This calming serum is formulated around Azelaic Acid and Zinc PCA to calm redness and clear breakouts.
This calming serum is formulated around Azelaic Acid and Panthenol to calm redness and clear breakouts.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Skin ConditioningAzelaic Acid
BufferingDipropylene Glycol
HumectantSodium Hydroxide
BufferingPentylene Glycol
Skin ConditioningPropanediol
Solvent1,2-Hexanediol
Skin ConditioningButylene Glycol
HumectantHydroxyacetophenone
AntioxidantCoptis Japonica Root Extract
Skin ConditioningTrisodium Ethylenediamine Disuccinate
ChelatingEthylhexylglycerin
Skin ConditioningPoloxamer 407
EmulsifyingMalachite Extract
AntioxidantArginine
MaskingAsiaticoside
AntioxidantAsiatic Acid
Skin ConditioningMadecassic Acid
Skin ConditioningHyaluronic Acid
HumectantHydrolyzed Hyaluronic Acid
HumectantSodium Hyaluronate
HumectantSodium Hyaluronate Crosspolymer
HumectantZinc PCA
HumectantAllantoin
Skin ConditioningCamellia Sinensis Leaf Extract
AntimicrobialPanthenol
Skin ConditioningGlycyrrhiza Glabra Root Extract
BleachingCentella Asiatica Extract
CleansingMelaleuca Alternifolia Leaf Extract
PerfumingWater, Azelaic Acid, Dipropylene Glycol, Sodium Hydroxide, Pentylene Glycol, Propanediol, 1,2-Hexanediol, Butylene Glycol, Hydroxyacetophenone, Coptis Japonica Root Extract, Trisodium Ethylenediamine Disuccinate, Ethylhexylglycerin, Poloxamer 407, Malachite Extract, Arginine, Asiaticoside, Asiatic Acid, Madecassic Acid, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Zinc PCA, Allantoin, Camellia Sinensis Leaf Extract, Panthenol, Glycyrrhiza Glabra Root Extract, Centella Asiatica Extract, Melaleuca Alternifolia Leaf Extract
Water
Skin ConditioningAzelaic Acid 12%
BufferingPropylene Glycol
HumectantSodium Hydroxide
BufferingEthoxydiglycol
HumectantPentylene Glycol
Skin ConditioningPanthenol
Skin ConditioningGlycerin
HumectantHydroxyethylcellulose
Emulsion Stabilising1,2-Hexanediol
Skin ConditioningEthylhexylglycerin
Skin ConditioningAllantoin
Skin ConditioningBiosaccharide Gum-1
HumectantButylene Glycol
HumectantBeta-Glucan
Skin ConditioningCynanchum Atratum Extract
Skin ConditioningAlthaea Rosea Flower Extract
Skin ConditioningTocopherol
AntioxidantArginine
MaskingBetaine
HumectantZinc Hydrolyzed Hyaluronate
HumectantZinc PCA
HumectantSodium DNA
Skin ConditioningCaprylic/Capric Triglyceride
MaskingPhosphatidylcholine
EmulsifyingCeramide NP
Skin ConditioningGlycine
BufferingGlutamic Acid
HumectantSerine
MaskingAlanine
MaskingLysine
Skin ConditioningProline
Skin ConditioningThreonine
Water, Azelaic Acid 12%, Propylene Glycol, Sodium Hydroxide, Ethoxydiglycol, Pentylene Glycol, Panthenol, Glycerin, Hydroxyethylcellulose, 1,2-Hexanediol, Ethylhexylglycerin, Allantoin, Biosaccharide Gum-1, Butylene Glycol, Beta-Glucan, Cynanchum Atratum Extract, Althaea Rosea Flower Extract, Tocopherol, Arginine, Betaine, Zinc Hydrolyzed Hyaluronate, Zinc PCA, Sodium DNA, Caprylic/Capric Triglyceride, Phosphatidylcholine, Ceramide NP, Glycine, Glutamic Acid, Serine, Alanine, Lysine, Proline, Threonine
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Learn more about AllantoinArginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.
It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.
A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.
Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.
One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.
Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.
Learn more about ArginineAzelaic acid is a multitasker ingredient that helps treat acne, pigmentation, and irritation. It is a great option for sensitive skin.
What makes it special?
OTC Azelaic acid is usually available in concentrations from 10-15% and anything over requires a prescription.
Here's what each tier does best:
Unlike other acids, azelaic acid will not make your skin more photosensitive/sun sensitive.
Though this ingredient is naturally occurring in grains like wheat, rye, and barley, it is usually synthetically created for cosmetics to ensure stability and effectiveness.
Learn more about Azelaic AcidButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinPanthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolPentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Learn more about Pentylene GlycolSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterZinc PCA is a clever two-in-one molecule: the zinc salt of pyrrolidone carboxylic acid (PCA).
Think of it as two useful things bonded together; the PCA half is one of your skin's own natural moisturizing factors (NMF) so it helps hold water in the upper layers. On the other hand, the zinc half does the heavy lifting on oil and bacteria.
The zinc part slows down an enzyme that turns testosterone into DHT, the hormone that tells your oil glands to pump out more sebum. Less of that signal means less oil. It also gently fights acne-causing bacteria and soothes redness/irritation.
This is why Zinc PCA often shows up in products for oily, breakout-prone skin and greasy scalps.
One lab study also hinted it might have a small anti-aging perk because it seemed to protect collagen from UVA damage and even helped the skin make a bit more of it. That last bit is still early research done in a dish and not real skin, so take it as a nice bonus rather than a promise for now.
As for scar healing, the picture is more "maybe" than a firm yes. Zinc itself plays a real role in wound repair because it is a cofactor for the enzymes involved in collagen building, calming inflammation, and helping new skin cells cover a wound. Lower zinc levels are also linked to slower healing.
Most of the scar healing research is on zinc oxide or oral zinc rather than zinc PCA specifically, with a focus on healing fresh wounds instead of scars that are already there.
Direct evidence that zinc PCA improves the look of established scars is still limited at this time. Though it would be fair to say zinc PCA supports the general skin-repair environment thanks to its zinc content .
This ingredient is water-soluble and plays nicely with other actives like niacinamide and salicylic acid. It works best at mildly acidic formulas (~4-6 pH) and is effective at low levels. Around 0.1% is enough to be active and finished products commonly use it anywhere up to 4%.
Overall, this is a well-tolerated, low-drama multitasker that suits oily and acne-prone skin.
Learn more about Zinc PCA