MediCube Txa Niacinamide 15% Serum Versus COSRX The Alpha-Arbutin 2 Discoloration Care Serum
Updated on February 21, 2025
Overview
What they are
These products are both cruelty-free and reef safe serums. They have a total of 18 ingredients in common
Cool Features
They both contain hyaluronic acid and niacinamide
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots
Free From
They both do not contain any fragrances, parabens or sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
MediCube Txa Niacinamide 15% Serum 39 ingredients
COSRX The Alpha-Arbutin 2 Discoloration Care Serum 38 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
MediCube Txa Niacinamide 15% Serum 39 ingredients
COSRX The Alpha-Arbutin 2 Discoloration Care Serum 38 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolTranexamic Acid is best used for treating hyperpigmentation, discoloration, and melasma. It can also help build a stronger skin barrier.
Once applied, Tranexamic Acid starts decreasing inflammation from UV exposure. Tranexamic Acid also prevents our skin cells from meeting the pigment production cells.
Its brightening property makes it great at reducing the appearance of acne scars and marks.
Fun fact: Tranexamic Acid is also a medication used to reduce heavy bleeding.
This acid is derived from lysine, an amino acid.
Learn more about Tranexamic AcidWe don't have a description for Diethoxyethyl Succinate yet.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumDisodium EDTA plays a role in making products more stable by aiding other preservatives.
It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.
Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.
Learn more about Disodium EDTA1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.Â
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesÂ
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolFerulic Acid is a plant based antioxidant. By fighting free-radicals, ferulic acid can help reduce the formation of fine lines and hyperpigmentation.
When used with Vitamin C, Ferulic Acid has shown to prevent Vitamin C from breaking down. In other words, it acts as a stabilizer.
Ferulic Acid is sometimes used to preserve food. Foods containing Ferulic Acid include: oats, rice, eggplant, citrus.
In medicine, Ferulic Acid is being studied for helping with diabetes, Alzheimer's, and cardiovascular diseases.
Learn more about Ferulic AcidGlutathione is an antioxidant naturally found in our bodies. It is made up of three amino acids: glycine, cysteine, and glutamic acid.
As an antioxidant, it prevents oxidative damage to parts of our cell.
While glutathione is said to help with fading dark spots, the results from research are inconclusive. Further studies are needed. With that said, gluthatione has been shown to protect our skin from UV-B induced damage.
This ingredient is naturally occurring in plants, animals, fungi, and some bacteria.
Learn more about GlutathioneHydrolyzed Hyaluronic Acid is a form of hyaluronic acid. It is created by the hydrolysis of hyaluronic acid with a high molecular weight. Once created, Hydrolyzed Hyaluronic Acid has a low molecular weight.
Low molecular weight HA has been shown to hydrate and increase elasticity of the skin. Increasing elasticity is also associated with reduction of wrinkle depth.
One study found topical low molecular weight hyaluronic acid may be considered for the treatment of rosacea in the adult population. However, we always recommend speaking with a professional about your skin concerns.
Hyaluronic acids are a humectant. This means they draw moisture from the air. Hyaluronic acids help moisturize, soothe, and protect the skin.
Read more about other common forms of hyaluronic acid:
Learn more about Hydrolyzed Hyaluronic AcidHyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.
This ingredient helps hydrate, soothe, and protect the skin.
What makes hyaluronic acid so hydrating? It has the capacity to bind or hold large amounts of water.
Fun fact: It is already naturally found in our bodies, such as the fluids of our eyes and our joints.
Studies find this ingredient to have anti-inflammatory and anti-microbial properties. This can help speed up wound-healing.
Hyaluronic acid can be irritating if the molecule has a low-molecular weight, or if the molecules are small.
One study found low-molecular weight hyaluronic acid to be pro-inflammatory, meaning some people may experience irritation. This is because our bodies use hyaluronic acid in the wound-healing process to signal to our bodies, via irritation, that something needs healing.
The same study found high-molecular weight hyaluronic acid to be anti-inflammatory.
These are some other common types of Hyaluronic Acid:
Learn more about Hyaluronic AcidSodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateSodium Hyaluronate Crosspolymer is a type of hyaluronic acid. In fact, it is modified version of hyaluronic acid.
The structure of Sodium Hyaluronate Crosspolymer allows it to stay in the skin's top layer for a longer period of time. This allows for even more hydration and humectant action than hyaluronic acid.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium Hyaluronate CrosspolymerSodium Acetylated Hyaluronate is a type of Hyaluronic Acid.
Hyaluronic Acids help moisturize, soothe, and protect the skin.
Read about common types of Hyaluronic Acid here: Sodium Hyaluronate Hydrolyzed Hyaluronic Acid Hyaluronic Acid
Learn more about Sodium Acetylated HyaluronateIngredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
MediCube Txa Niacinamide 15% Serum 39 ingredients
COSRX The Alpha-Arbutin 2 Discoloration Care Serum 38 ingredients


Reviews
Here's what our community thinks
MediCube Txa Niacinamide 15% Serum 39 ingredients
COSRX The Alpha-Arbutin 2 Discoloration Care Serum 38 ingredients
I really wanted this to work, and I gave it three attempts over a few months, but every time I used it it gave me irritation in the form of little red dots on my upper cheeks and nose (I never get acne in these areas). It may just be too strong for me.