La Roche-Posay Anthelios Uvmune 400 Ultra Invisible Fluid SPF 50+ Versus ISDIN Fusion Water Magic SPF 50
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningBis-Ethylhexyloxyphenol Methoxyphenyl Triazine
Skin ConditioningAlcohol Denat.
AntimicrobialEthylhexyl Triazone
UV AbsorberButyl Methoxydibenzoylmethane
UV AbsorberIsopropyl Palmitate
EmollientDiisopropyl Adipate
EmollientDicaprylyl Ether
EmollientGlycerin
HumectantPropanediol
SolventIsopropyl Myristate
EmollientC12-15 Alkyl Benzoate
AntimicrobialDiisopropyl Sebacate
EmollientC12-22 Alkyl Acrylate/Hydroxyethylacrylate Copolymer
StabilisingTocopherol
AntioxidantMethoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate
StabilisingPentylene Glycol
Skin ConditioningButyrospermum Parkii Butter
Skin ConditioningAcrylates Copolymer
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingCaprylyl Glycol
EmollientCitric Acid
BufferingDiethylamino Hydroxybenzoyl Hexyl Benzoate
UV FilterDrometrizole Trisiloxane
UV AbsorberHydroxyacetophenone
AntioxidantPhenylbenzimidazole Sulfonic Acid
UV AbsorberSodium Polyacrylate
AbsorbentTriethanolamine
BufferingTrisodium Ethylenediamine Disuccinate
Water, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Alcohol Denat., Ethylhexyl Triazone, Butyl Methoxydibenzoylmethane, Isopropyl Palmitate, Diisopropyl Adipate, Dicaprylyl Ether, Glycerin, Propanediol, Isopropyl Myristate, C12-15 Alkyl Benzoate, Diisopropyl Sebacate, C12-22 Alkyl Acrylate/Hydroxyethylacrylate Copolymer, Tocopherol, Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate, Pentylene Glycol, Butyrospermum Parkii Butter, Acrylates Copolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylyl Glycol, Citric Acid, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Drometrizole Trisiloxane, Hydroxyacetophenone, Phenylbenzimidazole Sulfonic Acid, Sodium Polyacrylate, Triethanolamine, Trisodium Ethylenediamine Disuccinate
Water
Skin ConditioningDibutyl Adipate
EmollientPropanediol
SolventEthylhexyl Salicylate
UV AbsorberEthylhexyl Triazone
UV AbsorberBis-Ethylhexyloxyphenol Methoxyphenyl Triazine
Skin ConditioningDimethicone
EmollientButyl Methoxydibenzoylmethane
UV AbsorberPhenylbenzimidazole Sulfonic Acid
UV AbsorberSilica
AbrasiveDiisopropyl Sebacate
EmollientArginine
MaskingPentylene Glycol
Skin ConditioningHydroxyacetophenone
AntioxidantLauryl PEG/PPG-18/18 Methicone
Skin ConditioningVp/Eicosene Copolymer
Polysorbate 60
EmulsifyingDimethicone/Vinyl Dimethicone Crosspolymer
Skin ConditioningGlycerin
HumectantCaprylyl Glycol
EmollientHydrated Silica
AbrasiveTocopheryl Acetate
AntioxidantPEG-10 Dimethicone
Skin ConditioningTetrasodium Glutamate Diacetate
Parfum
MaskingSclerotium Gum
Emulsion StabilisingSodium Hyaluronate
HumectantPorphyridium Cruentum Extract
Skin ConditioningXanthan Gum
EmulsifyingCitric Acid
BufferingWater, Dibutyl Adipate, Propanediol, Ethylhexyl Salicylate, Ethylhexyl Triazone, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Dimethicone, Butyl Methoxydibenzoylmethane, Phenylbenzimidazole Sulfonic Acid, Silica, Diisopropyl Sebacate, Arginine, Pentylene Glycol, Hydroxyacetophenone, Lauryl PEG/PPG-18/18 Methicone, Vp/Eicosene Copolymer, Polysorbate 60, Dimethicone/Vinyl Dimethicone Crosspolymer, Glycerin, Caprylyl Glycol, Hydrated Silica, Tocopheryl Acetate, PEG-10 Dimethicone, Tetrasodium Glutamate Diacetate, Parfum, Sclerotium Gum, Sodium Hyaluronate, Porphyridium Cruentum Extract, Xanthan Gum, Citric Acid
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
This ingredient is better known as bemotrizinol or Tinosorb S and is one of the best broad-spectrum UV filters in modern sunscreen.
It works by absorbing UV light across a whole range (280-400 nm) with peaks around 310 nm (UVB) and 340-345 nm (UVA). This means it covers UVB plus the deeper UVA wavelengths that drive photoaging and pigmentation.
Another pro?
It's exceptionally photostable, barely degrades in sunlight, and acts as a "bodyguard" for less stable filters.
That's why you'll see it paired with avobenzone or octinoxate; this team up ensures they keep working through sun exposure.
Safety reviews have been reassuring across the board. This ingredient shows low absorption through the skin, rarely irritates, and lab studies found it doesn't act like a hormone in the body (a concern that's been raised about some older sunscreen filters).
On maximum concentrations:
In 2026, the US F.D.A finally added it as an OTC sunscreen ingredient at concentrations up to 6% for adults / children 6 months and older
Learn more about Bis-Ethylhexyloxyphenol Methoxyphenyl TriazineAlso known as Avobenzone, this ingredient is an oil-soluble used to absorb the full spectrum of UVA rays (peak 357 nm).
It's one of the most effective UVA filters available but has a major caveat of photostability: avobenzone is susceptible to photodegradation.
This means it can lose efficacy when exposed to sunlight without the help of a stabilizing agent.
Studies show antioxidants (like vitamin E or vitamin C) and some UV filters (like octocrylene and Tinosorb S) can meaningfully improve its stability in a formulation.
The maximum allowable concentration according to regulation is 3% in the US + Canada, and 5% in the EU, Australia, China, Korea, and ASEAN countries.
It has a well-support safety profile: a comprehensive 2025 review found minimal toxicity with no evidence of carcinogenicity.
Overall, avobenzone is a safe and regulated ingredient used in sunscreen for over 40 years.
Learn more about Butyl MethoxydibenzoylmethaneCaprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolCitric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Read more about some other popular AHA's here:
Learn more about Citric AcidWe don't have a description for Diisopropyl Sebacate yet.
Ethylhexyl Triazone is a modern chemical sunscreen that protects from UV-B radiation.
It is the most effective of existing UV-B filters, as it provides the highest level of photo-stable absorption. It protects from the entire UV-B range (280 to 320nm), with it's highest level of protection at 314nm.
Ethylhexyl Triazone is oil soluble, oderless and colorless, which mean it is able to be incorporated into a variety of different formulations.
It is not currently available within the United States due to slow changing FDA regulations. Outside of the US, it is used in formulations at concentrations up to 5%.
Learn more about Ethylhexyl TriazoneGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinHydroxyacetophenone is antioxidant with skin conditioning and soothing properties. It also boosts the efficiency of preservatives.
Though naturally occuring in Norwegian spruce needles, this ingredient is usually synthetically created.
This ingredient is not irritating or sensitizing. Recent research also suggests it may have skin-brightening effects through tyrosinase inhibition.
Learn more about HydroxyacetophenonePentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolThis ingredient is more commonly known as Ensulizole, a chemical sunscreen ingredient.
Ensulizole mainly protects UV-B (290-340 nm) but offers a little UV-A (320-400 nm) protection. It is often paired with less photo-stable sunscreen ingredients due to its photo-stability.
Due to it being water-soluble, Ensulizole helps give sunscreens a light and non-oily texture.
Ensulizole is approved worldwide:
Learn more about Phenylbenzimidazole Sulfonic AcidPropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.Â
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water