Olay Regenerist Retinol 24 + Peptide Night Moisturizer Versus Clinique Smart Night™ Custom-Repair Moisturizer
This anti-aging night moisturizer is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture.
This anti-aging night moisturizer is formulated around Acetyl Hexapeptide-8 and Aminopropyl Ascorbyl Phosphate to soften the look of wrinkles.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningDimethicone
EmollientGlycerin
HumectantTapioca Starch
Dimethicone Crosspolymer
Emulsion StabilisingRetinol
Skin ConditioningRetinyl Propionate
Skin ConditioningNiacinamide
SmoothingPalmitoyl Pentapeptide-4
Skin ConditioningPolyacrylamide
C13-14 Isoparaffin
EmollientDMDM Hydantoin
PreservativePolysorbate 20
EmulsifyingLaureth-4
EmulsifyingAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingLaureth-7
EmulsifyingDimethiconol
EmollientPolymethylsilsesquioxane
Aminomethyl Propanol
BufferingTitanium Dioxide
Cosmetic ColorantDisodium EDTA
Iodopropynyl Butylcarbamate
PreservativeCaprylic/Capric Triglyceride
MaskingWater, Dimethicone, Glycerin, Tapioca Starch, Dimethicone Crosspolymer, Retinol, Retinyl Propionate, Niacinamide, Palmitoyl Pentapeptide-4, Polyacrylamide, C13-14 Isoparaffin, DMDM Hydantoin, Polysorbate 20, Laureth-4, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Laureth-7, Dimethiconol, Polymethylsilsesquioxane, Aminomethyl Propanol, Titanium Dioxide, Disodium EDTA, Iodopropynyl Butylcarbamate, Caprylic/Capric Triglyceride
Water
Skin ConditioningCaprylic/Capric/Myristic/Stearic Triglyceride
EmollientPetrolatum
EmollientGlycerin
HumectantHexyldecyl Stearate
EmollientButylene Glycol
HumectantDimethicone
EmollientGlycereth-26
HumectantGlyceryl Stearate
EmollientPEG-100 Stearate
SurfactantCetearyl Alcohol
EmollientCentaurium Erythraea Extract
Skin ConditioningAlgae Extract
EmollientMicrococcus Lysate
Skin ConditioningGlycine Soja Protein
EmulsifyingHydrolyzed Soy Protein
HumectantFaex Extract
Skin ConditioningSaccharomyces/Xylinum/Black Tea Ferment
Skin ConditioningSigesbeckia Orientalis Extract
Skin ConditioningCaffeine
Skin ConditioningBiotin
AntiseborrhoeicErgothioneine
AntioxidantAcetyl Hexapeptide-8
HumectantSoy Amino Acids
Skin ConditioningAminopropyl Ascorbyl Phosphate
AntioxidantAstrocaryum Murumuru Seed Butter
EmollientTocopheryl Acetate
AntioxidantWhey Protein
Skin ConditioningCetearyl Glucoside
EmulsifyingIsohexadecane
EmollientCaprylyl Glycol
EmollientAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingAcetyl Glucosamine
Skin ConditioningSodium Hyaluronate
HumectantMyristyl Alcohol
EmollientTromethamine
BufferingPolysorbate 80
EmulsifyingAcrylamide/Sodium Acryloyldimethyltaurate Copolymer
Emulsion StabilisingCitric Acid
BufferingHexylene Glycol
EmulsifyingLecithin
EmollientSodium Benzoate
MaskingCalcium Chloride
AstringentHydroxyethylcellulose
Emulsion StabilisingDisodium EDTA
Sodium Citrate
BufferingPotassium Sorbate
PreservativePhenoxyethanol
PreservativeWater, Caprylic/Capric/Myristic/Stearic Triglyceride, Petrolatum, Glycerin, Hexyldecyl Stearate, Butylene Glycol, Dimethicone, Glycereth-26, Glyceryl Stearate, PEG-100 Stearate, Cetearyl Alcohol, Centaurium Erythraea Extract, Algae Extract, Micrococcus Lysate, Glycine Soja Protein, Hydrolyzed Soy Protein, Faex Extract, Saccharomyces/Xylinum/Black Tea Ferment, Sigesbeckia Orientalis Extract, Caffeine, Biotin, Ergothioneine, Acetyl Hexapeptide-8, Soy Amino Acids, Aminopropyl Ascorbyl Phosphate, Astrocaryum Murumuru Seed Butter, Tocopheryl Acetate, Whey Protein, Cetearyl Glucoside, Isohexadecane, Caprylyl Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Acetyl Glucosamine, Sodium Hyaluronate, Myristyl Alcohol, Tromethamine, Polysorbate 80, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Citric Acid, Hexylene Glycol, Lecithin, Sodium Benzoate, Calcium Chloride, Hydroxyethylcellulose, Disodium EDTA, Sodium Citrate, Potassium Sorbate, Phenoxyethanol
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
Learn more about Acrylates/C10-30 Alkyl Acrylate CrosspolymerDimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water