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Updated on June 13, 2024

Overview

Cool Features

They both contain Vitamin E

Suited For

They're both likely to be good for dry skin, brightening skin and sensitive skin

Free From

They both do not contain any parabens or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Differin Soothing Moisturizer
Differin Soothing Moisturizer
General Moisturizer
American Brand United States
Cetaphil Daily Oil-Free Moisturizer SPF 35

Ingredient Info

Click any item below to learn more and see relevant ingredients
spf rating
35

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Concerns

Notable Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Soothing Moisturizer
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Hydrogenated Polyisobutene Emollient, Skin Conditioning
1 / 2

Hydrogenated Polyisobutene is a synthetic polymer. Polymers are compounds with high molecular weight. Hydrogenated Polyisobutene is an emollient and texture enhancer.

1 Com. / 2 Irr.
Ceteareth-20 Cleansing, Emulsifying
2 / 3 May worsen Oily Skin Icon
May worsen Oily SkinMay worsen Oily Skin Icon

Ceteareth-20 is an emulsifier and cleansing agent. It is derived from cetearyl alcohol, a fatty alcohol.

2 Com. / 3 Irr.
Very Disliked Full details ->
Cetearyl Alcohol Emollient, Emulsifying, Emulsion Stabilising
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon
Fatty AlcoholFatty Alcohol Icon 3 Concerns

Cetearyl alcohol is a mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is mainly used as an emulsifier. Emulsifiers help prevent the separation of oils and products. Due to its composition, it can also be used to thicken a product or help create foam.

2 Com. / 1 Irr.
Very Disliked Full details ->
Persea Gratissima Oil Skin Conditioning
0-3 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon
OilOil Icon Helps hydrate Dry SkinHelps hydrate Dry Skin Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Persea Gratissima Oil is made by pressing dehydrated avocado fruit from the tree Persea gratissima, Lauraceae.

0-3 Com. / 0 Irr.
Disliked Full details ->
Tocopheryl Acetate Antioxidant, Skin Conditioning
0 / 0 Vitamin E IconAntioxidant IconHelps brighten skin Icon
Vitamin EVitamin E Icon AntioxidantAntioxidant Icon Helps brighten skinHelps brighten skin Icon

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

0 Com. / 0 Irr.
Dimethicone Emollient, Skin Conditioning, Skin Protecting
1 / 0 Silicon Icon
SiliconSilicon Icon

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

1 Com. / 0 Irr.
Very Disliked Full details ->
Panthenol Skin Conditioning
0 / 0 Helps reduce irritation Icon
Helps reduce irritationHelps reduce irritation Icon

Panthenol is a common ingredient that helps hydrate and soothe the skin. It can be found naturally in our skin and hair.

0 Com. / 0 Irr.
Citric Acid Buffering, Masking
AHA IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation IconMay worsen Rosacea Icon
AHAAHA Icon 4 Benefits 2 Concerns

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

Disliked Full details ->
Sodium Levulinate Skin Conditioning

Sodium levulinate is the a sodium salt of Levulinic Acid. If dissolved in an aqueous solution, the two ingredients become identical.

Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Benzyl Alcohol Perfuming, Preservative, Solvent
Alcohol IconFragrance IconPreservative IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon
AlcoholAlcohol Icon FragranceFragrance Icon PreservativePreservative Icon 6 Concerns

Benzyl Alcohol is most commonly used as a preservative. It also has a subtle, sweet smell. Small amounts of Benzyl Alcohol is not irritating and safe to use in skincare products. Most Benzyl Alcohol is derived from fruits such as apricots.

Very Disliked Full details ->
Stearoxytrimethylsilane Emollient, Skin Conditioning

We don't have a description for Stearoxytrimethylsilane.

Unknown Full details ->
Stearyl Alcohol Emollient, Emulsifying, Emulsion Stabilising
2 / 2 Fatty Alcohol Icon
Fatty AlcoholFatty Alcohol Icon

Stearyl Alcohol is a type of fatty alcohol from stearic acid. It is a white, waxy compound used to emulsify ingredients.

2 Com. / 2 Irr.
Very Disliked Full details ->
Acrylates/C10-30 Alkyl Acrylate Crosspolymer Emulsion Stabilising

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken and improve the texture of products.

Disliked Full details ->
Sodium Anisate Antimicrobial

Sodium Anisate comes from fennel. It is used as a preservative and to add flavoring.

Daily Oil-Free Moisturizer SPF 35
Butyl Methoxydibenzoylmethane UV Absorber, UV Filter
Chemical UV Filter IconMay cause irritation IconMay worsen Rosacea Icon
Chemical UV FilterChemical UV Filter Icon 2 Concerns

Also known as Avobenzone, this ingredient is a chemical sunscreen filter that provides protection in the UV-A range.

Very Disliked Full details ->
Homosalate Skin Conditioning, UV Absorber, UV Filter
Chemical UV Filter IconNon-Reef-Safe Icon
Chemical UV FilterChemical UV Filter Icon Non-Reef-SafeNon-Reef-Safe Icon

Homosalate is a chemical sunscreen filter that provides protection in the UV-B range (280nm - 320 nm), with a peak protection at 306 nm. It is internationally approved for use in sunscreens.

Very Disliked Full details ->
Ethylhexyl Salicylate UV Absorber, UV Filter
0 / 0 Chemical UV Filter IconNon-Reef-Safe IconMay worsen Rosacea Icon
Chemical UV FilterChemical UV Filter Icon 2 Concerns

Ethylhexyl Salicylate is an organic compound used to block UV rays. It primarily absorbs UVB rays but offers a small amount of UVA protection as well.

0 Com. / 0 Irr.
Disliked Full details ->
Octocrylene UV Absorber, UV Filter
Chemical UV Filter IconNon-Reef-Safe IconMay worsen Eczema Icon
Chemical UV FilterChemical UV Filter Icon 2 Concerns

Octocrylene protects skin from sun damage. It absorbs UV-B with peak absorption of 304 nm. It is a common sunscreen ingredient and often paired with avobenzone, a UVA filter. This is because octocrylene stabilizes other sunscreen ingredients by protecting them from degradation when exposed to sunlight. Octocrylene is a photostable ingredient and loses about 10% of SPF in 95 minutes.

Very Disliked Full details ->
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Dipropylene Glycol Masking, Solvent

Dipropylene Glycol is a synthetically created stabilizer and solvent. It is a part of the glycol class in the alcohol family.

Disliked Full details ->
Panthenol Skin Conditioning
0 / 0 Helps reduce irritation Icon
Helps reduce irritationHelps reduce irritation Icon

Panthenol is a common ingredient that helps hydrate and soothe the skin. It can be found naturally in our skin and hair.

0 Com. / 0 Irr.
Ethylhexyl Methoxycrylene Skin Conditioning

We don't have a description for Ethylhexyl Methoxycrylene.

Unknown Full details ->
Isopropyl Palmitate Emollient, Masking
3-4 / 1 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon
3 Concerns

Isopropyl Palmitate is a texture enhancer and emollient. It is an ester of isopropyl alcohol and palmitic acid.

3-4 Com. / 1 Irr.
Very Disliked Full details ->
Silica Abrasive, Absorbent
Exfoliant IconMay worsen Eczema IconMay worsen Rosacea Icon
ExfoliantExfoliant Icon 2 Concerns

Silica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.

Disliked Full details ->
Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Cetearyl Olivate
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Cetearyl Olivate is an emulsifier and texture enhancer. It is derived from the fatty acids of olive oil and Cetearyl alcohol, and is biodegradable.

Disliked Full details ->
Cetearyl Alcohol Emollient, Emulsifying, Emulsion Stabilising
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon
Fatty AlcoholFatty Alcohol Icon 3 Concerns

Cetearyl alcohol is a mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is mainly used as an emulsifier. Emulsifiers help prevent the separation of oils and products. Due to its composition, it can also be used to thicken a product or help create foam.

2 Com. / 1 Irr.
Very Disliked Full details ->
Glyceryl Stearate Emollient, Emulsifying
1 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Glyceryl Stearate is a mix of glycerin and stearic acid.

1 Com. / 0 Irr.
Disliked Full details ->
Potassium Cetyl Phosphate Emulsifying

Potassium Cetyl Phosphate is the potassium salt of a mixture. This mixture consists of the esters from phosphoricacid and cetyl alcohol.

Sorbitan Olivate Emulsifying
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Sorbitan Olivate is created from the fatty acids in olive oil and sorbitol.

Very Disliked Full details ->
Tocopheryl Acetate Antioxidant, Skin Conditioning
0 / 0 Vitamin E IconAntioxidant IconHelps brighten skin Icon
Vitamin EVitamin E Icon AntioxidantAntioxidant Icon Helps brighten skinHelps brighten skin Icon

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

0 Com. / 0 Irr.
Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Acrylates/C10-30 Alkyl Acrylate Crosspolymer Emulsion Stabilising

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken and improve the texture of products.

Disliked Full details ->
Palmitic Acid Emollient, Emulsifying
2 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon
2 Concerns

Palmitic Acid is a fatty acid found in our skin. In cosmetics, it is usually derived from palm oil. It is a cleanser, emollient, and emulsifier.

2 Com. / 0 Irr.
Very Disliked Full details ->
Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Leontopodium Alpinum Extract Skin Conditioning

We don't have a description for Leontopodium Alpinum Extract.

Unknown Full details ->
Stearic Acid Cleansing, Emulsifying, Emulsion Stabilising
2-3 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon
2 Concerns

Stearic Acid is a fatty acid. It is an emollient, emulsifier, and texture enhancer.

2-3 Com. / 0 Irr.
Very Disliked Full details ->
1,2-Hexanediol Skin Conditioning, Solvent

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

Oryza Sativa Lees Extract Skin Conditioning

We don't have a description for Oryza Sativa Lees Extract.

Unknown Full details ->
Propanediol Solvent

Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.

Sodium Hydroxide Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

Adenosine Skin Conditioning
Helps with Anti-Aging IconGood for Scar Healing Icon
2 Benefits

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Potassium Sorbate Preservative
Preservative Icon
PreservativePreservative Icon

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

Disliked Full details ->
Sodium Benzoate Masking, Preservative
Preservative Icon
PreservativePreservative Icon

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Disliked Full details ->
Citric Acid Buffering, Masking
AHA IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation IconMay worsen Rosacea Icon
AHAAHA Icon 4 Benefits 2 Concerns

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

Disliked Full details ->
Myristic Acid Cleansing, Emulsifying
3 / 0 Bad for Acne Prone Skin IconNot safe for Fungal Acne Icon
2 Concerns

Myristic Acid is a saturated fatty acid. It is naturally found in milk fat. Other sources include palm oil, coconut oil, and butter fat.

3 Com. / 0 Irr.
Very Disliked Full details ->
Buddleja Davidii Leaf Extract Skin Conditioning

Buddleja Davidii Leaf Extract is native to China and Japan. It is also known as the Butterfly Bush as it provides food for butterflies.

Unknown Full details ->
Thymus Vulgaris Leaf Extract Skin Protecting

We don't have a description for Thymus Vulgaris Leaf Extract.

Unknown Full details ->
Tocopherol Antioxidant, Masking, Skin Conditioning
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation Icon
Vitamin EVitamin E Icon AntioxidantAntioxidant Icon 4 Benefits May cause irritationMay cause irritation Icon

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

0-3 Com. / 0-3 Irr.

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Emollient, Emulsifying, Emulsion Stabilising
Very Disliked

Cetearyl alcohol is a mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is mainly used as an emulsifier. Emulsifiers help prevent the separation of oils and products. Due to its composition, it can also be used to thicken a product or help create foam.

Cetearyl alcohol is an emollient. Emollients help soothe and hydrate the skin by trapping moisture.

Studies show Cetearyl alcohol is non-toxic and non-irritating. The FDA allows products labeled "alcohol-free" to have fatty alcohols.

This ingredient is usually derived from plant oils such as palm, vegetable, or coconut oils. There is debate on whether this ingredient will cause acne.

Due to the fatty acid base, this ingredient may not be Malassezia folliculitis safe.

Learn more about Cetearyl Alcohol
Antioxidant, Skin Conditioning
Liked

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate
Skin Conditioning
Loved

Panthenol is a common ingredient that helps hydrate and soothe the skin. It can be found naturally in our skin and hair.

This ingredient is also referred to as pro-vitamin B5 or dexpanthenol in dermatology.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

Learn more about Panthenol
Buffering, Masking
Disliked

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and even out skin tone.

If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.

Read more about some other popular AHA's here:

Learn more about Citric Acid
Emollient, Humectant, Skin Conditioning
Liked

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol
Emulsion Stabilising
Disliked

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken and improve the texture of products.

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is also an emulsifier. Due to its properties, it can prevent water and oil ingredients from separating.

Ingredient Ratings

Here's what our community thinks of the ingredients in these two products.

Soothing Moisturizer
8
8
1
liked
mixed
disliked
not rated
Daily Oil-Free Moisturizer SPF 35
10
3
18
5
liked
mixed
disliked
not rated

When to use

23 Routines
48% use in am
52% use in pm
100% use every day
73 Routines
92% use in am
8% use in pm
99% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Differin Soothing Moisturizer 17 ingredients

Soothing Moisturizer hasn't been rated yet.
Rate it now

Cetaphil Daily Oil-Free Moisturizer SPF 35 36 ingredients

1.5 /5
from 2 ratings
Doesn't Work (1)
EmilyLennox_898's avatar

EmilyLennox_898

1 year ago · Sensitive Skin
Review

citric acid
My skin is so irritated and burns as soon as this goes on

madisonlane's avatar

Madison Lane

23 hours ago · Combination Skin
Review

I absolutely hate this stuff, it irritated everything and even my eyes. My father ended up trying it and the same thing happened to him.