Sesderma Azelac RU Liposomal Serum
A cruelty-free serum that contains retinoid, vitamin c and vitamin e.
Overview
What it is
Serum with 40 ingredients that contains retinoid, Vitamin C and Vitamin E
Cool Features
It is cruelty-free and reef safe
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any parabens or sulfates
Fun facts
Sesderma is from Spain. This product is used in 27 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
About this product
Ingredients List
Dive into the full list of ingredients.
Water
Skin ConditioningPropylene Glycol
HumectantLecithin
EmollientAlcohol
AntimicrobialPolymethyl Methacrylate
PEG-40 Hydrogenated Castor Oil
Emulsifying4-Butylresorcinol
AntioxidantAscorbyl Glucoside
AntioxidantRetinol
Skin ConditioningAzelaic Acid
BufferingNiacin
SmoothingUndecylenoyl Phenylalanine
Skin ConditioningGlycyrrhetinic Acid
Skin ConditioningMorus Alba Root Extract
BleachingDiacetyl Boldine
Skin ConditioningPEG/PPG-20/6 Dimethicone
EmulsifyingSodium Cholate
Skin ConditioningPolysorbate 20
EmulsifyingXanthan Gum
EmulsifyingCarbomer
Emulsion StabilisingTriethanolamine
BufferingTocopheryl Acetate
AntioxidantBHT
AntioxidantSodium Hydroxide
BufferingCaprylic/Capric Triglyceride
MaskingSodium Chloride
MaskingHydroxypropyl Cyclodextrin
MaskingBHA
AntioxidantPentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
AntioxidantTriisopropanolamine
BufferingHydrochloric Acid
BufferingPhenoxyethanol
PreservativeEthylhexylglycerin
Skin ConditioningParfum
MaskingCitronellyl Methylcrotonate
MaskingCitral
PerfumingCoumarin
PerfumingEugenol
PerfumingLimonene
PerfumingIsoeugenol
PerfumingWater, Propylene Glycol, Lecithin, Alcohol, Polymethyl Methacrylate, PEG-40 Hydrogenated Castor Oil, 4-Butylresorcinol, Ascorbyl Glucoside, Retinol, Azelaic Acid, Niacin, Undecylenoyl Phenylalanine, Glycyrrhetinic Acid, Morus Alba Root Extract, Diacetyl Boldine, PEG/PPG-20/6 Dimethicone, Sodium Cholate, Polysorbate 20, Xanthan Gum, Carbomer, Triethanolamine, Tocopheryl Acetate, BHT, Sodium Hydroxide, Caprylic/Capric Triglyceride, Sodium Chloride, Hydroxypropyl Cyclodextrin, BHA, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Triisopropanolamine, Hydrochloric Acid, Phenoxyethanol, Ethylhexylglycerin, Parfum, Citronellyl Methylcrotonate, Citral, Coumarin, Eugenol, Limonene, Isoeugenol
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterPropylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.
Another role of this ingredient is preventing a product from melting or freezing. Propylene glycol also adds antimicrobrial properties to a product, elongating product lifespan.
This ingredient is considered an organic alcohol and commonly added into both cosmetics and foods.
Those with sensitive skin or conditions may develop a rash when using this ingredient.
Learn more about Propylene GlycolLecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.
This ingredient has emollient and emulsifying properties.
As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.
As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.
This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.
Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.
We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.
Learn more about LecithinAlcohol comes in many different forms. Different types of alcohol will have different effects on skin. This ingredient is usually an astringent alcohol.
These alcohols are drying on the skin. They may strip away your skin's natural oils and even damage your skin barrier. Astringent alcohols may also irritate skin.
Other types of astringent alcohols include:
According to the National Rosacea Society based in the US, you should be mindful of products with these alcohols in the top half of ingredients.
Any type of sanitizing product will have high amounts of alcohol to help kill bacteria and viruses.
Fatty alcohols come from plant oils such as coconut oil. These can help hydrate the skin and are non-irritating. Some fatty alcohols include cetyl and stearyl alcohol.
Learn more about AlcoholWe don't have a description for Polymethyl Methacrylate yet.
Peg-40 Hydrogenated Castor Oil is derived from castor oil and polyethylene glycol (PEG). It is used as a emollient and emulsifier.
As an emulsifier, it helps prevent ingredients from separating. It also helps make the other ingredients more soluble; it is often used to solubilize fragrances. This increases spreadability and elongates shelf life in a product.
Emollients help soothe and soften the skin. They do this by creating a protective film on your skin. This barrier helps trap moisture and keeps your skin hydrated. Emollients may be effective at treating dry or itchy skin.
This ingredient may or may not be vegan, depending on the source.
Peg-40 Hydrogenated Castor Oil may not be fungal-acne safe. We recommend speaking with a professional if you have any questions or concerns.
Learn more about PEG-40 Hydrogenated Castor OilAlso known as Rucinol. It's an antioxidant primarily used to treat hyperpigmentation in the outermost layer of skin.
Hyperpigmentation occurs when an enzyme called tyrosinase triggers melanin production in the skin. Melanin is the pigment that gives skin, hair, and eyes their color.
Rucinol works by preventing tyrosinase from creating more melanin. According to a study from 2013, rucinol is more effective than other tyrosinase inhibitors such as hydroquinone, arbutin, and kojic acid.
According to a manufacturer, this ingredient is sensitive to air. Good formulations should account for this to keep your rucinol effective.
Learn more about 4-ButylresorcinolAscorbyl Glucoside is a stable form of Vitamin C. It is created by combining glucose from starch.
When applied to skin, Ascorbyl Glucoside turns into Ascorbic Acid.
Ascorbyl Glucoside is an antioxidant. Antioxidants help fight free-radicals, or molecules that may damage skin cells.
It can help to reduce redness, improve skin texture, reduce the effects of aging, reduce the visibility of dark spots, and brighten skin.
Read more about other types of Vitamin C:
Learn more about Ascorbyl GlucosideRetinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
Why is retinol famous?
It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.
Retinol is proven to:
This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.
Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).
Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.
We recommend speaking with a medical professional about using this ingredient during pregnancy.
Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.
Read about Tretinoin
Learn more about RetinolAzelaic acid is a naturally occurring acid derived from grains. This ingredient is effective in treating acne, rosacea, and other skin conditions.
It has been shown to reduce the growth of acne-causing bacteria and helps reduce inflammation. On top of that, it helps reduce the production of sebum and unclog pores.
Azelaic Acid also has antioxidant properties. Antioxidants protect our skin cells from free-radical damage.
One of the main benefits of azelaic acid is that it is gentle and well-tolerated by most people.
Fun fact: The lab-created form of azelaic acid is typically used within cosmetic products for its shelf-stability.
Learn more about Azelaic AcidNiacin is the other form of B3, with the other being niacinamide. The two have similar skin benefits: reducing inflammation, strengthening the skin barrier, and fading dark spots.
We don't have a description for Undecylenoyl Phenylalanine yet.
Glycyrrhetinic acid is a compound found in licorice. It has skin conditioning, skin soothing, antibacterial, and antioxidant properties.
Not only is this a great ingredient for soothing inflammation, studies show this compound is effective at protecting skin against UV-B induced damage.
Fun fact: This ingredient is also used to mask the bitter taste of medicine.
Learn more about Glycyrrhetinic AcidWe don't have a description for Morus Alba Root Extract yet.
We don't have a description for Diacetyl Boldine yet.
PEG/PPG-20/6 Dimethicone is a type of silicone.
We don't have a description for Sodium Cholate yet.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.
Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.
The lauric acid used to create Polysorbate 20 is often derived from coconuts.
Polysorbate 20 may not be fungal acne safe.
Learn more about Polysorbate 20Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumCarbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.
A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.
Triethanolamine is an emulsifier and pH adjuster. It is created using ethylene oxide and ammonia. This gives Triethanolamine a nitrogen core and a similar scent to ammonia.
As an emulsifier, it prevents ingredients from separating and enhances texture by adding volume to a product.
PH adjusters are common in cosmetic products. The pH of a product can affect the effectiveness of other ingredients. A product with a high pH may also irritate the skin.
Learn more about TriethanolamineTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateBHT is a synthetic antioxidant and preservative.
As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.
As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.
The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.
However, it was recently restricted for use in the UK as of April 2024.
Learn more about BHTSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideThis ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.
Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.
Learn more about Caprylic/Capric TriglycerideChances are, you eat sodium chloride every day. Sodium Chloride is also known as table salt.
This ingredient has many purposes in skincare: thickener, emulsifier, and exfoliator.
You'll most likely find this ingredient in cleansers where it is used to create a gel-like texture. As an emulsifier, it also prevents ingredients from separating.
There is much debate on whether this ingredient is comedogenic. The short answer - comedogenic ratings don't tell the whole story. Learn more about comegodenic ratings here.
The concensus about this ingredient causing acne seems to be divided. Research is needed to understand if this ingredient does cause acne.
Scrubs may use salt as the primary exfoliating ingredient.
Learn more about Sodium ChlorideWe don't have a description for Hydroxypropyl Cyclodextrin yet.
This BHA stands for butylated hydroxyanisole. If you are looking for the beta-hydroxy acid, aka as Salicylic Acid, click here.
In cosmetics, butylated hydroxyanisole is used as a perservative. It also has antioxidant properties. The concentrations usually used in skincare are low and do not penetrate through skin.
It is only considered a carcinogen when ingested.
Butylated Hydroxyanisole is a synthetic and waxy petrochemical. It is used as a preservative in foods and cosmetics.
Learn more about BHAPentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate (long name, huh?) is a synthetic antioxidant.
It is used to help stabilize other antioxidants or prevent the color from changing in a product.
As an antioxidant, it helps fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material. Thus, antioxidants may reduce the signs of aging.
This ingredient is oil-soluble.
Learn more about Pentaerythrityl Tetra-Di-T-Butyl HydroxyhydrocinnamateWe don't have a description for Triisopropanolamine yet.
Hydrochloric Acid can be found in the human body. It used to adjust pH levels of basic solutions.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumCitronellyl Methylcrotonate is a fragrance.
Citral is a fragrance and used to add a lemon-like scent to products. It is both naturally found in plants and created synthetically. In plants, it is commonly occurring in lemon myrtle, lemongrass, lemon tea-tree, lemon verbena, and other citruses.
The EU mandates Citral be listed separately as a fragrance. It is a known allergen and may cause contact dermatitis. Citral can also used as a masking ingredient.
The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.
The term 'citral' is a collective term for two geometric isomers: geranial/Citral A and neral/Citral B.
Learn more about CitralCoumarins are a group of substances found naturally in plants. There are over 1300 types of coumarins identified. It has a natural vanilla scent.
Coumarin is an identified EU known allergy, meaning it may cause an allergic reaction when applied to the skin.
In many countries, coumarin is banned as a food additive. However, it can be found in soaps, tobacco products, and some alcohol drinks.
Plants use coumarins as a chemical defense. Some plants that have coumarins include lavender, tonka beans, and yellow clovers.
Learn more about CoumarinEugenol is naturally found in cloves, basil, and bay leaves. It is an aromatic oil used to add fragrance to a product. The scent of eugenol is described as "clove-like". Eugenol is a known EU allergen, meaning it causes contact allergies.
Studies show eugenol possesses antibacterial and antioxidant properties.
Besides cosmetics, eugenol is also added as a flavor in teas and cakes.
Learn more about EugenolLimonene is a fragrance that adds scent and taste to a formulation.
It's found in the peel oil of citrus fruits and other plants such as lavender and eucalyptus. The scent of limonene is generally described as "sweet citrus".
Limonene acts as an antioxidant, meaning it helps neutralize free radicals.
When exposed to air, oxidized limonene may sensitize the skin. Because of this, limonene is often avoided by people with sensitive skin.
The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.
Learn more about LimoneneIsoeugenol is a fragrance component that is naturally occurring in plants such as ylang-ylang, nutmeg, and cinnamon.
Isoeugenol is a known EU allergen. This means it is known to cause an allergic reaction when applied to the skin.
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Where it's from
Sesderma is a Spanish brand
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We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Published November 16, 2022 • Added by danielariberto_723