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Overview
What they are
These products are both reef safe . They have a total of 13 ingredients in common
Cool Features
They both contain hyaluronic acid
Suited For
They're both likely to be good for anti aging, dry skin, brightening skin, scar healing and dark spots
Free From
They both do not contain any common allergens, parabens or sulfates
What's Inside
They both contain harsh alcohols, fragrances and silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
MediCube Triple Collagen Serum 28 ingredients
Ipse Cosmetic Botonix Age-Defying Ampoule 42 ingredients
At a glance
Click on any of the items below to learn more
MediCube Triple Collagen Serum 28 ingredients
Ipse Cosmetic Botonix Age-Defying Ampoule 42 ingredients
Notable Ingredients
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Benefits
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Concerns
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Ingredients Side-by-side
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.
5 Concerns
Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.
6 Benefits
Niacinamide has emerged as an all-star ingredient due to its many benefits.
Glycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.
Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.
Hydrolyzed collagen has a misleading name because it is actually a mixture of various proteins/peptides. This ingredient has skin hydrating properties.
4 Benefits May cause irritation
Hyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.
Hydrolyzed Hyaluronic Acid is a form of hyaluronic acid. It is created by the hydrolysis of hyaluronic acid with a high molecular weight. Once created, Hydrolyzed Hyaluronic Acid has a low molecular weight.
Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Soluble Collagen can help to reduce the effects of aging.
Collagen is the most abundant type of structural protein found in your body. In your skin, it is responsible for keeping it firm and youthful.
Atelocollagen can help to reduce the effects of aging.
Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.
Cyclopentasiloxane is a silicone used to improve texture and trap moisture. An easier name for this is D5.
Trehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.
Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.
Cetearyl Olivate is an emulsifier and texture enhancer. It is derived from the fatty acids of olive oil and Cetearyl alcohol, and is biodegradable.
Tromethamine is an aliphatic compound. An aliphatic compound is an organic compound with open-chained carbon atoms. It is synthetically created. Tromethamine is used to balance pH and improve texture.
Cyclohexasiloxane is a type of silicone more commonly known as D6. It is an emollient and solvent.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
Disodium EDTA plays a role in making products more stable by aiding other preservatives.
Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.
2 Concerns
Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Sea Water, Glycerin, Butylene Glycol, Cetyl Ethylhexanoate, 1,2-Hexanediol, Alcohol Denat., Niacinamide, Glycereth-26, Adenosine, Hydrolyzed Collagen, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Soluble Collagen, Collagen Extract, Atelocollagen, Propanediol, Cyclopentasiloxane, Trehalose, Carbomer, Cetearyl Olivate, Tromethamine, Cyclohexasiloxane, Sorbitan Olivate, Ethylhexylglycerin, Disodium EDTA, Dimethicone, Parfum
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
Cyclopentasiloxane is a silicone used to improve texture and trap moisture. An easier name for this is D5.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
5 Concerns
Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.
Betaine is a common humectant (a substance that promotes retention of moisture). It's known to be gentle on the skin and can help balance hydration.
Cyclohexasiloxane is a type of silicone more commonly known as D6. It is an emollient and solvent.
Methyl Gluceth-20 is a humectant. Humectants help draw moisture from the air to your skin.
Dipropylene Glycol is a synthetically created stabilizer and solvent. It is a part of the glycol class in the alcohol family.
Glycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.
2 Concerns
Silica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.
Not safe for Fungal Acne
Peg-60 Hydrogenated Castor Oil comes from hydrogenated castor oil. It is a solubilizer and emulsifier.
Polyacrylate-13 is a type of acrylate polymer. Acrylate polymers are commonly used as adhesives in cosmetics.
Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol.
Dimethiconol is a silicone that resembles the popular dimethicone. Like other silicones, it is an emollient. Emollients create a thin film on skin to prevent moisture from escaping.
Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
Helps hydrate Dry Skin Not safe for Fungal Acne
Argania Spinosa Kernel Oil is derived from the kernels of the argania spinosa tree. You may know it as argan oil.
Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.
2 Concerns
Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
4 Benefits
Ceramide NS is a type of Ceramide. Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.
1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.
Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
Sorbitan Isostearate is an emulsifer and cleaning agent. It is created from isostearic acid and sorbitol.
Disodium EDTA plays a role in making products more stable by aiding other preservatives.
Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Beta Vulgaris Extract comes from the beet root plant. Beet Root has high Vitamin C content.
Citrus Limon Fruit Extract comes from lemons. While lemon extract is exfoliating and antimicrobial, it can also cause skin sensitivity.
Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.
Acetyl Hexapeptide-8 is a peptide. A common name for this peptide is Argireline.
Water, Glycerin, Cyclopentasiloxane, Butylene Glycol, Glycol, Alcohol Denat., Betaine, Cyclohexasiloxane, Methyl Gluceth-20, Dipropylene Glycol, Glycereth-26, Silica, Octyldodeceth-16, Peg-60 Hydrogenated Castor Oil, Polyacrylate-13, Polyisobutene, Chlorphenesin, Dimethiconol, Caprylyl Glycol, Ethylhexylglycerin, Argania Spinosa Kernel Oil, Carbomer, Parfum, Arginine, Xanthan Gum, Ceramide Ns, 1,2-Hexanediol, Adenosine, Polysorbate 20, Sorbitan Isostearate, Caramel, Disodium EDTA, Dipotassium Glycyrrhizate, Sodium Hyaluronate, Cyclotetrasiloxane, Beta Vulgaris Extract, CI 77480, Citrus Limon Fruit Extract, Tripropylene Glycol, Propylene Glycol, Eleutherococcus Senticosus Root Extract, Acetyl Hexapeptide-8
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
- It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
- It is a humectant, which means that it helps attract moisture into the skin.
- It helps improve product application.
Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.
1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.
In products that are water-based, this ingredient can help stabilize perfumes and fragrances. It can also help make the texture of products softer and more smooth.
Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.
This ingredient gets a bad rep because it is irritating and drying - mostly due to its astringent property. Astringents draw out natural oils in tissue, constricting pores and leaving your skin dried out.
However, alcohol denat. is not all that bad.
Due to its low molecular weight, alcohol denat. tends to evaporate quickly. One study on pig skin found half of applied alcohol evaporated in 10 seconds and less than 3% stayed on skin.
This also helps other ingredients become better absorbed upon application.
Studies are conflicted about whether this ingredient causes skin dehydration. One study from 2005 found adding emollients to propanol-based sanitizer decreased skin dryness and irritation. Another study found irritation only occurs if your skin is already damaged.
Small amounts of alcohol are generally tolerated by oily skin or people who live in humid environments.
The rule of thumb is if this alcohol is near the end of an ingredients list, it will probably not affect your skin much.
Also...
This ingredient has antimicrobial and solvent properties.
The antimicrobial property helps preserve products and increase their shelf life. As a solvent, it helps dissolve other ingredients.
Other types of astringent alcohols include:
Learn more about Alcohol Denat.Glycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.
It is a humectant and helps add texture to products. It can make your product thicker.
As a humectant, it helps draw moisture from the air to your skin. This helps your skin stay hydrated.
Learn more about Glycereth-26Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.
Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.
Studies have found adenosine may also help with wound healing.
In skincare products, Adenosine is usually derived from yeast.
Learn more about AdenosineSodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateCyclopentasiloxane is a silicone used to improve texture and trap moisture. An easier name for this is D5.
D5 is considered lightweight and volatile. Volatile means it evaporates quickly after application. Once evaporated, D5 leaves a thin barrier that helps keep skin hydrated.
D5 is an emollient. Emollients help soften the skin and prevent water loss. Silicones create a silky texture in products. D5 helps other ingredients become more spreadable.
Studies show D5 is safe to use in skincare products. We recommend speaking with a skincare professional if you have concerns.
Learn more about CyclopentasiloxaneCarbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.
Carbomer is commonly found in many types of cosmetics products. It is found to be safe in concentrations up to 15%. However, a high amount of carbomer can cause pilling or balling up of products. Most products contain 1% of less of carbomer.
Cyclohexasiloxane is a type of silicone more commonly known as D6. It is an emollient and solvent.
Cyclohexasiloxane is used to evenly distribute ingredients throughout the product. When applied to the skin, Cyclohexasiloxane evaporates and leaves behind a silky feel.
As an emollient, it can help the skin feel soft and hydrated. It is also used to reduce frizz in hair products.
Learn more about CyclohexasiloxaneEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Disodium EDTA plays a role in making products more stable by aiding other preservatives.
It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.
Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.
Learn more about Disodium EDTAParfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
In the US, the alternative name for parfum is 'fragrance'.
The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumIngredient Ratings
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