf life. As a solvent, it helps dissolve other ingredients.

Other types of astringent alcohols include:

Learn more about Alcohol Denat.
Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

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· Published April 13, 2025 Added by ktmgiu