Dr. Denese SkinScience Hydroshield Pro Strength Serum Versus Nassif MD Hydro-Screen Hydrating Serum
Updated on March 03, 2025
Overview
What they are
These products are both cruelty-free and reef safe serums. They have a total of 9 ingredients in common
Cool Features
They both contain ceramides, retinoid, Vitamin C and Vitamin E
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any harsh alcohols, parabens or sulfates
What's Inside
They both contain silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Dr. Denese SkinScience Hydroshield Pro Strength Serum 20 ingredients
Nassif MD Hydro-Screen Hydrating Serum 34 ingredients
About this product
About this product
At a glance
Click on any of the items below to learn more
Dr. Denese SkinScience Hydroshield Pro Strength Serum 20 ingredients
Nassif MD Hydro-Screen Hydrating Serum 34 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Dimethicone
Emollient
Cyclopentasiloxane
Emollient
Caprylyl Methicone
Skin Conditioning
Dimethiconol
Emollient
Dimethicone Crosspolymer
Emulsion StabilisingTetrahexyldecyl Ascorbate
Antioxidant
Dimethicone/Vinyl Dimethicone Crosspolymer
Skin ConditioningPaphiopedilum Maudiae Flower Extract
Skin ConditioningHydroxypinacolone Retinoate
Skin Conditioning
Bisabolol
Masking
Zingiber Officinale Root Extract
MaskingCaprylic/Capric Triglyceride
MaskingDimethyl Isosorbide
SolventEthylhexyl Cocoate
Emollient
Glyceryl Linoleate
Emollient
Glyceryl Linolenate
Emollient
Tocopheryl Acetate
Antioxidant
Cholesterol
Emollient
Ceramide NP
Skin Conditioning
Phenoxyethanol
Preservative
Dimethicone, Cyclopentasiloxane, Caprylyl Methicone, Dimethiconol, Dimethicone Crosspolymer, Tetrahexyldecyl Ascorbate, Dimethicone/Vinyl Dimethicone Crosspolymer, Paphiopedilum Maudiae Flower Extract, Hydroxypinacolone Retinoate, Bisabolol, Zingiber Officinale Root Extract, Caprylic/Capric Triglyceride, Dimethyl Isosorbide, Ethylhexyl Cocoate, Glyceryl Linoleate, Glyceryl Linolenate, Tocopheryl Acetate, Cholesterol, Ceramide NP, Phenoxyethanol
Cyclopentasiloxane
Emollient
Cyclohexasiloxane
Emollient
Dimethiconol
Emollient
Dimethicone
Emollient
Caprylyl Methicone
Skin Conditioning
Ethylhexyl Palmitate
Emollient
Ethylhexyl Cocoate
Emollient
Retinol
Skin Conditioning
Bakuchiol
Antimicrobial
Tetrahexyldecyl Ascorbate
Antioxidant
Dimethylmethoxy Chromanol
Antioxidant
Sodium Hyaluronate
Humectant
Glycosphingolipids
EmollientCeramide NP
Skin Conditioning
Tocopherol
Antioxidant
Glycine Soja Oil
Emollient
Silica Dimethyl Silylate
EmollientButylene Glycol
Humectant
Pentylene Glycol
Skin ConditioningTocopheryl Acetate
Antioxidant
Parfum
Masking
Bisabolol
Masking
Tocotrienols
Skin ConditioningElaeis Guineensis Oil
Emollient
Lecithin
EmollientPhenyl Trimethicone
Skin Conditioning
Caprylyl Glycol
EmollientSqualene
Emollient
Beta-Sitosterol
Emulsion StabilisingOctadecenedioic Acid
Emulsifying
Acetic Acid
BufferingLinalool
Perfuming
Geraniol
Perfuming
Amyl Cinnamal
Perfuming
Cyclopentasiloxane, Cyclohexasiloxane, Dimethiconol, Dimethicone, Caprylyl Methicone, Ethylhexyl Palmitate, Ethylhexyl Cocoate, Retinol, Bakuchiol, Tetrahexyldecyl Ascorbate, Dimethylmethoxy Chromanol, Sodium Hyaluronate, Glycosphingolipids, Ceramide NP, Tocopherol, Glycine Soja Oil, Silica Dimethyl Silylate, Butylene Glycol, Pentylene Glycol, Tocopheryl Acetate, Parfum, Bisabolol, Tocotrienols, Elaeis Guineensis Oil, Lecithin, Phenyl Trimethicone, Caprylyl Glycol, Squalene, Beta-Sitosterol, Octadecenedioic Acid, Acetic Acid, Linalool, Geraniol, Amyl Cinnamal
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Dimethicone is a type of synthetic silicone created from natural materials such as quartz.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeCyclopentasiloxane, or D5, is a silicone used to improve texture of products and trap moisture.
D5 is considered lightweight and volatile. Volatile means it evaporates quickly after application. Once evaporated, D5 leaves a thin barrier that helps keep skin hydrated.
It is also an emollient. Emollients help soften the skin and prevent water loss. Silicones create a silky texture in products. D5 helps other ingredients become more spreadable.
Studies show D5 is safe to use in skincare products. We recommend speaking with a skincare professional if you have concerns.
Learn more about CyclopentasiloxaneCaprylyl Methicone is a type of silicone.
It helps soften and soothe the skin by creating a thin film on top. This film helps trap moisture, keeping your skin hydrated.
Dimethiconol is a silicone that resembles the popular dimethicone. Like other silicones, it is an emollient. Emollients create a thin film on skin to prevent moisture from escaping.
This ingredient helps to create a silky texture and improve spreadability. Due to its high molecular weight and thickness, it is often combined with cyclopentasiloxane.
Tetrahexyldecyl Ascorbate (THD) is a stable and oil-soluble form of Vitamin C.
THD is special in that it has the ability to travel deeper into skin than traditional ascorbic acid while maintaining the same skin benefits (double win!).
Because it’s oil-soluble, THD dives deep into your skin’s fatty layers (think ceramides and cholesterol) to fight off the kind of free radicals that mess with your skin barrier. This makes it a great pair with water-based vitamin C (ascorbic acid) that mainly works on the surface.
Even at just 0.1%, THD is already showing great antioxidant activity. When used up to 2%, it helps keep your skin happy and calm, especially when it’s stressed from pollution or sun.
Want to fade dark spots or tackle hyperpigmentation? You’ll want 5% or more. Pairing it with brightening buddies like niacinamide or licorice root gives even better results. One study even used 30% THD with other brighteners and saw real results on stubborn discoloration, even in melasma-prone skin.
A note on THD: It’s has a slightly silky, oily texture and usually shows up colorless or pale yellow (though the exact shade can vary by supplier).
While you can sneak it into water-based formulas, it really shines when paired with silicones or oils, which help your skin soak it up better.
THD is pretty stable, but it’s still vulnerable to degradation like ascorbic acid. Too much light or heat (above 113°F / 45°C) can break it down over time. Go for dark and opaque packaging that keeps it safe and shady!
Read more about other types of Vitamin C:
Learn more about Tetrahexyldecyl AscorbateBisabolol is famous for its skin soothing properties. It does this by blocking inflammatory signals, helping to reduce your body's reaction to irritation.
This ingredient also interferes with the process of hyperpigmentation. This can help with reducing dark spots and uneven tone.
Bisabolol is an antioxidant. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells. By fighting these free-radicals, Bisabolol may slow down signs of aging.
Studies have shown Bisabolol to have antimicrobial properties and may be a fungicide. These properties help preserve a product's shelf life.
All these properties makes bisabolol a great skin barrier helper ingredient.
Bisabolol also helps the absorption of other ingredients.
Note: Synthetic Bisabolol has been shown to be less effective.
Learn more about BisabololEthylhexyl Cocoate is created from 2-ethylhexanol and Coconut Acid. Coconut Acid is created from the fatty acids derived from Coconut Oil.
As an emollient, Ethylhexyl Cocoate helps soften and hydrate your skin. Emollients create a thin film on top of skin that traps moisture in.
Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateCeramide NP is a type of ceramide.
Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.
Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.
If you would like to eat ceramides, sweet potatoes contain a small amount.
Read more about other common types of ceramides here: Ceramide AP Ceramide EOP
Learn more about Ceramide NPIngredient Ratings
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