Biretix Tri-Active Anti-Blemish Gel Versus Sesderma Azelac RU Liposomal Serum
Updated on February 18, 2025
Overview
What they are
These products are both cruelty-free and reef safe . They have a total of 7 ingredients in common
Cool Features
They both contain retinoid
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any parabens or sulfates
What's Inside
They both contain harsh alcohols
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Biretix Tri-Active Anti-Blemish Gel 26 ingredients
Sesderma Azelac RU Liposomal Serum 40 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
Biretix Tri-Active Anti-Blemish Gel 26 ingredients
Sesderma Azelac RU Liposomal Serum 40 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningAlcohol Denat.
Antimicrobial
Glycolic Acid 15%
Buffering
Niacinamide 5%
Smoothing
Propylene Glycol
Humectant
Salicylic Acid 2%
Masking
Ammonium Hydroxide
BufferingPolyquaternium-10
Retinol
Skin Conditioning
Hydroxypinacolone Retinoate
Skin Conditioning
Oligopeptide-10
Antimicrobial
Oryza Sativa Bran Extract
Skin Conditioning
Boswellia Serrata Extract
Skin ConditioningHoney Extract
Humectant
Butylene Glycol
Humectant
Ethylhexylglycerin
Skin ConditioningTetrasodium EDTA
Pentylene Glycol
Skin ConditioningPalmitoyl Hydroxypropyltrimonium Amylopectin/Glycerin Crosspolymer
Skin ConditioningDimethyl Isosorbide
Solvent1,2-Hexanediol
Skin Conditioning
Polysorbate 20
Emulsifying
Caprylyl Glycol
EmollientHydrogenated Lecithin
Emulsifying
BHT
Antioxidant
BHA
Antioxidant
Water, Alcohol Denat., Glycolic Acid 15%, Niacinamide 5%, Propylene Glycol, Salicylic Acid 2%, Ammonium Hydroxide, Polyquaternium-10, Retinol, Hydroxypinacolone Retinoate, Oligopeptide-10, Oryza Sativa Bran Extract, Boswellia Serrata Extract, Honey Extract, Butylene Glycol, Ethylhexylglycerin, Tetrasodium EDTA, Pentylene Glycol, Palmitoyl Hydroxypropyltrimonium Amylopectin/Glycerin Crosspolymer, Dimethyl Isosorbide, 1,2-Hexanediol, Polysorbate 20, Caprylyl Glycol, Hydrogenated Lecithin, BHT, BHA
Water
Skin ConditioningPropylene Glycol
Humectant
Lecithin
Emollient
Alcohol
Antimicrobial
Polymethyl Methacrylate
PEG-40 Hydrogenated Castor Oil
Emulsifying
4-Butylresorcinol
Antioxidant
Ascorbyl Glucoside
Antioxidant
Retinol
Skin Conditioning
Azelaic Acid
Buffering
Niacin
Smoothing
Undecylenoyl Phenylalanine
Skin ConditioningGlycyrrhetinic Acid
Skin ConditioningMorus Alba Root Extract
BleachingDiacetyl Boldine
Skin ConditioningPEG/PPG-20/6 Dimethicone
Emulsifying
Sodium Cholate
Skin ConditioningPolysorbate 20
Emulsifying
Xanthan Gum
EmulsifyingCarbomer
Emulsion StabilisingTriethanolamine
BufferingTocopheryl Acetate
Antioxidant
BHT
Antioxidant
Sodium Hydroxide
BufferingCaprylic/Capric Triglyceride
Masking
Sodium Chloride
Masking
Hydroxypropyl Cyclodextrin
MaskingBHA
Antioxidant
Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
Antioxidant
Triisopropanolamine
BufferingHydrochloric Acid
BufferingPhenoxyethanol
Preservative
Ethylhexylglycerin
Skin ConditioningParfum
Masking
Citronellyl Methylcrotonate
Masking
Citral
Perfuming
Coumarin
Perfuming
Eugenol
Perfuming
Limonene
Perfuming
Isoeugenol
Perfuming
Water, Propylene Glycol, Lecithin, Alcohol, Polymethyl Methacrylate, PEG-40 Hydrogenated Castor Oil, 4-Butylresorcinol, Ascorbyl Glucoside, Retinol, Azelaic Acid, Niacin, Undecylenoyl Phenylalanine, Glycyrrhetinic Acid, Morus Alba Root Extract, Diacetyl Boldine, PEG/PPG-20/6 Dimethicone, Sodium Cholate, Polysorbate 20, Xanthan Gum, Carbomer, Triethanolamine, Tocopheryl Acetate, BHT, Sodium Hydroxide, Caprylic/Capric Triglyceride, Sodium Chloride, Hydroxypropyl Cyclodextrin, BHA, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Triisopropanolamine, Hydrochloric Acid, Phenoxyethanol, Ethylhexylglycerin, Parfum, Citronellyl Methylcrotonate, Citral, Coumarin, Eugenol, Limonene, Isoeugenol
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterPropylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.
Another role of this ingredient is preventing a product from melting or freezing. Propylene glycol also adds antimicrobrial properties to a product, elongating product lifespan.
This ingredient is considered an organic alcohol and commonly added into both cosmetics and foods.
Those with sensitive skin or conditions may develop a rash when using this ingredient.
Learn more about Propylene GlycolRetinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
Why is retinol famous?
It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.
Retinol is proven to:
This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.
Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).
Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.
We recommend speaking with a medical professional about using this ingredient during pregnancy.
Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.
Read about Tretinoin
Learn more about RetinolEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.
Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.
The lauric acid used to create Polysorbate 20 is often derived from coconuts.
Polysorbate 20 may not be fungal acne safe.
Learn more about Polysorbate 20BHT is a synthetic antioxidant and preservative.
As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.
As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.
The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.
However, it was recently restricted for use in the UK as of April 2024.
Learn more about BHTThis BHA stands for butylated hydroxyanisole. If you are looking for the beta-hydroxy acid, aka as Salicylic Acid, click here.
In cosmetics, butylated hydroxyanisole is used as a perservative. It also has antioxidant properties. The concentrations usually used in skincare are low and do not penetrate through skin.
It is only considered a carcinogen when ingested.
Butylated Hydroxyanisole is a synthetic and waxy petrochemical. It is used as a preservative in foods and cosmetics.
Learn more about BHAIngredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Biretix Tri-Active Anti-Blemish Gel 26 ingredients
Sesderma Azelac RU Liposomal Serum 40 ingredients
Reviews
Here's what our community thinks
Biretix Tri-Active Anti-Blemish Gel 26 ingredients
Strongone
Strong enough for acne and wrinkles.
15% glycolic acid, 2% salicylic acid, 5% niacinamide, retinol! But.... unsafe for fungal acne due to polysorbate 20.
